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Radiation-Induced Skin Fibrosis: Pathogenesis, Current Treatment Options, and Emerging Therapeutics.

Borrelli MR, Shen AH, Lee GK, Momeni A, Longaker MT, Wan DC.

Ann Plast Surg. 2019 Oct;83(4S Suppl 1):S59-S64. doi: 10.1097/SAP.0000000000002098.


Skeletal Stem Cell-Schwann Cell Circuitry in Mandibular Repair.

Jones RE, Salhotra A, Robertson KS, Ransom RC, Foster DS, Shah HN, Quarto N, Wan DC, Longaker MT.

Cell Rep. 2019 Sep 10;28(11):2757-2766.e5. doi: 10.1016/j.celrep.2019.08.021.


Discussion: Adipose-Derived Stem Cells and Ceiling Culture-Derived Preadipocytes Cultured from Subcutaneous Fat Tissue Differ in Their Epigenetic Characteristics and Osteogenic Potential.

Borrelli MR, Longaker MT, Wan DC.

Plast Reconstr Surg. 2019 Sep;144(3):656-657. doi: 10.1097/PRS.0000000000005914. No abstract available.


Acellular Dermal Matrix Reduces Myofibroblast Presence in the Breast Capsule.

Tevlin R, Borrelli MR, Irizarry D, Nguyen D, Wan DC, Momeni A.

Plast Reconstr Surg Glob Open. 2019 May 17;7(5):e2213. doi: 10.1097/GOX.0000000000002213. eCollection 2019 May.


Identifying risk factors for postoperative major complications in staged implant-based breast reconstruction with AlloDerm.

Remington AC, Gurtner GC, Wan DC, Nguyen D, Momeni A.

Breast J. 2019 Jul;25(4):597-603. doi: 10.1111/tbj.13299. Epub 2019 May 13.


The Spectrum of Scarring in Craniofacial Wound Repair.

desJardins-Park HE, Mascharak S, Chinta MS, Wan DC, Longaker MT.

Front Physiol. 2019 Mar 29;10:322. doi: 10.3389/fphys.2019.00322. eCollection 2019. Review.


Pro-Fibrotic CD26-Positive Fibroblasts are Present in Greater Abundance in Breast Capsule Tissue of Irradiated Breasts.

Borrelli MR, Irizzary D, Patel RA, Nguyen D, Momeni A, Longaker MT, Wan DC.

Aesthet Surg J. 2019 Apr 11. pii: sjz109. doi: 10.1093/asj/sjz109. [Epub ahead of print]


Fat Chance: The Rejuvenation of Irradiated Skin.

Borrelli MR, Patel RA, Sokol J, Nguyen D, Momeni A, Longaker MT, Wan DC.

Plast Reconstr Surg Glob Open. 2019 Feb 5;7(2):e2092. doi: 10.1097/GOX.0000000000002092. eCollection 2019 Feb.


Fat Grafting into Younger Recipients Improves Volume Retention in an Animal Model.

Chung NN, Ransom RC, Blackshear CP, Irizarry DM, Yen D, Momeni A, Lee GK, Nguyen DH, Longaker MT, Wan DC.

Plast Reconstr Surg. 2019 Apr;143(4):1067-1075. doi: 10.1097/PRS.0000000000005483.


Discussion: CRISPR Craft: DNA Editing the Reconstructive Ladder.

Hu MS, Longaker MT, Wan DC.

Plast Reconstr Surg. 2018 Nov;142(5):1365-1366. doi: 10.1097/PRS.0000000000004949. No abstract available.


Honey bee Royalactin unlocks conserved pluripotency pathway in mammals.

Wan DC, Morgan SL, Spencley AL, Mariano N, Chang EY, Shankar G, Luo Y, Li TH, Huh D, Huynh SK, Garcia JM, Dovey CM, Lumb J, Liu L, Brown KV, Bermudez A, Luong R, Zeng H, Mascetti VL, Pitteri SJ, Wang J, Tu H, Quarta M, Sebastiano V, Nusse R, Rando TA, Carette JE, Bazan JF, Wang KC.

