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Items: 1 to 50 of 109

1.

Whole-exome sequencing identified a novel mutation of AURKC in a Chinese family with macrozoospermia.

Hua J, Wan YY.

J Assist Reprod Genet. 2018 Dec 29. doi: 10.1007/s10815-018-1374-3. [Epub ahead of print]

PMID:
30594972
2.

A Western diet, but not high fat and low sugar diet, predisposes mice to enhanced susceptibility to imiquimod-induced psoriasiform dermatitis.

Yu S, Wu X, Zhou Y, Sheng L, Jena PK, Han D, Wan YY, Hwang ST.

J Invest Dermatol. 2018 Dec 17. pii: S0022-202X(18)32941-5. doi: 10.1016/j.jid.2018.12.002. [Epub ahead of print] No abstract available.

PMID:
30571973
3.

Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer.

Jia Q, Wu W, Wang Y, Alexander PB, Sun C, Gong Z, Cheng JN, Sun H, Guan Y, Xia X, Yang L, Yi X, Wan YY, Wang H, He J, Futreal PA, Li QJ, Zhu B.

Nat Commun. 2018 Dec 18;9(1):5361. doi: 10.1038/s41467-018-07767-w.

4.

Mitochondrial Fission Is Required for Blue Light-Induced Apoptosis and Mitophagy in Retinal Neuronal R28 Cells.

Li JY, Zhang K, Xu D, Zhou WT, Fang WQ, Wan YY, Yan DD, Guo MY, Tao JX, Zhou WC, Yang F, Jiang LP, Han XJ.

Front Mol Neurosci. 2018 Nov 27;11:432. doi: 10.3389/fnmol.2018.00432. eCollection 2018.

5.

Intracellular Activation of Complement C3 Leads to PD-L1 Antibody Treatment Resistance by Modulating Tumor-Associated Macrophages.

Zha H, Wang X, Zhu Y, Chen D, Han X, Yang F, Gao J, Hu C, Shu C, Feng Y, Tan Y, Zhang J, Li Y, Wan YY, Guo B, Zhu B.

Cancer Immunol Res. 2018 Dec 4. doi: 10.1158/2326-6066.CIR-18-0272. [Epub ahead of print]

PMID:
30514794
6.

RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs.

Wu B, Zhang S, Guo Z, Wang G, Zhang G, Xie L, Lou J, Chen X, Wu D, Bergmeier W, Zheng J, Wan YY.

Immunity. 2018 Nov 20;49(5):886-898.e5. doi: 10.1016/j.immuni.2018.09.004. Epub 2018 Nov 13.

PMID:
30446383
7.

Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.

Kim TH, Yang YM, Han CY, Koo JH, Oh H, Kim SS, You BH, Choi YH, Park TS, Lee CH, Kurose H, Noureddin M, Seki E, Wan YY, Choi CS, Kim SG.

J Clin Invest. 2018 Dec 3;128(12):5587-5602. doi: 10.1172/JCI97831. Epub 2018 Nov 12.

8.

RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells.

Hu Y, French SW, Chau T, Liu HX, Sheng L, Wei F, Stondell J, Garcia JC, Du Y, Bowlus CL, Wan YY.

FASEB J. 2018 Sep 25:fj201801390R. doi: 10.1096/fj.201801390R. [Epub ahead of print]

PMID:
30252536
9.

Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease.

Mordaunt CE, Shibata NM, Kieffer DA, Czlonkowska A, Litwin T, Weiss KH, Gotthardt DN, Olson K, Wei D, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V.

Hum Mol Genet. 2018 Nov 15;27(22):3854-3869. doi: 10.1093/hmg/ddy262.

PMID:
30010856
10.

The effect of synbiotics Bifidobacterium infantis and milk oligosaccharides on shaping gut microbiota community structure and NASH treatment.

Jena PK, Sheng L, Nagar N, Wu C, Barile D, Mills DA, Wan YY.

Data Brief. 2018 May 24;19:1025-1029. doi: 10.1016/j.dib.2018.05.127. eCollection 2018 Aug.

11.

Obesity treatment by epigallocatechin-3-gallate-regulated bile acid signaling and its enriched Akkermansia muciniphila.

Sheng L, Jena PK, Liu HX, Hu Y, Nagar N, Bronner DN, Settles ML, Bäumler AJ, Wan YY.

FASEB J. 2018 Jun 8:fj201800370R. doi: 10.1096/fj.201800370R. [Epub ahead of print]

PMID:
29882708
12.

Synbiotics Bifidobacterium infantis and milk oligosaccharides are effective in reversing cancer-prone nonalcoholic steatohepatitis using western diet-fed FXR knockout mouse models.

