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Microstructurally Motivated Constitutive Modeling of Heart Failure Mechanics.

Hasaballa AI, Wang VY, Sands GB, Wilson AJ, Young AA, LeGrice IJ, Nash MP.

Biophys J. 2019 Oct 7. pii: S0006-3495(19)30825-2. doi: 10.1016/j.bpj.2019.09.038. [Epub ahead of print]


Mechanical effects of MitraClip on leaflet stress and myocardial strain in functional mitral regurgitation - A finite element modeling study.

Zhang Y, Wang VY, Morgan AE, Kim J, Handschumacher MD, Moskowitz CS, Levine RA, Ge L, Guccione JM, Weinsaft JW, Ratcliffe MB.

PLoS One. 2019 Oct 10;14(10):e0223472. doi: 10.1371/journal.pone.0223472. eCollection 2019.


Genome reading by the NF-κB transcription factors.

Mulero MC, Wang VY, Huxford T, Ghosh G.

Nucleic Acids Res. 2019 Nov 4;47(19):9967-9989. doi: 10.1093/nar/gkz739.


Arabidopsis DXO1 links RNA turnover and chloroplast function independently of its enzymatic activity.

Kwasnik A, Wang VY, Krzyszton M, Gozdek A, Zakrzewska-Placzek M, Stepniak K, Poznanski J, Tong L, Kufel J.

Nucleic Acids Res. 2019 May 21;47(9):4751-4764. doi: 10.1093/nar/gkz100. Erratum in: Nucleic Acids Res. 2019 May 21;47(9):4910.


Arabidopsis DXO1 links RNA turnover and chloroplast function independently of its enzymatic activity.

Kwasnik A, Wang VY, Krzyszton M, Gozdek A, Zakrzewska-Placzek M, Stepniak K, Poznanski J, Tong L, Kufel J.

Nucleic Acids Res. 2019 May 21;47(9):4910. doi: 10.1093/nar/gkz257. No abstract available.


A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles.

Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, Blau HM, Wu JC.

Cell Stem Cell. 2019 May 2;24(5):802-811.e5. doi: 10.1016/j.stem.2019.02.015. Epub 2019 Mar 14.


Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells.

Meng Y, Ren Z, Xu F, Zhou X, Song C, Wang VY, Liu W, Lu L, Thomson JA, Chen G.

Stem Cell Reports. 2018 Dec 11;11(6):1347-1356. doi: 10.1016/j.stemcr.2018.10.023. Epub 2018 Nov 29.


Left Ventricular Diastolic Myocardial Stiffness and End-Diastolic Myofibre Stress in Human Heart Failure Using Personalised Biomechanical Analysis.

Wang ZJ, Wang VY, Bradley CP, Nash MP, Young AA, Cao JJ.

J Cardiovasc Transl Res. 2018 Aug;11(4):346-356. doi: 10.1007/s12265-018-9816-y. Epub 2018 Jul 11.


Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit.

Mulero MC, Shahabi S, Ko MS, Schiffer JM, Huang DB, Wang VY, Amaro RE, Huxford T, Ghosh G.

Biochemistry. 2018 May 22;57(20):2943-2957. doi: 10.1021/acs.biochem.8b00158. Epub 2018 May 10.


DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor κB are not correlated.

Mulero MC, Huang DB, Nguyen HT, Wang VY, Li Y, Biswas T, Ghosh G.

J Biol Chem. 2017 Nov 17;292(46):18821-18830. doi: 10.1074/jbc.M117.813980. Epub 2017 Sep 21.


Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity.

Wang VY, Li Y, Kim D, Zhong X, Du Q, Ghassemian M, Ghosh G.

Mol Cell. 2017 Aug 3;67(3):484-497.e5. doi: 10.1016/j.molcel.2017.06.011. Epub 2017 Jul 6.


Neurosurgery concepts: Key perspectives on endoscopic versus microscopic resection for pituitary adenomas, surgical decision-making in tuberculum sellae meningiomas, optic nerve mobilization during resection of craniopharyngiomas, and evaluation of headache and quality of life after endoscopic transphenoidal surgery for pituitary adenomas.

