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Items: 1 to 50 of 179

2.

Decoding and targeting the molecular basis of MACC1-driven metastatic spread: Lessons from big data mining and clinical-experimental approaches.

Budczies J, Kluck K, Walther W, Stein U.

Semin Cancer Biol. 2019 Aug 17. pii: S1044-579X(19)30200-7. doi: 10.1016/j.semcancer.2019.08.010. [Epub ahead of print] Review.

PMID:
31430556
3.

MACC1-the first decade of a key metastasis molecule from gene discovery to clinical translation.

Radhakrishnan H, Walther W, Zincke F, Kobelt D, Imbastari F, Erdem M, Kortüm B, Dahlmann M, Stein U.

Cancer Metastasis Rev. 2018 Dec;37(4):805-820. doi: 10.1007/s10555-018-9771-8. Review.

PMID:
30607625
4.

Impact of dental cement on the peri-implant biofilm-microbial comparison of two different cements in an in vivo observational study.

Korsch M, Marten SM, Walther W, Vital M, Pieper DH, Dötsch A.

Clin Implant Dent Relat Res. 2018 Oct;20(5):806-813. doi: 10.1111/cid.12650. Epub 2018 Aug 20.

PMID:
30126038
5.

Lateral alveolar ridge augmentation with autogenous block grafts fixed at a distance versus resorbable Poly-D-L-Lactide foil fixed at a distance: A single-blind, randomized, controlled trial.

Bartols A, Kasprzyk S, Walther W, Korsch M.

Clin Oral Implants Res. 2018 Aug;29(8):843-854. doi: 10.1111/clr.13303. Epub 2018 Jun 22.

PMID:
29934956
6.
7.

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.

Holstein M, Mesa-Nuñez C, Miskey C, Almarza E, Poletti V, Schmeer M, Grueso E, Ordóñez Flores JC, Kobelt D, Walther W, Aneja MK, Geiger J, Bonig HB, Izsvák Z, Schleef M, Rudolph C, Mavilio F, Bueren JA, Guenechea G, Ivics Z.

Mol Ther. 2018 Apr 4;26(4):1137-1153. doi: 10.1016/j.ymthe.2018.01.012. Epub 2018 Jan 31.

8.

Targeted suicide gene transfections reveal promising results in nu/nu mice with aggressive neuroblastoma.

Sama S, Woith E, Walther W, Jerz G, Chen W, Hart S, Melzig MF, Weng A.

J Control Release. 2018 Apr 10;275:208-216. doi: 10.1016/j.jconrel.2018.02.031. Epub 2018 Feb 23.

PMID:
29481823
9.

In Colon Epithelia, Clostridium perfringens Enterotoxin Causes Focal Leaks by Targeting Claudins Which are Apically Accessible Due to Tight Junction Derangement.

Eichner M, Augustin C, Fromm A, Piontek A, Walther W, Bücker R, Fromm M, Krause G, Schulzke JD, Günzel D, Piontek J.

J Infect Dis. 2017 Dec 27;217(1):147-157. doi: 10.1093/infdis/jix485.

PMID:
28968861
10.

Mechanisms of Targeting the MDM2-p53-FOXM1 Axis in Well-Differentiated Intestinal Neuroendocrine Tumors.

Briest F, Grass I, Sedding D, Möbs M, Christen F, Benecke J, Fuchs K, Mende S, Kaemmerer D, Sänger J, Kunze A, Geisler C, Freitag H, Lewens F, Worpenberg L, Iwaszkiewicz S, Siegmund B, Walther W, Hummel M, Grabowski P.

Neuroendocrinology. 2018;107(1):1-23. doi: 10.1159/000481506. Epub 2017 Sep 14.

PMID:
28910819
11.

The ability of Reciproc instruments to reach full working length without glide path preparation: a clinical retrospective study.

Bartols A, Robra BP, Walther W.

PeerJ. 2017 Jul 19;5:e3583. doi: 10.7717/peerj.3583. eCollection 2017.

12.

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.

Radhakrishnan H, Ilm K, Walther W, Shirasawa S, Sasazuki T, Daniel PT, Gillissen B, Stein U.

