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Items: 1 to 50 of 112

1.

Pathogenic and non-pathogenic Escherichia coli colonization and host inflammatory response in a defined microbiota mouse model.

Stromberg ZR, Van Goor A, Redweik GAJ, Brand MJW, Wannemuehler MJ, Mellata M.

Dis Model Mech. 2018 Sep 28. pii: dmm.035063. doi: 10.1242/dmm.035063. [Epub ahead of print]

2.

Intranasal delivery of influenza antigen by nanoparticles, but not NKT-cell adjuvant differentially induces the expression of B-cell activation factors in mice and swine.

Renu S, Dhakal S, Kim E, Goodman J, Lakshmanappa YS, Wannemuehler MJ, Narasimhan B, Boyaka PN, Renukaradhya GJ.

Cell Immunol. 2018 Jul;329:27-30. doi: 10.1016/j.cellimm.2018.04.005. Epub 2018 Apr 11.

PMID:
29665972
3.

Room Temperature Stable PspA-Based Nanovaccine Induces Protective Immunity.

Wagner-Muñiz DA, Haughney SL, Kelly SM, Wannemuehler MJ, Narasimhan B.

Front Immunol. 2018 Mar 2;9:325. doi: 10.3389/fimmu.2018.00325. eCollection 2018.

4.

Emerging trends in the immunotherapy of pancreatic cancer.

Banerjee K, Kumar S, Ross KA, Gautam S, Poelaert B, Nasser MW, Aithal A, Bhatia R, Wannemuehler MJ, Narasimhan B, Solheim JC, Batra SK, Jain M.

Cancer Lett. 2018 Mar 28;417:35-46. doi: 10.1016/j.canlet.2017.12.012. Epub 2017 Dec 12.

PMID:
29242097
5.

Functionalization promotes pathogen-mimicking characteristics of polyanhydride nanoparticle adjuvants.

Phanse Y, Carrillo-Conde BR, Ramer-Tait AE, Roychoudhury R, Broderick S, Pohl N, Rajan K, Narasimhan B, Wannemuehler MJ, Bellaire BH.

J Biomed Mater Res A. 2017 Oct;105(10):2762-2771. doi: 10.1002/jbm.a.36128. Epub 2017 Jul 6.

PMID:
28556563
6.

Polyanhydride nanovaccine against swine influenza virus in pigs.

Dhakal S, Goodman J, Bondra K, Lakshmanappa YS, Hiremath J, Shyu DL, Ouyang K, Kang KI, Krakowka S, Wannemuehler MJ, Won Lee C, Narasimhan B, Renukaradhya GJ.

Vaccine. 2017 Feb 22;35(8):1124-1131. doi: 10.1016/j.vaccine.2017.01.019. Epub 2017 Jan 20.

PMID:
28117173
7.

Reply.

Ince MN, Blazar BR, Edmond MB, Tricot G, Wannemuehler MJ.

Inflamm Bowel Dis. 2016 Aug;22(8):E27-8. doi: 10.1097/MIB.0000000000000861. No abstract available.

8.

Cellular Internalization Mechanisms of Polyanhydride Particles: Implications for Rational Design of Drug Delivery Vehicles.

Phanse Y, Lueth P, Ramer-Tait AE, Carrillo-Conde BR, Wannemuehler MJ, Narasihan B, Bellaire BH.

J Biomed Nanotechnol. 2016 Jul;12(7):1544-52.

PMID:
29337493
9.

Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a(-/-) mice.

Haarberg KM, Wymore Brand MJ, Overstreet AM, Hauck CC, Murphy PA, Hostetter JM, Ramer-Tait AE, Wannemuehler MJ.

World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):223-37. doi: 10.4292/wjgpt.v6.i4.223.

10.

Understanding Luminal Microorganisms and Their Potential Effectiveness in Treating Intestinal Inflammation.

Ince MN, Blazar BR, Edmond MB, Tricot G, Wannemuehler MJ.

Inflamm Bowel Dis. 2016 Jan;22(1):194-201. doi: 10.1097/MIB.0000000000000599. Review.

11.

The Altered Schaedler Flora: Continued Applications of a Defined Murine Microbial Community.

