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Items: 1 to 50 of 52

1.

Identification of Serine-875 as an Inhibitory Phosphorylation Site in the Calcium-Sensing Receptor.

Binmahfouz LS, Centeno PP, Conigrave AD, Ward DT.

Mol Pharmacol. 2019 Jun 12. pii: mol.119.116178. doi: 10.1124/mol.119.116178. [Epub ahead of print]

2.

Increased conditional risk of recurring complications with contralateral total hip arthroplasty surgery.

Roberts HJ, Tsay EL, Grace TR, Vail TP, Ward DT.

Bone Joint J. 2019 Jun;101-B(6_Supple_B):77-83. doi: 10.1302/0301-620X.101B6.BJJ-2018-1488.R1.

PMID:
31146565
3.

Routine Patellar Resurfacing During Total Knee Arthroplasty Is Not Cost-Effective in Patients Without Patellar Arthritis.

Zmistowski BM, Fillingham YA, Salmons HI, Ward DT, Good RP, Lonner JH.

J Arthroplasty. 2019 Apr 26. pii: S0883-5403(19)30408-5. doi: 10.1016/j.arth.2019.04.040. [Epub ahead of print]

PMID:
31104838
4.

Treatment of Autosomal Dominant Hypocalcemia Type 1 with the Calcilytic NPSP795 (SHP635).

Roberts MS, Gafni RI, Brillante B, Guthrie LC, Streit J, Gash D, Gelb J, Krusinska E, Brennan SC, Schepelmann M, Riccardi D, Bin Khayat ME, Ward DT, Nemeth EF, Rosskamp R, Collins MT.

J Bone Miner Res. 2019 May 7. doi: 10.1002/jbmr.3747. [Epub ahead of print]

PMID:
31063613
5.

Hip Fractures and the Bundle: A Cost Analysis of Patients Undergoing Hip Arthroplasty for Femoral Neck Fracture vs Degenerative Joint Disease.

Grace TR, Patterson JT, Tangtiphaiboontana J, Krogue JD, Vail TP, Ward DT.

J Arthroplasty. 2018 Jun;33(6):1681-1685. doi: 10.1016/j.arth.2018.01.071. Epub 2018 Feb 5.

PMID:
29506928
6.

The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure.

Schepelmann M, Yarova PL, Lopez-Fernandez I, Davies TS, Brennan SC, Edwards PJ, Aggarwal A, Graça J, Rietdorf K, Matchkov V, Fenton RA, Chang W, Krssak M, Stewart A, Broadley KJ, Ward DT, Price SA, Edwards DH, Kemp PJ, Riccardi D.

Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C193-204. doi: 10.1152/ajpcell.00248.2015. Epub 2015 Nov 4.

7.

Complications of Morbid Obesity in Total Joint Arthroplasty: Risk Stratification Based on BMI.

Ward DT, Metz LN, Horst PK, Kim HT, Kuo AC.

J Arthroplasty. 2015 Sep;30(9 Suppl):42-6. doi: 10.1016/j.arth.2015.03.045. Epub 2015 Jun 3.

PMID:
26117070
8.

Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma.

Yarova PL, Stewart AL, Sathish V, Britt RD Jr, Thompson MA, P Lowe AP, Freeman M, Aravamudan B, Kita H, Brennan SC, Schepelmann M, Davies T, Yung S, Cholisoh Z, Kidd EJ, Ford WR, Broadley KJ, Rietdorf K, Chang W, Bin Khayat ME, Ward DT, Corrigan CJ, T Ward JP, Kemp PJ, Pabelick CM, Prakash YS, Riccardi D.

Sci Transl Med. 2015 Apr 22;7(284):284ra60. doi: 10.1126/scitranslmed.aaa0282. Epub 2015 Apr 22.

9.

Pathophysiologic Changes in Extracellular pH Modulate Parathyroid Calcium-Sensing Receptor Activity and Secretion via a Histidine-Independent Mechanism.

Campion KL, McCormick WD, Warwicker J, Khayat ME, Atkinson-Dell R, Steward MC, Delbridge LW, Mun HC, Conigrave AD, Ward DT.

