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Study supporting eFONA cannula approach: on point?

Ward PA.

Anaesthesia. 2020 Jan;75(1):129-130. doi: 10.1111/anae.14883. No abstract available.


Disruption of Neutrophil Extracellular Traps (NETs) Links Mechanical Strain to Post-traumatic Inflammation.

Agarwal S, Loder SJ, Cholok D, Li J, Bian G, Yalavarthi S, Li S, Carson WF, Hwang C, Marini S, Pagani C, Edwards N, Delano MJ, Standiford TJ, Knight JS, Kunkel SL, Mishina Y, Ward PA, Levi B.

Front Immunol. 2019 Oct 24;10:2148. doi: 10.3389/fimmu.2019.02148. eCollection 2019.


A clinical survey of mosaic single nucleotide variants in disease-causing genes detected by exome sequencing.

Cao Y, Tokita MJ, Chen ES, Ghosh R, Chen T, Feng Y, Gorman E, Gibellini F, Ward PA, Braxton A, Wang X, Meng L, Xiao R, Bi W, Xia F, Eng CM, Yang Y, Gambin T, Shaw C, Liu P, Stankiewicz P.

Genome Med. 2019 Jul 26;11(1):48. doi: 10.1186/s13073-019-0658-2.


Airway management research and the need for consensus.

Ward PA, Irwin MG.

Anaesthesia. 2019 Jul;74(7):942. doi: 10.1111/anae.14624. No abstract available.


Introducing new emergency front-of-neck access equipment into clinical practice.

Ward PA.

Anaesthesia. 2019 Jun;74(6):814. doi: 10.1111/anae.14652. No abstract available.


A toolkit for genetics providers in follow-up of patients with non-diagnostic exome sequencing.

Zastrow DB, Kohler JN, Bonner D, Reuter CM, Fernandez L, Grove ME, Fisk DG; Undiagnosed Diseases Network, Yang Y, Eng CM, Ward PA, Bick D, Worthey EA, Fisher PG, Ashley EA, Bernstein JA, Wheeler MT.

J Genet Couns. 2019 Apr;28(2):213-228. doi: 10.1002/jgc4.1119. Erratum in: J Genet Couns. 2019 May 21;:.


Potential problems with titrating total intravenous anaesthesia.

Ward PA.

Anaesthesia. 2019 May;74(5):676. doi: 10.1111/anae.14626. No abstract available.


Polythiophene Doping of the Cu-Based Metal-Organic Framework (MOF) HKUST-1 Using Innate MOF-Initiated Oxidative Polymerization.

Marshall N, James W, Fulmer J, Crittenden S, Thompson AB, Ward PA, Rowe GT.

Inorg Chem. 2019 May 6;58(9):5561-5575. doi: 10.1021/acs.inorgchem.8b03465. Epub 2019 Apr 5.


New strategies for treatment of infectious sepsis.

Ward PA, Fattahi F.

J Leukoc Biol. 2019 Jul;106(1):187-192. doi: 10.1002/JLB.4MIR1118-425R. Epub 2019 Mar 1. Review.


GM-CSF Administration Improves Defects in Innate Immunity and Sepsis Survival in Obese Diabetic Mice.

Frydrych LM, Bian G, Fattahi F, Morris SB, O'Rourke RW, Lumeng CN, Kunkel SL, Ward PA, Delano MJ.

J Immunol. 2019 Feb 1;202(3):931-942. doi: 10.4049/jimmunol.1800713. Epub 2018 Dec 21.


Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis.

Fattahi F, Russell MW, Malan EA, Parlett M, Abe E, Zetoune FS, Ward PA.

Biomed Res Int. 2018 Sep 30;2018:4302726. doi: 10.1155/2018/4302726. eCollection 2018.


Clinical exome sequencing for fetuses with ultrasound abnormalities and a suspected Mendelian disorder.

Normand EA, Braxton A, Nassef S, Ward PA, Vetrini F, He W, Patel V, Qu C, Westerfield LE, Stover S, Dharmadhikari AV, Muzny DM, Gibbs RA, Dai H, Meng L, Wang X, Xiao R, Liu P, Bi W, Xia F, Walkiewicz M, Van den Veyver IB, Eng CM, Yang Y.