Wymore Brand M, Wannemuehler MJ, Phillips GJ, Proctor A, Overstreet AM, Jergens AE, Orcutt RP, Fox JG.

ILAR J. 2015;56(2):169-78. doi: 10.1093/ilar/ilv012. Review.

12.

Attenuation of Colitis by Serum-Derived Bovine Immunoglobulin/Protein Isolate in a Defined Microbiota Mouse Model.

Henderson AL, Brand MW, Darling RJ, Maas KJ, Detzel CJ, Hostetter J, Wannemuehler MJ, Weaver EM.

Dig Dis Sci. 2015 Nov;60(11):3293-303. doi: 10.1007/s10620-015-3726-5. Epub 2015 May 31.

13.

Vaccine technologies against avian influenza: current approaches and new directions.

Ross KA, Huntimer LM, Vela Ramirez JE, Adams JR, Carpenter SL, Kohut ML, Bronich T, Webby R, Legge KL, Mallapragadal SK, Wannemuehler MJ, Narasimhan B.

J Biomed Nanotechnol. 2014 Sep;10(9):2261-94. Review.

PMID:
25992457
14.

Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity.

Ross KA, Loyd H, Wu W, Huntimer L, Ahmed S, Sambol A, Broderick S, Flickinger Z, Rajan K, Bronich T, Mallapragada S, Wannemuehler MJ, Carpenter S, Narasimhan B.

Int J Nanomedicine. 2014 Dec 30;10:229-43. doi: 10.2147/IJN.S72264. eCollection 2015.

15.

Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles.

Vela-Ramirez JE, Goodman JT, Boggiatto PM, Roychoudhury R, Pohl NL, Hostetter JM, Wannemuehler MJ, Narasimhan B.

AAPS J. 2015 Jan;17(1):256-67. doi: 10.1208/s12248-014-9699-z. Epub 2014 Nov 25.

16.

Pulmonary biodistribution and cellular uptake of intranasally administered monodisperse particles.

Brenza TM, Petersen LK, Zhang Y, Huntimer LM, Ramer-Tait AE, Hostetter JM, Wannemuehler MJ, Narasimhan B.

Pharm Res. 2015 Apr;32(4):1368-82. doi: 10.1007/s11095-014-1540-y. Epub 2014 Oct 9.

PMID:
25297714
17.

Effect of nanovaccine chemistry on humoral immune response kinetics and maturation.

Haughney SL, Ross KA, Boggiatto PM, Wannemuehler MJ, Narasimhan B.

Nanoscale. 2014 Nov 21;6(22):13770-8. doi: 10.1039/c4nr03724c.

PMID:
25285425
18.

Draft genome sequences of the altered schaedler flora, a defined bacterial community from gnotobiotic mice.

Wannemuehler MJ, Overstreet AM, Ward DV, Phillips GJ.

Genome Announc. 2014 Apr 10;2(2). pii: e00287-14. doi: 10.1128/genomeA.00287-14.

19.

Salmonella enterica serovar Typhimurium-infected pigs with different shedding levels exhibit distinct clinical, peripheral cytokine and transcriptomic immune response phenotypes.

Knetter SM, Bearson SM, Huang TH, Kurkiewicz D, Schroyen M, Nettleton D, Berman D, Cohen V, Lunney JK, Ramer-Tait AE, Wannemuehler MJ, Tuggle CK.

Innate Immun. 2015 Apr;21(3):227-41. doi: 10.1177/1753425914525812. Epub 2014 Mar 14.

PMID:
24632525
20.

Lung deposition and cellular uptake behavior of pathogen-mimicking nanovaccines in the first 48 hours.

Ross KA, Haughney SL, Petersen LK, Boggiatto P, Wannemuehler MJ, Narasimhan B.

Adv Healthc Mater. 2014 Jul;3(7):1071-7. doi: 10.1002/adhm.201300525. Epub 2014 Feb 12.

PMID:
24520022
21.

Structural and antigenic stability of H5N1 hemagglutinin trimer upon release from polyanhydride nanoparticles.

Ross KA, Loyd H, Wu W, Huntimer L, Wannemuehler MJ, Carpenter S, Narasimhan B.

