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Items: 30


The Use of pMHCII Tetramer Technology for the Identification and Characterization of CD4+ T Cells.

Wambre E.

Methods Mol Biol. 2019;2020:153-164. doi: 10.1007/978-1-4939-9591-2_11.


Renal Cell Carcinoma (RCC) Tumors Display Large Expansion of Double Positive (DP) CD4+CD8+ T Cells With Expression of Exhaustion Markers.

Menard LC, Fischer P, Kakrecha B, Linsley PS, Wambre E, Liu MC, Rust BJ, Lee D, Penhallow B, Manjarrez Orduno N, Nadler SG.

Front Immunol. 2018 Nov 26;9:2728. doi: 10.3389/fimmu.2018.02728. eCollection 2018.


Heterogeneity of Ara h Component-Specific CD4 T Cell Responses in Peanut-Allergic Subjects.

Renand A, Farrington M, Whalen E, Wambre E, Bajzik V, Chinthrajah S, Nadeau KC, Kwok WW.

Front Immunol. 2018 Jun 25;9:1408. doi: 10.3389/fimmu.2018.01408. eCollection 2018.


Immune mechanisms of oral immunotherapy.

Kulis MD, Patil SU, Wambre E, Vickery BP.

J Allergy Clin Immunol. 2018 Feb;141(2):491-498. doi: 10.1016/j.jaci.2017.12.979. Epub 2017 Dec 26. Review.


Oral Tolerance Development and Maintenance.

Wambre E, Jeong D.

Immunol Allergy Clin North Am. 2018 Feb;38(1):27-37. doi: 10.1016/j.iac.2017.09.003. Epub 2017 Oct 26. Review.


Synchronous immune alterations mirror clinical response during allergen immunotherapy.

Renand A, Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR.

J Allergy Clin Immunol. 2018 May;141(5):1750-1760.e1. doi: 10.1016/j.jaci.2017.09.041. Epub 2017 Nov 9.


Erratum to: Human Immune Monitoring Techniques during Food Allergen Immunotherapy.

Rust BJ, Wambre E.

Curr Allergy Asthma Rep. 2017 Oct;17(10):71. doi: 10.1007/s11882-017-0736-8. No abstract available.


A phenotypically and functionally distinct human TH2 cell subpopulation is associated with allergic disorders.

Wambre E, Bajzik V, DeLong JH, O'Brien K, Nguyen QA, Speake C, Gersuk VH, DeBerg HA, Whalen E, Ni C, Farrington M, Jeong D, Robinson D, Linsley PS, Vickery BP, Kwok WW.

Sci Transl Med. 2017 Aug 2;9(401). pii: eaam9171. doi: 10.1126/scitranslmed.aam9171.


Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.

Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS.

J Immunol. 2017 Jul 1;199(1):323-335. doi: 10.4049/jimmunol.1700172. Epub 2017 May 31.


Human Immune Monitoring Techniques during Food Allergen Immunotherapy.

Rust BJ, Wambre E.

Curr Allergy Asthma Rep. 2017 Apr;17(4):22. doi: 10.1007/s11882-017-0689-y. Review. Erratum in: Curr Allergy Asthma Rep. 2017 Oct;17 (10 ):71.


Circulating innate lymphoid cells are differentially regulated in allergic and nonallergic subjects.

Lombardi V, Beuraud C, Neukirch C, Moussu H, Morizur L, Horiot S, Luce S, Wambre E, Linsley P, Chollet-Martin S, Baron-Bodo V, Aubier M, Moingeon P.

J Allergy Clin Immunol. 2016 Jul;138(1):305-308. doi: 10.1016/j.jaci.2015.12.1325. Epub 2016 Mar 4. No abstract available.


Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity.

Hinz D, Seumois G, Gholami AM, Greenbaum JA, Lane J, White B, Broide DH, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok WW, Peters B, Vijayanand P, Sette A.

Clin Exp Allergy. 2016 May;46(5):705-19. doi: 10.1111/cea.12692.


Effect of allergen-specific immunotherapy on CD4+ T cells.

Wambre E.

Curr Opin Allergy Clin Immunol. 2015 Dec;15(6):581-7. doi: 10.1097/ACI.0000000000000216. Review.


Chronic cat allergen exposure induces a TH2 cell-dependent IgG4 response related to low sensitization.

Renand A, Archila LD, McGinty J, Wambre E, Robinson D, Hales BJ, Thomas WR, Kwok WW.

J Allergy Clin Immunol. 2015 Dec;136(6):1627-1635.e13. doi: 10.1016/j.jaci.2015.07.031. Epub 2015 Sep 11.


Biomarkers for antigen immunotherapy in allergy and type 1 diabetes.

Odegard JM, Nepom GT, Wambre E.

Clin Immunol. 2015 Nov;161(1):44-50. doi: 10.1016/j.clim.2015.05.023. Epub 2015 Jun 27. Review.


Arginine kinase Pen m 2 as an important shrimp allergen recognized by TH2 cells.

Renand A, Newbrough S, Wambre E, DeLong JH, Robinson D, Kwok WW.

J Allergy Clin Immunol. 2014 Dec;134(6):1456-1459.e7. doi: 10.1016/j.jaci.2014.07.048. Epub 2014 Sep 12. No abstract available.


Grass-specific CD4(+) T-cells exhibit varying degrees of cross-reactivity, implications for allergen-specific immunotherapy.

