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Items: 30


Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations.

Zhu J, Message SD, Mallia P, Kebadze T, Contoli M, Ward CK, Barnathan ES, Mascelli MA, Kon OM, Papi A, Stanciu LA, Edwards MR, Jeffery PK, Johnston SL.

J Allergy Clin Immunol. 2019 Jan;143(1):114-125.e4. doi: 10.1016/j.jaci.2018.04.003. Epub 2018 Apr 24.


IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD.

Briend E, Ferguson GJ, Mori M, Damera G, Stephenson K, Karp NA, Sethi S, Ward CK, Sleeman MA, Erjefält JS, Finch DK.

Respir Res. 2017 Aug 22;18(1):159. doi: 10.1186/s12931-017-0641-7.


A randomised, placebo-controlled trial of anti-interleukin-1 receptor 1 monoclonal antibody MEDI8968 in chronic obstructive pulmonary disease.

Calverley PMA, Sethi S, Dawson M, Ward CK, Finch DK, Penney M, Newbold P, van der Merwe R.

Respir Res. 2017 Aug 9;18(1):153. doi: 10.1186/s12931-017-0633-7.


A Sputum Proteomic Signature That Associates with Increased IL-1β Levels and Bacterial Exacerbations of COPD.

Damera G, Pham TH, Zhang J, Ward CK, Newbold P, Ranade K, Sethi S.

Lung. 2016 Jun;194(3):363-9. doi: 10.1007/s00408-016-9877-0. Epub 2016 Apr 15.


Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection.

Kearley J, Silver JS, Sanden C, Liu Z, Berlin AA, White N, Mori M, Pham TH, Ward CK, Criner GJ, Marchetti N, Mustelin T, Erjefalt JS, Kolbeck R, Humbles AA.

Immunity. 2015 Mar 17;42(3):566-79. doi: 10.1016/j.immuni.2015.02.011.


Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study.

Castro M, Wenzel SE, Bleecker ER, Pizzichini E, Kuna P, Busse WW, Gossage DL, Ward CK, Wu Y, Wang B, Khatry DB, van der Merwe R, Kolbeck R, Molfino NA, Raible DG.

Lancet Respir Med. 2014 Nov;2(11):879-890. doi: 10.1016/S2213-2600(14)70201-2. Epub 2014 Oct 8.


Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study.

Brightling CE, Bleecker ER, Panettieri RA Jr, Bafadhel M, She D, Ward CK, Xu X, Birrell C, van der Merwe R.

Lancet Respir Med. 2014 Nov;2(11):891-901. doi: 10.1016/S2213-2600(14)70187-0. Epub 2014 Sep 7.


High blood eosinophil count is associated with more frequent asthma attacks in asthma patients.

Tran TN, Khatry DB, Ke X, Ward CK, Gossage D.

Ann Allergy Asthma Immunol. 2014 Jul;113(1):19-24. doi: 10.1016/j.anai.2014.04.011. Epub 2014 May 18.


Effect of a Punica granatum enriched diet on immunocompetence in Rhinella marina.

Parker AN, Ward CK, Estes NR 2nd.

J Exp Zool A Ecol Genet Physiol. 2014 Jul;321(6):316-23. doi: 10.1002/jez.1860. Epub 2014 Mar 24.


Airway inflammation and illness severity in response to experimental rhinovirus infection in asthma.

Zhu J, Message SD, Qiu Y, Mallia P, Kebadze T, Contoli M, Ward CK, Barnathan ES, Mascelli MA, Kon OM, Papi A, Stanciu LA, Jeffery PK, Johnston SL.

Chest. 2014 Jun;145(6):1219-1229. doi: 10.1378/chest.13-1567.


Loss of toll-like receptor 3 function improves glucose tolerance and reduces liver steatosis in obese mice.

Wu LH, Huang CC, Adhikarakunnathu S, San Mateo LR, Duffy KE, Rafferty P, Bugelski P, Raymond H, Deutsch H, Picha K, Ward CK, Alexoupolou L, Flavell RA, Mbow ML, Susulic VS.

