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Platelet-derived growth factor receptor-alpha-positive myeloid neoplasm presenting as eosinophilic gastrointestinal disease.

Constantine GM, Ware J, Brown T, Thumm L, Kamal N, Kumar S, Kleiner D, Maric I, Klion AD.

J Allergy Clin Immunol Pract. 2020 Feb 11. pii: S2213-2198(20)30142-2. doi: 10.1016/j.jaip.2020.01.055. [Epub ahead of print] No abstract available.


Predictors of left ventricular remodelling in patients with dilated cardiomyopathy - a cardiovascular magnetic resonance study.

Tayal U, Wage R, Newsome S, Manivarmane R, Izgi C, Muthumala A, Dungu JN, Assomull R, Hatipoglu S, Halliday BP, Lota AS, Ware JS, Gregson J, Frenneaux M, Cook SA, Pennell DJ, Scott AD, Cleland JGF, Prasad SK.

Eur J Heart Fail. 2020 Feb 13. doi: 10.1002/ejhf.1734. [Epub ahead of print]


Diagnostic yield of hypertrophic cardiomyopathy in first-degree relatives of decedents with idiopathic left ventricular hypertrophy.

Finocchiaro G, Dhutia H, Gray B, Ensam B, Papatheodorou S, Miles C, Malhotra A, Fanton Z, Bulleros P, Homfray T, Witney AA, Bunce N, Anderson LJ, Ware JS, Sharma R, Tome M, Behr ER, Sheppard MN, Papadakis M, Sharma S.

Europace. 2020 Feb 3. pii: euaa012. doi: 10.1093/europace/euaa012. [Epub ahead of print]


An International, Multicentered, Evidence-Based Reappraisal of Genes Reported to Cause Congenital Long QT Syndrome.

Adler A, Novelli V, Amin AS, Abiusi E, Care M, Nannenberg EA, Feilotter H, Amenta S, Mazza D, Bikker H, Sturm AC, Garcia J, Ackerman MJ, Hershberger RE, Perez MV, Zareba W, Ware JS, Wilde AAM, Gollob MH.

Circulation. 2020 Feb 11;141(6):418-428. doi: 10.1161/CIRCULATIONAHA.119.043132. Epub 2020 Jan 27.


Reevaluating the Genetic Contribution of Monogenic Dilated Cardiomyopathy.

Mazzarotto F, Tayal U, Buchan RJ, Midwinter W, Wilk A, Whiffin N, Govind R, Mazaika E, de Marvao A, Dawes TJW, Felkin LE, Ahmad M, Theotokis PI, Edwards E, Ing AY, Thomson KL, Chan LLH, Sim D, Baksi AJ, Pantazis A, Roberts AM, Watkins H, Funke B, O'Regan DP, Olivotto I, Barton PJR, Prasad SK, Cook SA, Ware JS, Walsh R.

Circulation. 2020 Feb 4;141(5):387-398. doi: 10.1161/CIRCULATIONAHA.119.037661. Epub 2020 Jan 27.


The Clock Keeps Ticking: Circadian Rhythms of Free-Ranging Polar Bears.

Ware JV, Rode KD, Robbins CT, Leise T, Weil CR, Jansen HT.

J Biol Rhythms. 2020 Apr;35(2):180-194. doi: 10.1177/0748730419900877. Epub 2020 Jan 24.


PET molecular imaging of phosphodiesterase 10A: An early biomarker of Huntington's disease progression.

Fazio P, Fitzer-Attas CJ, Mrzljak L, Bronzova J, Nag S, Warner JH, Landwehrmeyer B, Al-Tawil N, Halldin C, Forsberg A, Ware J, Dilda V, Wood A, Sampaio C, Varrone A; PEARL-HD and LONGPDE10 study collaborators.

Mov Disord. 2020 Jan 22. doi: 10.1002/mds.27963. [Epub ahead of print]


Genomic variant sharing: a position statement.

Wright CF, Ware JS, Lucassen AM, Hall A, Middleton A, Rahman N, Ellard S, Firth HV.

Wellcome Open Res. 2019 Feb 5;4:22. doi: 10.12688/wellcomeopenres.15090.2. eCollection 2019.


Intrinsic and Extrinsic Pharmacokinetic Variability of Small Molecule Targeted Cancer Therapy.

Reyner E, Lum B, Jing J, Kagedal M, Ware JA, Dickmann LJ.

Clin Transl Sci. 2019 Nov 15. doi: 10.1111/cts.12726. [Epub ahead of print]


Should we be euthanasing cancer patients?