J Am Soc Nephrol. 2015 Sep;26(9):2163-71. doi: 10.1681/ASN.2014070653. Epub 2015 Jan 2.

10.

The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.

11.

The inhibitory effect of simvastatin and aspirin on histamine responsiveness in human vascular endothelial cells.

Absi M, Bruce JI, Ward DT.

Am J Physiol Cell Physiol. 2014 Apr 1;306(7):C679-86. doi: 10.1152/ajpcell.00304.2013. Epub 2014 Jan 29.

12.

Calcium-sensing receptor (CaSR): pharmacological properties and signaling pathways.

Conigrave AD, Ward DT.

Best Pract Res Clin Endocrinol Metab. 2013 Jun;27(3):315-31. doi: 10.1016/j.beem.2013.05.010. Epub 2013 Jun 17. Review.

PMID:
23856262
13.

Risk factors for periprosthetic joint infection following primary total hip arthroplasty: a case control study.

Bozic KJ, Ward DT, Lau EC, Chan V, Wetters NG, Naziri Q, Odum S, Fehring TK, Mont MA, Gioe TJ, Della Valle CJ.

J Arthroplasty. 2014 Jan;29(1):154-6. doi: 10.1016/j.arth.2013.04.015. Epub 2013 May 20.

PMID:
23702271
14.

Molecular and clinical analysis of a neonatal severe hyperparathyroidism case caused by a stop mutation in the calcium-sensing receptor extracellular domain representing in effect a human 'knockout'.

Ward DT, Mughal MZ, Ranieri M, Dvorak-Ewell MM, Valenti G, Riccardi D.

Eur J Endocrinol. 2013 Jun 1;169(1):K1-7. doi: 10.1530/EJE-13-0094. Print 2013 Jul.

PMID:
23612447
15.

Short communication: urea transporter protein UT-B in the bovine parotid gland.

Dix L, Ward DT, Stewart GS.

J Dairy Sci. 2013 Mar;96(3):1685-90. doi: 10.3168/jds.2012-6230. Epub 2013 Jan 26.

16.

Increased endothelin-1 responsiveness in human coronary artery smooth muscle cells exposed to 1,25-dihydroxyvitamin D(3).

Absi M, Ward DT.

Am J Physiol Cell Physiol. 2013 Apr 1;304(7):C666-72. doi: 10.1152/ajpcell.00349.2012. Epub 2013 Jan 23.

17.

New concepts in calcium-sensing receptor pharmacology and signalling.

Ward DT, Riccardi D.

Br J Pharmacol. 2012 Jan;165(1):35-48. doi: 10.1111/j.1476-5381.2011.01511.x. Review.

18.

A novel mutation of the primary protein kinase C phosphorylation site in the calcium-sensing receptor causes autosomal dominant hypocalcemia.

Lazarus S, Pretorius CJ, Khafagi F, Campion KL, Brennan SC, Conigrave AD, Brown EM, Ward DT.

Eur J Endocrinol. 2011 Mar;164(3):429-35. doi: 10.1530/EJE-10-0907. Epub 2010 Dec 6.

PMID:
21135065
19.

Cost and effectiveness of postoperative fever diagnostic evaluation in total joint arthroplasty patients.

Ward DT, Hansen EN, Takemoto SK, Bozic KJ.

J Arthroplasty. 2010 Sep;25(6 Suppl):43-8. doi: 10.1016/j.arth.2010.03.016. Epub 2010 May 10.

PMID:
20452174
20.

Increased receptor stimulation elicits differential calcium-sensing receptor(T888) dephosphorylation.

McCormick WD, Atkinson-Dell R, Campion KL, Mun HC, Conigrave AD, Ward DT.

J Biol Chem. 2010 May 7;285(19):14170-7. doi: 10.1074/jbc.M109.071084. Epub 2010 Mar 16.

21.

Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells.

