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Items: 1 to 50 of 122

1.

Editorial: Neuroprotection in Brain Hypoxia.

Otero-Losada M, Wandosell FG, Garcia-Segura LM, Capani F.

Front Neurosci. 2019 Mar 22;13:212. doi: 10.3389/fnins.2019.00212. eCollection 2019. No abstract available.

2.

Botulinum Neurotoxin Light Chains Expressed by Defective Herpes Simplex Virus Type-1 Vectors Cleave SNARE Proteins and Inhibit CGRP Release in Rat Sensory Neurons.

Joussain C, Le Coz O, Pichugin A, Marconi P, Lim F, Sicurella M, Salonia A, Montorsi F, Wandosell F, Foster K, Giuliano F, Epstein AL, Aranda Muñoz A.

Toxins (Basel). 2019 Feb 19;11(2). pii: E123. doi: 10.3390/toxins11020123.

3.

WIP-YAP/TAZ as A New Pro-Oncogenic Pathway in Glioma.

Rivas S, Antón IM, Wandosell F.

Cancers (Basel). 2018 Jun 9;10(6). pii: E191. doi: 10.3390/cancers10060191.

4.

Ovarian Function Modulates the Effects of Long-Chain Polyunsaturated Fatty Acids on the Mouse Cerebral Cortex.

Herrera JL, Ordoñez-Gutierrez L, Fabrias G, Casas J, Morales A, Hernandez G, Acosta NG, Rodriguez C, Prieto-Valiente L, Garcia-Segura LM, Alonso R, Wandosell FG.

Front Cell Neurosci. 2018 Apr 24;12:103. doi: 10.3389/fncel.2018.00103. eCollection 2018.

5.

R-Ras1 and R-Ras2 Are Essential for Oligodendrocyte Differentiation and Survival for Correct Myelination in the Central Nervous System.

Sanz-Rodriguez M, Gruart A, Escudero-Ramirez J, de Castro F, Delgado-García JM, Wandosell F, Cubelos B.

J Neurosci. 2018 May 30;38(22):5096-5110. doi: 10.1523/JNEUROSCI.3364-17.2018. Epub 2018 May 2.

6.

Sex steroid hormones as neuroprotective elements in ischemia models.

Céspedes Rubio ÁE, Pérez-Alvarez MJ, Lapuente Chala C, Wandosell F.

J Endocrinol. 2018 May;237(2):R65-R81. doi: 10.1530/JOE-18-0129. Review.

PMID:
29654072
7.

Role of Akt Isoforms Controlling Cancer Stem Cell Survival, Phenotype and Self-Renewal.

Rivas S, Gómez-Oro C, Antón IM, Wandosell F.

Biomedicines. 2018 Mar 7;6(1). pii: E29. doi: 10.3390/biomedicines6010029. Review.

8.

Role of mTORC1 Controlling Proteostasis after Brain Ischemia.

Perez-Alvarez MJ, Villa Gonzalez M, Benito-Cuesta I, Wandosell FG.

Front Neurosci. 2018 Feb 15;12:60. doi: 10.3389/fnins.2018.00060. eCollection 2018. Review.

9.

Dihydroceramide Desaturase 1 Inhibitors Reduce Amyloid-β Levels in Primary Neurons from an Alzheimer's Disease Transgenic Model.

Ordóñez-Gutiérrez L, Benito-Cuesta I, Abad JL, Casas J, Fábrias G, Wandosell F.

Pharm Res. 2018 Feb 6;35(3):49. doi: 10.1007/s11095-017-2312-2.

PMID:
29411122
10.

Antibody-functionalized polymer nanoparticle leading to memory recovery in Alzheimer's disease-like transgenic mouse model.

Carradori D, Balducci C, Re F, Brambilla D, Le Droumaguet B, Flores O, Gaudin A, Mura S, Forloni G, Ordoñez-Gutierrez L, Wandosell F, Masserini M, Couvreur P, Nicolas J, Andrieux K.

Nanomedicine. 2018 Feb;14(2):609-618. doi: 10.1016/j.nano.2017.12.006. Epub 2017 Dec 15.

PMID:
29248676
11.

Crosstalk between WIP and Rho family GTPases.

Antón IM, Gómez-Oro C, Rivas S, Wandosell F.

Small GTPases. 2018 Jan 29:1-7. doi: 10.1080/21541248.2017.1390522. [Epub ahead of print]

PMID:
29172947
12.

Assessment of Autophagy in Neurons and Brain Tissue.

Benito-Cuesta I, Diez H, Ordoñez L, Wandosell F.

Cells. 2017 Aug 23;6(3). pii: E25. doi: 10.3390/cells6030025. Review.