Genome Med. 2018 Sep 28;10(1):74. doi: 10.1186/s13073-018-0582-x.


Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality.

Frydrych LM, Bian G, O'Lone DE, Ward PA, Delano MJ.

J Leukoc Biol. 2018 Sep;104(3):525-534. doi: 10.1002/JLB.5VMR0118-021RR. Epub 2018 Aug 1. Review.


Role of complement C5a and histones in septic cardiomyopathy.

Fattahi F, Frydrych LM, Bian G, Kalbitz M, Herron TJ, Malan EA, Delano MJ, Ward PA.

Mol Immunol. 2018 Oct;102:32-41. doi: 10.1016/j.molimm.2018.06.006. Epub 2018 Jun 18. Review.


Innate immune responses to trauma.

Huber-Lang M, Lambris JD, Ward PA.

Nat Immunol. 2018 Apr;19(4):327-341. doi: 10.1038/s41590-018-0064-8. Epub 2018 Mar 5. Review.


Positional Differences in Running and Nonrunning Activities During Elite American Football Training.

Ward PA, Ramsden S, Coutts AJ, Hulton AT, Drust B.

J Strength Cond Res. 2018 Jul;32(7):2072-2084. doi: 10.1519/JSC.0000000000002294.


Diabetes and Sepsis: Risk, Recurrence, and Ruination.

Frydrych LM, Fattahi F, He K, Ward PA, Delano MJ.

Front Endocrinol (Lausanne). 2017 Oct 30;8:271. doi: 10.3389/fendo.2017.00271. eCollection 2017. Review.


Positive predictive value estimates for cell-free noninvasive prenatal screening from data of a large referral genetic diagnostic laboratory.

Petersen AK, Cheung SW, Smith JL, Bi W, Ward PA, Peacock S, Braxton A, Van Den Veyver IB, Breman AM.

Am J Obstet Gynecol. 2017 Dec;217(6):691.e1-691.e6. doi: 10.1016/j.ajog.2017.10.005. Epub 2017 Oct 13.


Consensus on ethics in airway research - a reply.

Irwin MG, Ward PA.

Anaesthesia. 2017 Oct;72(10):1278-1279. doi: 10.1111/anae.14021. No abstract available.


Understanding Immunosuppression after Sepsis.

Fattahi F, Ward PA.

Immunity. 2017 Jul 18;47(1):3-5. doi: 10.1016/j.immuni.2017.07.007.


Erratum to: Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features.

Zhang J, Gambin T, Yuan B, Szafranski P, Rosenfeld JA, Balwi MA, Alswaid A, Al-Gazali L, Shamsi AMA, Komara M, Ali BR, Roeder E, McAuley L, Roy DS, Manchester DK, Magoulas P, King LE, Hannig V, Bonneau D, Denommé-Pichon AS, Charif M, Besnard T, Bézieau S, Cogné B, Andrieux J, Zhu W, He W, Vetrini F, Ward PA, Cheung SW, Bi W, Eng CM, Lupski JR, Yang Y, Patel A, Lalani SR, Xia F, Stankiewicz P.

Hum Genet. 2017 Aug;136(8):1009-1011. doi: 10.1007/s00439-017-1828-1. No abstract available.


Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction.

Fattahi F, Kalbitz M, Malan EA, Abe E, Jajou L, Huber-Lang MS, Bosmann M, Russell MW, Zetoune FS, Ward PA.

FASEB J. 2017 Sep;31(9):4129-4139. doi: 10.1096/fj.201700140R. Epub 2017 Jun 1.


Difficult airway research options and ethical consensus - a reply.

Irwin MG, Ward PA.

Anaesthesia. 2017 Apr;72(4):542-543. doi: 10.1111/anae.13859. No abstract available.


Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features.

