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Proteomic changes across a natural temperature gradient in a marine gastropod.

Vasquez MC, Lippert MR, White C, Walter RK, Tomanek L.

Mar Environ Res. 2019 Jun 6. pii: S0141-1136(18)30856-0. doi: 10.1016/j.marenvres.2019.06.002. [Epub ahead of print]


Novel monoclonal antibody-based therapies for acute myeloid leukemia.

Morsink LM, Walter RB.

Best Pract Res Clin Haematol. 2019 Jun;32(2):116-126. doi: 10.1016/j.beha.2019.05.002. Epub 2019 May 9. Review.


Feature identification in time series data sets.

Shaw J, Stastna M, Coutino A, Walter RK, Reinhardt E.

Heliyon. 2019 May 23;5(5):e01708. doi: 10.1016/j.heliyon.2019.e01708. eCollection 2019 May.


Expression Signatures of Cisplatin- and Trametinib-Treated Early-Stage Medaka Melanomas.

Klotz B, Kneitz S, Lu Y, Boswell W, Postlethwait J, Warren W, Walter RB, Schartl M.

G3 (Bethesda). 2019 May 17. pii: g3.400051.2019. doi: 10.1534/g3.119.400051. [Epub ahead of print]


Supplementing standard batterer intervention programmes with individual motivational plans may increase empathic capacity in perpetrators of intimate partner violence.

Walter R.

Evid Based Nurs. 2019 May 15. pii: ebnurs-2018-103039. doi: 10.1136/ebnurs-2018-103039. [Epub ahead of print] No abstract available.


Trends in Clinical Benefits and Costs of Novel Therapeutics in AML: at What Price Does Progress Come?

Vaughn JE, Shankaran V, Walter RB.

Curr Hematol Malig Rep. 2019 Jun;14(3):171-178. doi: 10.1007/s11899-019-00510-2. Review.


Correction: Investigating the Global Dispersal of Chickens in Prehistory Using Ancient Mitochondrial DNA Signatures.

Storey AA, Athens JS, Bryant D, Carson M, Emery K, deFrance S, Higham C, Huynen L, Intoh M, Jones S, Kirch PV, Ladefoged T, McCoy P, Morales-Muñiz A, Quiroz D, Reitz E, Robins J, Walter R, Matisoo-Smith E.

PLoS One. 2019 May 2;14(5):e0216626. doi: 10.1371/journal.pone.0216626. eCollection 2019.


Allogeneic hematopoietic cell transplantation improves outcome of adults with t(6;9) acute myeloid leukemia - results from an international collaborative study.

Kayser S, Hills RK, Luskin MR, Brunner AM, Terré C, Westermann J, Menghrajani K, Shaw C, Baer MR, Elliott MA, Perl AE, Ráčil Z, Mayer J, Zak P, Szotkowski T, de Botton S, Grimwade D, Mayer K, Walter RB, Krämer A, Burnett AK, Ho AD, Platzbecker U, Thiede C, Ehninger G, Stone RM, Röllig C, Tallman MS, Estey EH, Müller-Tidow C, Russell NH, Schlenk RF, Levis MJ.

Haematologica. 2019 Apr 19. pii: haematol.2018.208678. doi: 10.3324/haematol.2018.208678. [Epub ahead of print]


Fluorescent Light Incites a Conserved Immune and Inflammatory Genetic Response within Vertebrate Organs (Danio Rerio, Oryzias Latipes and Mus Musculus).

Boswell M, Lu Y, Boswell W, Savage M, Hildreth K, Salinas R, Walter CA, Walter RB.

Genes (Basel). 2019 Apr 3;10(4). pii: E271. doi: 10.3390/genes10040271.


A real-world, cross-sectional, community survey of symptoms and health-related quality of life of adults with acute myeloid leukemia.

Mamolo CM, Cappelleri JC, Hoang CJ, Kim R, Hadfield A, Middleton C, Rider A, Walter RB.

Future Oncol. 2019 Jun;15(16):1895-1909. doi: 10.2217/fon-2018-0842. Epub 2019 Mar 26.


Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study.

