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Evidence of oxidative stress and mitochondrial dysfunction in spinocerebellar ataxia type 2 (SCA2) patient fibroblasts: Effect of coenzyme Q10 supplementation on these parameters.

Cornelius N, Wardman JH, Hargreaves IP, Neergheen V, Bie AS, Tümer Z, Nielsen JE, Nielsen TT.

Mitochondrion. 2017 May;34:103-114. doi: 10.1016/j.mito.2017.03.001. Epub 2017 Mar 3.


Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake.

Wardman JH, Gomes I, Bobeck EN, Stockert JA, Kapoor A, Bisignano P, Gupta A, Mezei M, Kumar S, Filizola M, Devi LA.

Sci Signal. 2016 May 31;9(430):ra55. doi: 10.1126/scisignal.aac8035.


ProSAAS-derived peptides are differentially processed and sorted in mouse brain and AtT-20 cells.

Wardman JH, Fricker LD.

PLoS One. 2014 Aug 22;9(8):e104232. doi: 10.1371/journal.pone.0104232. eCollection 2014.


GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding.

Gomes I, Aryal DK, Wardman JH, Gupta A, Gagnidze K, Rodriguiz RM, Kumar S, Wetsel WC, Pintar JE, Fricker LD, Devi LA.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16211-6. doi: 10.1073/pnas.1312938110. Epub 2013 Sep 16.


ProSAAS-derived peptides are colocalized with neuropeptide Y and function as neuropeptides in the regulation of food intake.

Wardman JH, Berezniuk I, Di S, Tasker JG, Fricker LD.

PLoS One. 2011;6(12):e28152. doi: 10.1371/journal.pone.0028152. Epub 2011 Dec 2.


Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics.

Wardman JH, Zhang X, Gagnon S, Castro LM, Zhu X, Steiner DF, Day R, Fricker LD.

J Neurochem. 2010 Jul;114(1):215-25. doi: 10.1111/j.1471-4159.2010.06760.x. Epub 2010 Apr 19.

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