Ware J, Clutton E, Murphy K, Taylor P.

Vet Rec. 2019 Nov 9;185(18):574. doi: 10.1136/vr.l6364. No abstract available.


Public perception of coastal habitat loss and habitat creation using artificial floating islands in the UK.

Ware J, Callaway R.

PLoS One. 2019 Oct 31;14(10):e0224424. doi: 10.1371/journal.pone.0224424. eCollection 2019.


Sleep apnea and kidney transplant outcomes: findings from a 20-year (1997-2017) historical cohort study.

Lubas MM, Ware JC, Szklo-Coxe M.

Sleep Med. 2019 Nov;63:151-158. doi: 10.1016/j.sleep.2019.05.014. Epub 2019 Jun 12.


Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study.

Bagley SJ, Nabavizadeh SA, Mays JJ, Till JE, Ware JB, Levy S, Sarchiapone W, Hussain J, Prior T, Guiry S, Christensen T, Yee SS, Nasrallah MP, Morrissette JJD, Binder ZA, O'Rourke DM, Cucchiara AJ, Brem S, Desai AS, Carpenter EL.

Clin Cancer Res. 2020 Jan 15;26(2):397-407. doi: 10.1158/1078-0432.CCR-19-2533. Epub 2019 Oct 30.


Association of platelet function with depression and its treatment with sertraline in patients with chronic kidney disease: analysis of a randomized trial.

Jain N, Wan F, Kothari M, Adelodun A, Ware J, Sarode R, Hedayati SS.

BMC Nephrol. 2019 Oct 29;20(1):395. doi: 10.1186/s12882-019-1576-7.


Mechanisms of glucocorticoid resistance in hypereosinophilic syndromes.

Stokes K, Yoon P, Makiya M, Gebreegziabher M, Holland-Thomas N, Ware J, Wetzler L, Khoury P, Klion AD.

Clin Exp Allergy. 2019 Dec;49(12):1598-1604. doi: 10.1111/cea.13509. Epub 2019 Oct 27.


Natural History of Treated Subarachnoid Neurocysticercosis.

Nash TE, O'Connell EM, Hammoud DA, Wetzler L, Ware JM, Mahanty S.

Am J Trop Med Hyg. 2020 Jan;102(1):78-89. doi: 10.4269/ajtmh.19-0436.


Academy of Breastfeeding Medicine Liaisons-Building Relationships.

Tobolic T, Ware J.

Breastfeed Med. 2019 Oct;14(8):609-610. doi: 10.1089/bfm.2019.29137.tjt. Epub 2019 Sep 24. No abstract available.


The yield of postmortem genetic testing in sudden death cases with structural findings at autopsy.

Lahrouchi N, Raju H, Lodder EM, Papatheodorou S, Miles C, Ware JS, Papadakis M, Tadros R, Cole D, Skinner JR, Crawford J, Love DR, Pua CJ, Soh BY, Bhalshankar JD, Govind R, Tfelt-Hansen J, Winkel BG, van der Werf C, Wijeyeratne YD, Mellor G, Till J, Cohen M, Tome-Esteban M, Sharma S, Wilde AAM, Cook SA, Sheppard MN, Bezzina CR, Behr ER.

Eur J Hum Genet. 2020 Jan;28(1):17-22. doi: 10.1038/s41431-019-0500-8. Epub 2019 Sep 18.


Seasonally Resolved Excess Urban Methane Emissions from the Baltimore/Washington, DC Metropolitan Region.

Huang Y, Kort EA, Gourdji S, Karion A, Mueller K, Ware J.

Environ Sci Technol. 2019 Oct 1;53(19):11285-11293. doi: 10.1021/acs.est.9b02782. Epub 2019 Sep 19.


Improving the Understanding of Genetic Variants in Rare Disease With Large-scale Reference Populations.

Whiffin N, Ware JS, O'Donnell-Luria A.

JAMA. 2019 Aug 30. doi: 10.1001/jama.2019.12891. [Epub ahead of print] No abstract available.


Role of Targeted Therapy in Dilated Cardiomyopathy: The Challenging Road Toward a Personalized Approach.

Verdonschot JAJ, Hazebroek MR, Ware JS, Prasad SK, Heymans SRB.

J Am Heart Assoc. 2019 Jun 4;8(11):e012514. doi: 10.1161/JAHA.119.012514. Epub 2019 Jun 1. No abstract available.


Next-generation sequencing using microfluidic PCR enrichment for molecular autopsy.