Wei AH, Strickland SA Jr, Hou JZ, Fiedler W, Lin TL, Walter RB, Enjeti A, Tiong IS, Savona M, Lee S, Chyla B, Popovic R, Salem AH, Agarwal S, Xu T, Fakouhi KM, Humerickhouse R, Hong WJ, Hayslip J, Roboz GJ.

J Clin Oncol. 2019 May 20;37(15):1277-1284. doi: 10.1200/JCO.18.01600. Epub 2019 Mar 20.


Diagnostic utility of bronchoscopy in adults with acute myeloid leukemia and other high-grade myeloid neoplasms.

Buckley SA, Mark NM, Othus M, Estey EH, Patel K, Walter RB.

Leuk Lymphoma. 2019 Mar 11:1-4. doi: 10.1080/10428194.2019.1581933. [Epub ahead of print] No abstract available.


Pre-transplant bone marrow monocytic myeloid-derived suppressor cell frequency is not associated with outcome after allogeneic hematopoietic cell transplantation for acute myeloid leukemia in remission.

Godwin CD, Fromm JR, Othus M, Sandmaier BM, Mielcarek MB, Wood BL, Appelbaum FR, Storb R, Walter RB.

Bone Marrow Transplant. 2019 Feb 25. doi: 10.1038/s41409-019-0481-9. [Epub ahead of print] No abstract available.


Use of Mortality as an Endpoint in Noninferiority Trials May Lead to Ethically Problematic Conclusions.

Hersh AM, Walter RJ, Abberegg SK.

J Gen Intern Med. 2019 Apr;34(4):618-623. doi: 10.1007/s11606-018-4813-z. Epub 2019 Feb 12.


Machine learning-based predictors for immune checkpoint inhibitor therapy of non-small-cell lung cancer.

Wiesweg M, Mairinger F, Reis H, Goetz M, Walter RFH, Hager T, Metzenmacher M, Eberhardt WEE, McCutcheon A, Köster J, Stuschke M, Aigner C, Darwiche K, Schmid KW, Rahmann S, Schuler M.

Ann Oncol. 2019 Apr 1;30(4):655-657. doi: 10.1093/annonc/mdz049. No abstract available.


Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro.

Borchert S, Wessolly M, Schmeller J, Mairinger E, Kollmeier J, Hager T, Mairinger T, Herold T, Christoph DC, Walter RFH, Eberhardt WEE, Plönes T, Wohlschlaeger J, Aigner C, Schmid KW, Mairinger FD.

BMC Cancer. 2019 Jan 30;19(1):108. doi: 10.1186/s12885-019-5314-0.


Application of the Transcriptional Disease Signature (TDSs) to Screen Melanoma-Effective Compounds in a Small Fish Model.

Lu Y, Boswell W, Boswell M, Klotz B, Kneitz S, Regneri J, Savage M, Mendoza C, Postlethwait J, Warren WC, Schartl M, Walter RB.

Sci Rep. 2019 Jan 24;9(1):530. doi: 10.1038/s41598-018-36656-x.


In the Eye of the Beholder: A Conjunctival Lesion in a Woman With Acute Myelogenous Leukemia.

McGuffin SA, Bharadwaj R, Gonzalez-Cuyar LF, Schiffer JT, Stacey AW, Walter RB, Duke ER.

Clin Infect Dis. 2019 Jan 18;68(3):525-529. doi: 10.1093/cid/ciy394. No abstract available.


Setting out the frame conditions for feasible use of FFPE derived RNA.

Schmeller J, Wessolly M, Mairinger E, Borchert S, Hager T, Mairinger T, Schmid KW, Wohlschlaeger J, Walter RFH, Mairinger FD.

Pathol Res Pract. 2019 Feb;215(2):381-386. doi: 10.1016/j.prp.2018.12.027. Epub 2018 Dec 28.


Gene expression variation and parental allele inheritance in a Xiphophorus interspecies hybridization model.

Lu Y, Boswell M, Boswell W, Kneitz S, Klotz B, Savage M, Salinas R, Marks R, Regneri J, Postlethwait J, Warren WC, Schartl M, Walter R.

PLoS Genet. 2018 Dec 26;14(12):e1007875. doi: 10.1371/journal.pgen.1007875. eCollection 2018 Dec.


Outpatient induction and consolidation care strategies in acute myeloid leukemia.