13.

Mutant p53 oncogenic functions in cancer stem cells are regulated by WIP through YAP/TAZ.

Escoll M, Gargini R, Cuadrado A, Anton IM, Wandosell F.

Oncogene. 2017 Jun 22;36(25):3515-3527. doi: 10.1038/onc.2016.518. Epub 2017 Feb 6.

PMID:
28166194
14.

WIP Drives Tumor Progression through YAP/TAZ-Dependent Autonomous Cell Growth.

Gargini R, Escoll M, García E, García-Escudero R, Wandosell F, Antón IM.

Cell Rep. 2016 Nov 15;17(8):1962-1977. doi: 10.1016/j.celrep.2016.10.064.

15.

ImmunoPEGliposome-mediated reduction of blood and brain amyloid levels in a mouse model of Alzheimer's disease is restricted to aged animals.

Ordóñez-Gutiérrez L, Posado-Fernández A, Ahmadvand D, Lettiero B, Wu L, Antón M, Flores O, Moghimi SM, Wandosell F.

Biomaterials. 2017 Jan;112:141-152. doi: 10.1016/j.biomaterials.2016.07.027. Epub 2016 Aug 2.

PMID:
27760398
16.

Secreted herpes simplex virus-2 glycoprotein G alters thermal pain sensitivity by modifying NGF effects on TRPV1.

Cabrera JR, Viejo-Borbolla A, Alcamí A, Wandosell F.

J Neuroinflammation. 2016 Aug 30;13(1):210. doi: 10.1186/s12974-016-0677-5.

17.

AβPP/PS1 Transgenic Mice Show Sex Differences in the Cerebellum Associated with Aging.

Ordoñez-Gutierrez L, Fernandez-Perez I, Herrera JL, Anton M, Benito-Cuesta I, Wandosell F.

J Alzheimers Dis. 2016 Sep 6;54(2):645-56. doi: 10.3233/JAD-160572.

PMID:
27567877
18.

Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation.

Diez H, Benitez MJ, Fernandez S, Torres-Aleman I, Garrido JJ, Wandosell F.

Biochim Biophys Acta. 2016 Nov;1863(11):2574-2583. doi: 10.1016/j.bbamcr.2016.07.002. Epub 2016 Jul 12.

19.

Reticulon-4B/Nogo-B acts as a molecular linker between microtubules and actin cytoskeleton in vascular smooth muscle cells.

Rodríguez-Feo JA, Gallego-Delgado J, Puerto M, Wandosell F, Osende J.

Biochim Biophys Acta. 2016 Aug;1863(8):1985-95. doi: 10.1016/j.bbamcr.2016.04.025. Epub 2016 Apr 28. No abstract available.

20.

Angiotensin II type-2 receptor stimulation induces neuronal VEGF synthesis after cerebral ischemia.

Mateos L, Perez-Alvarez MJ, Wandosell F.

Biochim Biophys Acta. 2016 Jul;1862(7):1297-308. doi: 10.1016/j.bbadis.2016.03.013. Epub 2016 Apr 1.

21.

Oncogene-mediated tumor transformation sensitizes cells to autophagy induction.

Gargini R, García-Escudero V, Izquierdo M, Wandosell F.

Oncol Rep. 2016 Jun;35(6):3689-95. doi: 10.3892/or.2016.4699. Epub 2016 Mar 23.

PMID:
27035659
22.

Stroke and Neuroinflamation: Role of Sexual Hormones.

Perez-Alvarez MJ, Wandosell F.

Curr Pharm Des. 2016;22(10):1334-49. Review.

PMID:
26972291
23.

PTEN recruitment controls synaptic and cognitive function in Alzheimer's models.

Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA.

Nat Neurosci. 2016 Mar;19(3):443-53. doi: 10.1038/nn.4225. Epub 2016 Jan 18.

PMID:
26780512
24.

Neuritic complexity of hippocampal neurons depends on WIP-mediated mTORC1 and Abl family kinases activities.

Franco-Villanueva A, Wandosell F, Antón IM.

Brain Behav. 2015 Oct 3;5(11):e00359. doi: 10.1002/brb3.359. eCollection 2015 Nov.

25.

The hunt for brain Aβ oligomers by peripherally circulating multi-functional nanoparticles: Potential therapeutic approach for Alzheimer disease.

Mancini S, Minniti S, Gregori M, Sancini G, Cagnotto A, Couraud PO, Ordóñez-Gutiérrez L, Wandosell F, Salmona M, Re F.

Nanomedicine. 2016 Jan;12(1):43-52. doi: 10.1016/j.nano.2015.09.003. Epub 2015 Sep 26.