Zhang J, Gambin T, Yuan B, Szafranski P, Rosenfeld JA, Balwi MA, Alswaid A, Al-Gazali L, Shamsi AMA, Komara M, Ali BR, Roeder E, McAuley L, Roy DS, Manchester DK, Magoulas P, King LE, Hannig V, Bonneau D, Denommé-Pichon AS, Charif M, Besnard T, Bézieau S, Cogné B, Andrieux J, Zhu W, He W, Vetrini F, Ward PA, Cheung SW, Bi W, Eng CM, Lupski JR, Yang Y, Patel A, Lalani SR, Xia F, Stankiewicz P.

Hum Genet. 2017 Apr;136(4):377-386. doi: 10.1007/s00439-017-1763-1. Epub 2017 Mar 1. Erratum in: Hum Genet. 2017 Jun 28;:.


Selective Biological Responses of Phagocytes and Lungs to Purified Histones.

Fattahi F, Grailer JJ, Lu H, Dick RS, Parlett M, Zetoune FS, Nuñez G, Ward PA.

J Innate Immun. 2017;9(3):300-317. doi: 10.1159/000452951. Epub 2017 Feb 8.


Complement and sepsis-induced heart dysfunction.

Fattahi F, Ward PA.

Mol Immunol. 2017 Apr;84:57-64. doi: 10.1016/j.molimm.2016.11.012. Epub 2016 Dec 5. Review.


Editorial: Blockade of PD-1 and PD-L1 restores defective innate immune responses in leukocytes from septic humans.

Ward PA, Fattahi F.

J Leukoc Biol. 2016 Dec;100(6):1229-1231. No abstract available.


Investigation of hydrogen induced fluorescence in C60 and its potential use in luminescence down shifting applications.

Teprovich JA, Washington AL, Dixon J, Ward PA, Christian JH, Peters B, Zhou J, Giri S, Sharp DN, Velten JA, Compton RN, Jena P, Zidan R.

Nanoscale. 2016 Nov 10;8(44):18760-18770.


The immune system's role in sepsis progression, resolution, and long-term outcome.

Delano MJ, Ward PA.

Immunol Rev. 2016 Nov;274(1):330-353. doi: 10.1111/imr.12499. Review.


Man vs. manikin revisited - the ethical boundaries of simulating difficult airways in patients.

Ward PA, Irwin MG.

Anaesthesia. 2016 Dec;71(12):1399-1403. doi: 10.1111/anae.13526. Epub 2016 Sep 27. No abstract available.


Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis.

Kalbitz M, Fattahi F, Grailer JJ, Jajou L, Malan EA, Zetoune FS, Huber-Lang M, Russell MW, Ward PA.

FASEB J. 2016 Dec;30(12):3997-4006. Epub 2016 Aug 19.


Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro.

Kalbitz M, Fattahi F, Herron TJ, Grailer JJ, Jajou L, Lu H, Huber-Lang M, Zetoune FS, Sarma JV, Day SM, Russell MW, Jalife J, Ward PA.

J Immunol. 2016 Sep 15;197(6):2353-61. doi: 10.4049/jimmunol.1600091. Epub 2016 Aug 12.


Bidirectional Crosstalk between C5a Receptors and the NLRP3 Inflammasome in Macrophages and Monocytes.

Haggadone MD, Grailer JJ, Fattahi F, Zetoune FS, Ward PA.

Mediators Inflamm. 2016;2016:1340156. doi: 10.1155/2016/1340156. Epub 2016 Jun 7.


Complement: an unfinished symphony.

Ward PA.

Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F66-7. doi: 10.1152/ajprenal.00250.2016. Epub 2016 May 4. No abstract available.


In Sepsis, Complement Is Alive and Well.

Ward PA.

Crit Care Med. 2016 May;44(5):1026-7. doi: 10.1097/CCM.0000000000001593. No abstract available.


New Insights into Molecular Mechanisms of Immune Complex-Induced Injury in Lung.

Ward PA, Fattahi F, Bosmann M.

Front Immunol. 2016 Mar 9;7:86. doi: 10.3389/fimmu.2016.00086. eCollection 2016. Review.


Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome.