Halpern AB, Walter RB, Estey EH.

Curr Opin Hematol. 2019 Mar;26(2):65-70. doi: 10.1097/MOH.0000000000000481.


CLAG-M with dose-escalated mitoxantrone for adults with acute myeloid leukemia.

Halpern AB, Walter RB.

Oncotarget. 2018 Nov 27;9(93):36543-36544. doi: 10.18632/oncotarget.26383. eCollection 2018 Nov 27. No abstract available.


Refining AML outcome prediction.

Hourigan CS, Gale RP, Walter RB.

Leukemia. 2019 Feb;33(2):283-284. doi: 10.1038/s41375-018-0317-4. Epub 2018 Dec 14. No abstract available.


Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Cebola I, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Debette S, Elliott CG, Elwing J, Eyries M, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, MacKenzie Ross RV, Marsolo K, Martin LJ, Moledina S, Montani D, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Sitbon O, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Vonk Noordegraaf A, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Humbert M, Soubrier F, Trégouët DA, Prokopenko I, Kittles R, Gräf S, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR; UK NIHR BioResource Rare Diseases Consortium; UK PAH Cohort Study Consortium; US PAH Biobank Consortium.

Lancet Respir Med. 2019 Mar;7(3):227-238. doi: 10.1016/S2213-2600(18)30409-0. Epub 2018 Dec 5.


Long-term experimental hybridisation results in the evolution of a new sex chromosome in swordtail fish.

Franchini P, Jones JC, Xiong P, Kneitz S, Gompert Z, Warren WC, Walter RB, Meyer A, Schartl M.

Nat Commun. 2018 Dec 3;9(1):5136. doi: 10.1038/s41467-018-07648-2.


Split-Night Polysomnography Overestimates Apnea-Hypopnea Index in High-Risk Professions.

Rouse JK, Shirley SR, Holley AB, Mysliwiec V, Walter RJ.

Mil Med. 2019 May 1;184(5-6):e137-e140. doi: 10.1093/milmed/usy317.


Exendin-4 overcomes cytokine-induced decreases in gap junction coupling via protein kinase A and Epac2 in mouse and human islets.

Farnsworth NL, Walter R, Piscopio RA, Schleicher WE, Benninger RKP.

J Physiol. 2019 Jan;597(2):431-447. doi: 10.1113/JP276106. Epub 2018 Nov 29.


Phase I/II trial of cladribine, high-dose cytarabine, mitoxantrone, and G-CSF with dose-escalated mitoxantrone for relapsed/refractory acute myeloid leukemia and other high-grade myeloid neoplasms.

Halpern AB, Othus M, Huebner EM, Scott BL, Hendrie PC, Percival MM, Becker PS, Smith HA, Oehler VG, Orozco JJ, Cassaday RD, Gardner KM, Chen TL, Buckley SA, Orlowski KF, Anwar A, Estey EH, Walter RB.

Haematologica. 2019 Apr;104(4):e143-e146. doi: 10.3324/haematol.2018.204792. Epub 2018 Nov 8. No abstract available.


Prognostic and therapeutic role of CLEC12A in acute myeloid leukemia.

Morsink LM, Walter RB, Ossenkoppele GJ.

Blood Rev. 2019 Mar;34:26-33. doi: 10.1016/j.blre.2018.10.003. Epub 2018 Nov 1. Review.


Workshop report: Cryopreservation of aquatic biomedical models.

Hagedorn M, Varga Z, Walter RB, Tiersch TR.

Cryobiology. 2019 Feb;86:120-129. doi: 10.1016/j.cryobiol.2018.10.264. Epub 2018 Oct 31.


C3HeB/FeJ Mice mimic many aspects of gene expression and pathobiological features of human hepatocellular carcinoma.

Zavadil JA, Herzig MCS, Hildreth K, Foroushani A, Boswell W, Walter R, Reddick R, White H, Zare H, Walter CA.

Mol Carcinog. 2019 Mar;58(3):309-320. doi: 10.1002/mc.22929. Epub 2018 Nov 25.


Second cycle remission achievement with 7+3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials.

