Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 121


Inhibition of Cdk8/Cdk19 Activity Promotes Treg Cell Differentiation and Suppresses Autoimmune Diseases.

Guo Z, Wang G, Lv Y, Wan YY, Zheng J.

Front Immunol. 2019 Aug 20;10:1988. doi: 10.3389/fimmu.2019.01988. eCollection 2019.


SKI and SMAD4 are essential for IL-21-induced Th17 differentiation.

Zhang S, Zhang G, Wan YY.

Mol Immunol. 2019 Oct;114:260-268. doi: 10.1016/j.molimm.2019.07.029. Epub 2019 Aug 6.


Prognostic impact of prognostic nutritional index in advanced (stage IIIB/IV) non-small cell lung cancer patients.

Li XL, Yao ZH, Wan YY, Mou XY, Ni YH, Sun EL, Zhang D, Lin DJ.

Neoplasma. 2019 Aug 4. pii: 190125N76. doi: 10.4149/neo_2019_190125N76. [Epub ahead of print]


NID2 can serve as a potential prognosis prediction biomarker and promotes the invasion and migration of gastric cancer.

Yu ZH, Wang YM, Jiang YZ, Ma SJ, Zhong Q, Wan YY, Wang XW.

Pathol Res Pract. 2019 Oct;215(10):152553. doi: 10.1016/j.prp.2019.152553. Epub 2019 Jul 23.


Safety and complications of medical thoracoscopy in the management of pleural diseases.

Wan YY, Zhai CC, Lin XS, Yao ZH, Liu QH, Zhu L, Li DZ, Li XL, Wang N, Lin DJ.

BMC Pulm Med. 2019 Jul 10;19(1):125. doi: 10.1186/s12890-019-0888-5.


Long-term Western diet intake leads to dysregulated bile acid signaling and dermatitis with Th2 and Th17 pathway features in mice.

Jena PK, Sheng L, Mcneil K, Chau TQ, Yu S, Kiuru M, Fung MA, Hwang ST, Wan YY.

J Dermatol Sci. 2019 Jul;95(1):13-20. doi: 10.1016/j.jdermsci.2019.05.007. Epub 2019 Jun 8.


Efficacy and safety of Hou Gu Mi Xi in patients with spleen qi deficiency syndrome who underwent radical gastrectomy for gastric cancer: protocol for a multicenter, randomized, double-blind, placebo-controlled trial.

Zhou X, Yan DM, Zhu WF, Liu WJ, Nie HY, Xu S, Jiang YP, Zhang KH, Fu Y, Wan YY, Yu XY, Li H, Sun X, Chen XF.

Trials. 2019 Jun 10;20(1):343. doi: 10.1186/s13063-019-3429-x.


Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation.

Zhou J, Huang S, Wang Z, Huang J, Xu L, Tang X, Wan YY, Li QJ, Symonds ALJ, Long H, Zhu B.

Nat Commun. 2019 Jun 3;10(1):2427. doi: 10.1038/s41467-019-10176-2.


Functional Effects of let-7g Expression in Colon Cancer Metastasis.

Chang CM, Wong HS, Huang CY, Hsu WL, Maio ZF, Chiu SJ, Tsai YT, Chen BK, Wan YY, Wang JY, Chang WC.

Cancers (Basel). 2019 Apr 6;11(4). pii: E489. doi: 10.3390/cancers11040489.


EZH2 Inhibitor GSK126 Suppresses Antitumor Immunity by Driving Production of Myeloid-Derived Suppressor Cells.

Huang S, Wang Z, Zhou J, Huang J, Zhou L, Luo J, Wan YY, Long H, Zhu B.

Cancer Res. 2019 Apr 15;79(8):2009-2020. doi: 10.1158/0008-5472.CAN-18-2395. Epub 2019 Feb 8.


Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers.

Mordaunt CE, Kieffer DA, Shibata NM, Członkowska A, Litwin T, Weiss KH, Zhu Y, Bowlus CL, Sarkar S, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V.

Epigenetics Chromatin. 2019 Feb 1;12(1):10. doi: 10.1186/s13072-019-0255-z.


A Weighted Genetic Risk Score Using Known Susceptibility Variants to Predict Graves Disease Risk.

Ma YR, Zhao SX, Li L, Sun F, Ye XP, Yuan FF, Jiang D, Zhou Z, Zhang QY, Wan YY, Zhang GY, Wu J, Zhang RJ, Fang Y, Song HD.

J Clin Endocrinol Metab. 2019 Jun 1;104(6):2121-2130. doi: 10.1210/jc.2018-01551.


Precision dietary supplementation based on personal gut microbiota.