Archila LD, DeLong JH, Wambre E, James EA, Robinson DM, Kwok WW.

Clin Exp Allergy. 2014 Jul;44(7):986-98. doi: 10.1111/cea.12324.


Specific immunotherapy modifies allergen-specific CD4(+) T-cell responses in an epitope-dependent manner.

Wambre E, DeLong JH, James EA, Torres-Chinn N, Pfützner W, Möbs C, Durham SR, Till SJ, Robinson D, Kwok WW.

J Allergy Clin Immunol. 2014 Mar;133(3):872-9.e7. doi: 10.1016/j.jaci.2013.10.054. Epub 2013 Dec 25.


Allergen-specific CD4+ T cell responses in peripheral blood do not predict the early onset of clinical efficacy during grass pollen sublingual immunotherapy.

Bonvalet M, Moussu H, Wambre E, Ricarte C, Horiot S, Rimaniol AC, Kwok WW, Horak F, de Beaumont O, Baron-Bodo V, Moingeon P.

Clin Exp Allergy. 2012 Dec;42(12):1745-55. doi: 10.1111/cea.12015.


Characterization of CD4+ T cell subsets in allergy.

Wambre E, James EA, Kwok WW.

Curr Opin Immunol. 2012 Dec;24(6):700-6. doi: 10.1016/j.coi.2012.07.009. Epub 2012 Aug 10. Review.


Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy.

Wambre E, DeLong JH, James EA, LaFond RE, Robinson D, Kwok WW.

J Allergy Clin Immunol. 2012 Feb;129(2):544-51, 551.e1-7. doi: 10.1016/j.jaci.2011.08.034. Epub 2011 Oct 5.


Ara h 1-reactive T cells in individuals with peanut allergy.

DeLong JH, Simpson KH, Wambre E, James EA, Robinson D, Kwok WW.

J Allergy Clin Immunol. 2011 May;127(5):1211-8.e3. doi: 10.1016/j.jaci.2011.02.028. Epub 2011 Apr 2.


Comparison between major histocompatibility complex class II tetramer staining and surface expression of activation markers for the detection of allergen-specific CD4⁺ T cells.

Bonvalet M, Wambre E, Moussu H, Horiot S, Kwok WW, Louise A, Ebo D, Hoarau C, Van Overtvelt L, Baron-Bodo V, Moingeon P.

Clin Exp Allergy. 2011 Jun;41(6):821-9. doi: 10.1111/j.1365-2222.2011.03708.x. Epub 2011 Mar 21.


Distinct characteristics of seasonal (Bet v 1) vs. perennial (Der p 1/Der p 2) allergen-specific CD4(+) T cell responses.

Wambre E, Bonvalet M, Bodo VB, Maillère B, Leclert G, Moussu H, Von Hofe E, Louise A, Balazuc AM, Ebo D, Hoarau C, Garcia G, Van Overtvelt L, Moingeon P.

Clin Exp Allergy. 2011 Feb;41(2):192-203. doi: 10.1111/j.1365-2222.2010.03641.x. Epub 2010 Nov 24.


Direct ex vivo analysis of allergen-specific CD4+ T cells.

Kwok WW, Roti M, Delong JH, Tan V, Wambre E, James EA, Robinson D.

J Allergy Clin Immunol. 2010 Jun;125(6):1407-1409.e1. doi: 10.1016/j.jaci.2010.03.037. No abstract available.


Production of native and modified recombinant Der p 1 molecules in tobacco plants.

Burtin D, Chabre H, Olagnier B, Didierlaurent A, Couret MN, Comeau D, Wambre E, Laparra H, Van Overtvelt L, Montandon F, Batard T, Jonval V, Lorphelin A, Merle C, Berrouet C, Parry L, Gomord V, Van Ree R, Moingeon P.

Clin Exp Allergy. 2009 May;39(5):760-70. doi: 10.1111/j.1365-2222.2009.03201.x. Epub 2009 Feb 18.


Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes".

De Groot AS, Moise L, McMurry JA, Wambre E, Van Overtvelt L, Moingeon P, Scott DW, Martin W.

Blood. 2008 Oct 15;112(8):3303-11. doi: 10.1182/blood-2008-02-138073. Epub 2008 Jul 25.


Assessment of Bet v 1-specific CD4+ T cell responses in allergic and nonallergic individuals using MHC class II peptide tetramers.

Van Overtvelt L, Wambre E, Maillère B, von Hofe E, Louise A, Balazuc AM, Bohle B, Ebo D, Leboulaire C, Garcia G, Moingeon P.

J Immunol. 2008 Apr 1;180(7):4514-22.


Single cell assessment of allergen-specific T cell responses with MHC class II peptide tetramers: methodological aspects.

Wambre E, Van Overtvelt L, Maillère B, Humphreys R, von Hofe E, Ferhat L, Ebo D, Moingeon P.

Int Arch Allergy Immunol. 2008;146(2):99-112. doi: 10.1159/000113513. Epub 2008 Jan 18.


Suspension-cultured BY-2 tobacco cells produce and mature immunologically active house dust mite allergens.

Lienard D, Tran Dinh O, van Oort E, Van Overtvelt L, Bonneau C, Wambre E, Bardor M, Cosette P, Didier-Laurent A, de Borne FD, Delon R, van Ree R, Moingeon P, Faye L, Gomord V.

Plant Biotechnol J. 2007 Jan;5(1):93-108.

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