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Items: 28


The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma.

Truini A, Starrett JH, Stewart T, Ashtekar K, Walther Z, Wurtz A, Lu D, Park JH, DeVeaux M, Song X, Gettinger S, Zelterman D, Lemmon MA, Goldberg SB, Politi K.

Clin Cancer Res. 2019 Jun 10. doi: 10.1158/1078-0432.CCR-19-0780. [Epub ahead of print]


Endogenous development of Cystoisospora belli in intestinal and biliary epithelium of humans.

Dubey JP, Evason KJ, Walther Z.

Parasitology. 2019 Jun;146(7):865-872. doi: 10.1017/S003118201900012X. Epub 2019 Mar 12.


Yale Cancer Center Precision Medicine Tumor Board: two patients, one targeted therapy, different outcomes.

Cecchini M, Walther Z, Sklar JL, Bindra RS, Petrylak DP, Eder JP, Goldberg SB.

Lancet Oncol. 2018 Jan;19(1):23-24. doi: 10.1016/S1470-2045(17)30916-6. No abstract available.


Introduction to the Yale Precision Medicine Tumor Board.

Cecchini M, Walther Z, Sklar JL, Bindra RS, Petrylak DP, Eder JP, Goldberg SB.

Lancet Oncol. 2018 Jan;19(1):19-20. doi: 10.1016/S1470-2045(17)30919-1. No abstract available.


Congenital Extrahepatic Portosystemic Shunt (Abernethy Malformation Type Ib) With Associated Hepatocellular Carcinoma: Case Report and Literature Review.

Benedict M, Rodriguez-Davalos M, Emre S, Walther Z, Morotti R.

Pediatr Dev Pathol. 2017 Jul-Aug;20(4):354-362. doi: 10.1177/1093526616686458. Epub 2017 Jan 25. Review.


A Long-Term Survivor of Metastatic Pancreatic Adenocarcinoma: Free of Recurrence 12 Years After Treatment of Oligometastatic Disease.

Stahl JM, Walther Z, Chang BW, Hochster HS, Johung KL.

Cureus. 2017 Feb 2;9(2):e1007. doi: 10.7759/cureus.1007.


Analytical Validation of the Next-Generation Sequencing Assay for a Nationwide Signal-Finding Clinical Trial: Molecular Analysis for Therapy Choice Clinical Trial.

Lih CJ, Harrington RD, Sims DJ, Harper KN, Bouk CH, Datta V, Yau J, Singh RR, Routbort MJ, Luthra R, Patel KP, Mantha GS, Krishnamurthy S, Ronski K, Walther Z, Finberg KE, Canosa S, Robinson H, Raymond A, Le LP, McShane LM, Polley EC, Conley BA, Doroshow JH, Iafrate AJ, Sklar JL, Hamilton SR, Williams PM.

J Mol Diagn. 2017 Mar;19(2):313-327. doi: 10.1016/j.jmoldx.2016.10.007. Epub 2017 Feb 7.


Congenital Extrahepatic Portosystemic Shunt (Abernethy Malformation Type Ib) with Associated Hepatocellular Carcinoma: Case report and Literature Review.

Benedict M, Rodriguez-Davalos M, Emre S, Walther Z, Morotti RA.

Pediatr Dev Pathol. 2016 Apr 26. [Epub ahead of print]


Acquired resistance of EGFR-mutant lung adenocarcinomas to afatinib plus cetuximab is associated with activation of mTORC1.

Pirazzoli V, Nebhan C, Song X, Wurtz A, Walther Z, Cai G, Zhao Z, Jia P, de Stanchina E, Shapiro EM, Gale M, Yin R, Horn L, Carbone DP, Stephens PJ, Miller V, Gettinger S, Pao W, Politi K.

Cell Rep. 2014 May 22;7(4):999-1008. doi: 10.1016/j.celrep.2014.04.014. Epub 2014 May 9.


Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.

de Bruin EC, Cowell C, Warne PH, Jiang M, Saunders RE, Melnick MA, Gettinger S, Walther Z, Wurtz A, Heynen GJ, Heideman DA, Gómez-Román J, García-Castaño A, Gong Y, Ladanyi M, Varmus H, Bernards R, Smit EF, Politi K, Downward J.

Cancer Discov. 2014 May;4(5):606-19. doi: 10.1158/2159-8290.CD-13-0741. Epub 2014 Feb 17.


MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice.

Hoshi N, Schenten D, Nish SA, Walther Z, Gagliani N, Flavell RA, Reizis B, Shen Z, Fox JG, Iwasaki A, Medzhitov R.

Nat Commun. 2012;3:1120. doi: 10.1038/ncomms2113.


Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice.

Woo DK, Green PD, Santos JH, D'Souza AD, Walther Z, Martin WD, Christian BE, Chandel NS, Shadel GS.

Am J Pathol. 2012 Jan;180(1):24-31. doi: 10.1016/j.ajpath.2011.10.003. Epub 2011 Nov 3.


Molecular pathology of hepatic neoplasms: classification and clinical significance.

Walther Z, Jain D.

Patholog Res Int. 2011 Apr 7;2011:403929. doi: 10.4061/2011/403929.


Molecular tumor profiling for prediction of response to anticancer therapies.

Walther Z, Sklar J.

Cancer J. 2011 Mar-Apr;17(2):71-9. doi: 10.1097/PPO.0b013e318212dd6d. Review.


CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity.

Lozovatsky L, Abayasekara N, Piawah S, Walther Z.

Mol Biol Cell. 2009 Nov;20(21):4489-99. doi: 10.1091/mbc.E09-04-0280. Epub 2009 Sep 2.


Isospora cholangiopathy: case study with histologic characterization and molecular confirmation.

Walther Z, Topazian MD.

Hum Pathol. 2009 Sep;40(9):1342-6. doi: 10.1016/j.humpath.2009.01.020. Epub 2009 May 17.


A PDZ-binding motif controls basolateral targeting of syndecan-1 along the biosynthetic pathway in polarized epithelial cells.

Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I.

Traffic. 2008 Nov;9(11):1915-24. doi: 10.1111/j.1600-0854.2008.00805.x. Epub 2008 Jul 30.


The unique-5 and -6 motifs of ZO-1 regulate tight junction strand localization and scaffolding properties.

Fanning AS, Little BP, Rahner C, Utepbergenov D, Walther Z, Anderson JM.

Mol Biol Cell. 2007 Mar;18(3):721-31. Epub 2006 Dec 20.


Ileostomy adenocarcinomas in the setting of ulcerative colitis.

Achneck HE, Wong IY, Kim PJ, Fernandes MA, Walther Z, Seymour NE, Jain D.

J Clin Gastroenterol. 2005 May-Jun;39(5):396-400. Review.


COX-2 and angiogenesis in gastric cancer.

Walther Z.

J Clin Gastroenterol. 2003 Jul;37(1):4-6. No abstract available.


Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells.

Cohen AR, Woods DF, Marfatia SM, Walther Z, Chishti AH, Anderson JM.

J Cell Biol. 1998 Jul 13;142(1):129-38. Erratum in: J Cell Biol 1998 Aug 24;142(4):following 1156. Wood DF [corrected to Woods DF].


The uni chromosome of Chlamydomonas: histone genes and nucleosome structure.

Walther Z, Hall JL.

Nucleic Acids Res. 1995 Sep 25;23(18):3756-63.


The Chlamydomonas FLA10 gene encodes a novel kinesin-homologous protein.

Walther Z, Vashishtha M, Hall JL.

J Cell Biol. 1994 Jul;126(1):175-88.


slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system.

Rothberg JM, Hartley DA, Walther Z, Artavanis-Tsakonas S.

Cell. 1988 Dec 23;55(6):1047-59.


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