Cancer Lett. 2017 Sep 10;403:231-245. doi: 10.1016/j.canlet.2017.06.020. Epub 2017 Jun 23.

PMID:
28649004
13.

Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1.

Juneja M, Kobelt D, Walther W, Voss C, Smith J, Specker E, Neuenschwander M, Gohlke BO, Dahlmann M, Radetzki S, Preissner R, von Kries JP, Schlag PM, Stein U.

PLoS Biol. 2017 Jun 1;15(6):e2000784. doi: 10.1371/journal.pbio.2000784. eCollection 2017 Jun.

14.

First Evidence for Regeneration of the Periodontium to Mineral Trioxide Aggregate in Human Teeth.

Bartols A, Roussa E, Walther W, Dörfer CE.

J Endod. 2017 May;43(5):715-722. doi: 10.1016/j.joen.2016.12.027. Epub 2017 Mar 18.

PMID:
28325578
15.

Choosing wisely - Preclinical test models in the era of precision medicine.

Klinghammer K, Walther W, Hoffmann J.

Cancer Treat Rev. 2017 Apr;55:36-45. doi: 10.1016/j.ctrv.2017.02.009. Epub 2017 Mar 6. Review.

PMID:
28314175
16.

Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy.

Pahle J, Menzel L, Niesler N, Kobelt D, Aumann J, Rivera M, Walther W.

BMC Cancer. 2017 Feb 13;17(1):129. doi: 10.1186/s12885-017-3123-x.

17.

Pancreatic cancer models for translational research.

Behrens D, Walther W, Fichtner I.

Pharmacol Ther. 2017 May;173:146-158. doi: 10.1016/j.pharmthera.2017.02.013. Epub 2017 Feb 4. Review. No abstract available.

PMID:
28174092
18.

Bacterial Toxins for Oncoleaking Suicidal Cancer Gene Therapy.

Pahle J, Walther W.

Recent Results Cancer Res. 2016;209:95-110. doi: 10.1007/978-3-319-42934-2_7. Review.

PMID:
28101690
19.

Cement-associated peri-implant mucositis. A 1-year follow-up after excess cement removal on the peri-implant tissue of dental implants.

Korsch M, Walther W, Bartols A.

Clin Implant Dent Relat Res. 2017 Jun;19(3):523-529. doi: 10.1111/cid.12470. Epub 2017 Jan 15.

PMID:
28090743
20.

Multiple-file vs. single-file endodontics in dental practice: a study in routine care.

Bartols A, Laux G, Walther W.

PeerJ. 2016 Dec 7;4:e2765. eCollection 2016.

21.

[Professionalization of Legal Dental Experts in Germany: Results of Studies on Structured Focus Groups].

Brauer HU, Walther W, Dick M.

Gesundheitswesen. 2018 Apr;80(4):342-345. doi: 10.1055/s-0042-116588. Epub 2016 Oct 25. German.

PMID:
27780279
22.

Reciproc vs. hand instrumentation in dental practice: a study in routine care.

Bartols A, Reutter CA, Robra BP, Walther W.

PeerJ. 2016 Jun 28;4:e2182. doi: 10.7717/peerj.2182. eCollection 2016.

23.

S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction.

Dahlmann M, Kobelt D, Walther W, Mudduluru G, Stein U.

Cancers (Basel). 2016 Jun 20;8(6). pii: E59. doi: 10.3390/cancers8060059. Review.

24.

Impact of anti-PEG IgM antibodies on the pharmacokinetics of pegylated asparaginase preparations in mice.

Poppenborg SM, Wittmann J, Walther W, Brandenburg G, Krähmer R, Baumgart J, Leenders F.

Eur J Pharm Sci. 2016 Aug 25;91:122-30. doi: 10.1016/j.ejps.2016.06.007. Epub 2016 Jun 10.

PMID:
27292820
25.

Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets.

Mudduluru G, Walther W, Kobelt D, Dahlmann M, Treese C, Assaraf YG, Stein U.

Drug Resist Updat. 2016 May;26:10-27. doi: 10.1016/j.drup.2016.03.002. Epub 2016 Mar 24. Review.

PMID:
27180307
26.

Vectors and strategies for nonviral cancer gene therapy.