Metabolism. 2012 Nov;61(11):1633-45. doi: 10.1016/j.metabol.2012.04.015. Epub 2012 May 17.


Comparative effects of carbapenems on bacterial load and host immune response in a Klebsiella pneumoniae murine pneumonia model.

Hilliard JJ, Melton JL, Hall L, Abbanat D, Fernandez J, Ward CK, Bunting RA, Barron A, Lynch AS, Flamm RK.

Antimicrob Agents Chemother. 2011 Feb;55(2):836-44. doi: 10.1128/AAC.00670-10. Epub 2010 Dec 6.


Novel antagonist antibody to TLR3 blocks poly(I:C)-induced inflammation in vivo and in vitro.

Bunting RA, Duffy KE, Lamb RJ, San Mateo LR, Smalley K, Raymond H, Liu X, Petley T, Fisher J, Beck H, Flavell RA, Alexopoulou L, Ward CK.

Cell Immunol. 2011;267(1):9-16. doi: 10.1016/j.cellimm.2010.10.008. Epub 2010 Nov 2.


Reproductive parameters in female yellow-blotched map turtles (Graptemys flavimaculata) from a historically contaminated site vs. a reference site.

Shelby-Walker JA, Ward CK, Mendonça MT.

Comp Biochem Physiol A Mol Integr Physiol. 2009 Nov;154(3):401-8. doi: 10.1016/j.cbpa.2009.07.020. Epub 2009 Aug 3.


Characterization and quantification of corticosteroid-binding globulin in a southern toad, Bufo terrestris, exposed to coal-combustion-waste.

Ward CK, Fontes C, Breuner CW, Mendonça MT.

Gen Comp Endocrinol. 2007 May 15;152(1):82-8. Epub 2007 Mar 12.


Metabolic measures of male southern toads (Bufo terrestris) exposed to coal combustion waste.

Ward CK, Appel AG, Mendonça MT.

Comp Biochem Physiol A Mol Integr Physiol. 2006 Mar;143(3):353-60. Epub 2006 Jan 31.


Mutations in the lspA1 and lspA2 genes of Haemophilus ducreyi affect the virulence of this pathogen in an animal model system.

Ward CK, Latimer JL, Nika J, Vakevainen M, Mock JR, Deng K, Blick RJ, Hansen EJ.

Infect Immun. 2003 May;71(5):2478-86. Erratum in: Infect Immun. 2004 Feb;72(2):1221.


Haemophilus ducreyi requires the flp gene cluster for microcolony formation in vitro.

Nika JR, Latimer JL, Ward CK, Blick RJ, Wagner NJ, Cope LD, Mahairas GG, Munson RS Jr, Hansen EJ.

Infect Immun. 2002 Jun;70(6):2965-75.


Characterization of Haemophilus ducreyi cdtA, cdtB, and cdtC mutants in in vitro and in vivo systems.

Lewis DA, Stevens MK, Latimer JL, Ward CK, Deng K, Blick R, Lumbley SR, Ison CA, Hansen EJ.

Infect Immun. 2001 Sep;69(9):5626-34.


Identification of the znuA-encoded periplasmic zinc transport protein of Haemophilus ducreyi.

Lewis DA, Klesney-Tait J, Lumbley SR, Ward CK, Latimer JL, Ison CA, Hansen EJ.

Infect Immun. 1999 Oct;67(10):5060-8.


Characterization of a Haemophilus ducreyi mutant deficient in expression of cytolethal distending toxin.

Stevens MK, Latimer JL, Lumbley SR, Ward CK, Cope LD, Lagergard T, Hansen EJ.

Infect Immun. 1999 Aug;67(8):3900-8.


Effects of cyclic loading on selected post-and-core systems.

Reagan SE, Fruits TJ, Van Brunt CL, Ward CK.

Quintessence Int. 1999 Jan;30(1):61-7.


Haemophilus ducreyi secretes a filamentous hemagglutinin-like protein.

Ward CK, Lumbley SR, Latimer JL, Cope LD, Hansen EJ.

J Bacteriol. 1998 Nov;180(22):6013-22.


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