Othus M, Estey EH, Garcia-Manero G, Wood BL, Stirewalt DL, Godwin JE, Weick JK, Anderson JE, Appelbaum FR, Erba HP, Walter RB.

Leukemia. 2019 Feb;33(2):554-558. doi: 10.1038/s41375-018-0274-y. Epub 2018 Oct 12. No abstract available.


Engineering resistance to CD33-targeted immunotherapy in normal hematopoiesis by CRISPR/Cas9-deletion of CD33 exon 2.

Humbert O, Laszlo GS, Sichel S, Ironside C, Haworth KG, Bates OM, Beddoe ME, Carrillo RR, Kiem HP, Walter RB.

Leukemia. 2019 Mar;33(3):762-808. doi: 10.1038/s41375-018-0277-8. Epub 2018 Oct 5. No abstract available.


A comparison of patients with acute myeloid leukemia and high-risk myelodysplastic syndrome treated on versus off study.

Buckley SA, Percival ME, Othus M, Halpern AB, Huebner EM, Becker PS, Shaw C, Shadman M, Walter RB, Estey EH.

Leuk Lymphoma. 2019 Apr;60(4):1023-1029. doi: 10.1080/10428194.2018.1516036. Epub 2018 Oct 2.


Salvage extracorporeal membrane oxygenation in induction-associated acute respiratory distress syndrome in acute leukemia patients: A case series.

Huprikar NA, Peterson MR, DellaVolpe JD, Sams VG, Lantry JH, Walter RJ, Osswald MB, Chung KK, Mason PE.

Int J Artif Organs. 2019 Jan;42(1):49-54. doi: 10.1177/0391398818799160. Epub 2018 Sep 17.


COVA4231, a potent CD3/CD33 bispecific FynomAb with IgG-like pharmacokinetics for the treatment of acute myeloid leukemia.

Klupsch K, Baeriswyl V, Scholz R, Dannenberg J, Santimaria R, Senn D, Kage E, Zumsteg A, Attinger-Toller I, von der Bey U, König-Friedrich S, Dupuy F, Lembke W, Albani C, Wendelspiess S, Dinkel L, Saro D, Hepler RW, Laszlo GS, Gudgeon CJ, Bertschinger J, Brack S, Walter RB.

Leukemia. 2019 Mar;33(3):805-808. doi: 10.1038/s41375-018-0249-z. Epub 2018 Sep 11. No abstract available.


Percutaneous screw fixation for painful non-union of lateral malleolus ankle fractures.

Batten TJ, Scott-Davies C, Butler M, Parsons SW, Walter RP.

Injury. 2018 Oct;49(10):1936-1941. doi: 10.1016/j.injury.2018.08.010. Epub 2018 Aug 16.


Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medaka.

Regneri J, Klotz B, Wilde B, Kottler VA, Hausmann M, Kneitz S, Regensburger M, Maurus K, Götz R, Lu Y, Walter RB, Herpin A, Schartl M.

Pigment Cell Melanoma Res. 2019 Mar;32(2):248-258. doi: 10.1111/pcmr.12729. Epub 2018 Sep 6.


Relationship between CD33 expression, splicing polymorphism, and in vitro cytotoxicity of gemtuzumab ozogamicin and the CD33/CD3 BiTE® AMG 330.

Laszlo GS, Beddoe ME, Godwin CD, Bates OM, Gudgeon CJ, Harrington KH, Walter RB.

Haematologica. 2019 Feb;104(2):e59-e62. doi: 10.3324/haematol.2018.202069. Epub 2018 Aug 16. No abstract available.


Inhibition of MDM2 via Nutlin-3A: A Potential Therapeutic Approach for Pleural Mesotheliomas with MDM2-Induced Inactivation of Wild-Type P53.

Walter RFH, Werner R, Wessolly M, Mairinger E, Borchert S, Schmeller J, Kollmeier J, Mairinger T, Hager T, Bankfalvi A, Christoph DC, Eberhardt WEE, Plönes T, Aigner C, Schmid KW, Wohlschlaeger J, Mairinger FD.

J Oncol. 2018 Jul 17;2018:1986982. doi: 10.1155/2018/1986982. eCollection 2018.


Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis.