Jena PK, Sheng L, Nagar N, Wu C, Barile D, Mills DA, Wan YY.

J Nutr Biochem. 2018 Jul;57:246-254. doi: 10.1016/j.jnutbio.2018.04.007. Epub 2018 Apr 25.

PMID:
29800811
13.

The genetic characteristics of congenital hypothyroidism in China by comprehensive screening of 21 candidate genes.

Sun F, Zhang JX, Yang CY, Gao GQ, Zhu WB, Han B, Zhang LL, Wan YY, Ye XP, Ma YR, Zhang MM, Yang L, Zhang QY, Liu W, Guo CC, Chen G, Zhao SX, Song KY, Song HD.

Eur J Endocrinol. 2018 Jun;178(6):623-633. doi: 10.1530/EJE-17-1017. Epub 2018 Apr 12.

14.

Erythromycin poudrage versus erythromycin slurry in the treatment of refractory spontaneous pneumothorax.

Zhai CC, Lin XS, Yao ZH, Liu QH, Zhu L, Lin DJ, Wan YY.

J Thorac Dis. 2018 Feb;10(2):757-765. doi: 10.21037/jtd.2018.01.48.

15.

Effects of 5HT1A Activation on Gating Profile Following 5HT Depletion in Rats Lacking Social Attachment Since Weanling.

Tai YM, Ko CY, Lin CC, Wan YY, Chung JY, Liu YP.

Psychiatry Investig. 2018 Feb;15(2):193-199. doi: 10.30773/pi.2017.05.14.2. Epub 2017 Nov 7.

16.

Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2.

Zhu Y, Zhou J, Feng Y, Chen L, Zhang L, Yang F, Zha H, Wang X, Han X, Shu C, Wan YY, Li QJ, Guo B, Zhu B.

Front Immunol. 2018 Jan 30;9:87. doi: 10.3389/fimmu.2018.00087. eCollection 2018.

17.

Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity.

Jena PK, Sheng L, Di Lucente J, Jin LW, Maezawa I, Wan YY.

FASEB J. 2018 May;32(5):2866-2877. doi: 10.1096/fj.201700984RR. Epub 2018 Jan 10.

PMID:
29401580
18.

The role of Cdk5-mediated Drp1 phosphorylation in Aβ1-42 induced mitochondrial fission and neuronal apoptosis.

Guo MY, Shang L, Hu YY, Jiang LP, Wan YY, Zhou QQ, Zhang K, Liao HF, Yi JL, Han XJ.

J Cell Biochem. 2018 Jun;119(6):4815-4825. doi: 10.1002/jcb.26680. Epub 2018 Mar 7.

PMID:
29345339
19.

Integrated network analysis to identify the key genes, transcription factors, and microRNAs involved in hepatocellular carcinoma.

Shi SQ, Ke JJ, Xu QS, Wu WQ, Wan YY.

Neoplasma. 2018;65(1):66-74. doi: 10.4149/neo_2018_161215N642.

PMID:
29322790
20.

Reversing SKI-SMAD4-mediated suppression is essential for TH17 cell differentiation.

Zhang S, Takaku M, Zou L, Gu AD, Chou WC, Zhang G, Wu B, Kong Q, Thomas SY, Serody JS, Chen X, Xu X, Wade PA, Cook DN, Ting JPY, Wan YY.

Nature. 2017 Nov 2;551(7678):105-109. doi: 10.1038/nature24283. Epub 2017 Oct 25.

21.

[Effect of BBG on Acute Graft-Versus-Host Disease in Mice after Allogeneic Hematopoietic Stem Cell Transplantation].

Zhong XM, Zhao K, Liu H, Wang XW, Feng Y, Zhong Q, Wan YY, Xu KL.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Oct;25(5):1550-1558. doi: 10.7534/j.issn.1009-2137.2017.05.048. Chinese.

PMID:
29070142
22.

Silencing of α-complex protein-2 reverses alcohol- and cytokine-induced fibrogenesis in hepatic stellate cells.

Liu H, Chen Z, Jin W, Barve A, Wan YY, Cheng K.

Liver Res. 2017 Jun;1(1):70-79. doi: 10.1016/j.livres.2017.05.003.

23.

[Screen astragalosides from Huangqi injections by LC-TOF-MS-based mass defect filtering approach].

Song HT, Li CY, Wan YY, Ding XS, Tan XY, Dai GL, Liu SJ, Ju WZ.

Zhongguo Zhong Yao Za Zhi. 2017 Feb;42(4):686-695. doi: 10.19540/j.cnki.cjcmm.20170103.017. Chinese.

