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Items: 48

1.

[An intriguing immunohistochemical expression profile for an adenosquamous carcinoma].

Lépine C, Kapfer J, El Ward Y, Badoual C.

Ann Pathol. 2019 Jun 25. pii: S0242-6498(19)30095-1. doi: 10.1016/j.annpat.2019.04.008. [Epub ahead of print] French. No abstract available.

PMID:
31253458
2.

Platelets Promote Metastasis via Binding Tumor CD97 Leading to Bidirectional Signaling that Coordinates Transendothelial Migration.

Ward Y, Lake R, Faraji F, Sperger J, Martin P, Gilliard C, Ku KP, Rodems T, Niles D, Tillman H, Yin J, Hunter K, Sowalsky AG, Lang J, Kelly K.

Cell Rep. 2018 Apr 17;23(3):808-822. doi: 10.1016/j.celrep.2018.03.092.

3.

Use of Ciliogenesis to Detect Aneugens: The Role of Primary Cilia.

Divi KV, Ward Y, Poirier MC, Olivero OA.

Curr Protoc Toxicol. 2015 Nov 2;66:3.13.1-8. doi: 10.1002/0471140856.tx0313s66.

4.

Optimization of drug-like properties of nonsteroidal glucocorticoid mimetics and identification of a clinical candidate.

Harcken C, Riether D, Liu P, Razavi H, Patel U, Lee T, Bosanac T, Ward Y, Ralph M, Chen Z, Souza D, Nelson RM, Kukulka A, Fadra-Khan TN, Zuvela-Jelaska L, Patel M, Thomson DS, Nabozny GH.

ACS Med Chem Lett. 2014 Nov 20;5(12):1318-23. doi: 10.1021/ml500387y. eCollection 2014 Dec 11.

5.

Role of nucleotide excision repair and p53 in zidovudine (AZT)-induced centrosomal deregulation.

Momot D, Nostrand TA, John K, Ward Y, Steinberg SM, Liewehr DJ, Poirier MC, Olivero OA.

Environ Mol Mutagen. 2014 Dec;55(9):719-26. doi: 10.1002/em.21889. Epub 2014 Jul 30.

PMID:
25073973
6.

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.

Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J, Ward Y, Wu LG, Liu ZG.

Nat Cell Biol. 2014 Jan;16(1):55-65. doi: 10.1038/ncb2883. Epub 2013 Dec 8. Erratum in: Nat Cell Biol. 2014 Feb;16(2):200.

PMID:
24316671
7.

Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement.

Moss N, Xiong Z, Burke M, Cogan D, Gao DA, Haverty K, Heim-Riether A, Hickey ER, Nagaraja R, Netherton M, O'Shea K, Ramsden P, Schwartz R, Shih DT, Ward Y, Young E, Zhang Q.

Bioorg Med Chem Lett. 2012 Dec 1;22(23):7189-93. doi: 10.1016/j.bmcl.2012.09.054. Epub 2012 Oct 2.

PMID:
23084902
8.

TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation.

Casey OM, Fang L, Hynes PG, Abou-Kheir WG, Martin PL, Tillman HS, Petrovics G, Awwad HO, Ward Y, Lake R, Zhang L, Kelly K.

PLoS One. 2012;7(7):e41668. doi: 10.1371/journal.pone.0041668. Epub 2012 Jul 30.

9.

CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model.

Ward Y, Lake R, Martin PL, Killian K, Salerno P, Wang T, Meltzer P, Merino M, Cheng SY, Santoro M, Garcia-Rostan G, Kelly K.

Oncogene. 2013 May 30;32(22):2726-38. doi: 10.1038/onc.2012.301. Epub 2012 Jul 16.

PMID:
22797060
10.

Histone deacetylase inhibitors influence chemotherapy transport by modulating expression and trafficking of a common polymorphic variant of the ABCG2 efflux transporter.

Basseville A, Tamaki A, Ierano C, Trostel S, Ward Y, Robey RW, Hegde RS, Bates SE.

Cancer Res. 2012 Jul 15;72(14):3642-51. doi: 10.1158/0008-5472.CAN-11-2008. Epub 2012 Apr 3.

11.

LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells.

Ward Y, Lake R, Yin JJ, Heger CD, Raffeld M, Goldsmith PK, Merino M, Kelly K.

Cancer Res. 2011 Dec 1;71(23):7301-11. doi: 10.1158/0008-5472.CAN-11-2381. Epub 2011 Oct 6.

12.

Phosphorylation of paxillin at threonine 538 by PKCdelta regulates LFA1-mediated adhesion of lymphoid cells.

Romanova LY, Holmes G, Bahte SK, Kovalchuk AL, Nelson PJ, Ward Y, Gueler F, Mushinski JF.

J Cell Sci. 2010 May 1;123(Pt 9):1567-77. doi: 10.1242/jcs.060996. Epub 2010 Apr 13.

13.

Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2.

Polgar O, Ierano C, Tamaki A, Stanley B, Ward Y, Xia D, Tarasova N, Robey RW, Bates SE.

