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Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension.

Hilscher MB, Sehrawat T, Arab JP, Zeng Z, Gao J, Liu M, Kostallari E, Gao Y, Simonetto DA, Yaqoob U, Cao S, Revzin A, Beyder A, Wang RA, Kamath PS, Kubes P, Shah VH.

Gastroenterology. 2019 Jul;157(1):193-209.e9. doi: 10.1053/j.gastro.2019.03.013. Epub 2019 Mar 11.


Life history tradeoffs in humans: increased life expectancy with sperm count reduction.

Wang RA, Zheng PJ, Liu Y, Shang L.

Front Biosci (Landmark Ed). 2019 Mar 1;24:712-722.


Moderators of wellbeing interventions: Why do some people respond more positively than others?

Wang RAH, Nelson-Coffey SK, Layous K, Jacobs Bao K, Davis OSP, Haworth CMA.

PLoS One. 2017 Nov 6;12(11):e0187601. doi: 10.1371/journal.pone.0187601. eCollection 2017.


Combined use of alcohol in conventional chemical-induced mouse liver cancer model improves the simulation of clinical characteristics of human hepatocellular carcinoma.

Xin B, Cui Y, Wang Y, Wang L, Yin J, Zhang L, Pang H, Zhang H, Wang RA.

Oncol Lett. 2017 Oct;14(4):4722-4728. doi: 10.3892/ol.2017.6800. Epub 2017 Aug 23.


Social support and mental health in late adolescence are correlated for genetic, as well as environmental, reasons.

Wang RAH, Davis OSP, Wootton RE, Mottershaw A, Haworth CMA.

Sci Rep. 2017 Oct 12;7(1):13088. doi: 10.1038/s41598-017-13449-2.


Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow.

Hwa JJ, Beckouche N, Huang L, Kram Y, Lindskog H, Wang RA.

Sci Rep. 2017 Sep 20;7(1):11965. doi: 10.1038/s41598-017-12353-z.


Metastasis-Associated Protein 1 Deficiency Results in Compromised Pulmonary Alveolar Capillary Angiogenesis in Mice.

Qin JH, Ke ZY, Zhou Q, Wang L, Liang Y, Wang YM, Yang T, Gao X, Ye J, Kumar R, Wang RA.

Med Sci Monit. 2017 Aug 15;23:3932-3941.


Life history tradeoffs of pathogens and the treatment principle of antibiogenesis.

Wang RA.

Genes Dis. 2017 Jul 20;4(3):154-158. doi: 10.1016/j.gendis.2017.07.004. eCollection 2017 Sep. Review.


Genetic and environmental correlations between subjective wellbeing and experience of life events in adolescence.

Wootton RE, Davis OSP, Mottershaw AL, Wang RAH, Haworth CMA.

Eur Child Adolesc Psychiatry. 2017 Sep;26(9):1119-1127. doi: 10.1007/s00787-017-0997-8. Epub 2017 May 16.


Analysis of the Relationship between the Location of the Anterior Ethmoid Artery and Keros Classification.

Poteet PS, Cox MD, Wang RA, Fitzgerald RT, Kanaan A.

Otolaryngol Head Neck Surg. 2017 Aug;157(2):320-324. doi: 10.1177/0194599817696302. Epub 2017 Mar 28. Erratum in: Otolaryngol Head Neck Surg. 2017 Aug;157(2):351.


Exploring the Genetic Etiology of Trust in Adolescents: Combined Twin and DNA Analyses.

Wootton RE, Davis OS, Mottershaw AL, Wang RA, Haworth CM.

Twin Res Hum Genet. 2016 Dec;19(6):638-646.


Epithelial-mesenchymal transition as strategic microenvironment mimicry for cancer cell survival and immune escape?

Qin JH, Wang L, Li QL, Liang Y, Ke ZY, Wang RA.

Genes Dis. 2016 Nov 5;4(1):16-18. doi: 10.1016/j.gendis.2016.10.001. eCollection 2017 Mar.


Endothelial notch signaling is essential to prevent hepatic vascular malformations in mice.

Cuervo H, Nielsen CM, Simonetto DA, Ferrell L, Shah VH, Wang RA.

