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Sequencing of high-efficacy disease-modifying therapies in multiple sclerosis: perspectives and approaches.

Grand'Maison F, Yeung M, Morrow SA, Lee L, Emond F, Ward BJ, Laneuville P, Schecter R.

Neural Regen Res. 2018 Nov;13(11):1871-1874. doi: 10.4103/1673-5374.239432. Review.


Low levels of detectable pertussis antibody among a large cohort of pregnant women in Canada.

Brooks JI, Bell CA, Rotondo J, Gilbert NL, Tunis M, Ward BJ, Desai S.

Vaccine. 2018 Oct 1;36(41):6138-6143. doi: 10.1016/j.vaccine.2018.08.066. Epub 2018 Sep 1.


Methods to reliably estimate faecal sludge quantities and qualities for the design of treatment technologies and management solutions.

Strande L, Schoebitz L, Bischoff F, Ddiba D, Okello F, Englund M, Ward BJ, Niwagaba CB.

J Environ Manage. 2018 Oct 1;223:898-907. doi: 10.1016/j.jenvman.2018.06.100. Epub 2018 Jul 10.


A novel serological assay for influenza based on DiD fluorescence dequenching that is free from observer bias and potentially automatable - A proof of concept study.

Makarkov AI, Patel AR, Bainov V, Ward BJ.

Vaccine. 2018 Jul 16;36(30):4485-4493. doi: 10.1016/j.vaccine.2018.06.032. Epub 2018 Jun 19.


Neonatal Immunity, Respiratory Virus Infections, and the Development of Asthma.

Restori KH, Srinivasa BT, Ward BJ, Fixman ED.

Front Immunol. 2018 Jun 4;9:1249. doi: 10.3389/fimmu.2018.01249. eCollection 2018. Review.


A combined experimental and computational study on the reaction of fluoroarenes with Mg-Mg, Mg-Zn, Mg-Al and Al-Zn bonds.

Bakewell C, Ward BJ, White AJP, Crimmin MR.

Chem Sci. 2018 Jan 23;9(8):2348-2356. doi: 10.1039/c7sc05059c. eCollection 2018 Feb 28.


The ash dieback invasion of Europe was founded by two genetically divergent individuals.

McMullan M, Rafiqi M, Kaithakottil G, Clavijo BJ, Bilham L, Orton E, Percival-Alwyn L, Ward BJ, Edwards A, Saunders DGO, Garcia Accinelli G, Wright J, Verweij W, Koutsovoulos G, Yoshida K, Hosoya T, Williamson L, Jennings P, Ioos R, Husson C, Hietala AM, Vivian-Smith A, Solheim H, MaClean D, Fosker C, Hall N, Brown JKM, Swarbreck D, Blaxter M, Downie JA, Clark MD.

Nat Ecol Evol. 2018 Jun;2(6):1000-1008. doi: 10.1038/s41559-018-0548-9. Epub 2018 Apr 23.


Progressive multifocal leukoencephalopathy after fingolimod treatment.

Berger JR, Cree BA, Greenberg B, Hemmer B, Ward BJ, Dong VM, Merschhemke M.

Neurology. 2018 May 15;90(20):e1815-e1821. doi: 10.1212/WNL.0000000000005529. Epub 2018 Apr 18.


Proteomic fingerprinting in HIV/HCV co-infection reveals serum biomarkers for the diagnosis of fibrosis staging.

Golizeh M, Melendez-Pena CE, Ward BJ, Saeed S, Santamaria C, Conway B, Cooper C, Klein MB, Ndao M; Canadian Co-Infection Cohort (CTN222).

PLoS One. 2018 Apr 2;13(4):e0195148. doi: 10.1371/journal.pone.0195148. eCollection 2018.


Sequencing of disease-modifying therapies for relapsing-remitting multiple sclerosis: a theoretical approach to optimizing treatment.

Grand'Maison F, Yeung M, Morrow SA, Lee L, Emond F, Ward BJ, Laneuville P, Schecter R.

