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Items: 1 to 50 of 419


Targeted delivery of nitric oxide via a 'bump-and-hole'-based enzyme-prodrug pair.

Hou J, Pan Y, Zhu D, Fan Y, Feng G, Wei Y, Wang H, Qin K, Zhao T, Yang Q, Zhu Y, Che Y, Liu Y, Cheng J, Kong D, Wang PG, Shen J, Zhao Q.

Nat Chem Biol. 2019 Feb;15(2):151-160. doi: 10.1038/s41589-018-0190-5. Epub 2018 Dec 31.


N-acetyltransferases from three different organisms displaying distinct selectivity toward hexosamines and N-terminal amine of peptides.

Zhang P, Liu P, Xu Y, Liang Y, Wang PG, Cheng J.

Carbohydr Res. 2019 Jan 15;472:72-75. doi: 10.1016/j.carres.2018.11.011. Epub 2018 Nov 22.


Site-Specific N-Glycosylation on the AAV8 Capsid Protein.

Aloor A, Zhang J, Gashash EA, Parameswaran A, Chrzanowski M, Ma C, Diao Y, Wang PG, Xiao W.

Viruses. 2018 Nov 17;10(11). pii: E644. doi: 10.3390/v10110644.


Lower expression of Bax predicts poor clinical outcome in patients with glioma after curative resection and radiotherapy/chemotherapy.

Wang PG, Li YT, Pan Y, Gao ZZ, Guan XW, Jia L, Liu FT.

J Neurooncol. 2019 Jan;141(1):71-81. doi: 10.1007/s11060-018-03031-9. Epub 2018 Nov 16.


Direct Cloning of Bacterial Surface Polysaccharide Gene Cluster for One-Step Production of Glycoconjugate Vaccine.

Ma Z, Zhang H, Li L, Chen M, Wang PG.

ACS Infect Dis. 2018 Dec 18. doi: 10.1021/acsinfecdis.8b00187. [Epub ahead of print]


Zika Virus Infection in Hypothalamus Causes Hormone Deficiencies and Leads to Irreversible Growth Delay and Memory Impairment in Mice.

Wu YH, Cui XY, Yang W, Fan DY, Liu D, Wang PG, An J.

Cell Rep. 2018 Nov 6;25(6):1537-1547.e4. doi: 10.1016/j.celrep.2018.10.025.


[Analysis of serum epidemiological characteristics of hepatitis B among the population of 1-59 year-old in Gansu Province].

Wang PG, Zhang XS, An J, Tang Y, Zhang NJ, Wang XL, Wang XX, Liang XF, Zhang BL, Jiao YZ, Bao JY, Deng L, Li XB, Li H.

Zhonghua Yu Fang Yi Xue Za Zhi. 2018 Oct 6;52(10):1056-1058. doi: 10.3760/cma.j.issn.0253-9624.2018.10.017. Chinese. No abstract available.


Machine-Driven Enzymatic Oligosaccharide Synthesis by Using a Peptide Synthesizer.

Zhang J, Chen C, Gadi MR, Gibbons C, Guo Y, Cao X, Edmunds G, Wang S, Liu D, Yu J, Wen L, Wang PG.

Angew Chem Int Ed Engl. 2018 Dec 17;57(51):16638-16642. doi: 10.1002/anie.201810661. Epub 2018 Nov 26.


Isolation and characterization of an antioxidant exopolysaccharide produced by Bacillus sp. S-1 from Sichuan Pickles.

Hu X, Pang X, Wang PG, Chen M.

Carbohydr Polym. 2019 Jan 15;204:9-16. doi: 10.1016/j.carbpol.2018.09.069. Epub 2018 Sep 29.


Synthesis of Phenolic Glycosides: Glycosylation of Sugar Lactols with Aryl Bromides via Dual Photoredox/Ni Catalysis.

Ye H, Xiao C, Zhou QQ, Wang PG, Xiao WJ.

J Org Chem. 2018 Nov 2;83(21):13325-13334. doi: 10.1021/acs.joc.8b02129. Epub 2018 Oct 22.


Protected and De-protected Platinum(IV) Glycoconjugates With GLUT1 and OCT2-Mediated Selective Cancer Targeting: Demonstrated Enhanced Transporter-Mediated Cytotoxic Properties in vitro and in vivo.

Ma J, Liu H, Xi Z, Hou J, Li Y, Niu J, Liu T, Bi S, Wang X, Wang C, Wang J, Xie S, Wang PG.

Front Chem. 2018 Sep 21;6:386. doi: 10.3389/fchem.2018.00386. eCollection 2018.