PMID:
28959838
24.

Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation.

Sheng L, Jena PK, Hu Y, Liu HX, Nagar N, Kalanetra KM, French SW, French SW, Mills DA, Wan YY.

J Pathol. 2017 Dec;243(4):431-441. doi: 10.1002/path.4983. Epub 2017 Nov 1.

25.

Immune Cell Metabolism in Tumor Microenvironment.

Li Y, Wan YY, Zhu B.

Adv Exp Med Biol. 2017;1011:163-196. doi: 10.1007/978-94-024-1170-6_5.

PMID:
28875490
26.

Amyloid β-42 induces neuronal apoptosis by targeting mitochondria.

Han XJ, Hu YY, Yang ZJ, Jiang LP, Shi SL, Li YR, Guo MY, Wu HL, Wan YY.

Mol Med Rep. 2017 Oct;16(4):4521-4528. doi: 10.3892/mmr.2017.7203. Epub 2017 Aug 10.

27.

Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment.

Jena PK, Sheng L, Liu HX, Kalanetra KM, Mirsoian A, Murphy WJ, French SW, Krishnan VV, Mills DA, Wan YY.

Am J Pathol. 2017 Aug;187(8):1800-1813. doi: 10.1016/j.ajpath.2017.04.019. Epub 2017 Jul 12.

28.

Involvement of mitochondrial dynamics in the antineoplastic activity of cisplatin in murine leukemia L1210 cells.

Han XJ, Shi SL, Wei YF, Jiang LP, Guo MY, Wu HL, Wan YY.

Oncol Rep. 2017 Aug;38(2):985-992. doi: 10.3892/or.2017.5765. Epub 2017 Jun 28.

PMID:
28677814
29.

Urinary metabolomics reveals the therapeutic effect of HuangQi Injections in cisplatin-induced nephrotoxic rats.

Li CY, Song HT, Wang XX, Wan YY, Ding XS, Liu SJ, Dai GL, Liu YH, Ju WZ.

Sci Rep. 2017 Jun 15;7(1):3619. doi: 10.1038/s41598-017-03249-z.

30.

Genetic study of early-onset Graves' disease in the Chinese Han population.

Yuan FF, Ye XP, Liu W, Xue LQ, Ma YR, Zhang LL, Zhang MM, Sun F, Wan YY, Zhang QY, Zhao SX, Song HD; China Consortium for the Genetics of Autoimmune Thyroid Disease.

Clin Genet. 2018 Jan;93(1):103-110. doi: 10.1111/cge.13072. Epub 2017 Oct 9.

PMID:
28598035
31.

Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation.

Sheng L, Jena PK, Liu HX, Kalanetra KM, Gonzalez FJ, French SW, Krishnan VV, Mills DA, Wan YY.

Sci Rep. 2017 May 11;7(1):1748. doi: 10.1038/s41598-017-01576-9.

32.

Egr-1 regulates irradiation-induced autophagy through Atg4B to promote radioresistance in hepatocellular carcinoma cells.

Peng WX, Wan YY, Gong AH, Ge L, Jin J, Xu M, Wu CY.

Oncogenesis. 2017 Jan 30;6(1):e292. doi: 10.1038/oncsis.2016.91.

33.

IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo.

Brockmann L, Gagliani N, Steglich B, Giannou AD, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herkel J, Wan YY, Esplugues E, Battaglia M, Krebs CF, Flavell RA, Huber S.

J Immunol. 2017 Feb 1;198(3):1130-1141. doi: 10.4049/jimmunol.1601045. Epub 2016 Dec 21.

34.

BPTF Is Essential for T Cell Homeostasis and Function.

Wu B, Wang Y, Wang C, Wang GG, Wu J, Wan YY.

J Immunol. 2016 Dec 1;197(11):4325-4333. Epub 2016 Oct 31.

35.

Determination of Cadmium in Shrimp and Shell Fish Samples by Coprecipitation Enrichment with Mn(Ⅱ)-5-Br-PADAP Flame Atomic Absorption Spectrometry.

Chen QH, Wan YY, Li Q, Yao JX.

Guang Pu Xue Yu Guang Pu Fen Xi. 2016 Oct;36(10):3351-4. Chinese.

PMID:
30246987
36.

Value of microsurgical varicocelectomy for severe oligo-asthenospermia patients failed in fertilization assisted by in vitro fertilization.

Guo TH, Tong XH, Luo LH, Luan HB, Zhou GX, Wan YY.

Eur Rev Med Pharmacol Sci. 2016 May;20(9):1669-74.

37.

[Study on active constituents against Alzheimer's disease from Valeriana amurensis].