Alam MU, Kirton JP, Wilkinson FL, Towers E, Sinha S, Rouhi M, Vizard TN, Sage AP, Martin D, Ward DT, Alexander MY, Riccardi D, Canfield AE.

Cardiovasc Res. 2009 Feb 1;81(2):260-8. doi: 10.1093/cvr/cvn279. Epub 2008 Oct 13.

PMID:
18852253
22.

Extracellular calcium- and magnesium-mediated regulation of passive calcium transport across Caco-2 monolayers.

Davies SL, Gibbons CE, Steward MC, Ward DT.

Biochim Biophys Acta. 2008 Oct;1778(10):2318-24. doi: 10.1016/j.bbamem.2008.05.013. Epub 2008 Jun 4.

23.

The expression and function of Ca(2+)-sensing receptors in rat mesenteric artery; comparative studies using a model of type II diabetes.

Weston AH, Absi M, Harno E, Geraghty AR, Ward DT, Ruat M, Dodd RH, Dauban P, Edwards G.

Br J Pharmacol. 2008 Jun;154(3):652-62. doi: 10.1038/bjp.2008.108. Epub 2008 Apr 14.

24.

Calcium-sensing receptor antagonism or lithium treatment ameliorates aminoglycoside-induced cell death in renal epithelial cells.

Gibbons CE, Maldonado-Pérez D, Shah AN, Riccardi D, Ward DT.

Biochim Biophys Acta. 2008 Mar;1782(3):188-95. doi: 10.1016/j.bbadis.2008.01.003. Epub 2008 Jan 26.

25.

Evidence for the presence of GPRC6A receptors in rat mesenteric arteries.

Harno E, Edwards G, Geraghty AR, Ward DT, Dodd RH, Dauban P, Faure H, Ruat M, Weston AH.

Cell Calcium. 2008 Aug;44(2):210-9. doi: 10.1016/j.ceca.2007.11.011. Epub 2008 Jan 24.

PMID:
18221783
26.
27.

Ca2+-sensing receptor induces Rho kinase-mediated actin stress fiber assembly and altered cell morphology, but not in response to aromatic amino acids.

Davies SL, Gibbons CE, Vizard T, Ward DT.

Am J Physiol Cell Physiol. 2006 Jun;290(6):C1543-51. Epub 2006 Jan 11.

28.

A massive intra-abdominal lipomatous neoplasm arising from the bladder.

Ward DT, Swiecki CW, Peoples GE.

Curr Surg. 2002 May-Jun;59(3):299-300. No abstract available.

PMID:
16093151
29.

Evidence in favor of a calcium-sensing receptor in arterial endothelial cells: studies with calindol and Calhex 231.

Weston AH, Absi M, Ward DT, Ohanian J, Dodd RH, Dauban P, Petrel C, Ruat M, Edwards G.

Circ Res. 2005 Aug 19;97(4):391-8. Epub 2005 Jul 21.

PMID:
16037572
30.

Altered expression of iron transport proteins in streptozotocin-induced diabetic rat kidney.

Ward DT, Hamilton K, Burnand R, Smith CP, Tomlinson DR, Riccardi D.

Biochim Biophys Acta. 2005 Apr 15;1740(1):79-84. Epub 2005 Feb 23.

31.

Aminoglycosides induce acute cell signaling and chronic cell death in renal cells that express the calcium-sensing receptor.

Ward DT, Maldonado-Pérez D, Hollins L, Riccardi D.

J Am Soc Nephrol. 2005 May;16(5):1236-44. Epub 2005 Mar 30.

32.

Evidence for a functional calcium-sensing receptor that modulates myogenic tone in rat subcutaneous small arteries.

Ohanian J, Gatfield KM, Ward DT, Ohanian V.

Am J Physiol Heart Circ Physiol. 2005 Apr;288(4):H1756-62. Epub 2004 Dec 2.

33.

Differential expression of divalent metal transporter DMT1 (Slc11a2) in the spermatogenic epithelium of the developing and adult rat testis.

Griffin KP, Ward DT, Liu W, Stewart G, Morris ID, Smith CP.

