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Identification of a new inhibitor of KRAS-PDEδ interaction targeting KRAS mutant nonsmall cell lung cancer.

Leung EL, Luo LX, Li Y, Liu ZQ, Li LL, Shi DF, Xie Y, Huang M, Lu LL, Duan FG, Huang JM, Fan XX, Yuan ZW, Ding J, Yao XJ, Ward DC, Liu L.

Int J Cancer. 2019 Sep 1;145(5):1334-1345. doi: 10.1002/ijc.32222. Epub 2019 Mar 12.


Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity.

Leung ELH, Luo LX, Liu ZQ, Wong VKW, Lu LL, Xie Y, Zhang N, Qu YQ, Fan XX, Li Y, Huang M, Xiao DK, Huang J, Zhou YL, He JX, Ding J, Yao XJ, Ward DC, Liu L.

Cell Death Dis. 2018 Feb 13;9(2):216. doi: 10.1038/s41419-017-0065-9.


Acanthocytes in the McLeod phenotype of X-linked chronic granulomatous disease.

Beaulieu GP, Ward DC, Panch SR, Flegel WA.

Transfusion. 2017 Oct;57(10):2307-2308. doi: 10.1111/trf.14119. No abstract available.


Transfused neutrophils home to a joint with fungal infection.

Ward DC, Beaulieu GP, Leitman SF, Flegel WA.

Transfusion. 2016 Nov;56(11):2655-2656. doi: 10.1111/trf.13743. No abstract available.


Common Genetic Variants Found in HLA and KIR Immune Genes in Autism Spectrum Disorder.

Torres AR, Sweeten TL, Johnson RC, Odell D, Westover JB, Bray-Ward P, Ward DC, Davies CJ, Thomas AJ, Croen LA, Benson M.

Front Neurosci. 2016 Oct 20;10:463. eCollection 2016. Review.


A quality initiative of postoperative radiographic imaging performed on mastectomy specimens to reduce histology cost and pathology report turnaround time.

Kallen ME, Sim MS, Radosavcev BL, Humphries RM, Ward DC, Apple SK.

Ann Diagn Pathol. 2015 Oct;19(5):353-8. doi: 10.1016/j.anndiagpath.2015.07.007. Epub 2015 Jul 17.


Preparing for events for physically challenged athletes.

Simon LM, Ward DC.

Curr Sports Med Rep. 2014 May-Jun;13(3):163-8. doi: 10.1249/JSR.0000000000000058.


Activating killer-cell immunoglobulin-like receptors (KIR) and their cognate HLA ligands are significantly increased in autism.

Torres AR, Westover JB, Gibbons C, Johnson RC, Ward DC.

Brain Behav Immun. 2012 Oct;26(7):1122-7. doi: 10.1016/j.bbi.2012.07.014. Epub 2012 Aug 3.


Isolation, characterization, and in vitro propagation of infantile hemangioma stem cells and an in vivo mouse model.

Xu D, O TM, Shartava A, Fowles TC, Yang J, Fink LM, Ward DC, Mihm MC, Waner M, Ma Y.

J Hematol Oncol. 2011 Dec 22;4:54. doi: 10.1186/1756-8722-4-54.


Comparison of circulating MicroRNA 141 to circulating tumor cells, lactate dehydrogenase, and prostate-specific antigen for determining treatment response in patients with metastatic prostate cancer.

Gonzales JC, Fink LM, Goodman OB Jr, Symanowski JT, Vogelzang NJ, Ward DC.

Clin Genitourin Cancer. 2011 Sep;9(1):39-45. doi: 10.1016/j.clgc.2011.05.008. Epub 2011 Jul 1.


Circulating tumor cells as a predictive biomarker in patients with hormone-sensitive prostate cancer.

Goodman OB Jr, Symanowski JT, Loudyi A, Fink LM, Ward DC, Vogelzang NJ.

Clin Genitourin Cancer. 2011 Sep;9(1):31-8. doi: 10.1016/j.clgc.2011.04.001. Epub 2011 Jun 25.


Epithelial to mesenchymal transition (EMT) induced by bleomycin or TFG(b1)/EGF in murine induced pluripotent stem cell-derived alveolar Type II-like cells.