Curr Med Res Opin. 2018 Aug;34(8):1419-1430. doi: 10.1080/03007995.2018.1458023. Epub 2018 Apr 18.


Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy.

Lindsay BJ, Bonar MM, Costas-Cancelas IN, Hunt K, Makarkov AI, Chierzi S, Krawczyk CM, Landry N, Ward BJ, Rouiller I.

Vaccine. 2018 Apr 12;36(16):2147-2154. doi: 10.1016/j.vaccine.2018.02.106. Epub 2018 Mar 14.


Humoral and cell-mediated immune responses to H5N1 plant-made virus-like particle vaccine are differentially impacted by alum and GLA-SE adjuvants in a Phase 2 clinical trial.

Pillet S, Aubin É, Trépanier S, Poulin JF, Yassine-Diab B, Ter Meulen J, Ward BJ, Landry N.

NPJ Vaccines. 2018 Jan 23;3:3. doi: 10.1038/s41541-017-0043-3. eCollection 2018.


Review of synthetic human faeces and faecal sludge for sanitation and wastewater research.

Penn R, Ward BJ, Strande L, Maurer M.

Water Res. 2018 Apr 1;132:222-240. doi: 10.1016/j.watres.2017.12.063. Epub 2017 Dec 30. Review.


The establishment of surrogates and correlates of protection: Useful tools for the licensure of effective influenza vaccines?

Ward BJ, Pillet S, Charland N, Trepanier S, Couillard J, Landry N.

Hum Vaccin Immunother. 2018 Mar 4;14(3):647-656. doi: 10.1080/21645515.2017.1413518. Epub 2018 Jan 16.


A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults.

Ostergaard L, Vesikari T, Absalon J, Beeslaar J, Ward BJ, Senders S, Eiden JJ, Jansen KU, Anderson AS, York LJ, Jones TR, Harris SL, O'Neill R, Radley D, Maansson R, Prégaldien JL, Ginis J, Staerke NB, Perez JL; B1971009 and B1971016 Trial Investigators.

N Engl J Med. 2017 Dec 14;377(24):2349-2362. doi: 10.1056/NEJMoa1614474.


Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen.

Lighten J, Papadopulos AST, Mohammed RS, Ward BJ, G Paterson I, Baillie L, Bradbury IR, Hendry AP, Bentzen P, van Oosterhout C.

Nat Commun. 2017 Nov 3;8(1):1294. doi: 10.1038/s41467-017-01183-2.


Plant-made virus-like particles bearing influenza hemagglutinin (HA) recapitulate early interactions of native influenza virions with human monocytes/macrophages.

Makarkov AI, Chierzi S, Pillet S, Murai KK, Landry N, Ward BJ.

Vaccine. 2017 Aug 16;35(35 Pt B):4629-4636. doi: 10.1016/j.vaccine.2017.07.012. Epub 2017 Jul 13.


Serum Carbonic Anhydrase 1 is a Biomarker for Diagnosis of Human Schistosoma mansoni Infection.

Kardoush MI, Ward BJ, Ndao M.

Am J Trop Med Hyg. 2017 Apr;96(4):842-849. doi: 10.4269/ajtmh.16-0021.


Seroprevalence of rubella antibodies and determinants of susceptibility to rubella in a cohort of pregnant women in Canada, 2008-2011.

Gilbert NL, Rotondo J, Shapiro J, Sherrard L, Fraser WD, Ward BJ.

Vaccine. 2017 May 25;35(23):3050-3055. doi: 10.1016/j.vaccine.2017.04.057. Epub 2017 Apr 29.


Plant-made virus-like particle vaccines bearing the hemagglutinin of either seasonal (H1) or avian (H5) influenza have distinct patterns of interaction with human immune cells in vitro.

Hendin HE, Pillet S, Lara AN, Wu CY, Charland N, Landry N, Ward BJ.

Vaccine. 2017 May 2;35(19):2592-2599. doi: 10.1016/j.vaccine.2017.03.058.