Pahle J, Walther W.

Expert Opin Biol Ther. 2016;16(4):443-61. doi: 10.1517/14712598.2016.1134480. Epub 2016 Jan 13. Review.

PMID:
26761200
27.

SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival.

Schmid F, Wang Q, Huska MR, Andrade-Navarro MA, Lemm M, Fichtner I, Dahlmann M, Kobelt D, Walther W, Smith J, Schlag PM, Stein U.

Oncogene. 2016 Nov 17;35(46):5942-5952. doi: 10.1038/onc.2015.451. Epub 2015 Dec 21.

PMID:
26686083
28.

Chemosensitization by diverging modulation by short-term and long-term TNF-α action on ABCB1 expression and NF-κB signaling in colon cancer.

Walther W, Kobelt D, Bauer L, Aumann J, Stein U.

Int J Oncol. 2015 Dec;47(6):2276-85. doi: 10.3892/ijo.2015.3189. Epub 2015 Oct 5.

PMID:
26463665
29.

Prefabricated Versus Customized Abutments: A Retrospective Analysis of Loosening of Cement-Retained Fixed Implant-Supported Reconstructions.

Korsch M, Walther W.

Int J Prosthodont. 2015 Sep-Oct;28(5):522-6. doi: 10.11607/ijp.4307.

PMID:
26340014
30.

[Prevention and Information for Patients Undergoing Periodontal Treatment: Potentials for Improvement from the Patients' Perspective].

Klingenberg A, Walther W, Dörfer CE, Szecsenyi J.

Gesundheitswesen. 2016 May;78(5):319-25. doi: 10.1055/s-0035-1548912. Epub 2015 Jun 18. German.

PMID:
26086539
31.

Oncoleaking: Use of the Pore-Forming Clostridium perfringens Enterotoxin (CPE) for Suicide Gene Therapy.

Pahle J, Aumann J, Kobelt D, Walther W.

Methods Mol Biol. 2015;1317:69-85. doi: 10.1007/978-1-4939-2727-2_5.

PMID:
26072402
32.

Retrospective analysis of loosening of cement-retained vs screw-retained fixed implant-supported reconstructions.

Korsch M, Walther W.

Quintessence Int. 2015 Jul-Aug;46(7):583-9. doi: 10.3290/j.qi.a34077.

PMID:
25918762
33.

Cement-associated signs of inflammation: retrospective analysis of the effect of excess cement on peri-implant tissue.

Korsch M, Robra BP, Walther W.

Int J Prosthodont. 2015 Jan-Feb;28(1):11-8. doi: 10.11607/ijp.4043.

PMID:
25588166
34.

Peri-Implantitis Associated with Type of Cement: A Retrospective Analysis of Different Types of Cement and Their Clinical Correlation to the Peri-Implant Tissue.

Korsch M, Walther W.

Clin Implant Dent Relat Res. 2015 Oct;17 Suppl 2:e434-43. doi: 10.1111/cid.12265. Epub 2014 Sep 2.

PMID:
25180598
35.

Microbial analysis of biofilms on cement surfaces: An investigation in cement-associated peri-implantitis.

Korsch M, Walther W, Marten SM, Obst U.

J Appl Biomater Funct Mater. 2014 Sep 5;12(2):70-80. doi: 10.5301/jabfm.5000206.

PMID:
24980683
36.

Preclinical study on combined chemo- and nonviral gene therapy for sensitization of melanoma using a human TNF-alpha expressing MIDGE DNA vector.

Kobelt D, Aumann J, Schmidt M, Wittig B, Fichtner I, Behrens D, Lemm M, Freundt G, Schlag PM, Walther W.

Mol Oncol. 2014 May;8(3):609-19. doi: 10.1016/j.molonc.2013.12.019. Epub 2014 Jan 18.

37.

Implant counseling and information: questions, predictors, and decision-making of patients before implant therapy.

Korsch M, Robra BP, Walther W.

Clin Oral Implants Res. 2015 Apr;26(4):e47-e50. doi: 10.1111/clr.12329. Epub 2014 Jan 20.

PMID:
24438331
38.

Current status of gene therapy for cancer.