Alipio ZA, Jones N, Liao W, Yang J, Kulkarni S, Sree Kumar K, Hauer-Jensen M, Ward DC, Ma Y, Fink LM.

Differentiation. 2011 Sep;82(2):89-98. doi: 10.1016/j.diff.2011.05.001. Epub 2011 May 18.


A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer.

Zhu CS, Pinsky PF, Cramer DW, Ransohoff DF, Hartge P, Pfeiffer RM, Urban N, Mor G, Bast RC Jr, Moore LE, Lokshin AE, McIntosh MW, Skates SJ, Vitonis A, Zhang Z, Ward DC, Symanowski JT, Lomakin A, Fung ET, Sluss PM, Scholler N, Lu KH, Marrangoni AM, Patriotis C, Srivastava S, Buys SS, Berg CD; PLCO Project Team.

Cancer Prev Res (Phila). 2011 Mar;4(3):375-83. doi: 10.1158/1940-6207.CAPR-10-0193.


Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens.

Cramer DW, Bast RC Jr, Berg CD, Diamandis EP, Godwin AK, Hartge P, Lokshin AE, Lu KH, McIntosh MW, Mor G, Patriotis C, Pinsky PF, Thornquist MD, Scholler N, Skates SJ, Sluss PM, Srivastava S, Ward DC, Zhang Z, Zhu CS, Urban N.

Cancer Prev Res (Phila). 2011 Mar;4(3):365-74. doi: 10.1158/1940-6207.CAPR-10-0195.


Increases in quantitative D-dimer levels correlate with progressive disease better than circulating tumor cell counts in patients with refractory prostate cancer.

Khoury JD, Adcock DM, Chan F, Symanowski JT, Tiefenbacher S, Goodman O, Paz L, Ma Y, Ward DC, Vogelzang NJ, Fink LM.

Am J Clin Pathol. 2010 Dec;134(6):964-9. doi: 10.1309/AJCPH92SXYLIKKTS.


Tumor growth factor expression in obesity and changes in expression with weight loss: another cause of increased virulence and incidence of cancer in obesity.

Cottam D, Fisher B, Ziemba A, Atkinson J, Grace B, Ward DC, Pizzorno G.

Surg Obes Relat Dis. 2010 Sep-Oct;6(5):538-41. doi: 10.1016/j.soard.2010.04.011. Epub 2010 May 24.


Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic beta-like cells.

Alipio Z, Liao W, Roemer EJ, Waner M, Fink LM, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13426-31. doi: 10.1073/pnas.1007884107. Epub 2010 Jul 7.


Sustained factor VIII production in hemophiliac mice 1 year after engraftment with induced pluripotent stem cell-derived factor VIII producing endothelial cells.

Alipio Z, Adcock DM, Waner M, O TM, Fink LM, Ward DC, Ma Y.

Blood Coagul Fibrinolysis. 2010 Jul;21(5):502-4. doi: 10.1097/MBC.0b013e32833580e9. No abstract available.


Generation of murine hepatic lineage cells from induced pluripotent stem cells.

Gai H, Nguyen DM, Moon YJ, Aguila JR, Fink LM, Ward DC, Ma Y.

Differentiation. 2010 Mar;79(3):171-81. doi: 10.1016/j.diff.2010.01.002. Epub 2010 Jan 27.


Enhanced detection of staphylococcal genomes in positive blood cultures using a polymeric enzyme complex.

Klonoski J, Mondesire R, Rea L, Ward DC, Jenison RD.

Anal Biochem. 2010 Jan 15;396(2):284-9. doi: 10.1016/j.ab.2009.09.035. Epub 2009 Sep 25.


Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts.

Gai H, Leung EL, Costantino PD, Aguila JR, Nguyen DM, Fink LM, Ward DC, Ma Y.

Cell Biol Int. 2009 Nov;33(11):1184-93. doi: 10.1016/j.cellbi.2009.08.008. Epub 2009 Sep 1.


Double probing individual human spermatozoa: aniline blue staining for persistent histones and fluorescence in situ hybridization for aneuploidies.

Ovári L, Sati L, Stronk J, Borsos A, Ward DC, Huszar G.

Fertil Steril. 2010 May 1;93(7):2255-61. doi: 10.1016/j.fertnstert.2009.05.033. Epub 2009 Jul 9.


Circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors.