Wan YY, Jena PK.

Nat Rev Gastroenterol Hepatol. 2019 Apr;16(4):204-206. doi: 10.1038/s41575-019-0108-z. No abstract available.


Whole-exome sequencing identified a novel mutation of AURKC in a Chinese family with macrozoospermia.

Hua J, Wan YY.

J Assist Reprod Genet. 2019 Mar;36(3):529-534. doi: 10.1007/s10815-018-1374-3. Epub 2018 Dec 29.


Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer.

Jia Q, Wu W, Wang Y, Alexander PB, Sun C, Gong Z, Cheng JN, Sun H, Guan Y, Xia X, Yang L, Yi X, Wan YY, Wang H, He J, Futreal PA, Li QJ, Zhu B.

Nat Commun. 2018 Dec 18;9(1):5361. doi: 10.1038/s41467-018-07767-w.


Mitochondrial Fission Is Required for Blue Light-Induced Apoptosis and Mitophagy in Retinal Neuronal R28 Cells.

Li JY, Zhang K, Xu D, Zhou WT, Fang WQ, Wan YY, Yan DD, Guo MY, Tao JX, Zhou WC, Yang F, Jiang LP, Han XJ.

Front Mol Neurosci. 2018 Nov 27;11:432. doi: 10.3389/fnmol.2018.00432. eCollection 2018.


Intracellular Activation of Complement C3 Leads to PD-L1 Antibody Treatment Resistance by Modulating Tumor-Associated Macrophages.

Zha H, Wang X, Zhu Y, Chen D, Han X, Yang F, Gao J, Hu C, Shu C, Feng Y, Tan Y, Zhang J, Li Y, Wan YY, Guo B, Zhu B.

Cancer Immunol Res. 2019 Feb;7(2):193-207. doi: 10.1158/2326-6066.CIR-18-0272. Epub 2018 Dec 4.


RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs.

Wu B, Zhang S, Guo Z, Wang G, Zhang G, Xie L, Lou J, Chen X, Wu D, Bergmeier W, Zheng J, Wan YY.

Immunity. 2018 Nov 20;49(5):886-898.e5. doi: 10.1016/j.immuni.2018.09.004. Epub 2018 Nov 13.


Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.

Kim TH, Yang YM, Han CY, Koo JH, Oh H, Kim SS, You BH, Choi YH, Park TS, Lee CH, Kurose H, Noureddin M, Seki E, Wan YY, Choi CS, Kim SG.

J Clin Invest. 2018 Dec 3;128(12):5587-5602. doi: 10.1172/JCI97831. Epub 2018 Nov 12.


RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells.

Hu Y, French SW, Chau T, Liu HX, Sheng L, Wei F, Stondell J, Garcia JC, Du Y, Bowlus CL, Wan YY.

FASEB J. 2019 Feb;33(2):2314-2326. doi: 10.1096/fj.201801390R. Epub 2018 Sep 25.


Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease.

Mordaunt CE, Shibata NM, Kieffer DA, Czlonkowska A, Litwin T, Weiss KH, Gotthardt DN, Olson K, Wei D, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V.

Hum Mol Genet. 2018 Nov 15;27(22):3854-3869. doi: 10.1093/hmg/ddy262.


The effect of synbiotics Bifidobacterium infantis and milk oligosaccharides on shaping gut microbiota community structure and NASH treatment.

Jena PK, Sheng L, Nagar N, Wu C, Barile D, Mills DA, Wan YY.

Data Brief. 2018 May 24;19:1025-1029. doi: 10.1016/j.dib.2018.05.127. eCollection 2018 Aug.


Obesity treatment by epigallocatechin-3-gallate-regulated bile acid signaling and its enriched Akkermansia muciniphila.

Sheng L, Jena PK, Liu HX, Hu Y, Nagar N, Bronner DN, Settles ML, Bäumler AJ, Wan YY.

FASEB J. 2018 Jun 8:fj201800370R. doi: 10.1096/fj.201800370R. [Epub ahead of print]


Synbiotics Bifidobacterium infantis and milk oligosaccharides are effective in reversing cancer-prone nonalcoholic steatohepatitis using western diet-fed FXR knockout mouse models.

Jena PK, Sheng L, Nagar N, Wu C, Barile D, Mills DA, Wan YY.

J Nutr Biochem. 2018 Jul;57:246-254. doi: 10.1016/j.jnutbio.2018.04.007. Epub 2018 Apr 25.


The genetic characteristics of congenital hypothyroidism in China by comprehensive screening of 21 candidate genes.