Single radial haemolysis compared to haemagglutinin inhibition and microneutralization as a correlate of protection against influenza A H3N2 in children and adolescents.

Wang B, Russell ML, Brewer A, Newton J, Singh P, Ward BJ, Loeb M.

Influenza Other Respir Viruses. 2017 May;11(3):283-288. doi: 10.1111/irv.12450. Epub 2017 Mar 16.


Influenza Vaccination of Healthcare Workers: Critical Analysis of the Evidence for Patient Benefit Underpinning Policies of Enforcement.

De Serres G, Skowronski DM, Ward BJ, Gardam M, Lemieux C, Yassi A, Patrick DM, Krajden M, Loeb M, Collignon P, Carrat F.

PLoS One. 2017 Jan 27;12(1):e0163586. doi: 10.1371/journal.pone.0163586. eCollection 2017.


Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus.

Mock T, Otillar RP, Strauss J, McMullan M, Paajanen P, Schmutz J, Salamov A, Sanges R, Toseland A, Ward BJ, Allen AE, Dupont CL, Frickenhaus S, Maumus F, Veluchamy A, Wu T, Barry KW, Falciatore A, Ferrante MI, Fortunato AE, Glöckner G, Gruber A, Hipkin R, Janech MG, Kroth PG, Leese F, Lindquist EA, Lyon BR, Martin J, Mayer C, Parker M, Quesneville H, Raymond JA, Uhlig C, Valas RE, Valentin KU, Worden AZ, Armbrust EV, Clark MD, Bowler C, Green BR, Moulton V, van Oosterhout C, Grigoriev IV.

Nature. 2017 Jan 26;541(7638):536-540. doi: 10.1038/nature20803. Epub 2017 Jan 16.


Travellers and influenza: risks and prevention.

Goeijenbier M, van Genderen P, Ward BJ, Wilder-Smith A, Steffen R, Osterhaus AD.

J Travel Med. 2017 Jan 11;24(1). pii: taw078. doi: 10.1093/jtm/taw078. Print 2017 Jan. Review.


Protocols for the Investigation of Information Processing in Human Assessment of Fundamental Movement Skills.

Ward BJ, Thornton A, Lay B, Rosenberg M.

J Mot Behav. 2017 Nov-Dec;49(6):593-602. doi: 10.1080/00222895.2016.1247033. Epub 2016 Dec 23.


Adaptive phenotypic response to climate enabled by epigenetics in a K-strategy species, the fish Leucoraja ocellata (Rajidae).

Lighten J, Incarnato D, Ward BJ, van Oosterhout C, Bradbury I, Hanson M, Bentzen P.

R Soc Open Sci. 2016 Oct 26;3(10):160299. eCollection 2016 Oct.


Low hemagglutinin antigen dose influenza vaccines adjuvanted with AS03 alter the long-term immune responses in BALB/c mice.

Yam KK, Brewer A, Bleau V, Beaulieu É, Mallett CP, Ward BJ.

Hum Vaccin Immunother. 2017 Mar 4;13(3):561-571. doi: 10.1080/21645515.2016.1241360. Epub 2016 Oct 21.


Correction: Microneutralization Assay Titres Correlate with Protection against Seasonal Influenza H1N1 and H3N2 in Children.

Verschoor CP, Singh P, Russell ML, Bowdish DM, Brewer A, Cyr L, Ward BJ, Loeb M.

PLoS One. 2016 Sep 22;11(9):e0163830. doi: 10.1371/journal.pone.0163830. eCollection 2016.


STAT6 inhibitory peptide given during RSV infection of neonatal mice reduces exacerbated airway responses upon adult reinfection.

Srinivasa BT, Restori KH, Shan J, Cyr L, Xing L, Lee S, Ward BJ, Fixman ED.

J Leukoc Biol. 2017 Feb;101(2):519-529. doi: 10.1189/jlb.4A0215-062RR. Epub 2016 Aug 26.


Identification of Candidate Serum Biomarkers for Schistosoma mansoni Infected Mice Using Multiple Proteomic Platforms.

