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Restless legs syndrome and health-related quality of life in adults with multiple sclerosis.

Cederberg KLJ, Jeng B, Sasaki JE, Braley TJ, Walters AS, Motl RW.

J Sleep Res. 2019 Jun 3:e12880. doi: 10.1111/jsr.12880. [Epub ahead of print]


Validation of the self-administered version of the international Restless Legs Syndrome study group severity rating scale - The sIRLS.

Sharon D, Allen RP, Martinez-Martin P, Walters AS, Ferini Strambi L, Högl B, Trotti LM, Buchfuhrer M, Swieca J, Bogan RK, Zak R, Hensley JG, Schaefer LA, Marelli S, Zucconi M, Stefani A, Holzknecht E, Olvera V, Meaklim H, Laska I, Becker PM; International RLS Study Group.

Sleep Med. 2019 Feb;54:94-100. doi: 10.1016/j.sleep.2018.10.014. Epub 2018 Oct 29.


Ih contributes to increased motoneuron excitability in restless legs syndrome.

Czesnik D, Howells J, Bartl M, Veiz E, Ketzler R, Kemmet O, Walters AS, Trenkwalder C, Burke D, Paulus W.

J Physiol. 2019 Jan;597(2):599-609. doi: 10.1113/JP275341. Epub 2018 Nov 24.


Deep brain stimulation improves restless legs syndrome in patients with Parkinson disease.

Klepitskaya O, Liu Y, Sharma S, Sillau SH, Tsai J, Walters AS.

Neurology. 2018 Sep 11;91(11):e1013-e1021. doi: 10.1212/WNL.0000000000006162. Epub 2018 Aug 15. Erratum in: Neurology. 2019 Apr 30;92(18):871.


In Reply-Additional Safety Considerations Before Prescribing Opioids to Manage Restless Legs Syndrome.

Silber MH, Becker PM, Buchfuhrer MJ, Earley CJ, Ondo WG, Walters AS, Winkelman JW.

Mayo Clin Proc. 2018 Jul;93(7):955-956. doi: 10.1016/j.mayocp.2018.03.021. No abstract available.


The Appropriate Use of Opioids in the Treatment of Refractory Restless Legs Syndrome.

Silber MH, Becker PM, Buchfuhrer MJ, Earley CJ, Ondo WG, Walters AS, Winkelman JW; Scientific and Medical Advisory Board, Restless Legs Syndrome Foundation.

Mayo Clin Proc. 2018 Jan;93(1):59-67. doi: 10.1016/j.mayocp.2017.11.007.


Prospective study of restless legs syndrome and total and cardiovascular mortality among women.

Li Y, Li Y, Winkelman JW, Walters AS, Han J, Hu FB, Gao X.

Neurology. 2018 Jan 9;90(2):e135-e141. doi: 10.1212/WNL.0000000000004814. Epub 2017 Dec 15.


Reply to: "Periodic Limb Movements During Sleep and White Matter MRI Hyperintensity in Minor Stroke or TIA".

Boulos MI, Muir RT, Gao F, Lim AS, Swartz RH, Black SE, Walters AS, Murray BJ.

Sleep. 2017 May 1;40(5). doi: 10.1093/sleep/zsx060. No abstract available.


The new WASM rules for respiratory-related leg movements lack clinical or polysomnographic validation.

Walters AS.

Sleep Med. 2017 Jun;34:253. doi: 10.1016/j.sleep.2017.03.002. Epub 2017 Mar 14. No abstract available.


Pharmacokinetics of rotigotine transdermal system in adolescents with idiopathic restless legs syndrome (Willis-Ekbom disease).

Elshoff JP, Hudson J, Picchietti DL, Ridel K, Walters AS, Doggett K, Moran K, Oortgiesen M, Ramirez F, Schollmayer E.

Sleep Med. 2017 Apr;32:48-55. doi: 10.1016/j.sleep.2016.04.012. Epub 2016 Jun 8.


Rhythmic movement disorder in childhood: An integrative review.

Gwyther ARM, Walters AS, Hill CM.

Sleep Med Rev. 2017 Oct;35:62-75. doi: 10.1016/j.smrv.2016.08.003. Epub 2016 Aug 26. Review.


Goal orientation and well-being in college athletes: The importance of athletic social connectedness.

Wayment HA, Walters AS.

J Sports Sci. 2017 Nov;35(21):2114-2120. doi: 10.1080/02640414.2016.1257147. Epub 2016 Nov 23.


