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Oestrogen-deficiency induces bone loss by modulating CD14+ monocyte and CD4+ T cell DR3 expression and serum TL1A levels.

Collins FL, Stone MD, Turton J, McCabe LR, Wang ECY, Williams AS.

BMC Musculoskelet Disord. 2019 Jul 12;20(1):326. doi: 10.1186/s12891-019-2704-z.


A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth.

Wang ECE, Dai Z, Ferrante AW, Drake CG, Christiano AM.

Cell Stem Cell. 2019 Apr 4;24(4):654-669.e6. doi: 10.1016/j.stem.2019.01.011. Epub 2019 Mar 28.


Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell-mediated control of HIV-1, HCV, and HTLV-1.

Boelen L, Debebe B, Silveira M, Salam A, Makinde J, Roberts CH, Wang ECY, Frater J, Gilmour J, Twigger K, Ladell K, Miners KL, Jayaraman J, Traherne JA, Price DA, Qi Y, Martin MP, Macallan DC, Thio CL, Astemborski J, Kirk G, Donfield SM, Buchbinder S, Khakoo SI, Goedert JJ, Trowsdale J, Carrington M, Kollnberger S, Asquith B.

Sci Immunol. 2018 Nov 9;3(29). pii: eaao2892. doi: 10.1126/sciimmunol.aao2892.


HCMV-Encoded NK Modulators: Lessons From in vitro and in vivo Genetic Variation.

Patel M, Vlahava VM, Forbes SK, Fielding CA, Stanton RJ, Wang ECY.

Front Immunol. 2018 Oct 1;9:2214. doi: 10.3389/fimmu.2018.02214. eCollection 2018. Review.


High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms.

Nightingale K, Lin KM, Ravenhill BJ, Davies C, Nobre L, Fielding CA, Ruckova E, Fletcher-Etherington A, Soday L, Nichols H, Sugrue D, Wang ECY, Moreno P, Umrania Y, Huttlin EL, Antrobus R, Davison AJ, Wilkinson GWG, Stanton RJ, Tomasec P, Weekes MP.

Cell Host Microbe. 2018 Sep 12;24(3):447-460.e11. doi: 10.1016/j.chom.2018.07.011. Epub 2018 Aug 16.


Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses.

Wang ECY, Pjechova M, Nightingale K, Vlahava VM, Patel M, Ruckova E, Forbes SK, Nobre L, Antrobus R, Roberts D, Fielding CA, Seirafian S, Davies J, Murrell I, Lau B, Wilkie GS, Suárez NM, Stanton RJ, Vojtesek B, Davison A, Lehner PJ, Weekes MP, Wilkinson GWG, Tomasec P.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):4998-5003. doi: 10.1073/pnas.1720950115. Epub 2018 Apr 24.


RORα-expressing T regulatory cells restrain allergic skin inflammation.

Malhotra N, Leyva-Castillo JM, Jadhav U, Barreiro O, Kam C, O'Neill NK, Meylan F, Chambon P, von Andrian UH, Siegel RM, Wang EC, Shivdasani R, Geha RS.

Sci Immunol. 2018 Mar 2;3(21). pii: eaao6923. doi: 10.1126/sciimmunol.aao6923.


Novel therapies for alopecia areata: The era of rational drug development.

Wang ECE, Dai Z, Christiano AM.

J Allergy Clin Immunol. 2018 Feb;141(2):499-504. doi: 10.1016/j.jaci.2017.10.028. Epub 2017 Dec 28. Review.


Death Receptor 3 regulates distinct pathological attributes of acute versus chronic murine allergic lung inflammation.

Singh RK, Perks WV, Twohig JP, Kidd EJ, Broadley K, Farrow SN, Williams AS, Taylor PR, Wang ECY.

Cell Immunol. 2017 Oct;320:62-70. doi: 10.1016/j.cellimm.2017.09.005. Epub 2017 Sep 15.


The Changing Landscape of Alopecia Areata: The Translational Landscape.

Wang ECE, Christiano AM.

Adv Ther. 2017 Jul;34(7):1586-1593. doi: 10.1007/s12325-017-0540-9. Epub 2017 Jun 23. Review.


Leptomeningeal failure in patients with breast cancer receiving stereotactic radiosurgery for brain metastases.

Wang EC, Huang AJ, Huang KE, McTyre ER, Lo HW, Watabe K, Metheny-Barlow L, Laxton AW, Tatter SB, Strowd RE, Chan MD, Page BR.

