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Hazard from Himalayan glacier lake outburst floods.

Veh G, Korup O, Walz A.

Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):907-912. doi: 10.1073/pnas.1914898117. Epub 2019 Dec 30.


Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay.

Walz A, Leroy D, Andenmatten N, Mäser P, Wittlin S.

Malar J. 2019 Dec 18;18(1):427. doi: 10.1186/s12936-019-3056-8.


Novel therapy for pediatric and adolescent kidney cancer.

Walz AL, Fernandez CV, Geller JI.

Cancer Metastasis Rev. 2019 Dec 6. doi: 10.1007/s10555-019-09822-4. [Epub ahead of print] Review.


Synthesis and μ-Opioid Activity of the Primary Metabolites of Carfentanil.

Hsu FL, Walz AJ, Myslinski JM, Kong L, Feasel MG, Goralski TDP, Rose T, Cooper NJ, Roughley N, Timperley CM.

ACS Med Chem Lett. 2019 Oct 16;10(11):1568-1572. doi: 10.1021/acsmedchemlett.9b00404. eCollection 2019 Nov 14.


Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer.

Bouhaddou M, Yu LJ, Lunardi S, Stamatelos SK, Mack F, Gallo JM, Birtwistle MR, Walz AC.

Clin Transl Sci. 2019 Nov 15. doi: 10.1111/cts.12727. [Epub ahead of print]


Stochastic Protein Alkylation by Antimalarial Peroxides.

Jourdan J, Walz A, Matile H, Schmidt A, Wu J, Wang X, Dong Y, Vennerstrom JL, Schmidt RS, Wittlin S, Mäser P.

ACS Infect Dis. 2019 Dec 13;5(12):2067-2075. doi: 10.1021/acsinfecdis.9b00264. Epub 2019 Dec 2.


Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies.

Walz A, Lukka PB, Pearce C, Creissen E, Braunstein M, Hickey AJ, Meibohm B, Gonzalez-Juarrero M.

Tuberculosis (Edinb). 2019 Jul;117:52-55. doi: 10.1016/ Epub 2019 Jun 6.


Climatic and socioeconomic effects on land cover changes across Europe: Does protected area designation matter?

Hellwig N, Walz A, Markovic D.

PLoS One. 2019 Jul 17;14(7):e0219374. doi: 10.1371/journal.pone.0219374. eCollection 2019.


Case 3: Anisocoria in a 5-year old Girl.

McEachern W, Walz A, Dantuluri K, Dulek D, Betters K.

Pediatr Rev. 2019 Jul;40(7):366-368. doi: 10.1542/pir.2018-0132. No abstract available.


Nature's contributions to people in mountains: A review.

Martín-López B, Leister I, Lorenzo Cruz P, Palomo I, Grêt-Regamey A, Harrison PA, Lavorel S, Locatelli B, Luque S, Walz A.

PLoS One. 2019 Jun 11;14(6):e0217847. doi: 10.1371/journal.pone.0217847. eCollection 2019.


Synthesis and Molecular Properties of Nerve Agent Reactivator HLö-7 Dimethanesulfonate.

Hsu FL, Bae SY, McGuire J, Anderson DR, Bester SM, Height JJ, Pegan SD, Walz AJ.

ACS Med Chem Lett. 2019 Mar 28;10(5):761-766. doi: 10.1021/acsmedchemlett.9b00021. eCollection 2019 May 9.


Testicular wedge biopsy for fertility preservation in children at significant risk for azoospermia after gonadotoxic therapy.

Corkum KS, Lautz TB, Johnson EK, Reimann MB, Walz AL, Lockart BA, Brannigan RE, ValliPulaski H, Orwig KE, Rowell EE.

J Pediatr Surg. 2019 Sep;54(9):1901-1905. doi: 10.1016/j.jpedsurg.2019.01.055. Epub 2019 Feb 21.


Laparoscopic unilateral oophorectomy for ovarian tissue cryopreservation in children.

Rowell EE, Corkum KS, Lautz TB, Laronda MM, Walz AL, Madonna MB, Lockart BA, Reynolds M.

J Pediatr Surg. 2019 Mar;54(3):543-549. doi: 10.1016/j.jpedsurg.2018.06.005. Epub 2018 Jun 9.


Prolonged response to sorafenib in a patient with refractory metastatic osteosarcoma and a somatic PDGFRA D846V mutation.

Armstrong AE, Walterhouse DO, Leavey PJ, Reichek J, Walz AL.