Raju H, Ware JS, Skinner JR, Hedley PL, Arno G, Love DR, van der Werf C, Tfelt-Hansen J, Winkel BG, Cohen MC, Li X, John S, Sharma S, Jeffery S, Wilde AAM, Christiansen M, Sheppard MN, Behr ER.

BMC Cardiovasc Disord. 2019 Jul 23;19(1):174. doi: 10.1186/s12872-019-1154-8.


Pathophysiology 2: The Role of Platelets in Cancer Biology.

Franco AT, Ware J.

Cancer Treat Res. 2019;179:37-54. doi: 10.1007/978-3-030-20315-3_3.


Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes.

Chen J, Loukola A, Gillespie NA, Peterson R, Jia P, Riley B, Maes H, Dick DM, Kendler KS, Damaj MI, Miles MF, Zhao Z, Li MD, Vink JM, Minica CC, Willemsen G, Boomsma DI, Qaiser B, Madden PAF, Korhonen T, Jousilahti P, Hällfors J, Gelernter J, Kranzler HR, Sherva R, Farrer L, Maher B, Vanyukov M, Taylor M, Ware JJ, Munafò MR, Lutz SM, Hokanson JE, Gu F, Landi MT, Caporaso NE, Hancock DB, Gaddis NC, Baker TB, Bierut LJ, Johnson EO, Chenoweth M, Lerman C, Tyndale R, Kaprio J, Chen X.

Nicotine Tob Res. 2019 Jul 11. pii: ntz099. doi: 10.1093/ntr/ntz099. [Epub ahead of print]


Association of Titin-Truncating Genetic Variants With Life-threatening Cardiac Arrhythmias in Patients With Dilated Cardiomyopathy and Implanted Defibrillators.

Corden B, Jarman J, Whiffin N, Tayal U, Buchan R, Sehmi J, Harper A, Midwinter W, Lascelles K, Markides V, Mason M, Baksi J, Pantazis A, Pennell DJ, Barton PJ, Prasad SK, Wong T, Cook SA, Ware JS.

JAMA Netw Open. 2019 Jun 5;2(6):e196520. doi: 10.1001/jamanetworkopen.2019.6520.


Arterial Spin Labeling and Dynamic Susceptibility Contrast-enhanced MR Imaging for evaluation of arteriovenous shunting and tumor hypoxia in glioblastoma.

Nabavizadeh SA, Akbari H, Ware JB, Nasrallah M, Guiry S, Bagley SJ, Desai A, Levy S, Sarchiapone W, Prior T, Detre J, Wolf RL, O'Rourke DM, Brem S, Davatzikos C.

Sci Rep. 2019 Jun 19;9(1):8747. doi: 10.1038/s41598-019-45312-x.


Associations Between Breastfeeding Initiation and Infant Mortality in an Urban Population.

Ware JL, Chen A, Morrow AL, Kmet J.

Breastfeed Med. 2019 Sep;14(7):465-474. doi: 10.1089/bfm.2019.0067. Epub 2019 Jun 17.


Vitamin D Supplementation and Prevention of Type 2 Diabetes.

Pittas AG, Dawson-Hughes B, Sheehan P, Ware JH, Knowler WC, Aroda VR, Brodsky I, Ceglia L, Chadha C, Chatterjee R, Desouza C, Dolor R, Foreyt J, Fuss P, Ghazi A, Hsia DS, Johnson KC, Kashyap SR, Kim S, LeBlanc ES, Lewis MR, Liao E, Neff LM, Nelson J, O'Neil P, Park J, Peters A, Phillips LS, Pratley R, Raskin P, Rasouli N, Robbins D, Rosen C, Vickery EM, Staten M; D2d Research Group.

N Engl J Med. 2019 Aug 8;381(6):520-530. doi: 10.1056/NEJMoa1900906. Epub 2019 Jun 7.


Review of Molecular Identification Techniques for Forensically Important Diptera.

Gemmellaro MD, Hamilton GC, Ware JL.

J Med Entomol. 2019 Jun 27;56(4):887-902. doi: 10.1093/jme/tjz040.


Early Neurodevelopmental Outcomes in Children Supported with ECMO for Cardiac Indications.

Sadhwani A, Cheng H, Stopp C, Rollins CK, Jolley MA, Dunbar-Masterson C, Wypij D, Newburger J, Ware J, Thiagarajan RR.

Pediatr Cardiol. 2019 Jun;40(5):1072-1083. doi: 10.1007/s00246-019-02115-1. Epub 2019 May 11.


Intrinsic modifiable risk factors in ballet dancers: Applying evidence based practice principles to enhance clinical applications.