J Clin Neurosci. 2017 Sep;43:6-10. doi: 10.1016/j.jocn.2017.04.033. Epub 2017 May 13.


Gamma Knife radiosurgery for brain metastases from gastrointestinal primary.

Page BR, Wang EC, White L, McTyre E, Peiffer A, Alistar A, Mu F, Loganathan A, Bourland JD, Laxton AW, Tatter SB, Chan MD.

J Med Imaging Radiat Oncol. 2017 Aug;61(4):522-527. doi: 10.1111/1754-9485.12584. Epub 2017 Jan 31.


CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss.

Collins FL, Williams JO, Bloom AC, Singh RK, Jordan L, Stone MD, McCabe LR, Wang ECY, Williams AS.

Bone. 2017 Apr;97:94-104. doi: 10.1016/j.bone.2017.01.002. Epub 2017 Jan 4.


Death Receptor 3 Promotes Chemokine-Directed Leukocyte Recruitment in Acute Resolving Inflammation and Is Essential for Pathological Development of Mesothelial Fibrosis in Chronic Disease.

Perks WV, Singh RK, Jones GW, Twohig JP, Williams AS, Humphreys IR, Taylor PR, Jones SA, Wang ECY.

Am J Pathol. 2016 Nov;186(11):2813-2823. doi: 10.1016/j.ajpath.2016.07.021. Epub 2016 Sep 21.


Review: Novel Insights Into Tumor Necrosis Factor Receptor, Death Receptor 3, and Progranulin Pathways in Arthritis and Bone Remodeling.

Williams A, Wang EC, Thurner L, Liu CJ.

Arthritis Rheumatol. 2016 Dec;68(12):2845-2856. doi: 10.1002/art.39816. Review. No abstract available.


Characterization of death receptor 3-dependent aortic changes during inflammatory arthritis.

Williams JO, Wang EC, Lang D, Williams AS.

Pharmacol Res Perspect. 2016 Jun 10;4(4):e00240. eCollection 2016 Aug.


A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection.

Jia LG, Bamias G, Arseneau KO, Burkly LC, Wang EC, Gruszka D, Pizarro TT, Cominelli F.

J Immunol. 2016 Jul 1;197(1):377-86. doi: 10.4049/jimmunol.1502466. Epub 2016 May 27.


Death Receptor 3 (TNFRSF25) Increases Mineral Apposition by Osteoblasts and Region Specific New Bone Formation in the Axial Skeleton of Male DBA/1 Mice.

Collins FL, Williams JO, Bloom AC, Stone MD, Choy E, Wang EC, Williams AS.

J Immunol Res. 2015;2015:901679. doi: 10.1155/2015/901679. Epub 2015 May 3.


Human cytomegalovirus: taking the strain.

Wilkinson GW, Davison AJ, Tomasec P, Fielding CA, Aicheler R, Murrell I, Seirafian S, Wang EC, Weekes M, Lehner PJ, Wilkie GS, Stanton RJ.

Med Microbiol Immunol. 2015 Jun;204(3):273-84. doi: 10.1007/s00430-015-0411-4. Epub 2015 Apr 17. Review.


Nanoparticle formulations of histone deacetylase inhibitors for effective chemoradiotherapy in solid tumors.

Wang EC, Min Y, Palm RC, Fiordalisi JJ, Wagner KT, Hyder N, Cox AD, Caster JM, Tian X, Wang AZ.

Biomaterials. 2015 May;51:208-215. doi: 10.1016/j.biomaterials.2015.02.015. Epub 2015 Feb 19.


[Differential expression of microRNA in chronic hepatitis B patients of pi-wei dampness-heat syndrome and of gan depression Pi deficiency syndrome: a primary research].

Wang EC, Zhang L, Liu HW, Guo YL, Zhang F, He CW, Shen MM, Feng QS.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Nov;34(11):1324-8. Chinese.


Improvement in vision-related function with intravitreal aflibercept: data from phase 3 studies in wet age-related macular degeneration.

Yuzawa M, Fujita K, Wittrup-Jensen KU, Norenberg C, Zeitz O, Adachi K, Wang EC, Heier J, Kaiser P, Chong V, Korobelnik JF.

Ophthalmology. 2015 Mar;122(3):571-8. doi: 10.1016/j.ophtha.2014.09.024. Epub 2014 Nov 6.


HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells.

Stanton RJ, Prod'homme V, Purbhoo MA, Moore M, Aicheler RJ, Heinzmann M, Bailer SM, Haas J, Antrobus R, Weekes MP, Lehner PJ, Vojtesek B, Miners KL, Man S, Wilkie GS, Davison AJ, Wang ECY, Tomasec P, Wilkinson GWG.