Hepatology. 2016 Oct;64(4):1302-1316. doi: 10.1002/hep.28713. Epub 2016 Aug 4.


Structure, expression and functions of MTA genes.

Kumar R, Wang RA.

Gene. 2016 May 15;582(2):112-21. doi: 10.1016/j.gene.2016.02.012. Epub 2016 Feb 9. Review.


Reasons for cancer metastasis: A holistic perspective.

Wang RA, Lu YY, Fan DM.

Mol Clin Oncol. 2015 Nov;3(6):1199-1202. Epub 2015 Aug 14.


Mouse Models of Cerebral Arteriovenous Malformation.

Nielsen CM, Huang L, Murphy PA, Lawton MT, Wang RA.

Stroke. 2016 Jan;47(1):293-300. doi: 10.1161/STROKEAHA.115.002869. Epub 2015 Sep 8. No abstract available.


The role of 5-HT2C receptors in touchscreen visual reversal learning in the rat: a cross-site study.

Alsiƶ J, Nilsson SR, Gastambide F, Wang RA, Dam SA, Mar AC, Tricklebank M, Robbins TW.

Psychopharmacology (Berl). 2015 Nov;232(21-22):4017-31. doi: 10.1007/s00213-015-3963-5. Epub 2015 May 26.


Low-level sequence variation in Toxoplasma gondii calcium-dependent protein kinases among different genotypes.

Wang JL, Zhang NZ, Huang SY, Xu Y, Wang RA, Zhu XQ.

Genet Mol Res. 2015 May 11;14(2):4949-56. doi: 10.4238/2015.May.11.28.


Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels.

Murphy PA, Kim TN, Huang L, Nielsen CM, Lawton MT, Adams RH, Schaffer CB, Wang RA.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):18007-12. doi: 10.1073/pnas.1415316111. Epub 2014 Dec 2.


MTA1--a stress response protein: a master regulator of gene expression and cancer cell behavior.

Wang RA.

Cancer Metastasis Rev. 2014 Dec;33(4):1001-9. doi: 10.1007/s10555-014-9525-1. Review.


Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice.

Nielsen CM, Cuervo H, Ding VW, Kong Y, Huang EJ, Wang RA.

Development. 2014 Oct;141(19):3782-92. doi: 10.1242/dev.108951. Epub 2014 Sep 10.


Characterization of the Toxoplasma gondii hsp60 gene sequences from different hosts and geographical locations.

Lu J, Zhou DH, Chen J, Zhang NZ, Wang RA, Weng YB, Zhu XQ.

Genet Mol Res. 2014 Aug 29;13(3):6906-11. doi: 10.4238/2014.August.29.13.


Sequence variation in Toxoplasma gondii rop17 gene among strains from different hosts and geographical locations.

Zhang NZ, Xu Y, Huang SY, Zhou DH, Wang RA, Zhu XQ.

ScientificWorldJournal. 2014;2014:349325. doi: 10.1155/2014/349325. Epub 2014 Jul 10.


Endothelial ephrin-B2 is essential for arterial vasodilation in mice.

Lin Y, Jiang W, Ng J, Jina A, Wang RA.

Microcirculation. 2014 Oct;21(7):578-86. doi: 10.1111/micc.12135.


Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals.

Lindskog H, Kim YH, Jelin EB, Kong Y, Guevara-Gallardo S, Kim TN, Wang RA.

Development. 2014 Mar;141(5):1120-8. doi: 10.1242/dev.101808.


Resistance to apoptosis should not be taken as a hallmark of cancer.

Wang RA, Li ZS, Yan QG, Bian XW, Ding YQ, Du X, Sun BC, Sun YT, Zhang XH.

Chin J Cancer. 2014 Feb;33(2):47-50. doi: 10.5732/cjc.013.10131. Epub 2013 Dec 24.


Central role of cellular senescence in TSLP-induced airway remodeling in asthma.

Wu J, Dong F, Wang RA, Wang J, Zhao J, Yang M, Gong W, Cui R, Dong L.

PLoS One. 2013 Oct 22;8(10):e77795. doi: 10.1371/journal.pone.0077795. eCollection 2013.


c-Myc-mediated epigenetic silencing of MicroRNA-101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma.