Bohnenberger H, Kaderali L, Ströbel P, Yepes D, Plessmann U, Dharia NV, Yao S, Heydt C, Merkelbach-Bruse S, Emmert A, Hoffmann J, Bodemeyer J, Reuter-Jessen K, Lois AM, Dröge LH, Baumeister P, Walz C, Biggemann L, Walter R, Häupl B, Comoglio F, Pan KT, Scheich S, Lenz C, Küffer S, Bremmer F, Kitz J, Sitte M, Beißbarth T, Hinterthaner M, Sebastian M, Lotz J, Schildhaus HU, Wolff H, Danner BC, Brandts C, Büttner R, Canis M, Stegmaier K, Serve H, Urlaub H, Oellerich T.

EMBO Mol Med. 2018 Sep;10(9). pii: e8428. doi: 10.15252/emmm.201708428.


A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML.

Fathi AT, Erba HP, Lancet JE, Stein EM, Ravandi F, Faderl S, Walter RB, Advani AS, DeAngelo DJ, Kovacsovics TJ, Jillella A, Bixby D, Levy MY, O'Meara MM, Ho PA, Voellinger J, Stein AS.

Blood. 2018 Sep 13;132(11):1125-1133. doi: 10.1182/blood-2018-03-841171. Epub 2018 Jul 25.


Impact of region of diagnosis, ethnicity, age, and gender on survival in acute myeloid leukemia (AML).

Acharya UH, Halpern AB, Wu QV, Voutsinas JM, Walter RB, Yun S, Kanaan M, Estey EH.

J Drug Assess. 2018 Jul 10;7(1):51-53. doi: 10.1080/21556660.2018.1492925. eCollection 2018.


Gallium Hydrides and O/N-Donors as Tunable Systems in C-F Bond Activation.

Jaeger AD, Walter R, Ehm C, Lentz D.

Chem Asian J. 2018 Oct 4;13(19):2908-2915. doi: 10.1002/asia.201801030. Epub 2018 Aug 31.


Subsistence practices, past biodiversity, and anthropogenic impacts revealed by New Zealand-wide ancient DNA survey.

Seersholm FV, Cole TL, Grealy A, Rawlence NJ, Greig K, Knapp M, Stat M, Hansen AJ, Easton LJ, Shepherd L, Tennyson AJD, Scofield RP, Walter R, Bunce M.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7771-7776. doi: 10.1073/pnas.1803573115. Epub 2018 Jul 9.


Complex history of dog (Canis familiaris) origins and translocations in the Pacific revealed by ancient mitogenomes.

Greig K, Gosling A, Collins CJ, Boocock J, McDonald K, Addison DJ, Allen MS, David B, Gibbs M, Higham CFW, Liu F, McNiven IJ, O'Connor S, Tsang CH, Walter R, Matisoo-Smith E.

Sci Rep. 2018 Jun 14;8(1):9130. doi: 10.1038/s41598-018-27363-8.


Evaluating measurable residual disease in acute myeloid leukemia.

Ravandi F, Walter RB, Freeman SD.

Blood Adv. 2018 Jun 12;2(11):1356-1366. doi: 10.1182/bloodadvances.2018016378. Review.


Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy.

Mairinger FD, Schmeller J, Borchert S, Wessolly M, Mairinger E, Kollmeier J, Hager T, Mairinger T, Christoph DC, Walter RFH, Eberhardt WEE, Plönes T, Wohlschlaeger J, Jasani B, Schmid KW, Bankfalvi A.

Oncotarget. 2018 Apr 27;9(32):22254-22268. doi: 10.18632/oncotarget.24962. eCollection 2018 Apr 27.


Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancer.

Walter RFH, Rozynek P, Casjens S, Werner R, Mairinger FD, Speel EJM, Zur Hausen A, Meier S, Wohlschlaeger J, Theegarten D, Behrens T, Schmid KW, Brüning T, Johnen G.

PLoS One. 2018 May 31;13(5):e0195716. doi: 10.1371/journal.pone.0195716. eCollection 2018.


Next-generation sequencing for measuring minimal residual disease in AML.

Walter RB, Appelbaum FR.

Nat Rev Clin Oncol. 2018 Aug;15(8):473-474. doi: 10.1038/s41571-018-0040-0. No abstract available.


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