Goodman OB Jr, Fink LM, Symanowski JT, Wong B, Grobaski B, Pomerantz D, Ma Y, Ward DC, Vogelzang NJ.

Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1904-13. doi: 10.1158/1055-9965.EPI-08-1173.


A randomized controlled study of human serum albumin and serum substitute supplement as protein supplements for IVF culture and the effect on live birth rates.

Meintjes M, Chantilis SJ, Ward DC, Douglas JD, Rodriguez AJ, Guerami AR, Bookout DM, Barnett BD, Madden JD.

Hum Reprod. 2009 Apr;24(4):782-9. doi: 10.1093/humrep/den396. Epub 2009 Jan 14.


Phenotypic correction of murine hemophilia A using an iPS cell-based therapy.

Xu D, Alipio Z, Fink LM, Adcock DM, Yang J, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):808-13. doi: 10.1073/pnas.0812090106. Epub 2009 Jan 12.


Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells.

Yang J, Chai L, Fowles TC, Alipio Z, Xu D, Fink LM, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19756-61. doi: 10.1073/pnas.0809321105. Epub 2008 Dec 5.


SALL4 is a key regulator of survival and apoptosis in human leukemic cells.

Yang J, Chai L, Gao C, Fowles TC, Alipio Z, Dang H, Xu D, Fink LM, Ward DC, Ma Y.

Blood. 2008 Aug 1;112(3):805-13. doi: 10.1182/blood-2007-11-126326. Epub 2008 May 16. Erratum in: Blood. 2009 Oct 1; 114(14):3131.


Development of a rapid diagnostic assay for methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative Staphylococcus.

Lindsey WC, Woodruff ES, Weed D, Ward DC, Jenison RD.

Diagn Microbiol Infect Dis. 2008 Jul;61(3):273-9. doi: 10.1016/j.diagmicrobio.2008.03.002. Epub 2008 Apr 28.


Diagnostic markers for early detection of ovarian cancer.

Visintin I, Feng Z, Longton G, Ward DC, Alvero AB, Lai Y, Tenthorey J, Leiser A, Flores-Saaib R, Yu H, Azori M, Rutherford T, Schwartz PE, Mor G.

Clin Cancer Res. 2008 Feb 15;14(4):1065-72. doi: 10.1158/1078-0432.CCR-07-1569. Epub 2008 Feb 7. Erratum in: Clin Cancer Res. 2008 Aug 15;14(16):5308. Clin Cancer Res. 2008 Nov 1;14(21):7158.


Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells.

Yang J, Chai L, Liu F, Fink LM, Lin P, Silberstein LE, Amin HM, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10494-9. Epub 2007 Jun 8.


Dimensional assessment of X-bearing and Y-bearing haploid and disomic human sperm with the use of fluorescence in situ hybridization and objective morphometry.

Zavaczki Z, Celik-Ozenci C, Ovari L, Jakab A, Sati GL, Ward DC, Huszar G.

Fertil Steril. 2006 Jan;85(1):121-7.


Thin-film technology for direct visual detection of nucleic acid sequences: applications in clinical research.

Jenison RD, Bucala R, Maul D, Ward DC.

Expert Rev Mol Diagn. 2006 Jan;6(1):89-99. Review.


Simultaneous detection of microsatellite repeats and SNPs in the macrophage migration inhibitory factor (MIF) gene by thin-film biosensor chips and application to rural field studies.

Zhong XB, Leng L, Beitin A, Chen R, McDonald C, Hsiao B, Jenison RD, Kang I, Park SH, Lee A, Gregersen P, Thuma P, Bray-Ward P, Ward DC, Bucala R.

Nucleic Acids Res. 2005 Aug 2;33(13):e121.


Serum protein markers for early detection of ovarian cancer.

Mor G, Visintin I, Lai Y, Zhao H, Schwartz P, Rutherford T, Yue L, Bray-Ward P, Ward DC.

Proc Natl Acad Sci U S A. 2005 May 24;102(21):7677-82. Epub 2005 May 12.


Peptide conjugates for chromosomal gene targeting by triplex-forming oligonucleotides.

Rogers FA, Manoharan M, Rabinovitch P, Ward DC, Glazer PM.

Nucleic Acids Res. 2004 Dec 15;32(22):6595-604. Print 2004.