Building and Breaking Bonds via a Compact S-Propargyl-Cysteine to Chemically Control Enzymes and Modify Proteins.

Liu J, Cheng R, Wu H, Li S, Wang PG, DeGrado WF, Rozovsky S, Wang L.

Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12702-12706. doi: 10.1002/anie.201806197. Epub 2018 Sep 5.


Toward Automated Enzymatic Synthesis of Oligosaccharides.

Wen L, Edmunds G, Gibbons C, Zhang J, Gadi MR, Zhu H, Fang J, Liu X, Kong Y, Wang PG.

Chem Rev. 2018 Sep 12;118(17):8151-8187. doi: 10.1021/acs.chemrev.8b00066. Epub 2018 Jul 16.


Mutation W222L at the Receptor Binding Site of Hemagglutinin Could Facilitate Viral Adaption from Equine Influenza A(H3N8) Virus to Dogs.

Wen F, Blackmon S, Olivier AK, Li L, Guan M, Sun H, Wang PG, Wan XF.

J Virol. 2018 Aug 29;92(18). pii: e01115-18. doi: 10.1128/JVI.01115-18. Print 2018 Sep 15.


Facile and Stereo-Selective Synthesis of UDP-α-D-xylose and UDP-β-L-arabinose Using UDP-Sugar Pyrophosphorylase.

Wang J, Greenway H, Li S, Wei M, Polizzi SJ, Wang PG.

Front Chem. 2018 May 23;6:163. doi: 10.3389/fchem.2018.00163. eCollection 2018.


Biomarker-Based Metabolic Labeling for Redirected and Enhanced Immune Response.

Li S, Yu B, Wang J, Zheng Y, Zhang H, Walker MJ, Yuan Z, Zhu H, Zhang J, Wang PG, Wang B.

ACS Chem Biol. 2018 Jun 15;13(6):1686-1694. doi: 10.1021/acschembio.8b00350. Epub 2018 Jun 1.


Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens.

Yu H, Santra A, Li Y, McArthur JB, Ghosh T, Yang X, Wang PG, Chen X.

Org Biomol Chem. 2018 Jun 6;16(22):4076-4080. doi: 10.1039/c8ob01087k.


A case of acrokeratoelastoidosis.

Xu CC, Fu LY, Lin D, Li H, Du WH, Wang PG.

Clin Exp Dermatol. 2018 Oct;43(7):819-820. doi: 10.1111/ced.13603. Epub 2018 May 14. No abstract available.


High level expression and glycosylation of recombinant Mycobacterium tuberculosis Ala-Pro-rich antigen in Pichia pastoris.

Wang S, Wang Y, Wang PG, Chen M, Kong Y.

Protein Expr Purif. 2018 Oct;150:67-71. doi: 10.1016/j.pep.2018.05.004. Epub 2018 May 9.


Novel mutations in Chinese Han patients with tuberous sclerosis complex: Case series and review of the published work.

Zheng LY, Lee YW, Han Y, Tang LL, Cheng YY, Dou JF, Zhou FS, Zheng XD, Wang HY, Wang PG, Gao M.

J Dermatol. 2018 Jul;45(7):867-870. doi: 10.1111/1346-8138.14349. Epub 2018 May 9. Review.


Facile Chemoenzymatic Synthesis of O-Mannosyl Glycans.

Wang S, Zhang Q, Chen C, Guo Y, Gadi MR, Yu J, Westerlind U, Liu Y, Cao X, Wang PG, Li L.

Angew Chem Int Ed Engl. 2018 Jul 20;57(30):9268-9273. doi: 10.1002/anie.201803536. Epub 2018 May 18.


A One-Step Chemoenzymatic Labeling Strategy for Probing Sialylated Thomsen-Friedenreich Antigen.

Wen L, Liu D, Zheng Y, Huang K, Cao X, Song J, Wang PG.

ACS Cent Sci. 2018 Apr 25;4(4):451-457. doi: 10.1021/acscentsci.7b00573. Epub 2018 Feb 23.


Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia.

Li J, Li S, Guo J, Li Q, Long J, Ma C, Ding Y, Yan C, Li L, Wu Z, Zhu H, Li KK, Wen L, Zhang Q, Xue Q, Zhao C, Liu N, Ivanov I, Luo M, Xi R, Long H, Wang PG, Chen Y.

J Med Chem. 2018 May 10;61(9):4155-4164. doi: 10.1021/acs.jmedchem.8b00241. Epub 2018 Apr 29.


N-Glycosyltransferase from Aggregatibacter aphrophilus synthesizes glycopeptides with relaxed nucleotide-activated sugar donor selectivity.