Sun F, Zhang JX, Yang CY, Gao GQ, Zhu WB, Han B, Zhang LL, Wan YY, Ye XP, Ma YR, Zhang MM, Yang L, Zhang QY, Liu W, Guo CC, Chen G, Zhao SX, Song KY, Song HD.

Eur J Endocrinol. 2018 Jun;178(6):623-633. doi: 10.1530/EJE-17-1017. Epub 2018 Apr 12.


Erythromycin poudrage versus erythromycin slurry in the treatment of refractory spontaneous pneumothorax.

Zhai CC, Lin XS, Yao ZH, Liu QH, Zhu L, Lin DJ, Wan YY.

J Thorac Dis. 2018 Feb;10(2):757-765. doi: 10.21037/jtd.2018.01.48.


Effects of 5HT1A Activation on Gating Profile Following 5HT Depletion in Rats Lacking Social Attachment Since Weanling.

Tai YM, Ko CY, Lin CC, Wan YY, Chung JY, Liu YP.

Psychiatry Investig. 2018 Feb;15(2):193-199. doi: 10.30773/pi.2017.05.14.2. Epub 2017 Nov 7.


Control of Intestinal Inflammation, Colitis-Associated Tumorigenesis, and Macrophage Polarization by Fibrinogen-Like Protein 2.

Zhu Y, Zhou J, Feng Y, Chen L, Zhang L, Yang F, Zha H, Wang X, Han X, Shu C, Wan YY, Li QJ, Guo B, Zhu B.

Front Immunol. 2018 Jan 30;9:87. doi: 10.3389/fimmu.2018.00087. eCollection 2018.


Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity.

Jena PK, Sheng L, Di Lucente J, Jin LW, Maezawa I, Wan YY.

FASEB J. 2018 May;32(5):2866-2877. doi: 10.1096/fj.201700984RR. Epub 2018 Jan 10.


The role of Cdk5-mediated Drp1 phosphorylation in Aβ1-42 induced mitochondrial fission and neuronal apoptosis.

Guo MY, Shang L, Hu YY, Jiang LP, Wan YY, Zhou QQ, Zhang K, Liao HF, Yi JL, Han XJ.

J Cell Biochem. 2018 Jun;119(6):4815-4825. doi: 10.1002/jcb.26680. Epub 2018 Mar 7.


Integrated network analysis to identify the key genes, transcription factors, and microRNAs involved in hepatocellular carcinoma.

Shi SQ, Ke JJ, Xu QS, Wu WQ, Wan YY.

Neoplasma. 2018;65(1):66-74. doi: 10.4149/neo_2018_161215N642.


Reversing SKI-SMAD4-mediated suppression is essential for TH17 cell differentiation.

Zhang S, Takaku M, Zou L, Gu AD, Chou WC, Zhang G, Wu B, Kong Q, Thomas SY, Serody JS, Chen X, Xu X, Wade PA, Cook DN, Ting JPY, Wan YY.

Nature. 2017 Nov 2;551(7678):105-109. doi: 10.1038/nature24283. Epub 2017 Oct 25.


[Effect of BBG on Acute Graft-Versus-Host Disease in Mice after Allogeneic Hematopoietic Stem Cell Transplantation].

Zhong XM, Zhao K, Liu H, Wang XW, Feng Y, Zhong Q, Wan YY, Xu KL.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Oct;25(5):1550-1558. doi: 10.7534/j.issn.1009-2137.2017.05.048. Chinese.


Silencing of α-complex protein-2 reverses alcohol- and cytokine-induced fibrogenesis in hepatic stellate cells.

Liu H, Chen Z, Jin W, Barve A, Wan YY, Cheng K.

Liver Res. 2017 Jun;1(1):70-79. doi: 10.1016/j.livres.2017.05.003.


[Screen astragalosides from Huangqi injections by LC-TOF-MS-based mass defect filtering approach].

Song HT, Li CY, Wan YY, Ding XS, Tan XY, Dai GL, Liu SJ, Ju WZ.

Zhongguo Zhong Yao Za Zhi. 2017 Feb;42(4):686-695. doi: 10.19540/j.cnki.cjcmm.20170103.017. Chinese.


Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation.

Sheng L, Jena PK, Hu Y, Liu HX, Nagar N, Kalanetra KM, French SW, French SW, Mills DA, Wan YY.

J Pathol. 2017 Dec;243(4):431-441. doi: 10.1002/path.4983. Epub 2017 Nov 1.


Immune Cell Metabolism in Tumor Microenvironment.

Li Y, Wan YY, Zhu B.

Adv Exp Med Biol. 2017;1011:163-196. doi: 10.1007/978-94-024-1170-6_5. Review.


Amyloid β-42 induces neuronal apoptosis by targeting mitochondria.