Cell Host Microbe. 2014 Aug 13;16(2):201-214. doi: 10.1016/j.chom.2014.07.005.


Regulation of early cartilage destruction in inflammatory arthritis by death receptor 3.

Wang EC, Newton Z, Hayward OA, Clark SR, Collins F, Perks WV, Singh RK, Twohig JP, Williams AS.

Arthritis Rheumatol. 2014 Oct;66(10):2762-72. doi: 10.1002/art.38770.


Azide-alkyne cycloaddition for universal post-synthetic modifications of nucleic acids and effective synthesis of bioactive nucleic acid conjugates.

Su YC, Lo YL, Hwang CC, Wang LF, Wu MH, Wang EC, Wang YM, Wang TP.

Org Biomol Chem. 2014 Sep 14;12(34):6624-33. doi: 10.1039/c4ob01132e.


Quantitative temporal viromics: an approach to investigate host-pathogen interaction.

Weekes MP, Tomasec P, Huttlin EL, Fielding CA, Nusinow D, Stanton RJ, Wang EC, Aicheler R, Murrell I, Wilkinson GW, Lehner PJ, Gygi SP.

Cell. 2014 Jun 5;157(6):1460-72. doi: 10.1016/j.cell.2014.04.028.


Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation.

Fielding CA, Aicheler R, Stanton RJ, Wang EC, Han S, Seirafian S, Davies J, McSharry BP, Weekes MP, Antrobus PR, Prod'homme V, Blanchet FP, Sugrue D, Cuff S, Roberts D, Davison AJ, Lehner PJ, Wilkinson GW, Tomasec P.

PLoS Pathog. 2014 May 1;10(5):e1004058. doi: 10.1371/journal.ppat.1004058. eCollection 2014 May.


[Cluster analysis on TCM syndrome characteristics of chronic hepatitis B].

Wang EC, Tang L, Wang J, Zhang L, Cao CH, Feng QS.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Jan;34(1):39-42. Chinese.


Effect of drug release kinetics on nanoparticle therapeutic efficacy and toxicity.

Sethi M, Sukumar R, Karve S, Werner ME, Wang EC, Moore DT, Kowalczyk SR, Zhang L, Wang AZ.

Nanoscale. 2014 Feb 21;6(4):2321-2327. doi: 10.1039/c3nr05961h. Epub 2014 Jan 14.


Burden of menstrual symptoms in Japanese women - an analysis of medical care-seeking behavior from a survey-based study.

Tanaka E, Momoeda M, Osuga Y, Rossi B, Nomoto K, Hayakawa M, Kokubo K, Wang EC.

Int J Womens Health. 2013 Dec 17;6:11-23. doi: 10.2147/IJWH.S52429. eCollection 2013.


Effective and site-specific phosphoramidation reaction for universally labeling nucleic acids.

Su YC, Chen HY, Ko NC, Hwang CC, Wu MH, Wang LF, Wang YM, Chang SN, Wang EC, Wang TP.

Anal Biochem. 2014 Mar 15;449:118-28. doi: 10.1016/j.ab.2013.12.021. Epub 2013 Dec 19.


Nanoparticles and their applications in cell and molecular biology.

Wang EC, Wang AZ.

Integr Biol (Camb). 2014 Jan;6(1):9-26. doi: 10.1039/c3ib40165k. Review.


Burden of menstrual symptoms in Japanese women: results from a survey-based study.

Tanaka E, Momoeda M, Osuga Y, Rossi B, Nomoto K, Hayakawa M, Kokubo K, Wang EC.

J Med Econ. 2013 Nov;16(11):1255-66. doi: 10.3111/13696998.2013.830974. Epub 2013 Sep 10.


Differential cell responses to nanoparticle docetaxel and small molecule docetaxel at a sub-therapeutic dose range.

Wang EC, Sinnott R, Werner ME, Sethi M, Whitehurst AW, Wang AZ.

Nanomedicine. 2014 Feb;10(2):321-8. doi: 10.1016/j.nano.2013.07.012. Epub 2013 Aug 3.


A real-time impedance-sensing chip for the detection of emulsion phase separation.

Lin YS, Chou WL, Yang CH, Huang KS, Wang EC, Chen CY, Lin YH, Huang HM.

Electrophoresis. 2013 Jun;34(12):1743-8. doi: 10.1002/elps.201200517.


Single Treatment with 100-Microsecond Alexandrite Laser Clears Selected Acquired Melanocytic Nevi in Type IV Asian Facial Skin.