Zhang Y, Li X, Grailer JJ, Wang N, Wang M, Yao J, Zhong R, Gao GF, Ward PA, Tan DX, Li X.

J Pineal Res. 2016 May;60(4):405-14. doi: 10.1111/jpi.12322. Epub 2016 Mar 9.


Sepsis-induced immune dysfunction: can immune therapies reduce mortality?

Delano MJ, Ward PA.

J Clin Invest. 2016 Jan;126(1):23-31. doi: 10.1172/JCI82224. Epub 2016 Jan 4. Review.


Experimental Malaria in Pregnancy Induces Neurocognitive Injury in Uninfected Offspring via a C5a-C5a Receptor Dependent Pathway.

McDonald CR, Cahill LS, Ho KT, Yang J, Kim H, Silver KL, Ward PA, Mount HT, Liles WC, Sled JG, Kain KC.

PLoS Pathog. 2015 Sep 24;11(9):e1005140. doi: 10.1371/journal.ppat.1005140. eCollection 2015 Sep.


Anti-inflammatory interventions-what has worked, not worked, and what may work in the future.

Fattahi F, Ward PA.

Transl Res. 2016 Jan;167(1):1-6. doi: 10.1016/j.trsl.2015.08.003. Epub 2015 Aug 14. No abstract available.


The molecular fingerprint of lung inflammation after blunt chest trauma.

Ehrnthaller C, Flierl M, Perl M, Denk S, Unnewehr H, Ward PA, Radermacher P, Ignatius A, Gebhard F, Chinnaiyan A, Huber-Lang M.

Eur J Med Res. 2015 Aug 25;20:70. doi: 10.1186/s40001-015-0164-y.


NAP5: aware of the limitations.

Ward PA.

Br J Anaesth. 2015 Sep;115(3):476. doi: 10.1093/bja/aev269. No abstract available.


Resolvins on the way to resolution.

Ward PA.

J Exp Med. 2015 Jul 27;212(8):1142. doi: 10.1084/jem.2128insight4. No abstract available.


Therapeutic targeting of acute lung injury and acute respiratory distress syndrome.

Standiford TJ, Ward PA.

Transl Res. 2016 Jan;167(1):183-91. doi: 10.1016/j.trsl.2015.04.015. Epub 2015 May 5. Review.


Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin.

Russkamp NF, Ruemmler R, Roewe J, Moore BB, Ward PA, Bosmann M.

FASEB J. 2015 Sep;29(9):3762-72. doi: 10.1096/fj.15-271635. Epub 2015 May 21.


Difficult decisions.

Ward PA.

Br J Anaesth. 2015 Apr;114(4):706. doi: 10.1093/bja/aev052. No abstract available.


Role of extracellular histones in the cardiomyopathy of sepsis.

Kalbitz M, Grailer JJ, Fattahi F, Jajou L, Herron TJ, Campbell KF, Zetoune FS, Bosmann M, Sarma JV, Huber-Lang M, Gebhard F, Loaiza R, Valdivia HH, Jalife J, Russell MW, Ward PA.

FASEB J. 2015 May;29(5):2185-93. doi: 10.1096/fj.14-268730. Epub 2015 Feb 13.


Organ distribution of histones after intravenous infusion of FITC histones or after sepsis.

Fattahi F, Grailer JJ, Jajou L, Zetoune FS, Andjelkovic AV, Ward PA.

Immunol Res. 2015 Mar;61(3):177-86. doi: 10.1007/s12026-015-8628-2.


Influence of lipopolysaccharide-binding protein on pulmonary inflammation in gram-negative pneumonia.

Taddonio MA, Dolgachev V, Bosmann M, Ward PA, Su G, Wang SC, Hemmila MR.

Shock. 2015 Jun;43(6):612-9. doi: 10.1097/SHK.0000000000000349.


Cutting edge: critical role for C5aRs in the development of septic lymphopenia in mice.

Grailer JJ, Fattahi F, Dick RS, Zetoune FS, Ward PA.

J Immunol. 2015 Feb 1;194(3):868-72. doi: 10.4049/jimmunol.1401193. Epub 2014 Dec 24.

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