Walther W, Schlag PM.

Curr Opin Oncol. 2013 Nov;25(6):659-64. Review.

PMID:
24100345
39.

A seven-year storage report of good manufacturing practice-grade naked plasmid DNA: stability, topology, and in vitro/in vivo functional analysis.

Walther W, Schmeer M, Kobelt D, Baier R, Harder A, Walhorn V, Anselmetti D, Aumann J, Fichtner I, Schleef M.

Hum Gene Ther Clin Dev. 2013 Dec;24(4):147-53. doi: 10.1089/humc.2013.067. Epub 2013 Oct 24.

PMID:
24067054
40.

Predictors of excess cement and tissue response to fixed implant-supported dentures after cementation.

Korsch M, Robra BP, Walther W.

Clin Implant Dent Relat Res. 2015 Jan;17 Suppl 1:e45-53. doi: 10.1111/cid.12122. Epub 2013 Jul 24.

PMID:
23879821
41.

Cement-associated peri-implantitis: a retrospective clinical observational study of fixed implant-supported restorations using a methacrylate cement.

Korsch M, Obst U, Walther W.

Clin Oral Implants Res. 2014 Jul;25(7):797-802. doi: 10.1111/clr.12173. Epub 2013 Apr 21.

PMID:
23600620
42.

[How dentists experience legal disputes with their patients - a qualitative approach].

Reiß W, Dick M, Walther W, Brauer HU.

Gesundheitswesen. 2013 May;75(5):296-300. doi: 10.1055/s-0033-1334934. Epub 2013 Mar 19. German.

PMID:
23512470
43.

HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: Gene gun is superior to jet injector in inducing CTL responses and protective immunity.

Nguyen-Hoai T, Kobelt D, Hohn O, Vu MD, Schlag PM, Dörken B, Norley S, Lipp M, Walther W, Pezzutto A, Westermann J.

Oncoimmunology. 2012 Dec 1;1(9):1537-1545.

44.

Diversity of patients microflora on orthopaedic and dental implants.

Obst U, Marten SM, Niessner C, Hartwig E, Korsch M, Walther W.

Int J Artif Organs. 2012 Oct;35(10):727-34. doi: 10.5301/ijao.5000144.

PMID:
23138700
45.

Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer.

Galling N, Kobelt D, Aumann J, Schmidt M, Wittig B, Schlag PM, Walther W.

Hum Gene Ther Methods. 2012 Aug;23(4):264-70. doi: 10.1089/hgtb.2012.064. Epub 2012 Aug 27.

PMID:
22924532
46.

Training for legal dental expert witnesses in Germany: an instrument for professional development.

Brauer HU, Walther W, Riesen C, Dick M.

J Dent Educ. 2012 May;76(5):656-60.

47.

In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.

Pichorner A, Sack U, Kobelt D, Kelch I, Arlt F, Smith J, Walther W, Schlag PM, Stein U.

Clin Exp Metastasis. 2012 Aug;29(6):573-83. doi: 10.1007/s10585-012-9472-6. Epub 2012 Apr 7.

PMID:
22484916
48.

Performance of high quality minicircle DNA for in vitro and in vivo gene transfer.

Kobelt D, Schleef M, Schmeer M, Aumann J, Schlag PM, Walther W.

Mol Biotechnol. 2013 Jan;53(1):80-9. doi: 10.1007/s12033-012-9535-6.

PMID:
22467123
49.

Impact of mutant β-catenin on ABCB1 expression and therapy response in colon cancer cells.

Stein U, Fleuter C, Siegel F, Smith J, Kopacek A, Scudiero DA, Hite KM, Schlag PM, Shoemaker RH, Walther W.

Br J Cancer. 2012 Apr 10;106(8):1395-405. doi: 10.1038/bjc.2012.81. Epub 2012 Mar 29.

50.

Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors.

Walther W, Petkov S, Kuvardina ON, Aumann J, Kobelt D, Fichtner I, Lemm M, Piontek J, Blasig IE, Stein U, Schlag PM.

Gene Ther. 2012 May;19(5):494-503. doi: 10.1038/gt.2011.136. Epub 2011 Oct 6.

PMID:
21975465

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