J Biomed Mater Res A. 2014 Nov;102(11):4161-8. doi: 10.1002/jbm.a.35086. Epub 2014 Feb 4.

PMID:
24443139
22.

A systems approach to designing next generation vaccines: combining α-galactose modified antigens with nanoparticle platforms.

Phanse Y, Carrillo-Conde BR, Ramer-Tait AE, Broderick S, Kong CS, Rajan K, Flick R, Mandell RB, Narasimhan B, Wannemuehler MJ.

Sci Rep. 2014 Jan 20;4:3775. doi: 10.1038/srep03775.

23.

Organic barn dust extract exposure impairs porcine macrophage function in vitro: implications for respiratory health.

Knetter SM, Tuggle CK, Wannemuehler MJ, Ramer-Tait AE.

Vet Immunol Immunopathol. 2014 Jan 15;157(1-2):20-30. doi: 10.1016/j.vetimm.2013.10.019. Epub 2013 Nov 5.

PMID:
24275039
24.

Combinatorial evaluation of in vivo distribution of polyanhydride particle-based platforms for vaccine delivery.

Petersen LK, Huntimer L, Walz K, Ramer-Tait A, Wannemuehler MJ, Narasimhan B.

Int J Nanomedicine. 2013;8:2213-25. doi: 10.2147/IJN.S45317. Epub 2013 Jun 18.

25.

Functionalization of polyanhydride microparticles with di-mannose influences uptake by and intracellular fate within dendritic cells.

Phanse Y, Carrillo-Conde BR, Ramer-Tait AE, Roychoudhury R, Pohl NL, Narasimhan B, Wannemuehler MJ, Bellaire BH.

Acta Biomater. 2013 Nov;9(11):8902-9. doi: 10.1016/j.actbio.2013.06.024. Epub 2013 Jun 22.

PMID:
23796408
26.

Retention of structure, antigenicity, and biological function of pneumococcal surface protein A (PspA) released from polyanhydride nanoparticles.

Haughney SL, Petersen LK, Schoofs AD, Ramer-Tait AE, King JD, Briles DE, Wannemuehler MJ, Narasimhan B.

Acta Biomater. 2013 Sep;9(9):8262-71. doi: 10.1016/j.actbio.2013.06.006. Epub 2013 Jun 14.

27.

Evaluation of biocompatibility and administration site reactogenicity of polyanhydride-particle-based platform for vaccine delivery.

Huntimer L, Ramer-Tait AE, Petersen LK, Ross KA, Walz KA, Wang C, Hostetter J, Narasimhan B, Wannemuehler MJ.

Adv Healthc Mater. 2013 Feb;2(2):369-78. doi: 10.1002/adhm.201200181. Epub 2012 Sep 26.

PMID:
23184561
28.

Single immunization with a suboptimal antigen dose encapsulated into polyanhydride microparticles promotes high titer and avid antibody responses.

Huntimer L, Wilson Welder JH, Ross K, Carrillo-Conde B, Pruisner L, Wang C, Narasimhan B, Wannemuehler MJ, Ramer-Tait AE.

J Biomed Mater Res B Appl Biomater. 2013 Jan;101(1):91-8. doi: 10.1002/jbm.b.32820. Epub 2012 Nov 10.

PMID:
23143744
29.

Gene expression in intestinal mucosal biopsy specimens obtained from dogs with chronic enteropathy.

Wilke VL, Nettleton D, Wymore MJ, Gallup JM, Demirkale CY, Ackermann MR, Tuggle CK, Ramer-Tait AE, Wannemuehler MJ, Jergens AE.

Am J Vet Res. 2012 Aug;73(8):1219-29. doi: 10.2460/ajvr.73.8.1219.

PMID:
22849683
30.

Analyzing cellular internalization of nanoparticles and bacteria by multi-spectral imaging flow cytometry.

Phanse Y, Ramer-Tait AE, Friend SL, Carrillo-Conde B, Lueth P, Oster CJ, Phillips GJ, Narasimhan B, Wannemuehler MJ, Bellaire BH.