Nat Commun. 2018 Dec 4;9(1):5078. doi: 10.1038/s41467-018-06256-4.


Reply: Deferoxamine Preconditioning of Irradiated Tissue Improves Perfusion and Fat Graft Retention.

Wan DC.

Plast Reconstr Surg. 2018 Dec;142(6):978e. doi: 10.1097/PRS.0000000000005028. No abstract available.


In Vitro and In Vivo Osteogenic Differentiation of Human Adipose-Derived Stromal Cells.

Marshall CD, Brett EA, Moore AL, Wan DC, Longaker MT.

Methods Mol Biol. 2019;1891:9-18. doi: 10.1007/978-1-4939-8904-1_2.


Mechanoresponsive stem cells acquire neural crest fate in jaw regeneration.

Ransom RC, Carter AC, Salhotra A, Leavitt T, Marecic O, Murphy MP, Lopez ML, Wei Y, Marshall CD, Shen EZ, Jones RE, Sharir A, Klein OD, Chan CKF, Wan DC, Chang HY, Longaker MT.

Nature. 2018 Nov;563(7732):514-521. doi: 10.1038/s41586-018-0650-9. Epub 2018 Oct 24.


Author Correction: Genetic dissection of clonal lineage relationships with hydroxytamoxifen liposomes.

Ransom RC, Foster DS, Salhotra A, Jones RE, Marshall CD, Leavitt T, Murphy MP, Moore AL, Blackshear CP, Brett EA, Wan DC, Longaker MT.

Nat Commun. 2018 Oct 19;9(1):4411. doi: 10.1038/s41467-018-06927-2.


Overexpression of CXCR4 synergizes with LL-37 in the metastasis of breast cancer cells.

Pan WL, Wang Y, Hao Y, Wong JH, Chan WC, Wan DC, Ng TB.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3837-3846. doi: 10.1016/j.bbadis.2018.09.008. Epub 2018 Sep 9.


Identification of the Human Skeletal Stem Cell.

Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, Leavitt T, Lu WJ, Nguyen A, Conley SD, Salhotra A, Ambrosi TH, Borrelli MR, Siebel T, Chan K, Schallmoser K, Seita J, Sahoo D, Goodnough H, Bishop J, Gardner M, Majeti R, Wan DC, Goodman S, Weissman IL, Chang HY, Longaker MT.

Cell. 2018 Sep 20;175(1):43-56.e21. doi: 10.1016/j.cell.2018.07.029.


Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue.

Blackshear CP, Borrelli MR, Shen EZ, Ransom RC, Chung NN, Vistnes SM, Irizarry D, Nazerali R, Momeni A, Longaker MT, Wan DC.

Tissue Eng Part C Methods. 2018 Oct;24(10):566-577. doi: 10.1089/ten.TEC.2018.0154.


Determining the impact of sarcopenia on postoperative complications after ventral hernia repair.

Barnes LA, Li AY, Wan DC, Momeni A.

J Plast Reconstr Aesthet Surg. 2018 Sep;71(9):1260-1268. doi: 10.1016/j.bjps.2018.05.013. Epub 2018 Jun 15.


Discovery of 4,5-Dihydro-1H-thieno[2',3':2,3]thiepino [4,5-c]pyrazole-3-carboxamide Derivatives as the Potential Epidermal Growth Factor Receptors for Tyrosine Kinase Inhibitors.

Ke J, Lu Q, Wang X, Sun R, Jin Z, Zhan X, Hu J, Wan DC, Hu C.

Molecules. 2018 Aug 8;23(8). pii: E1980. doi: 10.3390/molecules23081980.


Pathway Analysis of Gene Expression in Murine Fetal and Adult Wounds.