PMID:
26410276
26.

Increased migration of olfactory ensheathing cells secreting the Nogo receptor ectodomain over inhibitory substrates and lesioned spinal cord.

Reginensi D, Carulla P, Nocentini S, Seira O, Serra-Picamal X, Torres-Espín A, Matamoros-Angles A, Gavín R, Moreno-Flores MT, Wandosell F, Samitier J, Trepat X, Navarro X, del Río JA.

Cell Mol Life Sci. 2015 Jul;72(14):2719-37. doi: 10.1007/s00018-015-1869-3. Epub 2015 Feb 24.

27.

Secreted herpes simplex virus-2 glycoprotein G modifies NGF-TrkA signaling to attract free nerve endings to the site of infection.

Cabrera JR, Viejo-Borbolla A, Martinez-Martín N, Blanco S, Wandosell F, Alcamí A.

PLoS Pathog. 2015 Jan 22;11(1):e1004571. doi: 10.1371/journal.ppat.1004571. eCollection 2015 Jan.

28.

Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice.

Ordóñez-Gutiérrez L, Re F, Bereczki E, Ioja E, Gregori M, Andersen AJ, Antón M, Moghimi SM, Pei JJ, Masserini M, Wandosell F.

Nanomedicine. 2015 Feb;11(2):421-30. doi: 10.1016/j.nano.2014.09.015. Epub 2014 Nov 14.

29.

Peripheral amyloid levels present gender differences associated with aging in AβPP/PS1 mice.

Ordóñez-Gutiérrez L, Antón M, Wandosell F.

J Alzheimers Dis. 2015;44(4):1063-8. doi: 10.3233/JAD-141158.

30.

Cancer stem cell-like phenotype and survival are coordinately regulated by Akt/FoxO/Bim pathway.

Gargini R, Cerliani JP, Escoll M, Antón IM, Wandosell F.

Stem Cells. 2015 Mar;33(3):646-60. doi: 10.1002/stem.1904.

31.

Estradiol and Progesterone Administration After pMCAO Stimulates the Neurological Recovery and Reduces the Detrimental Effect of Ischemia Mainly in Hippocampus.

Perez-Alvarez MJ, Mateos L, Alonso A, Wandosell F.

Mol Neurobiol. 2015 Dec;52(3):1690-1703. doi: 10.1007/s12035-014-8963-7. Epub 2014 Nov 7.

PMID:
25377795
32.

Role of PrP(C) Expression in Tau Protein Levels and Phosphorylation in Alzheimer's Disease Evolution.

Vergara C, Ordóñez-Gutiérrez L, Wandosell F, Ferrer I, del Río JA, Gavín R.

Mol Neurobiol. 2015;51(3):1206-20. doi: 10.1007/s12035-014-8793-7. Epub 2014 Jun 26.

33.

ATP-P2X7 Receptor Modulates Axon Initial Segment Composition and Function in Physiological Conditions and Brain Injury.

Del Puerto A, Fronzaroli-Molinieres L, Perez-Alvarez MJ, Giraud P, Carlier E, Wandosell F, Debanne D, Garrido JJ.

Cereb Cortex. 2015 Aug;25(8):2282-94. doi: 10.1093/cercor/bhu035. Epub 2014 Mar 7.

34.

Hsp90 activity is necessary to acquire a proper neuronal polarization.

Benitez MJ, Sanchez-Ponce D, Garrido JJ, Wandosell F.

Biochim Biophys Acta. 2014 Feb;1843(2):245-52. doi: 10.1016/j.bbamcr.2013.11.013. Epub 2013 Nov 25.

35.

Neuronal and glial purinergic receptors functions in neuron development and brain disease.

Del Puerto A, Wandosell F, Garrido JJ.

Front Cell Neurosci. 2013 Oct 28;7:197. doi: 10.3389/fncel.2013.00197. Review.

36.

WIP regulates persistence of cell migration and ruffle formation in both mesenchymal and amoeboid modes of motility.

Banon-Rodriguez I, Saez de Guinoa J, Bernardini A, Ragazzini C, Fernandez E, Carrasco YR, Jones GE, Wandosell F, Anton IM.

PLoS One. 2013 Aug 7;8(8):e70364. doi: 10.1371/journal.pone.0070364. eCollection 2013.

37.

Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic mice.

Ordóñez-Gutiérrez L, Torres JM, Gavín R, Antón M, Arroba-Espinosa AI, Espinosa JC, Vergara C, Del Río JA, Wandosell F.

Neurobiol Aging. 2013 Dec;34(12):2793-804. doi: 10.1016/j.neurobiolaging.2013.05.019. Epub 2013 Jul 4.