Pediatr Blood Cancer. 2019 Jan;66(1):e27493. doi: 10.1002/pbc.27493. Epub 2018 Oct 14.


[Lys5,MeLeu9,Nle10]-NKA(4-10) Elicits NK2 Receptor-Mediated Micturition and Defecation, and NK1 Receptor-Mediated Emesis and Hypotension, in Conscious Dogs.

Rupniak NMJ, Katofiasc M, Walz A, Thor KB, Burgard EC.

J Pharmacol Exp Ther. 2018 Jul;366(1):136-144. doi: 10.1124/jpet.118.248765. Epub 2018 May 4.


Using observational facial descriptors to infer pain in persons with and without dementia.

Lautenbacher S, Walz AL, Kunz M.

BMC Geriatr. 2018 Apr 11;18(1):88. doi: 10.1186/s12877-018-0773-8.


Teaching High-Value Care in Pediatrics: A National Survey of Current Practices and Guide for Future Curriculum Development.

Tchou MJ, Walz A, Burgener E, Schroeder A, Blankenburg R.

J Grad Med Educ. 2017 Dec;9(6):741-747. doi: 10.4300/JGME-D-17-00139.1.


PKPD modeling of acquired resistance to anti-cancer drug treatment.

Eigenmann MJ, Frances N, Lavé T, Walz AC.

J Pharmacokinet Pharmacodyn. 2017 Dec;44(6):617-630. doi: 10.1007/s10928-017-9553-x. Epub 2017 Oct 31.


A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.

Gadd S, Huff V, Walz AL, Ooms AHAG, Armstrong AE, Gerhard DS, Smith MA, Auvil JMG, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Hermida LC, Davidsen T, Gesuwan P, Ma Y, Zong Z, Mungall AJ, Moore RA, Marra MA, Dome JS, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Ross N, Gastier-Foster JM, Arold ST, Perlman EJ.

Nat Genet. 2017 Oct;49(10):1487-1494. doi: 10.1038/ng.3940. Epub 2017 Aug 21.


Testing socio-cultural valuation methods of ecosystem services to explain land use preferences.

Schmidt K, Walz A, Martín-López B, Sachse R.

Ecosyst Serv. 2017 Aug;26(Pt A):270-288. doi: 10.1016/j.ecoser.2017.07.001.


Activity Based Protein Profiling Leads to Identification of Novel Protein Targets for Nerve Agent VX.

Carmany D, Walz AJ, Hsu FL, Benton B, Burnett D, Gibbons J, Noort D, Glaros T, Sekowski JW.

Chem Res Toxicol. 2017 Apr 17;30(4):1076-1084. doi: 10.1021/acs.chemrestox.6b00438. Epub 2017 Mar 16.


Vulnerability of European freshwater catchments to climate change.

Markovic D, Carrizo SF, Kärcher O, Walz A, David JNW.

Glob Chang Biol. 2017 Sep;23(9):3567-3580. doi: 10.1111/gcb.13657. Epub 2017 Mar 8.


Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer.

Walz A, Ugolkov A, Chandra S, Kozikowski A, Carneiro BA, O'Halloran TV, Giles FJ, Billadeau DD, Mazar AP.

Clin Cancer Res. 2017 Apr 15;23(8):1891-1897. doi: 10.1158/1078-0432.CCR-15-2240. Epub 2017 Jan 4. Review.


Translational PK/PD modeling to increase probability of success in drug discovery and early development.

Lavé T, Caruso A, Parrott N, Walz A.

Drug Discov Today Technol. 2016 Sep - Dec;21-22:27-34. doi: 10.1016/j.ddtec.2016.11.005. Epub 2016 Dec 10. Review.


Neuropilin-1 and the Positions of Glomeruli in the Mouse Olfactory Bulb.

Zapiec B, Bressel OC, Khan M, Walz A, Mombaerts P.

eNeuro. 2016 Nov 1;3(5). pii: ENEURO.0123-16.2016. eCollection 2016 Sep-Oct.


Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group.

Ooms AH, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Ma Y, Zong Z, Mungall AJ, Moore RA, Marra MA, Huff V, Dome JS, Chi YY, Tian J, Geller JI, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Walz AL, van den Heuvel-Eibrink MM, de Krijger RR, Ross N, Gastier-Foster JM, Perlman EJ.

Clin Cancer Res. 2016 Nov 15;22(22):5582-5591. doi: 10.1158/1078-0432.CCR-16-0985. Epub 2016 Oct 4.


Combining Nonclinical Experiments with Translational PKPD Modeling to Differentiate Erlotinib and Gefitinib.