Wan YY, Wang CF, Wang QH, Xiao Y, Wang ZB, Kuang HX.

Zhongguo Zhong Yao Za Zhi. 2016 May;41(9):1649-1653. doi: 10.4268/cjcmm20160914. Chinese.

PMID:
28891614
38.

Novel Anthranilic Diamide Scaffolds Containing N-Substituted Phenylpyrazole as Potential Ryanodine Receptor Activators.

Liu JB, Li YX, Zhang XL, Hua XW, Wu CC, Wei W, Wan YY, Cheng DD, Xiong LX, Yang N, Song HB, Li ZM.

J Agric Food Chem. 2016 May 11;64(18):3697-704. doi: 10.1021/acs.jafc.6b00380. Epub 2016 May 3.

PMID:
27109555
39.

DCAF1 controls T-cell function via p53-dependent and -independent mechanisms.

Guo Z, Kong Q, Liu C, Zhang S, Zou L, Yan F, Whitmire JK, Xiong Y, Chen X, Wan YY.

Nat Commun. 2016 Jan 5;7:10307. doi: 10.1038/ncomms10307.

40.

Egr-1 promotes hypoxia-induced autophagy to enhance chemo-resistance of hepatocellular carcinoma cells.

Peng WX, Xiong EM, Ge L, Wan YY, Zhang CL, Du FY, Xu M, Bhat RA, Jin J, Gong AH.

Exp Cell Res. 2016 Jan 1;340(1):62-70. doi: 10.1016/j.yexcr.2015.12.006. Epub 2015 Dec 17.

PMID:
26708617
41.

[Neurofibromatosis complicated by acute lymphoblastic leukemia in a boy].

Wan YY, Zhng LP, Wu J, Wang B.

Zhongguo Dang Dai Er Ke Za Zhi. 2015 Oct;17(10):1140-1. Chinese. No abstract available.

42.

Polymorphism in miR-146a associated with clinical characteristics and outcomes in gastric cancer patients treated with adjuvant oxaliplatin and fluoropyrimidines.

Liao YQ, Liao YL, Li J, Peng LX, Wan YY, Zhong R.

Onco Targets Ther. 2015 Sep 16;8:2627-33. doi: 10.2147/OTT.S89635. eCollection 2015.

43.

Conjugation of toll-like receptor-7 agonist to gastric cancer antigen MG7-Ag exerts antitumor effects.

Wang XD, Gao NN, Diao YW, Liu Y, Gao D, Li W, Wan YY, Zhong JJ, Jin GY.

World J Gastroenterol. 2015 Jul 14;21(26):8052-60. doi: 10.3748/wjg.v21.i26.8052.

44.

Antitumor activity of chloroquine in combination with Cisplatin in human gastric cancer xenografts.

Zhang HQ, Fang N, Liu XM, Xiong SP, Liao YQ, Jin WJ, Song RF, Wan YY.

Asian Pac J Cancer Prev. 2015;16(9):3907-12.

45.

Mechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer Immunotherapy.

Gao J, Zhao L, Wan YY, Zhu B.

Int J Mol Sci. 2015 May 6;16(5):10267-80. doi: 10.3390/ijms160510267. Review.

46.
47.

A population-based cohort study of 394,401 children followed for 10 years exhibits sustained effectiveness of scoliosis screening.

Fong DY, Cheung KM, Wong YW, Wan YY, Lee CF, Lam TP, Cheng JC, Ng BK, Luk KD.

Spine J. 2015 May 1;15(5):825-33. doi: 10.1016/j.spinee.2015.01.019. Epub 2015 Jan 20.

PMID:
25615844
48.

MicroRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer.

Wang XW, Xi XQ, Wu J, Wan YY, Hui HX, Cao XF.

Oncol Rep. 2015 Mar;33(3):1402-10. doi: 10.3892/or.2015.3731. Epub 2015 Jan 19.

PMID:
25607234
49.

A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling.

Gu AD, Zhang S, Wang Y, Xiong H, Curtis TA, Wan YY.

Immunity. 2015 Jan 20;42(1):68-79. doi: 10.1016/j.immuni.2014.12.019. Epub 2014 Dec 25.

50.

Mitochondrial dynamics regulates hypoxia-induced migration and antineoplastic activity of cisplatin in breast cancer cells.

Han XJ, Yang ZJ, Jiang LP, Wei YF, Liao MF, Qian Y, Li Y, Huang X, Wang JB, Xin HB, Wan YY.

Int J Oncol. 2015 Feb;46(2):691-700. doi: 10.3892/ijo.2014.2781. Epub 2014 Nov 27.

PMID:
25434519

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