Campbell RS, Lehr ME, Livingston A, McCurdy M, Ware JK.

Phys Ther Sport. 2019 Jul;38:106-114. doi: 10.1016/j.ptsp.2019.04.022. Epub 2019 May 1. Review.


Evaluation of the Drug-Drug Interaction Potential of Acalabrutinib and Its Active Metabolite, ACP-5862, Using a Physiologically-Based Pharmacokinetic Modeling Approach.

Zhou D, Podoll T, Xu Y, Moorthy G, Vishwanathan K, Ware J, Slatter JG, Al-Huniti N.

CPT Pharmacometrics Syst Pharmacol. 2019 Jul;8(7):489-499. doi: 10.1002/psp4.12408. Epub 2019 May 12.


Molecular Identity of Holomastigotes (Spirotrichonymphea, Parabasalia) with Descriptions of Holomastigotes flavipes n. sp. and Holomastigotes tibialis n. sp.

Taerum SJ, Jasso-Selles DE, Wilson M, Ware JL, Sillam-Dussès D, Šobotník J, Gile GH.

J Eukaryot Microbiol. 2019 Nov;66(6):882-891. doi: 10.1111/jeu.12739. Epub 2019 May 16.


Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy.

Garcia-Pavia P, Kim Y, Restrepo-Cordoba MA, Lunde IG, Wakimoto H, Smith AM, Toepfer CN, Getz K, Gorham J, Patel P, Ito K, Willcox JA, Arany Z, Li J, Owens AT, Govind R, Nuñez B, Mazaika E, Bayes-Genis A, Walsh R, Finkelman B, Lupon J, Whiffin N, Serrano I, Midwinter W, Wilk A, Bardaji A, Ingold N, Buchan R, Tayal U, Pascual-Figal DA, de Marvao A, Ahmad M, Garcia-Pinilla JM, Pantazis A, Dominguez F, John Baksi A, O'Regan DP, Rosen SD, Prasad SK, Lara-Pezzi E, Provencio M, Lyon AR, Alonso-Pulpon L, Cook SA, DePalma SR, Barton PJR, Aplenc R, Seidman JG, Ky B, Ware JS, Seidman CE.

Circulation. 2019 Jul 2;140(1):31-41. doi: 10.1161/CIRCULATIONAHA.118.037934. Epub 2019 Apr 16.


Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor.

Ma S, Suchomel J, Yanez E, Yost E, Liang X, Zhu R, Le H, Siebers N, Joas L, Morley R, Royer-Joo S, Pirzkall A, Salphati L, Ware JA, Morrissey KM.

Br J Clin Pharmacol. 2019 Aug;85(8):1751-1760. doi: 10.1111/bcp.13961. Epub 2019 Jun 14.


An integrative phylogenomic approach illuminates the evolutionary history of cockroaches and termites (Blattodea).

Evangelista DA, Wipfler B, Béthoux O, Donath A, Fujita M, Kohli MK, Legendre F, Liu S, Machida R, Misof B, Peters RS, Podsiadlowski L, Rust J, Schuette K, Tollenaar W, Ware JL, Wappler T, Zhou X, Meusemann K, Simon S.

Proc Biol Sci. 2019 Jan 30;286(1895):20182076. doi: 10.1098/rspb.2018.2076.


Benralizumab for PDGFRA-Negative Hypereosinophilic Syndrome.

Kuang FL, Legrand F, Makiya M, Ware J, Wetzler L, Brown T, Magee T, Piligian B, Yoon P, Ellis JH, Sun X, Panch SR, Powers A, Alao H, Kumar S, Quezado M, Yan L, Lee N, Kolbeck R, Newbold P, Goldman M, Fay MP, Khoury P, Maric I, Klion AD.

N Engl J Med. 2019 Apr 4;380(14):1336-1346. doi: 10.1056/NEJMoa1812185.


Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.

Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M.

Nat Med. 2019 Apr;25(4):641-655. doi: 10.1038/s41591-019-0379-5. Epub 2019 Apr 1.


Improving CKD-Specific Patient-Reported Measures of Health-Related Quality of Life.

Ware JE Jr, Richardson MM, Meyer KB, Gandek B.

J Am Soc Nephrol. 2019 Apr;30(4):664-677. doi: 10.1681/ASN.2018080814. Epub 2019 Mar 21.


Memantine for dementia.

McShane R, Westby MJ, Roberts E, Minakaran N, Schneider L, Farrimond LE, Maayan N, Ware J, Debarros J.

Cochrane Database Syst Rev. 2019 Mar 20;3:CD003154. doi: 10.1002/14651858.CD003154.pub6.