Wang EC, Sen P, Goh CL, Chua SH.

J Cutan Aesthet Surg. 2013 Jan;6(1):21-6. doi: 10.4103/0974-2077.110092.


Burden of comorbidities among Japanese patients with atrial fibrillation: a case study of dyspepsia.

Kinoshita Y, Dibonaventura M, Rossi B, Iwamoto K, Wang EC, Briere JB.

Clin Exp Gastroenterol. 2013 May 20;6:51-9. doi: 10.2147/CEG.S39628. Print 2013. Erratum in: Clin Exp Gastroenterol. 2013 Sep 23;6:193.


Preclinical evaluation of Genexol-PM, a nanoparticle formulation of paclitaxel, as a novel radiosensitizer for the treatment of non-small cell lung cancer.

Werner ME, Cummings ND, Sethi M, Wang EC, Sukumar R, Moore DT, Wang AZ.

Int J Radiat Oncol Biol Phys. 2013 Jul 1;86(3):463-468. doi: 10.1016/j.ijrobp.2013.02.009.


The paradox of NKp46+ natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon α treatment.

Pembroke T, Christian A, Jones E, Hills RK, Wang EC, Gallimore AM, Godkin A.

Gut. 2014 Mar;63(3):515-24. doi: 10.1136/gutjnl-2013-304472. Epub 2013 May 11.


Obstacles and solutions to screening psoriasis patients for cardiovascular risk factors.

Wang EC, Ker KJ, Chuah SY, Pan JY.

J Eur Acad Dermatol Venereol. 2014 Jun;28(6):819-23. doi: 10.1111/jdv.12159. Epub 2013 Apr 26.


Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses.

Smith W, Tomasec P, Aicheler R, Loewendorf A, Nemčovičová I, Wang EC, Stanton RJ, Macauley M, Norris P, Willen L, Ruckova E, Nomoto A, Schneider P, Hahn G, Zajonc DM, Ware CF, Wilkinson GW, Benedict CA.

Cell Host Microbe. 2013 Mar 13;13(3):324-35. doi: 10.1016/j.chom.2013.02.003.


Is Illinois heeding the call to regionalize pancreatic surgery?

Hayman AV, Fisher MJ, Kluz T, Merkow RP, Wang EC, Bentrem DJ.

J Surg Oncol. 2013 Jun;107(7):685-91. doi: 10.1002/jso.23310. Epub 2013 Jan 17.


Advanced aqueous-phase phosphoramidation reactions for effectively synthesizing peptide-oligonucleotide conjugates trafficked into a human cell line.

Wang TP, Ko NC, Su YC, Wang EC, Severance S, Hwang CC, Shih YT, Wu MH, Chen YH.

Bioconjug Chem. 2012 Dec 19;23(12):2417-33. doi: 10.1021/bc300444y. Epub 2012 Nov 30.


Extramammary Paget disease: Immunohistochemistry is critical to distinguish potential mimickers.

Wang EC, Kwah YC, Tan WP, Lee JS, Tan SH.

Dermatol Online J. 2012 Sep 15;18(9):4.


Differential effect of nutritional status on vascular surgery outcomes in a Veterans Affairs versus private hospital setting.

Boitano LT, Wang EC, Kibbe MR.

Am J Surg. 2012 Nov;204(5):e27-37. doi: 10.1016/j.amjsurg.2012.07.023. Epub 2012 Sep 25.


Pd(II)-mediated cyclization of o-allylbenzaldehydes in water: a novel synthesis of isocoumarins.

Chen PY, Huang KS, Tsai CC, Wang TP, Wang EC.

Org Lett. 2012 Sep 21;14(18):4930-3. Epub 2012 Aug 30.


Atrial fibrillation ablation in patients undergoing aortic valve replacement.

Malaisrie SC, Lee R, Kruse J, Lapin B, Wang EC, Bonow RO, McCarthy PM.

J Heart Valve Dis. 2012 May;21(3):350-7.


Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+ T-cell immunity.

Pembroke T, Rees I, Gallagher K, Jones E, Mizen P, Navruzov T, Freedman A, Fielding C, Humphreys IR, Wang EC, Gallimore AM, Godkin A.

Eur J Immunol. 2012 Sep;42(9):2383-94. doi: 10.1002/eji.201142072. Epub 2012 Aug 6.


On death receptor 3 and its ligands….

Wang EC.

Immunology. 2012 Sep;137(1):114-6. doi: 10.1111/j.1365-2567.2012.03606.x. No abstract available.

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