Validation of the Kohnen Restless Legs Syndrome-Quality of Life instrument.

Kohnen R, Martinez-Martin P, Benes H, Trenkwalder C, Högl B, Dunkl E, Walters AS.

Sleep Med. 2016 Aug;24:10-17. doi: 10.1016/j.sleep.2016.04.019. Epub 2016 Aug 3.


Refining duration and frequency thresholds of restless legs syndrome diagnosis criteria.

Ohayon MM, Bagai K, Roberts LW, Walters AS, Milesi C.

Neurology. 2016 Dec 13;87(24):2546-2553. Epub 2016 Oct 21.


Depth and Distribution of Symptoms in Restless Legs Syndrome/ Willis-Ekbom Disease.

Yeh P, Ondo WG, Picchietti DL, Poceta JS, Allen RP, Davies CR, Wang L, Shi Y, Bagai K, Walters AS.

J Clin Sleep Med. 2016 Dec 15;12(12):1669-1680. doi: 10.5664/jcsm.6356.


Effective Apnea-Hypopnea Index ("Effective AHI"): A New Measure of Effectiveness for Positive Airway Pressure Therapy.

Boyd SB, Upender R, Walters AS, Goodpaster RL, Stanley JJ, Wang L, Chandrasekhar R.

Sleep. 2016 Nov 1;39(11):1961-1972.


Restless Legs Syndrome: Current Concepts about Disease Pathophysiology.

Koo BB, Bagai K, Walters AS.

Tremor Other Hyperkinet Mov (N Y). 2016 Jul 22;6:401. doi: 10.7916/D83J3D2G. eCollection 2016. Review.


Rating of daytime and nighttime symptoms in RLS: validation of the RLS-6 scale of restless legs syndrome/Willis-Ekbom disease.

Kohnen R, Martinez-Martin P, Benes H, Trenkwalder C, Högl B, Dunkl E, Walters AS.

Sleep Med. 2016 Apr;20:116-22. doi: 10.1016/j.sleep.2015.10.014. Epub 2015 Nov 26.


A Pilot Study Assessing the Effects of Pallidal Deep Brain Stimulation on Sleep Quality and Polysomnography in Parkinson's Patients.

Tolleson CM, Bagai K, Walters AS, Davis TL.

Neuromodulation. 2016 Oct;19(7):724-730. doi: 10.1111/ner.12442. Epub 2016 May 17.


Rotigotine's effect on PLM-associated blood pressure elevations in restless legs syndrome: An RCT.

Bauer A, Cassel W, Benes H, Kesper K, Rye D, Sica D, Winkelman JW, Bauer L, Grieger F, Joeres L, Moran K, Schollmayer E, Whitesides J, Carney HC, Walters AS, Oertel W, Trenkwalder C; SP0977 study investigators.

Neurology. 2016 May 10;86(19):1785-93. doi: 10.1212/WNL.0000000000002649. Epub 2016 Apr 13.


Silent Cerebral Small Vessel Disease in Restless Legs Syndrome.

Ferri R, Cosentino FI, Moussouttas M, Lanuzza B, Aricò D, Bagai K, Wang L, McLaughlin B, Walters AS.

Sleep. 2016 Jul 1;39(7):1371-7. doi: 10.5665/sleep.5966.


Identification and Treatment of New Inflammatory Triggers for Complex Regional Pain Syndrome: Small Intestinal Bacterial Overgrowth and Obstructive Sleep Apnea.

Weinstock LB, Myers TL, Walters AS, Schwartz OA, Younger JW, Chopra PJ, Guarino AH.

A A Case Rep. 2016 May 1;6(9):272-6. doi: 10.1213/XAA.0000000000000292.


Association between sleeping difficulty and type 2 diabetes in women.

Li Y, Gao X, Winkelman JW, Cespedes EM, Jackson CL, Walters AS, Schernhammer E, Redline S, Hu FB.

Diabetologia. 2016 Apr;59(4):719-27. doi: 10.1007/s00125-015-3860-9. Epub 2016 Jan 28.


Periodic Limb Movements and White Matter Hyperintensities in First-Ever Minor Stroke or High-Risk Transient Ischemic Attack.

Boulos MI, Murray BJ, Muir RT, Gao F, Szilagyi GM, Huroy M, Kiss A, Walters AS, Black SE, Lim AS, Swartz RH.