Biochemistry. 2010 Mar 16;49(10):2235-45. doi: 10.1021/bi902085q.

14.

Clinical outcome in children with recurrent neuroblastoma treated with ABT-751 and effect of ABT-751 on proliferation of neuroblastoma cell lines and on tubulin polymerization in vitro.

Meany HJ, Sackett DL, Maris JM, Ward Y, Krivoshik A, Cohn SL, Steinberg SM, Balis FM, Fox E.

Pediatr Blood Cancer. 2010 Jan;54(1):47-54. doi: 10.1002/pbc.22267.

15.

Centrosome amplification induced by the antiretroviral nucleoside reverse transcriptase inhibitors lamivudine, stavudine, and didanosine.

Yu M, Ward Y, Poirier MC, Olivero OA.

Environ Mol Mutagen. 2009 Oct;50(8):718-24. doi: 10.1002/em.20509.

16.

Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells.

Borojerdi JP, Ming J, Cooch C, Ward Y, Semino-Mora C, Yu M, Braun HM, Taylor BJ, Poirier MC, Olivero OA.

Mutat Res. 2009 Jun 1;665(1-2):67-74. doi: 10.1016/j.mrfmmm.2009.03.004. Epub 2009 Mar 24.

17.

Arginine 383 is a crucial residue in ABCG2 biogenesis.

Polgar O, Ediriwickrema LS, Robey RW, Sharma A, Hegde RS, Li Y, Xia D, Ward Y, Dean M, Ozvegy-Laczka C, Sarkadi B, Bates SE.

Biochim Biophys Acta. 2009 Jul;1788(7):1434-43. doi: 10.1016/j.bbamem.2009.04.016. Epub 2009 May 3.

18.

Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response.

Aprelikova O, Pandolfi S, Tackett S, Ferreira M, Salnikow K, Ward Y, Risinger JI, Barrett JC, Niederhuber J.

Cancer Res. 2009 Jan 15;69(2):616-24. doi: 10.1158/0008-5472.CAN-08-0811.

19.

TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.

Oberst MD, Beberman SJ, Zhao L, Yin JJ, Ward Y, Kelly K.

BMC Cancer. 2008 Jul 2;8:189. doi: 10.1186/1471-2407-8-189.

20.
21.

ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion.

Ha VL, Bharti S, Inoue H, Vass WC, Campa F, Nie Z, de Gramont A, Ward Y, Randazzo PA.

J Biol Chem. 2008 May 30;283(22):14915-26. doi: 10.1074/jbc.M709717200. Epub 2008 Apr 8.

22.

The discovery of carboline analogs as potent MAPKAP-K2 inhibitors.

Wu JP, Wang J, Abeywardane A, Andersen D, Emmanuel M, Gautschi E, Goldberg DR, Kashem MA, Lukas S, Mao W, Martin L, Morwick T, Moss N, Pargellis C, Patel UR, Patnaude L, Peet GW, Skow D, Snow RJ, Ward Y, Werneburg B, White A.

Bioorg Med Chem Lett. 2007 Aug 15;17(16):4664-9. Epub 2007 Jun 7.

PMID:
17576063
23.

Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors.

Bekkali Y, Thomson DS, Betageri R, Emmanuel MJ, Hao MH, Hickey E, Liu W, Patel U, Ward YD, Young ER, Nelson R, Kukulka A, Brown ML, Crane K, White D, Freeman DM, Labadia ME, Wildeson J, Spero DM.

Bioorg Med Chem Lett. 2007 May 1;17(9):2465-9. Epub 2007 Feb 23.

PMID:
17379516
24.

Improved antibacterial host defense and altered peripheral granulocyte homeostasis in mice lacking the adhesion class G protein receptor CD97.

Wang T, Tian L, Haino M, Gao JL, Lake R, Ward Y, Wang H, Siebenlist U, Murphy PM, Kelly K.

Infect Immun. 2007 Mar;75(3):1144-53. Epub 2006 Dec 11.

25.

Structure-function studies of the G-domain from human gem, a novel small G-protein.

Opatowsky Y, Sasson Y, Shaked I, Ward Y, Chomsky-Hecht O, Litvak Y, Selinger Z, Kelly K, Hirsch JA.

FEBS Lett. 2006 Oct 30;580(25):5959-64. Epub 2006 Oct 6.

26.

Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells.

Kuznetsova SA, Issa P, Perruccio EM, Zeng B, Sipes JM, Ward Y, Seyfried NT, Fielder HL, Day AJ, Wight TN, Roberts DD.

J Cell Sci. 2006 Nov 1;119(Pt 21):4499-509. Epub 2006 Oct 17.

27.

Gem protein signaling and regulation.

Ward Y, Kelly K.

Methods Enzymol. 2006;407:468-83.

PMID:
16757346
28.

Mutational studies of G553 in TM5 of ABCG2: a residue potentially involved in dimerization.

Polgar O, Ozvegy-Laczka C, Robey RW, Morisaki K, Okada M, Tamaki A, Koblos G, Elkind NB, Ward Y, Dean M, Sarkadi B, Bates SE.