Response by Ho et al to Letter Regarding Article, "Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)".

Ho CY, Day SM, Ashley EA, Michels M, Pereira AC, Jacoby D, Lakdawala NK, Ware JS, Helms AS, Colan SD, Seidman CE, Olivotto I; SHaRe Investigators.

Circulation. 2019 Mar 19;139(12):1559-1560. doi: 10.1161/CIRCULATIONAHA.118.039069. No abstract available.


Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery.

Garg S, Sadhukhan R, Banerjee S, Savenka AV, Basnakian AG, McHargue V, Wang J, Pawar SA, Ghosh SP, Ware J, Hauer-Jensen M, Pathak R.

Antioxidants (Basel). 2019 Mar 6;8(3). pii: E57. doi: 10.3390/antiox8030057.


Reader response: Evaluating depression and suicidality in tetrabenazine users with Huntington disease.

Sampaio C, Ware JJ, Macleod M, Wagenmakers EJ, Munafò M.

Neurology. 2019 Feb 26;92(9):447-448. doi: 10.1212/WNL.0000000000006999. No abstract available.


A 12-item short form of the Knee injury and Osteoarthritis Outcome Score (KOOS-12): tests of reliability, validity and responsiveness.

Gandek B, Roos EM, Franklin PD, Ware JE Jr.

Osteoarthritis Cartilage. 2019 May;27(5):762-770. doi: 10.1016/j.joca.2019.01.011. Epub 2019 Feb 1.


Sudden Death and Left Ventricular Involvement in Arrhythmogenic Cardiomyopathy.

Miles C, Finocchiaro G, Papadakis M, Gray B, Westaby J, Ensam B, Basu J, Parry-Williams G, Papatheodorou E, Paterson C, Malhotra A, Robertus JL, Ware JS, Cook SA, Asimaki A, Witney A, Ster IC, Tome M, Sharma S, Behr ER, Sheppard MN.

Circulation. 2019 Apr 9;139(15):1786-1797. doi: 10.1161/CIRCULATIONAHA.118.037230.


Quantitative approaches to variant classification increase the yield and precision of genetic testing in Mendelian diseases: the case of hypertrophic cardiomyopathy.

Walsh R, Mazzarotto F, Whiffin N, Buchan R, Midwinter W, Wilk A, Li N, Felkin L, Ingold N, Govind R, Ahmad M, Mazaika E, Allouba M, Zhang X, de Marvao A, Day SM, Ashley E, Colan SD, Michels M, Pereira AC, Jacoby D, Ho CY, Thomson KL, Watkins H, Barton PJR, Olivotto I, Cook SA, Ware JS.

Genome Med. 2019 Jan 29;11(1):5. doi: 10.1186/s13073-019-0616-z.


Evaluating the Clinical Validity of Hypertrophic Cardiomyopathy Genes.

Ingles J, Goldstein J, Thaxton C, Caleshu C, Corty EW, Crowley SB, Dougherty K, Harrison SM, McGlaughon J, Milko LV, Morales A, Seifert BA, Strande N, Thomson K, Peter van Tintelen J, Wallace K, Walsh R, Wells Q, Whiffin N, Witkowski L, Semsarian C, Ware JS, Hershberger RE, Funke B.

Circ Genom Precis Med. 2019 Feb;12(2):e002460. doi: 10.1161/CIRCGEN.119.002460.


Using High-Resolution Variant Frequencies Empowers Clinical Genome Interpretation and Enables Investigation of Genetic Architecture.

Whiffin N, Roberts AM, Minikel E, Zappala Z, Walsh R, O'Donnell-Luria AH, Karczewski KJ, Harrison SM, Thomson KL, Sage H, Ing AY, Barton PJR, Funke B, Cook SA, MacArthur DG, Ware JS.

Am J Hum Genet. 2019 Jan 3;104(1):187-190. doi: 10.1016/j.ajhg.2018.11.012. No abstract available.


Etanercept to Control Inflammation in the Treatment of Complicated Neurocysticercosis.

Nash TE, Ware JM, Coyle CM, Mahanty S.

Am J Trop Med Hyg. 2019 Mar;100(3):609-616. doi: 10.4269/ajtmh.18-0795.


Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis.

Asfari A, Dent JA, Corken A, Herington D, Kaliki V, Sra N, Hefley G, Pasala S, Prodhan P, Ware J.

Thromb Haemost. 2019 Mar;119(3):431-438. doi: 10.1055/s-0038-1676794. Epub 2018 Dec 31.


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