Sleep. 2017 Mar 1;40(3). doi: 10.1093/sleep/zsw080.


Restless Legs Syndrome/Willis-Ekbom Disease and Growing Pains in Children and Adolescents.

Simakajornboon N, Dye TJ, Walters AS.

Sleep Med Clin. 2015 Sep;10(3):311-22, xiv. doi: 10.1016/j.jsmc.2015.05.014. Epub 2015 Jul 7. Review.


Dopaminergic Therapy for Restless Legs Syndrome/Willis-Ekbom Disease.

Zak RS, Walters AS.

Sleep Med Clin. 2015 Sep;10(3):279-85, xiii. doi: 10.1016/j.jsmc.2015.05.012. Epub 2015 Jul 14. Review.


Long-Term Effectiveness and Safety of Maxillomandibular Advancement for Treatment of Obstructive Sleep Apnea.

Boyd SB, Walters AS, Waite P, Harding SM, Song Y.

J Clin Sleep Med. 2015 Jul 15;11(7):699-708. doi: 10.5664/jcsm.4838.


REM Sleep Behavioral Events and Dreaming.

Muntean ML, Trenkwalder C, Walters AS, Mollenhauer B, Sixel-Döring F.

J Clin Sleep Med. 2015 Apr 15;11(5):537-41. doi: 10.5664/jcsm.4698.


Consensus clinical practice guidelines for the diagnosis and treatment of restless legs syndrome/Willis-Ekbom disease during pregnancy and lactation.

Picchietti DL, Hensley JG, Bainbridge JL, Lee KA, Manconi M, McGregor JA, Silver RM, Trenkwalder C, Walters AS; International Restless Legs Syndrome Study Group (IRLSSG).

Sleep Med Rev. 2015 Aug;22:64-77. doi: 10.1016/j.smrv.2014.10.009. Epub 2014 Nov 4. Review.


Review of quality of life instruments for the restless legs syndrome/Willis-Ekbom Disease (RLS/WED): critique and recommendations.

Walters AS, Frauscher B, Allen R, Benes H, Chaudhuri KR, Garcia-Borreguero D, Lee HB, Picchietti DL, Trenkwalder C, Martinez-Martin P, Stebbins GT, Schrag A; MDS Committee on Rating Scales.

J Clin Sleep Med. 2014 Dec 15;10(12):1351-7. doi: 10.5664/jcsm.4300. Review.


Review of diagnostic instruments for the restless legs syndrome/Willis-Ekbom Disease (RLS/WED): critique and recommendations.

Walters AS, Frauscher B, Allen R, Benes H, Chaudhuri KR, Garcia-Borreguero D, Lee HB, Picchietti DL, Trenkwalder C, Martinez-Martin P, Stebbins GT, Schrag A; MDS Committee on Rating Scales.

J Clin Sleep Med. 2014 Dec 15;10(12):1343-9. doi: 10.5664/jcsm.4298. Review.


Review of Severity Rating Scales for Restless Legs Syndrome: Critique and Recommendations.

Walters AS, Frauscher B, Allen R, Benes H, Chaudhuri KR, Garcia-Borreguero D, Lee HB, Picchietti DL, Trenkwalder C, Martinez-Martin P, Schrag A, Stebbins G.

Mov Disord Clin Pract. 2014 Sep 30;1(4):317-324. doi: 10.1002/mdc3.12088. eCollection 2014 Dec. Review.


Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance.

Allen RP, Picchietti DL, Garcia-Borreguero D, Ondo WG, Walters AS, Winkelman JW, Zucconi M, Ferri R, Trenkwalder C, Lee HB; International Restless Legs Syndrome Study Group.

Sleep Med. 2014 Aug;15(8):860-73. doi: 10.1016/j.sleep.2014.03.025. Epub 2014 May 17.


A prospective questionnaire study in 100 healthy sleepers: non-bothersome forms of recognizable sleep disorders are still present.

Frauscher B, Mitterling T, Bode A, Ehrmann L, Gabelia D, Biermayr M, Walters AS, Poewe W, Högl B.

J Clin Sleep Med. 2014 Jun 15;10(6):623-9. doi: 10.5664/jcsm.3784.


Restless legs syndrome: a predictor of lower physical function.

Auerbach S, Walters AS.

Neurology. 2014 Apr 8;82(14):1198-9. doi: 10.1212/WNL.0000000000000298. Epub 2014 Mar 5.


Opioids and restless legs syndrome.

Walters AS.

