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Items: 9

1.

Characterization of protein therapeutics by mass spectrometry: recent developments and future directions.

Chen G, Warrack BM, Goodenough AK, Wei H, Wang-Iverson DB, Tymiak AA.

Drug Discov Today. 2011 Jan;16(1-2):58-64. doi: 10.1016/j.drudis.2010.11.003. Epub 2010 Nov 18. Review.

PMID:
21093608
2.

A tris (2-carboxyethyl) phosphine (TCEP) related cleavage on cysteine-containing proteins.

Liu P, O'Mara BW, Warrack BM, Wu W, Huang Y, Zhang Y, Zhao R, Lin M, Ackerman MS, Hocknell PK, Chen G, Tao L, Rieble S, Wang J, Wang-Iverson DB, Tymiak AA, Grace MJ, Russell RJ.

J Am Soc Mass Spectrom. 2010 May;21(5):837-44. doi: 10.1016/j.jasms.2010.01.016. Epub 2010 Jan 28.

3.

Periodic, partial inhibition of IkappaB Kinase beta-mediated signaling yields therapeutic benefit in preclinical models of rheumatoid arthritis.

Gillooly KM, Pattoli MA, Taylor TL, Chen L, Cheng L, Gregor KR, Whitney GS, Susulic V, Watterson SH, Kempson J, Pitts WJ, Booth-Lute H, Yang G, Davies P, Kukral DW, Strnad J, McIntyre KW, Darienzo CJ, Salter-Cid L, Yang Z, Wang-Iverson DB, Burke JR.

J Pharmacol Exp Ther. 2009 Nov;331(2):349-60. doi: 10.1124/jpet.109.156018. Epub 2009 Aug 3.

PMID:
19652024
4.

Development and implementation of a stereoselective normal-phase liquid chromatography-tandem mass spectrometry method for the determination of intrinsic metabolic clearance in human liver microsomes.

Zhang Y, Caporuscio C, Dai J, Witkusa M, Rose A, Santella J, D'Arienzo C, Wang-Iverson DB, Tymiak AA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 1;875(1):154-60. doi: 10.1016/j.jchromb.2008.07.034.

PMID:
18722827
5.

Simulated moving columns technique for enantioselective supercritical fluid chromatography.

Zhang Y, Dai J, Wang-Iverson DB, Tymiak AA.

Chirality. 2007 Sep;19(9):683-92.

PMID:
17487890
6.

Enantioselective chromatography in drug discovery.

Zhang Y, Wu DR, Wang-Iverson DB, Tymiak AA.

Drug Discov Today. 2005 Apr 15;10(8):571-7. Review.

PMID:
15837600
7.
8.

Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.

Das J, Kimball SD, Hall SE, Han WC, Iwanowicz E, Lin J, Moquin RV, Reid JA, Sack JS, Malley MF, Chang CY, Chong S, Wang-Iverson DB, Roberts DG, Seiler SM, Schumacher WA, Ogletree ML.

Bioorg Med Chem Lett. 2002 Jan 7;12(1):45-9.

PMID:
11738570
9.

The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity.

Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann WH.

Endocrinology. 2000 Sep;141(9):3057-64.

PMID:
10965874

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