Wang L, Zhang X, Jia LT, Hu SJ, Zhao J, Yang JD, Wen WH, Wang Z, Wang T, Zhao J, Wang RA, Meng YL, Nie YZ, Dou KF, Chen SY, Yao LB, Fan DM, Zhang R, Yang AG.

Hepatology. 2014 May;59(5):1850-63. doi: 10.1002/hep.26720. Epub 2014 Mar 27.


Algorithm for the early diagnosis and treatment of patients with cross reactive immunologic material-negative classic infantile pompe disease: a step towards improving the efficacy of ERT.

Banugaria SG, Prater SN, Patel TT, Dearmey SM, Milleson C, Sheets KB, Bali DS, Rehder CW, Raiman JA, Wang RA, Labarthe F, Charrow J, Harmatz P, Chakraborty P, Rosenberg AS, Kishnani PS.

PLoS One. 2013 Jun 25;8(6):e67052. doi: 10.1371/journal.pone.0067052. Print 2013.


Invasive cancers are not necessarily from preformed in situ tumours - an alternative way of carcinogenesis from misplaced stem cells.

Wang RA, Li ZS, Zhang HZ, Zheng PJ, Li QL, Shi JG, Yan QG, Ye J, Wang JB, Guo Y, Huang XF, Yu YH.

J Cell Mol Med. 2013 Jul;17(7):921-6. doi: 10.1111/jcmm.12078. Epub 2013 Jun 7.


Notch4 is required for tumor onset and perfusion.

Costa MJ, Wu X, Cuervo H, Srinivasan R, Bechis SK, Cheang E, Marjanovic O, Gridley T, Cvetic CA, Wang RA.

Vasc Cell. 2013 Apr 20;5(1):7. doi: 10.1186/2045-824X-5-7.


MTA1 promotes STAT3 transcription and pulmonary metastasis in breast cancer.

Pakala SB, Rayala SK, Wang RA, Ohshiro K, Mudvari P, Reddy SD, Zheng Y, Pires R, Casimiro S, Pillai MR, Costa L, Kumar R.

Cancer Res. 2013 Jun 15;73(12):3761-70. doi: 10.1158/0008-5472.CAN-12-3998. Epub 2013 Apr 11.


Apoptosis drives cancer cells proliferate and metastasize.

Wang RA, Li QL, Li ZS, Zheng PJ, Zhang HZ, Huang XF, Chi SM, Yang AG, Cui R.

J Cell Mol Med. 2013 Jan;17(1):205-11. doi: 10.1111/j.1582-4934.2012.01663.x. Epub 2013 Jan 11.


TBX2 expression is regulated by PAX3 in the melanocyte lineage.

Liu F, Cao J, Lv J, Dong L, Pier E, Xu GX, Wang RA, Xu Z, Goding C, Cui R.

Pigment Cell Melanoma Res. 2013 Jan;26(1):67-77. doi: 10.1111/pcmr.12029. Epub 2012 Nov 21.


Expert consensus on the scheme of pathological diagnosis of primary liver cancer.

Cong WM, Hu XQ, Sun YT, Tan YS, Ji XL, Yun JP, Zhu HG, Guo H, Wang RA, Liu SX, Yin HL, Wang X, Li ZS, Ji Y; Chinese Society of Liver Cancer (CSLC); Chinese Society of Clinical Oncology (CSCO); Liver Cancer Group; Chinese Society of Hepatology; Chinese Pathological Group of Hepatobiliary Tumors and Liver Transplantation.

Chin Clin Oncol. 2012 Sep;1(1):12. doi: 10.3978/j.issn.2304-3865.2012.06.02. No abstract available.


[Expression and potential role of metastasis-associated protein 1 in the induced carcinogenesis of mouse liver].

Xin B, Wang XY, Li Y, Qin JH, Ma XJ, Yin JP, Wang RA.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2012 Aug;28(8):801-3. Chinese.


Line-scanning particle image velocimetry: an optical approach for quantifying a wide range of blood flow speeds in live animals.

Kim TN, Goodwill PW, Chen Y, Conolly SM, Schaffer CB, Liepmann D, Wang RA.

PLoS One. 2012;7(6):e38590. doi: 10.1371/journal.pone.0038590. Epub 2012 Jun 26.