Eigenmann MJ, Frances N, Hoffmann G, Lavé T, Walz AC.

Mol Cancer Ther. 2016 Dec;15(12):3110-3119. Epub 2016 Sep 16.


First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors.

Menke-van der Houven van Oordt CW, Gomez-Roca C, van Herpen C, Coveler AL, Mahalingam D, Verheul HM, van der Graaf WT, Christen R, Rüttinger D, Weigand S, Cannarile MA, Heil F, Brewster M, Walz AC, Nayak TK, Guarin E, Meresse V, Le Tourneau C.

Oncotarget. 2016 Nov 29;7(48):80046-80058. doi: 10.18632/oncotarget.11098.


Crowdsourcing: It Matters Who the Crowd Are. The Impacts of between Group Variations in Recording Land Cover.

Comber A, Mooney P, Purves RS, Rocchini D, Walz A.

PLoS One. 2016 Jul 26;11(7):e0158329. doi: 10.1371/journal.pone.0158329. eCollection 2016.


Increased ventral premotor cortex recruitment after arm training in an fMRI study with subacute stroke patients.

Horn U, Roschka S, Eyme K, Walz AD, Platz T, Lotze M.

Behav Brain Res. 2016 Jul 15;308:152-9. doi: 10.1016/j.bbr.2016.04.040. Epub 2016 Apr 22.


Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia.

Vey N, Delaunay J, Martinelli G, Fiedler W, Raffoux E, Prebet T, Gomez-Roca C, Papayannidis C, Kebenko M, Paschka P, Christen R, Guarin E, Bröske AM, Baehner M, Brewster M, Walz AC, Michielin F, Runza V, Meresse V, Recher C.

Oncotarget. 2016 May 31;7(22):32532-42. doi: 10.18632/oncotarget.8687.


Case 2: Persistent Stridor After Upper Respiratory Tract Infection in a 2-month-old Boy.

Walz A, Goel V, Kim J.

Pediatr Rev. 2016 Mar;37(3):123-5. doi: 10.1542/pir.2015-0126. No abstract available.


Recent developments in using mechanistic cardiac modelling for drug safety evaluation.

Davies MR, Wang K, Mirams GR, Caruso A, Noble D, Walz A, Lavé T, Schuler F, Singer T, Polonchuk L.

Drug Discov Today. 2016 Jun;21(6):924-38. doi: 10.1016/j.drudis.2016.02.003. Epub 2016 Feb 15. Review.


Influence of molecular size on tissue distribution of antibody fragments.

Li Z, Krippendorff BF, Sharma S, Walz AC, Lavé T, Shah DK.

MAbs. 2016;8(1):113-9. doi: 10.1080/19420862.2015.1111497. Epub 2015 Oct 23.


Adverse childhood experiences and trauma informed care: the future of health care.

Oral R, Ramirez M, Coohey C, Nakada S, Walz A, Kuntz A, Benoit J, Peek-Asa C.

Pediatr Res. 2016 Jan;79(1-2):227-33. doi: 10.1038/pr.2015.197. Epub 2015 Oct 13. Review.


Developing Exposure/Response Models for Anticancer Drug Treatment: Special Considerations.

Mould DR, Walz AC, Lave T, Gibbs JP, Frame B.

CPT Pharmacometrics Syst Pharmacol. 2015 Jan;4(1):e00016. doi: 10.1002/psp4.16. Epub 2015 Jan 21.


Model-based assessment of erlotinib effect in vitro measured by real-time cell analysis.

Benay S, Meille C, Kustermann S, Walter I, Walz A, Gonsard PA, Pietilae E, Kratochwil N, Iliadis A, Roth A, Lave T.

J Pharmacokinet Pharmacodyn. 2015 Jun;42(3):275-85. doi: 10.1007/s10928-015-9415-3. Epub 2015 Mar 31.


Effects of climate extremes on the terrestrial carbon cycle: concepts, processes and potential future impacts.

Frank D, Reichstein M, Bahn M, Thonicke K, Frank D, Mahecha MD, Smith P, van der Velde M, Vicca S, Babst F, Beer C, Buchmann N, Canadell JG, Ciais P, Cramer W, Ibrom A, Miglietta F, Poulter B, Rammig A, Seneviratne SI, Walz A, Wattenbach M, Zavala MA, Zscheischler J.

Glob Chang Biol. 2015 Aug;21(8):2861-80. doi: 10.1111/gcb.12916. Epub 2015 May 12. Review.


Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.