Biochemistry. 2006 Apr 25;45(16):5251-60.

29.

Expression of FasL in squamous cell carcinomas of the cervix and cervical intraepithelial neoplasia and its role in tumor escape mechanism.

Ibrahim R, Frederickson H, Parr A, Ward Y, Moncur J, Khleif SN.

Cancer. 2006 Mar 1;106(5):1065-77.

30.

Human CD69 associates with an N-terminal fragment of calreticulin at the cell surface.

Vance BA, Harley PH, Backlund PS, Ward Y, Phelps TL, Gress RE.

Arch Biochem Biophys. 2005 Jun 1;438(1):11-20.

PMID:
15893733
31.

Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK.

Oh J, Seo DW, Diaz T, Wei B, Ward Y, Ray JM, Morioka Y, Shi S, Kitayama H, Takahashi C, Noda M, Stetler-Stevenson WG.

Cancer Res. 2004 Dec 15;64(24):9062-9.

32.

CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells.

Wang T, Ward Y, Tian L, Lake R, Guedez L, Stetler-Stevenson WG, Kelly K.

Blood. 2005 Apr 1;105(7):2836-44. Epub 2004 Dec 2.

33.

Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh.

Chen Y, Knezevic V, Ervin V, Hutson R, Ward Y, Mackem S.

Development. 2004 May;131(10):2339-47. Epub 2004 Apr 21.

34.
35.

Tumor expression of 4-1BB ligand sustains tumor lytic T cells.

Zhang H, Merchant MS, Chua KS, Khanna C, Helman LJ, Telford B, Ward Y, Summers J, Toretsky J, Thomas EK, June CH, Mackall CL.

Cancer Biol Ther. 2003 Sep-Oct;2(5):579-86.

PMID:
14614331
36.

Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors.

Ward YD, Thomson DS, Frye LL, Cywin CL, Morwick T, Emmanuel MJ, Zindell R, McNeil D, Bekkali Y, Girardot M, Hrapchak M, DeTuri M, Crane K, White D, Pav S, Wang Y, Hao MH, Grygon CA, Labadia ME, Freeman DM, Davidson W, Hopkins JL, Brown ML, Spero DM.

J Med Chem. 2002 Dec 5;45(25):5471-82. Erratum in: J Med Chem. 2003 Feb 27;46(5):882.. Giradot Marc [corrected to Girardot Marc].

PMID:
12459015
37.

Revelation of a cryptic major histocompatibility complex class II-restricted tumor epitope in a novel RNA-processing enzyme.

Topalian SL, Gonzales MI, Ward Y, Wang X, Wang RF.

Cancer Res. 2002 Oct 1;62(19):5505-9.

38.

The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway.

Ward Y, Yap SF, Ravichandran V, Matsumura F, Ito M, Spinelli B, Kelly K.

J Cell Biol. 2002 Apr 15;157(2):291-302. Epub 2002 Apr 15.

39.

Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism.

Poruchynsky MS, Giannakakou P, Ward Y, Bulinski JC, Telford WG, Robey RW, Fojo T.

Biochem Pharmacol. 2001 Dec 1;62(11):1469-80.

PMID:
11728383
41.

Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors.

Topalian SL, Kaneko S, Gonzales MI, Bond GL, Ward Y, Manley JL.

Mol Cell Biol. 2001 Aug;21(16):5614-23.

42.

The Gem GTP-binding protein promotes morphological differentiation in neuroblastoma.

Leone A, Mitsiades N, Ward Y, Spinelli B, Poulaki V, Tsokos M, Kelly K.

Oncogene. 2001 May 31;20(25):3217-25.

43.

Microstructural analysis of silicon carbide monofilaments.

Shatwell RA, Dyos KL, Prentice C, Ward Y, Young RJ.

J Microsc. 2001 Feb;201(2):179-188.

44.

p53 is associated with cellular microtubules and is transported to the nucleus by dynein.

Giannakakou P, Sackett DL, Ward Y, Webster KR, Blagosklonny MV, Fojo T.

Nat Cell Biol. 2000 Oct;2(10):709-17.

PMID:
11025661
45.

Coexpression of receptors for adrenomedullin, calcitonin gene-related peptide, and amylin in pancreatic beta-cells.

Martínez A, Kapas S, Miller MJ, Ward Y, Cuttitta F.

Endocrinology. 2000 Jan;141(1):406-11.

PMID:
10614663
46.

Distinct but dispensable N-glycosylation of human CD69 proteins.

Vance BA, Bennett MJ, Ward Y, Gress RG, Kearse KP.

Arch Biochem Biophys. 1999 Aug 15;368(2):214-20.

PMID:
10441371
47.

The womanly garb of Queen Victoria's early motherhood, 1840-42.

Ward YM.

Womens Hist Rev. 1999;8(2):277-94. No abstract available.

PMID:
22619794
48.

Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1.

Ward Y, Gupta S, Jensen P, Wartmann M, Davis RJ, Kelly K.

Nature. 1994 Feb 17;367(6464):651-4.

PMID:
8107850

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