Kardoush MI, Ward BJ, Ndao M.

PLoS One. 2016 May 3;11(5):e0154465. doi: 10.1371/journal.pone.0154465. eCollection 2016.


A plant-derived quadrivalent virus like particle influenza vaccine induces cross-reactive antibody and T cell response in healthy adults.

Pillet S, Aubin É, Trépanier S, Bussière D, Dargis M, Poulin JF, Yassine-Diab B, Ward BJ, Landry N.

Clin Immunol. 2016 Jul;168:72-87. doi: 10.1016/j.clim.2016.03.008. Epub 2016 Mar 14.


Comparison of AS03 and Alum on immune responses elicited by A/H3N2 split influenza vaccine in young, mature and aged BALB/c mice.

Yam KK, Gupta J, Allen EK, Burt KR, Beaulieu É, Mallett CP, Burt DS, Ward BJ.

Vaccine. 2016 Mar 14;34(12):1444-51. doi: 10.1016/j.vaccine.2016.02.012. Epub 2016 Feb 9.


Standardization of Hemagglutination Inhibition Assay for Influenza Serology Allows for High Reproducibility between Laboratories.

Zacour M, Ward BJ, Brewer A, Tang P, Boivin G, Li Y, Warhuus M, McNeil SA, LeBlanc JJ, Hatchette TF; Public Health Agency of Canada and Canadian Institutes of Health Influenza Research Network (PCIRN).

Clin Vaccine Immunol. 2016 Jan 27;23(3):236-42. doi: 10.1128/CVI.00613-15.


Plant-derived H7 VLP vaccine elicits protective immune response against H7N9 influenza virus in mice and ferrets.

Pillet S, Racine T, Nfon C, Di Lenardo TZ, Babiuk S, Ward BJ, Kobinger GP, Landry N.

Vaccine. 2015 Nov 17;33(46):6282-9. doi: 10.1016/j.vaccine.2015.09.065. Epub 2015 Oct 2.


The Effect of Deworming on Growth in One-Year-Old Children Living in a Soil-Transmitted Helminth-Endemic Area of Peru: A Randomized Controlled Trial.

Joseph SA, Casapía M, Montresor A, Rahme E, Ward BJ, Marquis GS, Pezo L, Blouin B, Maheu-Giroux M, Gyorkos TW.

PLoS Negl Trop Dis. 2015 Oct 1;9(10):e0004020. doi: 10.1371/journal.pntd.0004020. eCollection 2015. Erratum in: PLoS Negl Trop Dis. 2015 Dec;9(12):e0004288.


HYBRIDCHECK: software for the rapid detection, visualization and dating of recombinant regions in genome sequence data.

Ward BJ, van Oosterhout C.

Mol Ecol Resour. 2016 Mar;16(2):534-9. doi: 10.1111/1755-0998.12469. Epub 2015 Oct 12.


A family cluster of Chagas disease detected through selective screening of blood donors: A case report and brief review.

Mongeau-Martin G, Ndao M, Libman M, Delage G, Ward BJ.

Can J Infect Dis Med Microbiol. 2015 May-Jun;26(3):157-61.


Microneutralization assay titres correlate with protection against seasonal influenza H1N1 and H3N2 in children.

Verschoor CP, Singh P, Russell ML, Bowdish DM, Brewer A, Cyr L, Ward BJ, Loeb M.

PLoS One. 2015 Jun 24;10(6):e0131531. doi: 10.1371/journal.pone.0131531. eCollection 2015. Erratum in: PLoS One. 2016;11(9):e0163830.


Generation and characterization of a trackable plant-made influenza H5 virus-like particle (VLP) containing enhanced green fluorescent protein (eGFP).

Young KR, Arthus-Cartier G, Yam KK, Lavoie PO, Landry N, D'Aoust MA, Vézina LP, Couture MM, Ward BJ.

FASEB J. 2015 Sep;29(9):3817-27. doi: 10.1096/fj.15-270421. Epub 2015 Jun 2.