Am J Physiol Cell Physiol. 2005 Jan;288(1):C176-84. Epub 2004 Sep 8.

34.

Calcium receptor-mediated intracellular signalling.

Ward DT.

Cell Calcium. 2004 Mar;35(3):217-28. Review.

PMID:
15200145
35.

Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones.

Dvorak MM, Siddiqua A, Ward DT, Carter DH, Dallas SL, Nemeth EF, Riccardi D.

Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5140-5. Epub 2004 Mar 29.

36.

Human calcium-sensing receptor can be suppressed by antisense sequences.

Maldonado-Pérez D, Breitwieser GE, Gama L, Elliott AC, Ward DT, Riccardi D.

Biochem Biophys Res Commun. 2003 Nov 21;311(3):610-7.

PMID:
14623314
37.

Calpain-mediated AQP2 proteolysis in inner medullary collecting duct.

Puliyanda DP, Ward DT, Baum MA, Hammond TG, Harris HW Jr.

Biochem Biophys Res Commun. 2003 Mar 28;303(1):52-8.

PMID:
12646165
38.

Renal physiology of the extracellular calcium-sensing receptor.

Ward DT, Riccardi D.

Pflugers Arch. 2002 Nov;445(2):169-76. Epub 2002 Sep 7. Review.

PMID:
12457237
39.

Diabetic hyperglycemia: a facilitating factor in systemic capillary leak.

Lawson S, Ward DT, Conner C, Gallagher C, Tsokos G, Shea-Donohue T.

J Surg Res. 2002 Jun 15;105(2):95-101.

PMID:
12121693
41.
42.

AQP2 is a substrate for endogenous PP2B activity within an inner medullary AKAP-signaling complex.

Jo I, Ward DT, Baum MA, Scott JD, Coghlan VM, Hammond TG, Harris HW.

Am J Physiol Renal Physiol. 2001 Nov;281(5):F958-65.

43.

Cellular localization of divalent metal transporter DMT-1 in rat kidney.

Ferguson CJ, Wareing M, Ward DT, Green R, Smith CP, Riccardi D.

Am J Physiol Renal Physiol. 2001 May;280(5):F803-14.

44.

Functional, molecular, and biochemical characterization of streptozotocin-induced diabetes.

Ward DT, Yau SK, Mee AP, Mawer EB, Miller CA, Garland HO, Riccardi D.

J Am Soc Nephrol. 2001 Apr;12(4):779-90.

45.

Dietary phosphate and parathyroid hormone alter the expression of the calcium-sensing receptor (CaR) and the Na+-dependent Pi transporter (NaPi-2) in the rat proximal tubule.

Riccardi D, Traebert M, Ward DT, Kaissling B, Biber J, Hebert SC, Murer H.

Pflugers Arch. 2000 Dec;441(2-3):379-87.

PMID:
11211126
46.

Sustained nitric oxide production via l-arginine administration ameliorates effects of intestinal ischemia-reperfusion.

Ward DT, Lawson SA, Gallagher CM, Conner WC, Shea-Donohue T.

J Surg Res. 2000 Mar;89(1):13-9.

PMID:
10720447
47.

Modulation of vasopressin-elicited water transport by trafficking of aquaporin2-containing vesicles.

Ward DT, Hammond TG, Harris HW.

Annu Rev Physiol. 1999;61:683-97. Review.

PMID:
10099706
48.

The impact of initial surgical management on outcome in young patients with differentiated thyroid cancer.

Robie DK, Dinauer CW, Tuttle RM, Ward DT, Parry R, McClellan D, Svec R, Adair C, Francis G.

J Pediatr Surg. 1998 Jul;33(7):1134-8; discussion 1139-40.

PMID:
9694109
50.

Vasopressin-elicited water and urea permeabilities are altered in IMCD in hypercalcemic rats.

Sands JM, Flores FX, Kato A, Baum MA, Brown EM, Ward DT, Hebert SC, Harris HW.

Am J Physiol. 1998 May;274(5):F978-85. doi: 10.1152/ajprenal.1998.274.5.F978.

PMID:
9612337

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