Germanwala AV, Hofler R, Lagman C, Chung LK, Khalessi AA, Zada G, Smith ZA, Dahdaleh NS, Bohnen AM, Cho JM, Colen CB, Duckworth E, Kan P, Lam S, Kim CY, Li G, Lim M, Sherman JH, Wang VY, Yang I.

Surg Neurol Int. 2017 Apr 5;8:52. doi: 10.4103/sni.sni_17_17. eCollection 2017. No abstract available.


Neurosurgery concepts: Key perspectives on imaging characteristics of spinal metastases, surgery for low back pain, anesthesia for disc surgery, and laminectomy versus laminectomy and fusion for lumbar spondylolisthesis.

Lagman C, Chung LK, Macyszyn L, Choy W, Smith ZA, Dahdaleh NS, Bohnen AM, Cho JM, Colen CB, Duckworth E, Germanwala AV, Kan P, Khalessi AA, Kim CY, Lam S, Li G, Lim M, Sherman JH, Wang VY, Zada G, Yang I.

Surg Neurol Int. 2017 Jan 19;8:9. doi: 10.4103/2152-7806.198736. eCollection 2017. No abstract available.


Increased cardiac work provides a link between systemic hypertension and heart failure.

Wilson AJ, Wang VY, Sands GB, Young AA, Nash MP, LeGrice IJ.

Physiol Rep. 2017 Jan;5(1). pii: e13104. doi: 10.14814/phy2.13104.


Image-Based Investigation of Human in Vivo Myofibre Strain.

Wang VY, Casta C, Zhu YM, Cowan BR, Croisille P, Young AA, Clarysse P, Nash MP.

IEEE Trans Med Imaging. 2016 Nov;35(11):2486-2496. Epub 2016 Jun 14.


Breast cancer molecular subtypes: from TNBC to QNBC.

Hon JD, Singh B, Sahin A, Du G, Wang J, Wang VY, Deng FM, Zhang DY, Monaco ME, Lee P.

Am J Cancer Res. 2016 Sep 1;6(9):1864-1872. eCollection 2016. Review.


The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100.

Fusco AJ, Mazumder A, Wang VY, Tao Z, Ware C, Ghosh G.

Sci Signal. 2016 Sep 27;9(447):ra96. doi: 10.1126/scisignal.aad9413.


Three-dimensional, virtual reality vestibular rehabilitation for chronic imbalance problem caused by Ménière's disease: a pilot study<sup/>.

Hsu SY, Fang TY, Yeh SC, Su MC, Wang PC, Wang VY.

Disabil Rehabil. 2017 Aug;39(16):1601-1606. doi: 10.1080/09638288.2016.1203027. Epub 2016 Jul 15.


Examining the effects of an interprofessional crew resource management training intervention on perceptions of patient safety.

Wu WT, Wu YL, Hou SM, Kang CM, Huang CH, Huang YJ, Wang VY, Wang PC.

J Interprof Care. 2016 Jul;30(4):536-8. doi: 10.1080/13561820.2016.1181612.


Multiphysics and multiscale modelling, data-model fusion and integration of organ physiology in the clinic: ventricular cardiac mechanics.

Chabiniok R, Wang VY, Hadjicharalambous M, Asner L, Lee J, Sermesant M, Kuhl E, Young AA, Moireau P, Nash MP, Chapelle D, Nordsletten DA.

Interface Focus. 2016 Apr 6;6(2):20150083. doi: 10.1098/rsfs.2015.0083. Review.


P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.

Sansó M, Levin RS, Lipp JJ, Wang VY, Greifenberg AK, Quezada EM, Ali A, Ghosh A, Larochelle S, Rana TM, Geyer M, Tong L, Shokat KM, Fisher RP.

Genes Dev. 2016 Jan 1;30(1):117-31. doi: 10.1101/gad.269589.115.


Image-Based Predictive Modeling of Heart Mechanics.

Wang VY, Nielsen PM, Nash MP.

Annu Rev Biomed Eng. 2015;17:351-83. doi: 10.1146/annurev-bioeng-071114-040609. Review.


DNA methylation screening of primary prostate tumors identifies SRD5A2 and CYP11A1 as candidate markers for assessing risk of biochemical recurrence.