J Vis Exp. 2012 Jun 8;(64):e3884. doi: 10.3791/3884.

31.

Chemistry-dependent adsorption of serum proteins onto polyanhydride microparticles differentially influences dendritic cell uptake and activation.

Carrillo-Conde BR, Ramer-Tait AE, Wannemuehler MJ, Narasimhan B.

Acta Biomater. 2012 Oct;8(10):3618-28. doi: 10.1016/j.actbio.2012.06.001. Epub 2012 Jun 8.

32.

Tailoring the immune response by targeting C-type lectin receptors on alveolar macrophages using "pathogen-like" amphiphilic polyanhydride nanoparticles.

Chavez-Santoscoy AV, Roychoudhury R, Pohl NL, Wannemuehler MJ, Narasimhan B, Ramer-Tait AE.

Biomaterials. 2012 Jun;33(18):4762-72. doi: 10.1016/j.biomaterials.2012.03.027. Epub 2012 Apr 1.

33.

Amphiphilic polyanhydride nanoparticles stabilize Bacillus anthracis protective antigen.

Petersen LK, Phanse Y, Ramer-Tait AE, Wannemuehler MJ, Narasimhan B.

Mol Pharm. 2012 Apr 2;9(4):874-82. doi: 10.1021/mp2004059. Epub 2012 Mar 20.

34.

Rational design of pathogen-mimicking amphiphilic materials as nanoadjuvants.

Ulery BD, Petersen LK, Phanse Y, Kong CS, Broderick SR, Kumar D, Ramer-Tait AE, Carrillo-Conde B, Rajan K, Wannemuehler MJ, Bellaire BH, Metzger DW, Narasimhan B.

Sci Rep. 2011;1:198. doi: 10.1038/srep00198. Epub 2011 Dec 16.

35.

Distinct peripheral blood RNA responses to Salmonella in pigs differing in Salmonella shedding levels: intersection of IFNG, TLR and miRNA pathways.

Huang TH, Uthe JJ, Bearson SM, Demirkale CY, Nettleton D, Knetter S, Christian C, Ramer-Tait AE, Wannemuehler MJ, Tuggle CK.

PLoS One. 2011;6(12):e28768. doi: 10.1371/journal.pone.0028768. Epub 2011 Dec 12.

36.

Mannose-functionalized "pathogen-like" polyanhydride nanoparticles target C-type lectin receptors on dendritic cells.

Carrillo-Conde B, Song EH, Chavez-Santoscoy A, Phanse Y, Ramer-Tait AE, Pohl NL, Wannemuehler MJ, Bellaire BH, Narasimhan B.

Mol Pharm. 2011 Oct 3;8(5):1877-86. doi: 10.1021/mp200213r. Epub 2011 Sep 13.

37.

Activation of innate immune responses in a pathogen-mimicking manner by amphiphilic polyanhydride nanoparticle adjuvants.

Petersen LK, Ramer-Tait AE, Broderick SR, Kong CS, Ulery BD, Rajan K, Wannemuehler MJ, Narasimhan B.

Biomaterials. 2011 Oct;32(28):6815-22. doi: 10.1016/j.biomaterials.2011.05.063. Epub 2011 Jun 24.

PMID:
21703679
38.

Helicobacter bilis colonization enhances susceptibility to Typhlocolitis following an inflammatory trigger.

Liu Z, Ramer-Tait AE, Henderson AL, Demirkale CY, Nettleton D, Wang C, Hostetter JM, Jergens AE, Wannemuehler MJ.

Dig Dis Sci. 2011 Oct;56(10):2838-48. doi: 10.1007/s10620-011-1701-3. Epub 2011 Apr 19.

PMID:
21503679
39.

Polyanhydride microparticles enhance dendritic cell antigen presentation and activation.

Torres MP, Wilson-Welder JH, Lopac SK, Phanse Y, Carrillo-Conde B, Ramer-Tait AE, Bellaire BH, Wannemuehler MJ, Narasimhan B.

Acta Biomater. 2011 Jul;7(7):2857-64. doi: 10.1016/j.actbio.2011.03.023. Epub 2011 Mar 23.

40.

Design of a protective single-dose intranasal nanoparticle-based vaccine platform for respiratory infectious diseases.