Candidate locus for Gilles de la Tourette syndrome/obsessive compulsive disorder/chronic tic disorder at 18q22.

Cuker A, State MW, King RA, Davis N, Ward DC.

Am J Med Genet A. 2004 Sep 15;130A(1):37-9.


A novel way of controlling rectal bleeding after transrectal ultrasonography-guided prostate biopsies.

Harris MA, Chadwick D, Ward DC.

BJU Int. 2004 Jun;93(9):1358. No abstract available.


[Numerical chromosome anomalies in human sperm at low sperm concentration].

Jakab A Jr, Kovács T, Kovanci E, Celik C, Vigue L, Borsos A, Ward DC, Huszár G.

Orv Hetil. 2003 Jul 27;144(30):1473-80. Hungarian.


Single-nucleotide polymorphism genotyping on optical thin-film biosensor chips.

Zhong XB, Reynolds R, Kidd JR, Kidd KK, Jenison R, Marlar RA, Ward DC.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11559-64. Epub 2003 Sep 15.


Forensic discrimination of photocopy and printer toners. III. Multivariate statistics applied to scanning electron microscopy and pyrolysis gas chromatography/mass spectrometry.

Egan WJ, Galipo RC, Kochanowski BK, Morgan SL, Bartick EG, Miller ML, Ward DC, Mothershead RF 2nd.

Anal Bioanal Chem. 2003 Aug;376(8):1286-97. Epub 2003 Jul 19.


Chemical extraction methods to assess bioavailable arsenic in soil and solid media.

Rodriguez RR, Basta NT, Casteel SW, Armstrong FP, Ward DC.

J Environ Qual. 2003 May-Jun;32(3):876-84.


Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype.

State MW, Greally JM, Cuker A, Bowers PN, Henegariu O, Morgan TM, Gunel M, DiLuna M, King RA, Nelson C, Donovan A, Anderson GM, Leckman JF, Hawkins T, Pauls DL, Lifton RP, Ward DC.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4684-9. Epub 2003 Apr 7.


Detection of chromosomal instability in paired breast surgery and ductal lavage specimens by interphase fluorescence in situ hybridization.

King BL, Tsai SC, Gryga ME, D'Aquila TG, Seelig SA, Morrison LE, Jacobson KK, Legator MS, Ward DC, Rimm DL, Phillips RF.

Clin Cancer Res. 2003 Apr;9(4):1509-16.


The use of SEM/EDS analysis to distinguish dental and osseus tissue from other materials.

Ubelaker DH, Ward DC, Braz VS, Stewart J.

J Forensic Sci. 2002 Sep;47(5):940-3.


Rapid DNA fiber technique for size measurements of linear and circular DNA probes.

Henegariu O, Grober L, Haskins W, Bowers PN, State MW, Ohmido N, Bray-Ward P, Ward DC.

Biotechniques. 2001 Aug;31(2):246-50. No abstract available.


FISH assessment of aneuploidy frequencies in mature and immature human spermatozoa classified by the absence or presence of cytoplasmic retention.

Kovanci E, Kovacs T, Moretti E, Vigue L, Bray-Ward P, Ward DC, Huszar G.

Hum Reprod. 2001 Jun;16(6):1209-17.


A triple color FISH technique for mouse chromosome identification.

Henegariu O, Dunai J, Chen XN, Korenberg JR, Ward DC, Greally JM.

Mamm Genome. 2001 Jun;12(6):462-5. No abstract available.


Cryptic translocation identification in human and mouse using several telomeric multiplex fish (TM-FISH) strategies.

Henegariu O, Artan S, Greally JM, Chen XN, Korenberg JR, Vance GH, Stubbs L, Bray-Ward P, Ward DC.

Lab Invest. 2001 Apr;81(4):483-91.


Small marker chromosome identification in metaphase and interphase using centromeric multiplex fish (CM-FISH).

Henegariu O, Bray-Ward P, Artan S, Vance GH, Qumsyieh M, Ward DC.

Lab Invest. 2001 Apr;81(4):475-81.


Visualization of oligonucleotide probes and point mutations in interphase nuclei and DNA fibers using rolling circle DNA amplification.

Zhong XB, Lizardi PM, Huang XH, Bray-Ward PL, Ward DC.

Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3940-5.

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