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Items: 19


Opioids for breathlessness: psychological and neural factors influencing response variability.

Abdallah SJ, Faull OK, Wanigasekera V, Finnegan SL, Jensen D, Pattinson KTS.

Eur Respir J. 2019 Sep 19;54(3). pii: 1900275. doi: 10.1183/13993003.00275-2019. Print 2019 Sep. No abstract available.


Response to "Treating patients rather than their functional neuroimages" (Br J Anaesth 2018; 121: 969-71).

Wanigasekera V, Wartolowska K, Huggins JP, Duff EP, Vennart W, Whitlock M, Massat N, Pauer L, Rogers P, Hoggart B, Tracey I.

Br J Anaesth. 2019 Aug;123(2):e166-e171. doi: 10.1016/j.bja.2019.01.016. Epub 2019 Apr 9. No abstract available.


Sertraline or placebo in chronic breathlessness? Lessons from placebo research.

Pattinson K, Wanigasekera V.

Eur Respir J. 2019 Jan 17;53(1). pii: 1802225. doi: 10.1183/13993003.02225-2018. Print 2019 Jan. No abstract available.


Central Sensitization in Knee Osteoarthritis: Relating Presurgical Brainstem Neuroimaging and PainDETECT-Based Patient Stratification to Arthroplasty Outcome.

Soni A, Wanigasekera V, Mezue M, Cooper C, Javaid MK, Price AJ, Tracey I.

Arthritis Rheumatol. 2019 Apr;71(4):550-560. doi: 10.1002/art.40749. Epub 2019 Mar 6.


Disambiguating pharmacological mechanisms from placebo in neuropathic pain using functional neuroimaging.

Wanigasekera V, Wartolowska K, Huggins JP, Duff EP, Vennart W, Whitlock M, Massat N, Pauer L, Rogers P, Hoggart B, Tracey I.

Br J Anaesth. 2018 Feb;120(2):299-307. doi: 10.1016/j.bja.2017.11.064. Epub 2017 Nov 21.


Opioid suppression of conditioned anticipatory brain responses to breathlessness.

Hayen A, Wanigasekera V, Faull OK, Campbell SF, Garry PS, Raby SJM, Robertson J, Webster R, Wise RG, Herigstad M, Pattinson KTS.

Neuroimage. 2017 Apr 15;150:383-394. doi: 10.1016/j.neuroimage.2017.01.005. Epub 2017 Jan 3.


Disambiguating Pharmacodynamic Efficacy from Behavior with Neuroimaging: Implications for Analgesic Drug Development.

Wanigasekera V, Mezue M, Andersson J, Kong Y, Tracey I.

Anesthesiology. 2016 Jan;124(1):159-68. doi: 10.1097/ALN.0000000000000924.


Learning to identify CNS drug action and efficacy using multistudy fMRI data.

Duff EP, Vennart W, Wise RG, Howard MA, Harris RE, Lee M, Wartolowska K, Wanigasekera V, Wilson FJ, Whitlock M, Tracey I, Woolrich MW, Smith SM.

Sci Transl Med. 2015 Feb 11;7(274):274ra16. doi: 10.1126/scitranslmed.3008438.


Imaging opioid analgesia in the human brain and its potential relevance for understanding opioid use in chronic pain.

Lee MC, Wanigasekera V, Tracey I.

Neuropharmacology. 2014 Sep;84:123-30. doi: 10.1016/j.neuropharm.2013.06.035. Epub 2013 Jul 25. Review.


Amygdala activity contributes to the dissociative effect of cannabis on pain perception.

Lee MC, Ploner M, Wiech K, Bingel U, Wanigasekera V, Brooks J, Menon DK, Tracey I.

Pain. 2013 Jan;154(1):124-34. doi: 10.1016/j.pain.2012.09.017.


Baseline reward circuitry activity and trait reward responsiveness predict expression of opioid analgesia in healthy subjects.

Wanigasekera V, Lee MC, Rogers R, Kong Y, Leknes S, Andersson J, Tracey I.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17705-10. doi: 10.1073/pnas.1120201109. Epub 2012 Oct 8.


Stimulus site and modality dependence of functional activity within the human spinal cord.

Brooks JC, Kong Y, Lee MC, Warnaby CE, Wanigasekera V, Jenkinson M, Tracey I.

J Neurosci. 2012 May 2;32(18):6231-9. doi: 10.1523/JNEUROSCI.2543-11.2012.


Neural correlates of an injury-free model of central sensitization induced by opioid withdrawal in humans.

Wanigasekera V, Lee MC, Rogers R, Hu P, Tracey I.

J Neurosci. 2011 Feb 23;31(8):2835-42. doi: 10.1523/JNEUROSCI.5412-10.2011.


The effect of treatment expectation on drug efficacy: imaging the analgesic benefit of the opioid remifentanil.

Bingel U, Wanigasekera V, Wiech K, Ni Mhuircheartaigh R, Lee MC, Ploner M, Tracey I.

Sci Transl Med. 2011 Feb 16;3(70):70ra14. doi: 10.1126/scitranslmed.3001244.


The influence of preload on post-systolic shortening in ischaemic myocardium.

Dalmas S, Wanigasekera VA, Marsch SC, Ryder WA, Wong LS, Foëx P.

Eur J Anaesthesiol. 1995 Mar;12(2):127-33.


Effects of propofol and thiopentone, and benzodiazepine premedication on heart rate variability measured by spectral analysis.

Howell SJ, Wanigasekera V, Young JD, Gavaghan D, Sear JW, Garrard CS.

Br J Anaesth. 1995 Feb;74(2):168-73.


Post-ischemic diastolic dysfunction.

Marsch SC, Dalmas S, Philbin DM, Wanigasekera VA, Ryder WA, Wong LS, Foëx P.

J Cardiothorac Vasc Anesth. 1994 Dec;8(6):611-7.


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