Hu MS, Hong WX, Januszyk M, Walmsley GG, Luan A, Maan ZN, Moshrefi S, Tevlin R, Wan DC, Gurtner GC, Longaker MT, Lorenz HP.

Adv Wound Care (New Rochelle). 2018 Aug 1;7(8):262-275. doi: 10.1089/wound.2017.0779.


Genetic dissection of clonal lineage relationships with hydroxytamoxifen liposomes.

Ransom RC, Foster DS, Salhotra A, Jones RE, Marshall CD, Leavitt T, Murphy MP, Moore AL, Blackshear CP, Brett EA, Wan DC, Longaker MT.

Nat Commun. 2018 Jul 30;9(1):2971. doi: 10.1038/s41467-018-05436-6. Erratum in: Nat Commun. 2018 Oct 19;9(1):4411.


Mesenchymal Stromal Cells and Cutaneous Wound Healing: A Comprehensive Review of the Background, Role, and Therapeutic Potential.

Hu MS, Borrelli MR, Lorenz HP, Longaker MT, Wan DC.

Stem Cells Int. 2018 May 20;2018:6901983. doi: 10.1155/2018/6901983. eCollection 2018. Review.


Opinions on Authorship: A Survey of Plastic Surgery Residents and Fellows.

Momeni A, Hunter C, Li AY, Safa B, Wan DC, Kneser U.

Ann Plast Surg. 2018 Jun;80(6):660-663. doi: 10.1097/SAP.0000000000001396.


Identification of influenza polymerase inhibitors targeting C-terminal domain of PA through surface plasmon resonance screening.

Lo CY, Li OT, Tang WP, Hu C, Wang GX, Ngo JC, Wan DC, Poon LL, Shaw PC.

Sci Rep. 2018 Feb 2;8(1):2280. doi: 10.1038/s41598-018-20772-9.


Noncoding RNAs in Wound Healing: A New and Vast Frontier.

Luan A, Hu MS, Leavitt T, Brett EA, Wang KC, Longaker MT, Wan DC.

Adv Wound Care (New Rochelle). 2018 Jan 1;7(1):19-27. doi: 10.1089/wound.2017.0765. Review.


An Improved Humanized Mouse Model for Excisional Wound Healing Using Double Transgenic Mice.

Hu MS, Cheng J, Borrelli MR, Leavitt T, Walmsley GG, Zielins ER, Hong WX, Cheung ATM, Duscher D, Maan ZN, Irizarry DM, Stephan B, Parsa FD, Wan DC, Gurtner GC, Lorenz HP, Longaker MT.

Adv Wound Care (New Rochelle). 2018 Jan 1;7(1):11-17. doi: 10.1089/wound.2017.0772.


Human Adipose-Derived Stromal Cell Isolation Methods and Use in Osteogenic and Adipogenic In Vivo Applications.

Brett E, Tevlin R, McArdle A, Seo EY, Chan CKF, Wan DC, Longaker MT.

Curr Protoc Stem Cell Biol. 2017 Nov 15;43:2H.1.1-2H.1.15. doi: 10.1002/cpsc.41.


Deferoxamine Preconditioning of Irradiated Tissue Improves Perfusion and Fat Graft Retention.

Flacco J, Chung N, Blackshear CP, Irizarry D, Momeni A, Lee GK, Nguyen D, Gurtner GC, Longaker MT, Wan DC.

Plast Reconstr Surg. 2018 Mar;141(3):655-665. doi: 10.1097/PRS.0000000000004167.


Synthesis, ╬▓ -catenin Translocation Capability and ALP Activation Activity of 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives.

Hou S, Xu H, Hu J, Hou J, Wang Y, Jin Z, Wan DCC, Hu C.

Med Chem. 2018;14(1):67-73. doi: 10.2174/1573406413666171002121443.


Impact of a Cleft and Craniofacial Center on an Academic Health System.

Pourtaheri N, Kearney A, Wan DC, Lakin GE.