Kong Y, Li J, Hu X, Wang Y, Meng Q, Gu G, Wang PG, Chen M.

Carbohydr Res. 2018 Jun 15;462:7-12. doi: 10.1016/j.carres.2018.03.008. Epub 2018 Mar 19.


Genetically Encoding Fluorosulfate-l-tyrosine To React with Lysine, Histidine, and Tyrosine via SuFEx in Proteins in Vivo.

Wang N, Yang B, Fu C, Zhu H, Zheng F, Kobayashi T, Liu J, Li S, Ma C, Wang PG, Wang Q, Wang L.

J Am Chem Soc. 2018 Apr 18;140(15):4995-4999. doi: 10.1021/jacs.8b01087. Epub 2018 Apr 5.


Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer's disease.

Zhang Q, Ma C, Gearing M, Wang PG, Chin LS, Li L.

Acta Neuropathol Commun. 2018 Mar 1;6(1):19. doi: 10.1186/s40478-018-0524-2.


Peptide adjacent to glycosylation sites impacts immunogenicity of glycoconjugate vaccine.

Ma Z, Zhang H, Wang PG, Liu XW, Chen M.

Oncotarget. 2017 Jun 30;9(1):75-82. doi: 10.18632/oncotarget.19944. eCollection 2018 Jan 2.


Post-Exercise Carbohydrate-Energy Replacement Attenuates Insulin Sensitivity and Glucose Tolerance the Following Morning in Healthy Adults.

Taylor HL, Wu CL, Chen YC, Wang PG, Gonzalez JT, Betts JA.

Nutrients. 2018 Jan 25;10(2). pii: E123. doi: 10.3390/nu10020123.


Synthetic and immunological studies on trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.

Li M, Yu F, Yao C, Wang PG, Liu Y, Zhao W.

Org Biomol Chem. 2018 Feb 7;16(6):993-999. doi: 10.1039/c7ob02976d.


Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins.

Purohit S, Li T, Guan W, Song X, Song J, Tian Y, Li L, Sharma A, Dun B, Mysona D, Ghamande S, Rungruang B, Cummings RD, Wang PG, She JX.

Nat Commun. 2018 Jan 17;9(1):258. doi: 10.1038/s41467-017-02747-y.


Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions.

Yang B, Tang S, Ma C, Li ST, Shao GC, Dang B, DeGrado WF, Dong MQ, Wang PG, Ding S, Wang L.

Nat Commun. 2017 Dec 21;8(1):2240. doi: 10.1038/s41467-017-02409-z.


Association of HLA-DQB1*03:03 with pityriasis rosea in Chinese patients.

Fu LY, Xu CC, Zheng XD, Chen G, Zhu J, Wang PG.

Clin Exp Dermatol. 2018 Jun;43(4):389-392. doi: 10.1111/ced.13313. Epub 2017 Dec 8.


Matrix effects and application of matrix effect factor.

Zhou W, Yang S, Wang PG.

Bioanalysis. 2017 Dec;9(23):1839-1844. doi: 10.4155/bio-2017-0214. Epub 2017 Nov 24. No abstract available.


A Y161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 Influenza A Virus in Cells.

Wen F, Li L, Zhao N, Chiang MJ, Xie H, Cooley J, Webby R, Wang PG, Wan XF.

J Virol. 2018 Jan 2;92(2). pii: e01621-17. doi: 10.1128/JVI.01621-17. Print 2018 Jan 15.


Sequential one-pot multienzyme synthesis of hyaluronan and its derivative.

Li S, Wang S, Fu X, Liu XW, Wang PG, Fang J.

Carbohydr Polym. 2017 Dec 15;178:221-227. doi: 10.1016/j.carbpol.2017.09.041. Epub 2017 Sep 14.


A Chemoenzymatic Histology Method for O-GlcNAc Detection.

Aguilar AL, Hou X, Wen L, Wang PG, Wu P.

Chembiochem. 2017 Dec 14;18(24):2416-2421. doi: 10.1002/cbic.201700515. Epub 2017 Dec 5.


Decoding glycan protein interactions by a new class of asymmetric N-glycans.

Wu Z, Liu Y, Li L, Wan XF, Zhu H, Guo Y, Wei M, Guan W, Wang PG.

Org Biomol Chem. 2017 Oct 31;15(42):8946-8951. doi: 10.1039/c7ob02303k.


Structure based design, synthesis and activity studies of small hybrid molecules as HDAC and G9a dual inhibitors.