Horning AM, Awe JA, Wang CM, Liu J, Lai Z, Wang VY, Jadhav RR, Louie AD, Lin CL, Kroczak T, Chen Y, Jin VX, Abboud-Werner SL, Leach RJ, Hernandez J, Thompson IM, Saranchuk J, Drachenberg D, Chen CL, Mai S, Huang TH.

Prostate. 2015 Nov;75(15):1790-801. doi: 10.1002/pros.23052. Epub 2015 Sep 1.


Neurosurgery Concepts: Key perspectives on Traumatic Brain Injury, New Treatments for Glioblastoma, Hemicraniectomy for Extensive Middle-Cerebral-Artery Stroke, Minimally Invasive Spine Surgery and Lumbar Epidural Injections for Radiculopathy.

Cho JM, Colen CB, Li G, Wang VY, Dahdaleh N, Choy W, Yang I, Smith ZA.

Surg Neurol Int. 2015 Jun 8;6:98. doi: 10.4103/2152-7806.158374. eCollection 2015. No abstract available.


Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes.

Wang VY, Jiao X, Kiledjian M, Tong L.

Nucleic Acids Res. 2015 Jul 27;43(13):6596-606. doi: 10.1093/nar/gkv620. Epub 2015 Jun 22.


Accuracy of body weight perception and obesity among Chinese Americans.

Liu S, Fu MR, Hu SH, Wang VY, Crupi R, Qiu JM, Cleland C, D'Eramo Melkus G.

Obes Res Clin Pract. 2016 Sep;10 Suppl 1:S48-S56. doi: 10.1016/j.orcp.2015.04.004. Epub 2015 Apr 30.


Neurosurgery concepts: Key perspectives on dendritic cell vaccines, metastatic tumor treatment, and radiosurgery.

Li G, Sherman JH, Cho JM, Lim M, Khalessi AA, Colen CB, Kim CY, Wang VY, Zada G, Smith ZA, Yang I.

Surg Neurol Int. 2015 Jan 14;6:6. doi: 10.4103/2152-7806.149389. eCollection 2015.


Image-based computational cardiology: from data to understanding.

Wang L, Wang VY, Zhang H.

Comput Math Methods Med. 2014;2014:120960. doi: 10.1155/2014/120960. Epub 2014 Jun 1. No abstract available.


Neurosurgery concepts: Key perspectives on regulatory proteins, management of ossification of the posterior longitudinal ligament, and radiosurgery for intracranial lesions.

Sherman JH, Smith ZA, Cho JM, Lim M, Colen CB, Kim CY, Wang VY, Zada G, Li G, Yang I.

Surg Neurol Int. 2013 Mar 25;4:35. doi: 10.4103/2152-7806.109525. Print 2013. No abstract available.


The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements.

Wang VY, Huang W, Asagiri M, Spann N, Hoffmann A, Glass C, Ghosh G.

Cell Rep. 2012 Oct 25;2(4):824-39. doi: 10.1016/j.celrep.2012.08.042. Epub 2012 Oct 11.


Perspectives on key articles in neurosurgery.

Lim M, Sherman JH, Wang VY, Smith ZA, Cho JM, Colen CB, Kim CY, Zada G, Li G, Yang I.

Surg Neurol Int. 2012;3:58. doi: 10.4103/2152-7806.96869. Epub 2012 May 31. No abstract available.


NF-κB regulation: lessons from structures.

Ghosh G, Wang VY, Huang DB, Fusco A.

Immunol Rev. 2012 Mar;246(1):36-58. doi: 10.1111/j.1600-065X.2012.01097.x. Review.


Neurosurgery concepts.

Yang I, Cho JM, Colen CB, Li G, Lim M, Sherman JH, Wang VY.

Surg Neurol Int. 2011;2:173. doi: 10.4103/2152-7806.90444. Epub 2011 Nov 30. No abstract available.


Spine and spinal cord emergencies: vascular and infectious causes.

Wang VY, Chou D, Chin C.

Neuroimaging Clin N Am. 2010 Nov;20(4):639-50. doi: 10.1016/j.nic.2010.07.006. Review.


Electromechanical wavebreak in a model of the human left ventricle.

Keldermann RH, Nash MP, Gelderblom H, Wang VY, Panfilov AV.