Lancet Neurol. 2013 Dec;12(12):1128-9. doi: 10.1016/S1474-4422(13)70248-5. Epub 2013 Oct 18. No abstract available.


The relationship among restless legs syndrome (Willis-Ekbom Disease), hypertension, cardiovascular disease, and cerebrovascular disease.

Ferini-Strambi L, Walters AS, Sica D.

J Neurol. 2014 Jun;261(6):1051-68. doi: 10.1007/s00415-013-7065-1. Epub 2013 Aug 21. Review.


Comparative effectiveness of maxillomandibular advancement and uvulopalatopharyngoplasty for the treatment of moderate to severe obstructive sleep apnea.

Boyd SB, Walters AS, Song Y, Wang L.

J Oral Maxillofac Surg. 2013 Apr;71(4):743-51. doi: 10.1016/j.joms.2012.10.003. Epub 2012 Dec 6.


Prospective study of restless legs syndrome and coronary heart disease among women.

Li Y, Walters AS, Chiuve SE, Rimm EB, Winkelman JW, Gao X.

Circulation. 2012 Oct 2;126(14):1689-94. doi: 10.1161/CIRCULATIONAHA.112.112698. Epub 2012 Sep 11.


Effectiveness of treatment apnea-hypopnea index: a mathematical estimate of the true apnea-hypopnea index in the home setting.

Boyd SB, Walters AS.

J Oral Maxillofac Surg. 2013 Feb;71(2):351-7. doi: 10.1016/j.joms.2012.05.009. Epub 2012 Jul 6.


Traditional Chinese medicine herbal preparations in restless legs syndrome (RLS) treatment: a review and probable first description of RLS in 1529.

Yan X, Wang WD, Walters AS, Wang Q, Liu YJ, Chu FY.

Sleep Med Rev. 2012 Dec;16(6):509-18. doi: 10.1016/j.smrv.2012.01.003. Epub 2012 Mar 28. Review.


Restless legs syndrome--theoretical roles of inflammatory and immune mechanisms.

Weinstock LB, Walters AS, Paueksakon P.

Sleep Med Rev. 2012 Aug;16(4):341-54. doi: 10.1016/j.smrv.2011.09.003. Epub 2012 Jan 17. Review.


Restless legs syndrome: a comprehensive overview on its epidemiology, risk factors, and treatment.

Yeh P, Walters AS, Tsuang JW.

Sleep Breath. 2012 Dec;16(4):987-1007. doi: 10.1007/s11325-011-0606-x. Epub 2011 Oct 26. Review.


Sleep in children with Williams Syndrome.

Mason TB, Arens R, Sharman J, Bintliff-Janisak B, Schultz B, Walters AS, Cater JR, Kaplan P, Pack AI.

Sleep Med. 2011 Oct;12(9):892-7. doi: 10.1016/j.sleep.2011.05.003. Epub 2011 Sep 21.


A randomized, double-blind, placebo-controlled study to assess the efficacy and tolerability of gabapentin enacarbil in subjects with restless legs syndrome.

Lee DO, Ziman RB, Perkins AT, Poceta JS, Walters AS, Barrett RW; XP053 Study Group.

J Clin Sleep Med. 2011 Jun 15;7(3):282-92. doi: 10.5664/JCSM.1074.


Pediatric restless legs syndrome: analysis of symptom descriptions and drawings.

Picchietti DL, Arbuckle RA, Abetz L, Durmer JS, Ivanenko A, Owens JA, Croenlein J, Allen RP, Walters AS.

J Child Neurol. 2011 Nov;26(11):1365-76. doi: 10.1177/0883073811405852. Epub 2011 Jun 2.


Restless legs syndrome is associated with irritable bowel syndrome and small intestinal bacterial overgrowth.

Weinstock LB, Walters AS.

Sleep Med. 2011 Jun;12(6):610-3. doi: 10.1016/j.sleep.2011.03.007. Epub 2011 May 13.


L-Dopa improves Restless Legs Syndrome and periodic limb movements in sleep but not Attention-Deficit-Hyperactivity Disorder in a double-blind trial in children.

England SJ, Picchietti DL, Couvadelli BV, Fisher BC, Siddiqui F, Wagner ML, Hening WA, Lewin D, Winnie G, Cohen B, Walters AS.

Sleep Med. 2011 May;12(5):471-7. doi: 10.1016/j.sleep.2011.01.008. Epub 2011 Apr 3.

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