Walz AL, Ooms A, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Bowlby R, Brooks D, Ma Y, Mungall AJ, Moore RA, Schein J, Marra MA, Huff V, Dome JS, Chi YY, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Jafari N, Ross N, Gastier-Foster JM, Perlman EJ.

Cancer Cell. 2015 Feb 9;27(2):286-97. doi: 10.1016/j.ccell.2015.01.003. Erratum in: Cancer Cell. 2015 Mar 9;27(3):426. Guidry Auvil, Jamie M [corrected to Guidry Auvil, Jaime M].


Use of allogeneic stem cell transplantation for moderate-severe Glanzmann thrombasthenia.

Walz A, Lenzen A, Curtis B, Canner J, Schneiderman J.

Platelets. 2015;26(7):702-4. doi: 10.3109/09537104.2014.987225. Epub 2014 Dec 30.


Quantitative measurement of retinal hemorrhages in suspected victims of child abuse.

Longmuir SQ, Oral R, Walz AE, Kemp PS, Ryba J, Zimmerman BM, Abramoff MD.

J AAPOS. 2014 Dec;18(6):529-33. doi: 10.1016/j.jaapos.2014.07.175. Epub 2014 Nov 13.


In vivo identification of eugenol-responsive and muscone-responsive mouse odorant receptors.

McClintock TS, Adipietro K, Titlow WB, Breheny P, Walz A, Mombaerts P, Matsunami H.

J Neurosci. 2014 Nov 19;34(47):15669-78. doi: 10.1523/JNEUROSCI.3625-14.2014.


Changes in cortical, cerebellar and basal ganglia representation after comprehensive long term unilateral hand motor training.

Walz AD, Doppl K, Kaza E, Roschka S, Platz T, Lotze M.

Behav Brain Res. 2015 Feb 1;278:393-403. doi: 10.1016/j.bbr.2014.08.044. Epub 2014 Sep 3.


Lynx1 supports neuronal health in the mouse dorsal striatum during aging: an ultrastructural investigation.

Kobayashi A, Parker RL, Wright AP, Brahem H, Ku P, Oliver KM, Walz A, Lester HA, Miwa JM.

J Mol Neurosci. 2014 Jul;53(3):525-36. doi: 10.1007/s12031-014-0352-1. Epub 2014 Jul 17.


The efficacy of short-term psycho-oncological interventions for women with gynaecological cancer: a randomized study.

Goerling U, Jaeger C, Walz A, Stickel A, Mangler M, van der Meer E.

Oncology. 2014;87(2):114-24. doi: 10.1159/000362818. Epub 2014 Jul 4.


[True and virtual risks of travellers].

Hatz C, Walz A, Genton B, Behrens R.

Rev Med Suisse. 2014 May 7;10(429):1001-3. French.


Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy.

Ries CH, Cannarile MA, Hoves S, Benz J, Wartha K, Runza V, Rey-Giraud F, Pradel LP, Feuerhake F, Klaman I, Jones T, Jucknischke U, Scheiblich S, Kaluza K, Gorr IH, Walz A, Abiraj K, Cassier PA, Sica A, Gomez-Roca C, de Visser KE, Italiano A, Le Tourneau C, Delord JP, Levitsky H, Blay JY, Rüttinger D.

Cancer Cell. 2014 Jun 16;25(6):846-59. doi: 10.1016/j.ccr.2014.05.016. Epub 2014 Jun 2.


Preclinical optimization of MDM2 antagonist scheduling for cancer treatment by using a model-based approach.

Higgins B, Glenn K, Walz A, Tovar C, Filipovic Z, Hussain S, Lee E, Kolinsky K, Tannu S, Adames V, Garrido R, Linn M, Meille C, Heimbrook D, Vassilev L, Packman K.

Clin Cancer Res. 2014 Jul 15;20(14):3742-52. doi: 10.1158/1078-0432.CCR-14-0460. Epub 2014 May 8.


Climate extremes and the carbon cycle.

Reichstein M, Bahn M, Ciais P, Frank D, Mahecha MD, Seneviratne SI, Zscheischler J, Beer C, Buchmann N, Frank DC, Papale D, Rammig A, Smith P, Thonicke K, van der Velde M, Vicca S, Walz A, Wattenbach M.

Nature. 2013 Aug 15;500(7462):287-95. doi: 10.1038/nature12350.


[Accidents in travellers - the hidden epidemic].

Walz A, Hatz C.

Ther Umsch. 2013 Jun;70(6):318-22. doi: 10.1024/0040-5930/a000410. German.


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