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Items: 16


xTract: software for characterizing conformational changes of protein complexes by quantitative cross-linking mass spectrometry.

Walzthoeni T, Joachimiak LA, Rosenberger G, Röst HL, Malmström L, Leitner A, Frydman J, Aebersold R.

Nat Methods. 2015 Dec;12(12):1185-90. doi: 10.1038/nmeth.3631. Epub 2015 Oct 26.


The structural basis of substrate recognition by the eukaryotic chaperonin TRiC/CCT.

Joachimiak LA, Walzthoeni T, Liu CW, Aebersold R, Frydman J.

Cell. 2014 Nov 20;159(5):1042-1055. doi: 10.1016/j.cell.2014.10.042.


Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes.

Leitner A, Joachimiak LA, Unverdorben P, Walzthoeni T, Frydman J, Förster F, Aebersold R.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9455-60. doi: 10.1073/pnas.1320298111. Epub 2014 Jun 17.


A mass spectrometry-based hybrid method for structural modeling of protein complexes.

Politis A, Stengel F, Hall Z, Hernández H, Leitner A, Walzthoeni T, Robinson CV, Aebersold R.

Nat Methods. 2014 Apr;11(4):403-406. doi: 10.1038/nmeth.2841. Epub 2014 Feb 9.


Lysine-specific chemical cross-linking of protein complexes and identification of cross-linking sites using LC-MS/MS and the xQuest/xProphet software pipeline.

Leitner A, Walzthoeni T, Aebersold R.

Nat Protoc. 2014 Jan;9(1):120-37. doi: 10.1038/nprot.2013.168. Epub 2013 Dec 19.


Mass spectrometry supported determination of protein complex structure.

Walzthoeni T, Leitner A, Stengel F, Aebersold R.

Curr Opin Struct Biol. 2013 Apr;23(2):252-60. doi: 10.1016/ Epub 2013 Mar 20. Review.


Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry.

Herzog F, Kahraman A, Boehringer D, Mak R, Bracher A, Walzthoeni T, Leitner A, Beck M, Hartl FU, Ban N, Malmström L, Aebersold R.

Science. 2012 Sep 14;337(6100):1348-52. doi: 10.1126/science.1221483.


False discovery rate estimation for cross-linked peptides identified by mass spectrometry.

Walzthoeni T, Claassen M, Leitner A, Herzog F, Bohn S, Förster F, Beck M, Aebersold R.

Nat Methods. 2012 Sep;9(9):901-3. doi: 10.1038/nmeth.2103. Epub 2012 Jul 8.


The molecular architecture of the eukaryotic chaperonin TRiC/CCT.

Leitner A, Joachimiak LA, Bracher A, Mönkemeyer L, Walzthoeni T, Chen B, Pechmann S, Holmes S, Cong Y, Ma B, Ludtke S, Chiu W, Hartl FU, Aebersold R, Frydman J.

Structure. 2012 May 9;20(5):814-25. doi: 10.1016/j.str.2012.03.007. Epub 2012 Apr 12.


Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach.

Lasker K, Förster F, Bohn S, Walzthoeni T, Villa E, Unverdorben P, Beck F, Aebersold R, Sali A, Baumeister W.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1380-7. doi: 10.1073/pnas.1120559109. Epub 2012 Jan 23.


Expanding the chemical cross-linking toolbox by the use of multiple proteases and enrichment by size exclusion chromatography.

Leitner A, Reischl R, Walzthoeni T, Herzog F, Bohn S, Förster F, Aebersold R.

Mol Cell Proteomics. 2012 Mar;11(3):M111.014126. doi: 10.1074/mcp.M111.014126. Epub 2012 Jan 27.


Insights into EB1 structure and the role of its C-terminal domain for discriminating microtubule tips from the lattice.

Buey RM, Mohan R, Leslie K, Walzthoeni T, Missimer JH, Menzel A, Bjelic S, Bargsten K, Grigoriev I, Smal I, Meijering E, Aebersold R, Akhmanova A, Steinmetz MO.

Mol Biol Cell. 2011 Aug 15;22(16):2912-23. doi: 10.1091/mbc.E11-01-0017. Epub 2011 Jul 7.


Structural analysis of vascular endothelial growth factor receptor-2/ligand complexes by small-angle X-ray solution scattering.

Kisko K, Brozzo MS, Missimer J, Schleier T, Menzel A, Leppänen VM, Alitalo K, Walzthoeni T, Aebersold R, Ballmer-Hofer K.

FASEB J. 2011 Sep;25(9):2980-6. doi: 10.1096/fj.11-185397. Epub 2011 May 25.


Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.

Bohn S, Beck F, Sakata E, Walzthoeni T, Beck M, Aebersold R, Förster F, Baumeister W, Nickell S.

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20992-7. doi: 10.1073/pnas.1015530107. Epub 2010 Nov 22.


Probing native protein structures by chemical cross-linking, mass spectrometry, and bioinformatics.

Leitner A, Walzthoeni T, Kahraman A, Herzog F, Rinner O, Beck M, Aebersold R.

Mol Cell Proteomics. 2010 Aug;9(8):1634-49. doi: 10.1074/mcp.R000001-MCP201. Epub 2010 Mar 31. Review.


Identification of cross-linked peptides from large sequence databases.

Rinner O, Seebacher J, Walzthoeni T, Mueller LN, Beck M, Schmidt A, Mueller M, Aebersold R.

Nat Methods. 2008 Apr;5(4):315-8. doi: 10.1038/nmeth.1192. Epub 2008 Mar 9. Erratum in: Nat Methods. 2008 Aug;5(8):748.

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