Han XJ, Hu YY, Yang ZJ, Jiang LP, Shi SL, Li YR, Guo MY, Wu HL, Wan YY.

Mol Med Rep. 2017 Oct;16(4):4521-4528. doi: 10.3892/mmr.2017.7203. Epub 2017 Aug 10.


Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment.

Jena PK, Sheng L, Liu HX, Kalanetra KM, Mirsoian A, Murphy WJ, French SW, Krishnan VV, Mills DA, Wan YY.

Am J Pathol. 2017 Aug;187(8):1800-1813. doi: 10.1016/j.ajpath.2017.04.019. Epub 2017 Jul 12. Erratum in: Am J Pathol. 2017 Nov;187(11):2617.


Involvement of mitochondrial dynamics in the antineoplastic activity of cisplatin in murine leukemia L1210 cells.

Han XJ, Shi SL, Wei YF, Jiang LP, Guo MY, Wu HL, Wan YY.

Oncol Rep. 2017 Aug;38(2):985-992. doi: 10.3892/or.2017.5765. Epub 2017 Jun 28.


Urinary metabolomics reveals the therapeutic effect of HuangQi Injections in cisplatin-induced nephrotoxic rats.

Li CY, Song HT, Wang XX, Wan YY, Ding XS, Liu SJ, Dai GL, Liu YH, Ju WZ.

Sci Rep. 2017 Jun 15;7(1):3619. doi: 10.1038/s41598-017-03249-z.


Genetic study of early-onset Graves' disease in the Chinese Han population.

Yuan FF, Ye XP, Liu W, Xue LQ, Ma YR, Zhang LL, Zhang MM, Sun F, Wan YY, Zhang QY, Zhao SX, Song HD; China Consortium for the Genetics of Autoimmune Thyroid Disease.

Clin Genet. 2018 Jan;93(1):103-110. doi: 10.1111/cge.13072. Epub 2017 Oct 9.


Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation.

Sheng L, Jena PK, Liu HX, Kalanetra KM, Gonzalez FJ, French SW, Krishnan VV, Mills DA, Wan YY.

Sci Rep. 2017 May 11;7(1):1748. doi: 10.1038/s41598-017-01576-9.


Egr-1 regulates irradiation-induced autophagy through Atg4B to promote radioresistance in hepatocellular carcinoma cells.

Peng WX, Wan YY, Gong AH, Ge L, Jin J, Xu M, Wu CY.

Oncogenesis. 2017 Jan 30;6(1):e292. doi: 10.1038/oncsis.2016.91.


IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo.

Brockmann L, Gagliani N, Steglich B, Giannou AD, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herkel J, Wan YY, Esplugues E, Battaglia M, Krebs CF, Flavell RA, Huber S.

J Immunol. 2017 Feb 1;198(3):1130-1141. doi: 10.4049/jimmunol.1601045. Epub 2016 Dec 21.


BPTF Is Essential for T Cell Homeostasis and Function.

Wu B, Wang Y, Wang C, Wang GG, Wu J, Wan YY.

J Immunol. 2016 Dec 1;197(11):4325-4333. Epub 2016 Oct 31.


Determination of Cadmium in Shrimp and Shell Fish Samples by Coprecipitation Enrichment with Mn(Ⅱ)-5-Br-PADAP Flame Atomic Absorption Spectrometry.

Chen QH, Wan YY, Li Q, Yao JX.

Guang Pu Xue Yu Guang Pu Fen Xi. 2016 Oct;36(10):3351-4. Chinese.


Value of microsurgical varicocelectomy for severe oligo-asthenospermia patients failed in fertilization assisted by in vitro fertilization.

Guo TH, Tong XH, Luo LH, Luan HB, Zhou GX, Wan YY.

Eur Rev Med Pharmacol Sci. 2016 May;20(9):1669-74.


[Study on active constituents against Alzheimer's disease from Valeriana amurensis].

Wan YY, Wang CF, Wang QH, Xiao Y, Wang ZB, Kuang HX.

Zhongguo Zhong Yao Za Zhi. 2016 May;41(9):1649-1653. doi: 10.4268/cjcmm20160914. Chinese.


Novel Anthranilic Diamide Scaffolds Containing N-Substituted Phenylpyrazole as Potential Ryanodine Receptor Activators.

Liu JB, Li YX, Zhang XL, Hua XW, Wu CC, Wei W, Wan YY, Cheng DD, Xiong LX, Yang N, Song HB, Li ZM.

J Agric Food Chem. 2016 May 11;64(18):3697-704. doi: 10.1021/acs.jafc.6b00380. Epub 2016 May 3.


Supplemental Content

Support Center