Plast Reconstr Surg. 2017 Oct;140(4):587e-597e. doi: 10.1097/PRS.0000000000003822. Erratum in: Plast Reconstr Surg. 2018 May;141(5):1313.


Ultrasound-assisted liposuction provides a source for functional adipose-derived stromal cells.

Duscher D, Maan ZN, Luan A, Aitzetm├╝ller MM, Brett EA, Atashroo D, Whittam AJ, Hu MS, Walmsley GG, Houschyar KS, Schilling AF, Machens HG, Gurtner GC, Longaker MT, Wan DC.

Cytotherapy. 2017 Dec;19(12):1491-1500. doi: 10.1016/j.jcyt.2017.07.013. Epub 2017 Sep 13.


* Calvarial Defects: Cell-Based Reconstructive Strategies in the Murine Model.

Murphy MP, Quarto N, Longaker MT, Wan DC.

Tissue Eng Part C Methods. 2017 Dec;23(12):971-981. doi: 10.1089/ten.TEC.2017.0230. Epub 2017 Oct 4. Review.


Three-Dimensional Ultrasound Versus Computerized Tomography in Fat Graft Volumetric Analysis.

Blackshear CP, Rector MA, Chung NN, Irizarry DM, Flacco JS, Brett EA, Momeni A, Lee GK, Longaker MT, Wan DC.

Ann Plast Surg. 2018 Mar;80(3):293-296. doi: 10.1097/SAP.0000000000001183.


Cell-Based Soft Tissue Reconstruction in a Hydrogel Scaffold.

Blackshear CP, Flacco JS, Vistnes SM, Chung NN, Irizarry D, Brett EA, Yen DJ, Momeni A, Longaker MT, Wan DC.

Ann Plast Surg. 2017 Dec;79(6):618-622. doi: 10.1097/SAP.0000000000001194.


Is Distraction Osteogenesis of the Irradiated Craniofacial Skeleton Contraindicated?

Momeni A, Januszyk M, Wan DC.

J Craniofac Surg. 2017 Jul;28(5):1236-1241. doi: 10.1097/SCS.0000000000003683. Review.


The Role of Skeletal Stem Cells in the Reconstruction of Bone Defects.

Murphy MP, Irizarry D, Lopez M, Moore AL, Ransom RC, Longaker MT, Wan DC, Chan CKF.

J Craniofac Surg. 2017 Jul;28(5):1136-1141. doi: 10.1097/SCS.0000000000003893. Review.


Identification of influenza polymerase inhibitors targeting polymerase PB2 cap-binding domain through virtual screening.

Liu M, Lo CY, Wang G, Chow HF, Ngo JC, Wan DC, Poon LL, Shaw PC.

Antiviral Res. 2017 Aug;144:186-195. doi: 10.1016/j.antiviral.2017.06.009. Epub 2017 Jun 16.


Dynamic Rheology for the Prediction of Surgical Outcomes in Autologous Fat Grafting.

Luan A, Zielins ER, Wearda T, Atashroo DA, Blackshear CP, Raphel J, Brett EA, Flacco J, Alyono MC, Momeni A, Heilshorn S, Longaker MT, Wan DC.

Plast Reconstr Surg. 2017 Sep;140(3):517-524. doi: 10.1097/PRS.0000000000003578.


Isolation of CD248-expressing stromal vascular fraction for targeted improvement of wound healing.

Brett E, Zielins ER, Chin M, Januszyk M, Blackshear CP, Findlay M, Momeni A, Gurtner GC, Longaker MT, Wan DC.

Wound Repair Regen. 2017 May;25(3):414-422. doi: 10.1111/wrr.12542. Epub 2017 May 18.


A Review of Cell-Based Strategies for Soft Tissue Reconstruction.

Brett E, Chung N, Leavitt WT, Momeni A, Longaker MT, Wan DC.