Am J Physiol Heart Circ Physiol. 2010 Jul;299(1):H134-43. doi: 10.1152/ajpheart.00862.2009. Epub 2010 Apr 16.


Free-hand thoracic pedicle screws placed by neurosurgery residents: a CT analysis.

Wang VY, Chin CT, Lu DC, Smith JS, Chou D.

Eur Spine J. 2010 May;19(5):821-7. doi: 10.1007/s00586-010-1293-1. Epub 2010 Feb 5.


Pedicle subtraction osteotomies for the correction of post-traumatic thoracolumbar kyphosis.

Chou D, Wang VY, Storm PB.

J Clin Neurosci. 2010 Jan;17(1):113-7. doi: 10.1016/j.jocn.2009.03.038. Epub 2009 Nov 11.


Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditory nuclei.

Maricich SM, Xia A, Mathes EL, Wang VY, Oghalai JS, Fritzsch B, Zoghbi HY.

J Neurosci. 2009 Sep 9;29(36):11123-33. doi: 10.1523/JNEUROSCI.2232-09.2009.


Modelling passive diastolic mechanics with quantitative MRI of cardiac structure and function.

Wang VY, Lam HI, Ennis DB, Cowan BR, Young AA, Nash MP.

Med Image Anal. 2009 Oct;13(5):773-84. doi: 10.1016/ Epub 2009 Jul 16.


Transpedicular corpectomy with posterior expandable cage placement for L1 burst fracture.

Chou D, Wang VY, Gupta N.

J Clin Neurosci. 2009 Aug;16(8):1069-72. doi: 10.1016/j.jocn.2008.12.009. Epub 2009 May 20.


Primary dural repair during minimally invasive microdiscectomy using standard operating room instruments.

Chou D, Wang VY, Khan AS.

Neurosurgery. 2009 May;64(5 Suppl 2):356-8; discussion 358-9. doi: 10.1227/01.NEU.0000338942.11337.DA.


Reconstruction of C-1 lateral mass with titanium mesh cage after resection of an aneurysmal bone cyst of the atlas.

Wang VY, Deviren V, Ames CP.

J Neurosurg Spine. 2009 Feb;10(2):117-21. doi: 10.3171/2008.10.SPI08403.


Posterior transpedicular corpectomy and reconstruction of the axial vertebra for metastatic tumor.

Ames CP, Wang VY, Deviren V, Vrionis FD.

J Neurosurg Spine. 2009 Feb;10(2):111-6. doi: 10.3171/2008.11.SPI08445.


NF-kappaB p52:RelB heterodimer recognizes two classes of kappaB sites with two distinct modes.

Fusco AJ, Huang DB, Miller D, Wang VY, Vu D, Ghosh G.

EMBO Rep. 2009 Feb;10(2):152-9. doi: 10.1038/embor.2008.227. Epub 2008 Dec 19.


Passive ventricular mechanics modelling using MRI of structure and function.

Wang VY, Lam HI, Ennis DB, Young AA, Nash MP.

Med Image Comput Comput Assist Interv. 2008;11(Pt 2):814-21.


Vertebral column resection for rigid spinal deformity.

Smith JS, Wang VY, Ames CP.

Neurosurgery. 2008 Sep;63(3 Suppl):177-82. doi: 10.1227/01.NEU.0000320429.32113.85. Review.


Removal of ossified ligamentum flavum via a minimally invasive surgical approach.

Wang VY, Kanter AS, Mummaneni PV.

Neurosurg Focus. 2008;25(2):E7. doi: 10.3171/FOC/2008/25/8/E7.


A novel anterior technique for simultaneous single-stage anterior and posterior cervical release for fixed kyphosis.

Wang VY, Aryan H, Ames CP.

J Neurosurg Spine. 2008 Jun;8(6):594-9. doi: 10.3171/SPI/2008/8/6/594.


Stabilization of the atlantoaxial complex via C-1 lateral mass and C-2 pedicle screw fixation in a multicenter clinical experience in 102 patients: modification of the Harms and Goel techniques.

Aryan HE, Newman CB, Nottmeier EW, Acosta FL Jr, Wang VY, Ames CP.

J Neurosurg Spine. 2008 Mar;8(3):222-9. doi: 10.3171/SPI/2008/8/3/222.


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