Ulery BD, Kumar D, Ramer-Tait AE, Metzger DW, Wannemuehler MJ, Narasimhan B.

PLoS One. 2011 Mar 3;6(3):e17642. doi: 10.1371/journal.pone.0017642.

41.

Persistent enteric mycobacterial infection enhances sensitivity to acute mucosal injury.

Johnson CS, Wannemuehler MJ, Hostetter JM.

Exp Biol Med (Maywood). 2011 Jan;236(1):36-43. doi: 10.1258/ebm.2010.010152.

PMID:
21239734
42.

Unique genome-wide transcriptome profiles of chicken macrophages exposed to Salmonella-derived endotoxin.

Ciraci C, Tuggle CK, Wannemuehler MJ, Nettleton D, Lamont SJ.

BMC Genomics. 2010 Oct 8;11:545. doi: 10.1186/1471-2164-11-545.

43.

Prophylactic treatment with Hypoxis hemerocallidea corm (African potato) methanolic extract ameliorates Brachyspira hyodysenteriae-induced murine typhlocolitis.

Liu Z, Wilson-Welder JH, Hostetter JM, Jergens AE, Wannemuehler MJ.

Exp Biol Med (Maywood). 2010 Feb;235(2):222-30. doi: 10.1258/ebm.2009.009269.

PMID:
20404038
44.

Encapsulation into amphiphilic polyanhydride microparticles stabilizes Yersinia pestis antigens.

Carrillo-Conde B, Schiltz E, Yu J, Chris Minion F, Phillips GJ, Wannemuehler MJ, Narasimhan B.

Acta Biomater. 2010 Aug;6(8):3110-9. doi: 10.1016/j.actbio.2010.01.040. Epub 2010 Feb 1.

PMID:
20123135
45.

Effect of polymer chemistry and fabrication method on protein release and stability from polyanhydride microspheres.

Lopac SK, Torres MP, Wilson-Welder JH, Wannemuehler MJ, Narasimhan B.

J Biomed Mater Res B Appl Biomater. 2009 Nov;91(2):938-47. doi: 10.1002/jbm.b.31478.

46.

The simultaneous effect of polymer chemistry and device geometry on the in vitro activation of murine dendritic cells.

Petersen LK, Xue L, Wannemuehler MJ, Rajan K, Narasimhan B.

Biomaterials. 2009 Oct;30(28):5131-42. doi: 10.1016/j.biomaterials.2009.05.069. Epub 2009 Jun 18.

PMID:
19539989
47.

High throughput cell-based screening of biodegradable polyanhydride libraries.

Adler AF, Petersen LK, Wilson JH, Torres MP, Thorstenson JB, Gardner SW, Mallapragada SK, Wannemuehler MJ, Narasimhan B.

Comb Chem High Throughput Screen. 2009 Aug;12(7):634-45. Epub 2009 Aug 1.

PMID:
19531023
48.

Mucosal gene expression profiles following the colonization of immunocompetent defined-flora C3H mice with Helicobacter bilis: a prelude to typhlocolitis.

Liu Z, Henderson AL, Nettleton D, Wilson-Welder JH, Hostetter JM, Ramer-Tait A, Jergens AE, Wannemuehler MJ.

Microbes Infect. 2009 Mar;11(3):374-83. doi: 10.1016/j.micinf.2008.12.013. Epub 2009 Jan 14.

PMID:
19397886
49.

Polymer chemistry influences monocytic uptake of polyanhydride nanospheres.

Ulery BD, Phanse Y, Sinha A, Wannemuehler MJ, Narasimhan B, Bellaire BH.

Pharm Res. 2009 Mar;26(3):683-90. doi: 10.1007/s11095-008-9760-7. Epub 2008 Nov 6.

PMID:
18987960
50.

Vaccine adjuvants: current challenges and future approaches.

Wilson-Welder JH, Torres MP, Kipper MJ, Mallapragada SK, Wannemuehler MJ, Narasimhan B.

J Pharm Sci. 2009 Apr;98(4):1278-316. doi: 10.1002/jps.21523. Review.

PMID:
18704954

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