Tissue Eng Part B Rev. 2017 Aug;23(4):336-346. doi: 10.1089/ten.TEB.2016.0455. Epub 2017 Apr 27. Review.


A novel selective VPAC2 agonist peptide-conjugated chitosan modified selenium nanoparticles with enhanced anti-type 2 diabetes synergy effects.

Zhao SJ, Wang DH, Li YW, Han L, Xiao X, Ma M, Wan DC, Hong A, Ma Y.

Int J Nanomedicine. 2017 Mar 20;12:2143-2160. doi: 10.2147/IJN.S130566. eCollection 2017.


Purified Adipose-Derived Stromal Cells Provide Superior Fat Graft Retention Compared with Unenriched Stromal Vascular Fraction.

Zielins ER, Brett EA, Blackshear CP, Flacco J, Ransom RC, Longaker MT, Wan DC.

Plast Reconstr Surg. 2017 Apr;139(4):911-914. doi: 10.1097/PRS.0000000000003165.


Discussion: Regeneration of Vascularized Corticocancellous Bone and Diploic Space Using Muscle-Derived Stem Cells: A Translational Biologic Alternative for Healing Critical Bone Defects.

Irizarry DM, Wan DC.

Plast Reconstr Surg. 2017 Apr;139(4):908-909. doi: 10.1097/PRS.0000000000003211. No abstract available.


Rapid Isolation of BMPR-IB+ Adipose-Derived Stromal Cells for Use in a Calvarial Defect Healing Model.

Marshall CD, Zielins ER, Brett EA, Blackshear CP, Hu MS, Leavitt T, Barnes LA, Lorenz HP, Longaker MT, Wan DC.

J Vis Exp. 2017 Feb 24;(120). doi: 10.3791/55120.


Magnetic Nanoparticle-Based Upregulation of B-Cell Lymphoma 2 Enhances Bone Regeneration.

Brett E, Zielins ER, Luan A, Ooi CC, Shailendra S, Atashroo D, Menon S, Blackshear C, Flacco J, Quarto N, Wang SX, Longaker MT, Wan DC.

Stem Cells Transl Med. 2017 Jan;6(1):151-160. doi: 10.5966/sctm.2016-0051. Epub 2016 Aug 2.


Biomimetics of Bone Implants: The Regenerative Road.

Brett E, Flacco J, Blackshear C, Longaker MT, Wan DC.

Biores Open Access. 2017 Jan 1;6(1):1-6. doi: 10.1089/biores.2016.0044. eCollection 2017. Review.


Excess Dermal Tissue Remodeling In Vivo: Does It Settle?

Leavitt T, Hu MS, Zielins ER, Barnes LA, Marshall CD, Wan DC, Lorenz HP, Gurtner GC, Longaker MT.

Plast Reconstr Surg. 2017 Feb;139(2):415e-424e. doi: 10.1097/PRS.0000000000003026.


Pharmacological rescue of diabetic skeletal stem cell niches.

Tevlin R, Seo EY, Marecic O, McArdle A, Tong X, Zimdahl B, Malkovskiy A, Sinha R, Gulati G, Li X, Wearda T, Morganti R, Lopez M, Ransom RC, Duldulao CR, Rodrigues M, Nguyen A, Januszyk M, Maan Z, Paik K, Yapa KS, Rajadas J, Wan DC, Gurtner GC, Snyder M, Beachy PA, Yang F, Goodman SB, Weissman IL, Chan CK, Longaker MT.

Sci Transl Med. 2017 Jan 11;9(372). pii: eaag2809. doi: 10.1126/scitranslmed.aag2809.


Commentary on: Adipose Stem Cell Function Maintained with Age: An Intra-Subject Study of Long-Term Cryopreserved Cells.

Irizarry D, Longaker MT, Wan DC.

Aesthet Surg J. 2017 Apr 1;37(4):464-465. doi: 10.1093/asj/sjw224. No abstract available.


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