AS03-Adjuvanted, Very-Low-Dose Influenza Vaccines Induce Distinctive Immune Responses Compared to Unadjuvanted High-Dose Vaccines in BALB/c Mice.

Yam KK, Gupta J, Winter K, Allen E, Brewer A, Beaulieu É, Mallett CP, Burt DS, Ward BJ.

Front Immunol. 2015 Apr 29;6:207. doi: 10.3389/fimmu.2015.00207. eCollection 2015.


Dermatoses among returned Canadian travellers and immigrants: surveillance report based on CanTravNet data, 2009-2012.

Stevens MS, Geduld J, Libman M, Ward BJ, McCarthy AE, Vincelette J, Ghesquiere W, Hajek J, Kuhn S, Freedman DO, Kain KC, Boggild AK.

CMAJ Open. 2015 Jan 13;3(1):E119-26. doi: 10.9778/cmajo.20140082. eCollection 2015 Jan-Mar.


Evidence for suppression of immunity as a driver for genomic introgressions and host range expansion in races of Albugo candida, a generalist parasite.

McMullan M, Gardiner A, Bailey K, Kemen E, Ward BJ, Cevik V, Robert-Seilaniantz A, Schultz-Larsen T, Balmuth A, Holub E, van Oosterhout C, Jones JD.

Elife. 2015 Feb 27;4. doi: 10.7554/eLife.04550.


Discovery and characterization of potential prognostic biomarkers for dengue hemorrhagic fever.

Poole-Smith BK, Gilbert A, Gonzalez AL, Beltran M, Tomashek KM, Ward BJ, Hunsperger EA, Ndao M.

Am J Trop Med Hyg. 2014 Dec;91(6):1218-26. doi: 10.4269/ajtmh.14-0193. Epub 2014 Oct 27.


Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines.

Ward BJ, Landry N, Trépanier S, Mercier G, Dargis M, Couture M, D'Aoust MA, Vézina LP.

Vaccine. 2014 Oct 21;32(46):6098-106. doi: 10.1016/j.vaccine.2014.08.079. Epub 2014 Sep 19.


Travel-acquired infections in Canada: CanTravNet 2011-2012.

Boggild AK, Geduld J, Libman M, Ward BJ, McCarthy A, Hajek J, Ghesquiere W, Vincelette J, Kuhn S, Freedman DO, Kain KC.

Can Commun Dis Rep. 2014 Sep 18;40(16):313-325. eCollection 2014 Sep 18.


Bypassing a highly unstable frustrated Lewis pair: dihydrogen cleavage by a thermally robust silylium-phosphine adduct.

Herrington TJ, Ward BJ, Doyle LR, McDermott J, White AJ, Hunt PA, Ashley AE.

Chem Commun (Camb). 2014 Oct 28;50(84):12753-6. doi: 10.1039/c4cc05905k.


Influenza virus-like particle vaccines made in Nicotiana benthamiana elicit durable, poly-functional and cross-reactive T cell responses to influenza HA antigens.

Landry N, Pillet S, Favre D, Poulin JF, Trépanier S, Yassine-Diab B, Ward BJ.

Clin Immunol. 2014 Oct;154(2):164-77. doi: 10.1016/j.clim.2014.08.003. Epub 2014 Aug 14.


Development of a rapid serological assay for the diagnosis of strongyloidiasis using a novel diffraction-based biosensor technology.

Pak BJ, Vasquez-Camargo F, Kalinichenko E, Chiodini PL, Nutman TB, Tanowitz HB, McAuliffe I, Wilkins P, Smith PT, Ward BJ, Libman MD, Ndao M.

PLoS Negl Trop Dis. 2014 Aug 7;8(8):e3002. doi: 10.1371/journal.pntd.0003002. eCollection 2014 Aug.


Evaluation of solid fuel char briquettes from human waste.

Ward BJ, Yacob TW, Montoya LD.

Environ Sci Technol. 2014 Aug 19;48(16):9852-8. doi: 10.1021/es500197h. Epub 2014 Jul 25.


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