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Items: 22

1.

Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition.

Chung CY, Shin HR, Berdan CA, Ford B, Ward CC, Olzmann JA, Zoncu R, Nomura DK.

Nat Chem Biol. 2019 Aug;15(8):776-785. doi: 10.1038/s41589-019-0308-4. Epub 2019 Jul 8.

2.

Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.

Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK.

Nat Chem Biol. 2019 Jul;15(7):747-755. doi: 10.1038/s41589-019-0304-8. Epub 2019 Jun 17.

3.

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications.

Ward CC, Kleinman JI, Brittain SM, Lee PS, Chung CYS, Kim K, Petri Y, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Nomura DK.

ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.

PMID:
31059647
4.

A Third Ventricle?

Ward CC, Schmidt GA.

Ann Am Thorac Soc. 2019 May;16(5):631-635. doi: 10.1513/AnnalsATS.201811-808CC. No abstract available.

PMID:
31042095
5.

Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State.

Magtanong L, Ko PJ, To M, Cao JY, Forcina GC, Tarangelo A, Ward CC, Cho K, Patti GJ, Nomura DK, Olzmann JA, Dixon SJ.

Cell Chem Biol. 2019 Mar 21;26(3):420-432.e9. doi: 10.1016/j.chembiol.2018.11.016. Epub 2019 Jan 24.

PMID:
30686757
6.

Evaluation and Management of Maternal Congenital Heart Disease: A Review.

Hopkins MK, Goldstein SA, Ward CC, Kuller JA.

Obstet Gynecol Surv. 2018 Feb;73(2):116-124. doi: 10.1097/OGX.0000000000000536. Review.

PMID:
29480926
7.

Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products.

Grossman EA, Ward CC, Spradlin JN, Bateman LA, Huffman TR, Miyamoto DK, Kleinman JI, Nomura DK.

Cell Chem Biol. 2017 Nov 16;24(11):1368-1376.e4. doi: 10.1016/j.chembiol.2017.08.013. Epub 2017 Sep 14.

8.

Congenital and Acquired Valvular Heart Disease in Pregnancy.

Goldstein SA, Ward CC.

Curr Cardiol Rep. 2017 Aug 24;19(10):96. doi: 10.1007/s11886-017-0910-6. Review.

PMID:
28840470
9.

NHS-Esters As Versatile Reactivity-Based Probes for Mapping Proteome-Wide Ligandable Hotspots.

Ward CC, Kleinman JI, Nomura DK.

ACS Chem Biol. 2017 Jun 16;12(6):1478-1483. doi: 10.1021/acschembio.7b00125. Epub 2017 May 1.

PMID:
28445029
10.

Activity-based protein profiling for mapping and pharmacologically interrogating proteome-wide ligandable hotspots.

Roberts AM, Ward CC, Nomura DK.

Curr Opin Biotechnol. 2017 Feb;43:25-33. doi: 10.1016/j.copbio.2016.08.003. Epub 2016 Aug 26. Review.

11.

Initial Experience of Left Ventricular Assist Device Support for Adult Patients with Transposition of the Great Vessels.

Menachem JN, Swaminathan AC, Bashore TM, Ward CC, Rogers JG, Milano CA, Patel CB.

Congenit Heart Dis. 2015 Sep-Oct;10(5):382-6. doi: 10.1111/chd.12264. Epub 2015 Apr 27. No abstract available.

PMID:
25913866
12.

Discovery of human sORF-encoded polypeptides (SEPs) in cell lines and tissue.

Ma J, Ward CC, Jungreis I, Slavoff SA, Schwaid AG, Neveu J, Budnik BA, Kellis M, Saghatelian A.

J Proteome Res. 2014 Mar 7;13(3):1757-65. doi: 10.1021/pr401280w. Epub 2014 Feb 14.

13.

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection.

Goujon C, Moncorgé O, Bauby H, Doyle T, Ward CC, Schaller T, Hué S, Barclay WS, Schulz R, Malim MH.

Nature. 2013 Oct 24;502(7472):559-62. doi: 10.1038/nature12542. Epub 2013 Sep 18.

14.

STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle.

Stiber J, Hawkins A, Zhang ZS, Wang S, Burch J, Graham V, Ward CC, Seth M, Finch E, Malouf N, Williams RS, Eu JP, Rosenberg P.

Nat Cell Biol. 2008 Jun;10(6):688-97. doi: 10.1038/ncb1731. Epub 2008 May 18.

15.

Directed postgraduate study result in quantitative improvement in American Board of Surgery In-Training Exam scores.

Mahmoud A, Andrus CH, Matolo NM, Ward CC.

Am J Surg. 2006 Jun;191(6):812-6.

PMID:
16720155
16.

Secondary heart field contributes myocardium and smooth muscle to the arterial pole of the developing heart.

Waldo KL, Hutson MR, Ward CC, Zdanowicz M, Stadt HA, Kumiski D, Abu-Issa R, Kirby ML.

Dev Biol. 2005 May 1;281(1):78-90.

17.

Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity.

Hughes DA, Vilar FJ, Ward CC, Alfirevic A, Park BK, Pirmohamed M.

Pharmacogenetics. 2004 Jun;14(6):335-42.

PMID:
15247625
18.

Mechanisms and pathophysiology of mild head injury.

Elson LM, Ward CC.

Semin Neurol. 1994 Mar;14(1):8-18. Review. No abstract available.

PMID:
8029564
19.

Focus of epithelial dysplasia arising in hereditary gingival fibromatosis.

Redman RS, Ward CC, Patterson RH.

J Periodontol. 1985 Mar;56(3):158-62.

PMID:
3857322
20.

Deoxyribonucleic acid output in the sputum from cystic fibrosis patients.

Carswell F, Robinson DW, Ward CC, Waterfield MR.

Eur J Respir Dis. 1984 Jan;65(1):53-7.

PMID:
6705858
21.

Biodynamic finite element models used in brain injury research.

Ward CC, Nikravesh PE, Thompson RB.

Aviat Space Environ Med. 1978 Jan;49(1 Pt. 2):136-42.

PMID:
623576
22.

Head trauma--a parametric dynamic study.

Roberts SB, Ward CC, Nahum AM.

J Biomech. 1969 Oct;2(4):397-415. No abstract available.

PMID:
16335140

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