Notch4 normalization reduces blood vessel size in arteriovenous malformations.

Murphy PA, Kim TN, Lu G, Bollen AW, Schaffer CB, Wang RA.

Sci Transl Med. 2012 Jan 18;4(117):117ra8. doi: 10.1126/scitranslmed.3002670.


FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription.

Dong L, Li Y, Cao J, Liu F, Pier E, Chen J, Xu Z, Chen C, Wang RA, Cui R.

Cell Death Differ. 2012 Apr;19(4):616-22. doi: 10.1038/cdd.2011.132. Epub 2011 Oct 14.


HER2 interacts with CD44 to up-regulate CXCR4 via epigenetic silencing of microRNA-139 in gastric cancer cells.

Bao W, Fu HJ, Xie QS, Wang L, Zhang R, Guo ZY, Zhao J, Meng YL, Ren XL, Wang T, Li Q, Jin BQ, Yao LB, Wang RA, Fan DM, Chen SY, Jia LT, Yang AG.

Gastroenterology. 2011 Dec;141(6):2076-2087.e6. doi: 10.1053/j.gastro.2011.08.050. Epub 2011 Sep 16.


[Observation on therapeutic alliance with UDCA and glucocorticoids in AIH-PBC overlap syndrome].

Zhu JY, Shi YQ, Han ZY, Jia G, Li ZS, Huang XF, Wang JH, Wang RA, Zhou XM, Han Y.

Zhonghua Gan Zang Bing Za Zhi. 2011 May;19(5):334-9. doi: 10.3760/cma.j.issn.1007-3418.2011.05.006. Chinese.


[Comparison between two diagnostic criteria for PBC-AIH overlap syndrome].

Zhu JY, Zhou XM, Wang JH, Wang RA, Huang XF, Han ZY, Chen Y, Han Y.

Zhonghua Gan Zang Bing Za Zhi. 2011 Feb;19(2):132-3. doi: 10.3760/cma.j.issn.1007-3418.2011.02.016. Chinese.


[A two-year follow-up study on the efficacy of ursodeoxycholic acid on primary biliary cirrhosis in different stages].

Zhu JY, Li ZS, Yan W, Wang JH, Zhou XM, Wang RA, Huang XF, Shi YQ, Dong XY, Han ZY, Han Y.

Zhonghua Gan Zang Bing Za Zhi. 2010 Oct;18(10):735-9. doi: 10.3760/cma.j.issn.1007-3418.2010.10.004. Chinese.


Inefficient skeletal muscle repair in inhibitor of differentiation knockout mice suggests a crucial role for BMP signaling during adult muscle regeneration.

Clever JL, Sakai Y, Wang RA, Schneider DB.

Am J Physiol Cell Physiol. 2010 May;298(5):C1087-99. doi: 10.1152/ajpcell.00388.2009. Epub 2010 Feb 24.


Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice.

Miniati D, Jelin EB, Ng J, Wu J, Carlson TR, Wu X, Looney MR, Wang RA.

Am J Physiol Lung Cell Mol Physiol. 2010 Feb;298(2):L169-77. doi: 10.1152/ajplung.00188.2009. Epub 2009 Nov 20.


[Relationship between the laccase production of Pleurotus ostreatus and the full wavelength scan for the fermentation liquid].

Cheng FS, Sheng JP, Wang RA, Shen L.

Guang Pu Xue Yu Guang Pu Fen Xi. 2009 Aug;29(8):2157-60. Chinese.


Arterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation.

Herbert SP, Huisken J, Kim TN, Feldman ME, Houseman BT, Wang RA, Shokat KM, Stainier DY.

Science. 2009 Oct 9;326(5950):294-8. doi: 10.1126/science.1178577.


Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease.

Murphy PA, Lu G, Shiah S, Bollen AW, Wang RA.

Lab Invest. 2009 Sep;89(9):971-82. doi: 10.1038/labinvest.2009.62. Epub 2009 Jun 22. Erratum in: Lab Invest. 2009 Sep;89(9):1071.


Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis.

Kim YH, Hu H, Guevara-Gallardo S, Lam MT, Fong SY, Wang RA.

Development. 2008 Nov;135(22):3755-64. doi: 10.1242/dev.022475.

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