Zang L, Kondengaden SM, Zhang Q, Li X, Sigalapalli DK, Kondengadan SM, Huang K, Li KK, Li S, Xiao Z, Wen L, Zhu H, Babu BN, Wang L, Che F, Wang PG.

Oncotarget. 2017 Jun 28;8(38):63187-63207. doi: 10.18632/oncotarget.18730. eCollection 2017 Sep 8.


[Application value on localization and evaluation of sentinel lymph nodes in early-stage breast cancer with CT lymphography].

Wang PG, Tan HN, Wang B, Xiao HJ, Gao JB.

Zhonghua Yi Xue Za Zhi. 2017 Sep 19;97(35):2762-2765. doi: 10.3760/cma.j.issn.0376-2491.2017.35.011. Chinese.


H. pylori α1-3/4-fucosyltransferase (Hp3/4FT)-catalyzed one-pot multienzyme (OPME) synthesis of Lewis antigens and human milk fucosides.

Yu H, Li Y, Wu Z, Li L, Zeng J, Zhao C, Wu Y, Tasnima N, Wang J, Liu H, Gadi MR, Guan W, Wang PG, Chen X.

Chem Commun (Camb). 2017 Oct 5;53(80):11012-11015. doi: 10.1039/c7cc05403c.


An enzymatic strategy to asymmetrically branched N-glycans.

Calderon AD, Zhou J, Guan W, Wu Z, Guo Y, Bai J, Li Q, Wang PG, Fang J, Li L.

Org Biomol Chem. 2017 Sep 13;15(35):7258-7262. doi: 10.1039/c7ob01765k.


A General Chemoenzymatic Strategy for the Synthesis of Glycosphingolipids.

Liu Y, Wen L, Li L, Gadi MR, Guan W, Huang K, Xiao Z, Wei M, Ma C, Zhang Q, Yu H, Chen X, Wang PG, Fang J.

European J Org Chem. 2016 Sep;2016(25):4315-4320. doi: 10.1002/ejoc.201600950. Epub 2016 Aug 16.


Potentiating the immune response of MUC1-based antitumor vaccines using a peptide-based nanovector as a promising vaccine adjuvant.

Liu Y, Wang Y, Yu F, Zhang Z, Yang Z, Zhang W, Wang PG, Zhao W.

Chem Commun (Camb). 2017 Aug 22;53(68):9486-9489. doi: 10.1039/c7cc04386d.


Axl is not an indispensable factor for Zika virus infection in mice.

Wang ZY, Wang Z, Zhen ZD, Feng KH, Guo J, Gao N, Fan DY, Han DS, Wang PG, An J.

J Gen Virol. 2017 Aug;98(8):2061-2068. doi: 10.1099/jgv.0.000886. Epub 2017 Aug 8.


A novel enzymatic method for synthesis of glycopeptides carrying natural eukaryotic N-glycans.

Xu Y, Wu Z, Zhang P, Zhu H, Zhu H, Song Q, Wang L, Wang F, Wang PG, Cheng J.

Chem Commun (Camb). 2017 Aug 10;53(65):9075-9077. doi: 10.1039/c7cc04362g.


An Insight into Glyco-Microheterogeneity of Plasma von Willebrand Factor by Mass Spectrometry.

Gashash EA, Aloor A, Li D, Zhu H, Xu XQ, Xiao C, Zhang J, Parameswaran A, Song J, Ma C, Xiao W, Wang PG.

J Proteome Res. 2017 Sep 1;16(9):3348-3362. doi: 10.1021/acs.jproteome.7b00359. Epub 2017 Jul 27.


Highly efficient chemoenzymatic synthesis and facile purification of α-Gal pentasaccharyl ceramide Galα3nLc4βCer.

Santra A, Li Y, Yu H, Slack TJ, Wang PG, Chen X.

Chem Commun (Camb). 2017 Jul 20;53(59):8280-8283. doi: 10.1039/c7cc04090c.


Sialic acid linkage-specific permethylation for improved profiling of protein glycosylation by MALDI-TOF MS.

Jiang K, Zhu H, Li L, Guo Y, Gashash E, Ma C, Sun X, Li J, Zhang L, Wang PG.

Anal Chim Acta. 2017 Aug 15;981:53-61. doi: 10.1016/j.aca.2017.05.029. Epub 2017 Jun 13.


Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis.

Sheng ZY, Gao N, Wang ZY, Cui XY, Zhou DS, Fan DY, Chen H, Wang PG, An J.

Front Cell Infect Microbiol. 2017 Jun 21;7:272. doi: 10.3389/fcimb.2017.00272. eCollection 2017.

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