PMID:
23831375
38.

Dysfunction of the PI3K-Akt-GSK-3 pathway is a common feature in cell culture and in vivo models of prion disease.

Simon D, Herva ME, Benitez MJ, Garrido JJ, Rojo AI, Cuadrado A, Torres JM, Wandosell F.

Neuropathol Appl Neurobiol. 2014 Apr;40(3):311-26. doi: 10.1111/nan.12066.

PMID:
23741998
39.

Neurogenic effects of β-amyloid in the choroid plexus epithelial cells in Alzheimer's disease.

Bolos M, Spuch C, Ordoñez-Gutierrez L, Wandosell F, Ferrer I, Carro E.

Cell Mol Life Sci. 2013 Aug;70(15):2787-97. doi: 10.1007/s00018-013-1300-x. Epub 2013 Mar 3.

PMID:
23455075
40.

Oestradiol signalling through the Akt-mTORC1-S6K1.

Varea O, Escoll M, Diez H, Garrido JJ, Wandosell F.

Biochim Biophys Acta. 2013 May;1833(5):1052-64. doi: 10.1016/j.bbamcr.2012.12.019. Epub 2013 Jan 4.

41.

GSK3 and β-catenin determines functional expression of sodium channels at the axon initial segment.

Tapia M, Del Puerto A, Puime A, Sánchez-Ponce D, Fronzaroli-Molinieres L, Pallas-Bazarra N, Carlier E, Giraud P, Debanne D, Wandosell F, Garrido JJ.

Cell Mol Life Sci. 2013 Jan;70(1):105-20. doi: 10.1007/s00018-012-1059-5. Epub 2012 Jul 5.

PMID:
22763697
42.

Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia.

Pérez-Álvarez MJ, Maza Mdel C, Anton M, Ordoñez L, Wandosell F.

J Neuroinflammation. 2012 Jul 2;9:157. doi: 10.1186/1742-2094-9-157.

43.

Specific roles of Akt iso forms in apoptosis and axon growth regulation in neurons.

Diez H, Garrido JJ, Wandosell F.

PLoS One. 2012;7(4):e32715. doi: 10.1371/journal.pone.0032715. Epub 2012 Apr 11.

44.

Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation.

del Puerto A, Díaz-Hernández JI, Tapia M, Gomez-Villafuertes R, Benitez MJ, Zhang J, Miras-Portugal MT, Wandosell F, Díaz-Hernández M, Garrido JJ.

J Cell Sci. 2012 Jan 1;125(Pt 1):176-88. doi: 10.1242/jcs.091736. Epub 2012 Jan 16.

45.

Myelin-associated proteins block the migration of olfactory ensheathing cells: an in vitro study using single-cell tracking and traction force microscopy.

Nocentini S, Reginensi D, Garcia S, Carulla P, Moreno-Flores MT, Wandosell F, Trepat X, Bribian A, del Río JA.

Cell Mol Life Sci. 2012 May;69(10):1689-703. doi: 10.1007/s00018-011-0893-1. Epub 2011 Dec 29.

PMID:
22205212
46.

Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies.

Medina M, Garrido JJ, Wandosell FG.

Front Mol Neurosci. 2011 Oct 5;4:24. doi: 10.3389/fnmol.2011.00024. eCollection 2011.

47.

WIP is a negative regulator of neuronal maturation and synaptic activity.

Franco A, Knafo S, Banon-Rodriguez I, Merino-Serrais P, Fernaud-Espinosa I, Nieto M, Garrido JJ, Esteban JA, Wandosell F, Anton IM.

Cereb Cortex. 2012 May;22(5):1191-202. doi: 10.1093/cercor/bhr199. Epub 2011 Aug 1.

PMID:
21810783
48.

Oestradiol regulates β-catenin-mediated transcription in neurones.

Wandosell F, Varea O, Arevalo MA, Garcia-Segura LM.

J Neuroendocrinol. 2012 Jan;24(1):191-4. doi: 10.1111/j.1365-2826.2011.02186.x. Review.

PMID:
21722217
49.

Deconstructing GSK-3: The Fine Regulation of Its Activity.

Medina M, Wandosell F.

Int J Alzheimers Dis. 2011;2011:479249. doi: 10.4061/2011/479249. Epub 2011 Apr 28.

50.

Overcoming cell death and tau phosphorylation mediated by PI3K-inhibition: a cell assay to measure neuroprotection.

Simon D, Medina M, Avila J, Wandosell F.

CNS Neurol Disord Drug Targets. 2011 Mar;10(2):208-14. Review.

PMID:
21222634

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