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CX3CR1 as a respiratory syncytial virus receptor in pediatric human lung.

Anderson CS, Chu CY, Wang Q, Mereness JA, Ren Y, Donlon K, Bhattacharya S, Misra RS, Walsh EE, Pryhuber GS, Mariani TJ.

Pediatr Res. 2019 Nov 14. doi: 10.1038/s41390-019-0677-0. [Epub ahead of print]


Microbiome-Transcriptome Interactions Related to Severity of Respiratory Syncytial Virus Infection.

Sonawane AR, Tian L, Chu CY, Qiu X, Wang L, Holden-Wiltse J, Grier A, Gill SR, Caserta MT, Falsey AR, Topham DJ, Walsh EE, Mariani TJ, Weiss ST, Silverman EK, Glass K, Liu YY.

Sci Rep. 2019 Sep 25;9(1):13824. doi: 10.1038/s41598-019-50217-w.


Hypergammaglobulinemia and Impaired Transplacental Transfer of Respiratory Syncytial Virus Antibody in Papua New Guinea.

Atwell JE, Thumar B, Formica MA, Robinson LJ, Walsh EE, King CL, Karron RA.

Pediatr Infect Dis J. 2019 Sep;38(9):e199-e202. doi: 10.1097/INF.0000000000002364.


Mutation of Respiratory Syncytial Virus G Protein's CX3C Motif Attenuates Infection in Cotton Rats and Primary Human Airway Epithelial Cells.

Ha B, Chirkova T, Boukhvalova MS, Sun HY, Walsh EE, Anderson CS, Mariani TJ, Anderson LJ.

Vaccines (Basel). 2019 Jul 19;7(3). pii: E69. doi: 10.3390/vaccines7030069.


Aims, Study Design, and Enrollment Results From the Assessing Predictors of Infant Respiratory Syncytial Virus Effects and Severity Study.

Walsh EE, Mariani TJ, Chu C, Grier A, Gill SR, Qiu X, Wang L, Holden-Wiltse J, Corbett A, Thakar J, Benoodt L, McCall MN, Topham DJ, Falsey AR, Caserta MT.

JMIR Res Protoc. 2019 Jun 6;8(6):e12907. doi: 10.2196/12907.


Delayed Diagnosis of Respiratory Syncytial Virus Infections in Hospitalized Adults: Individual Patient Data, Record Review Analysis and Physician Survey in the United States.

Lee N, Walsh EE, Sander I, Stolper R, Zakar J, Wyffels V, Myers D, Fleischhackl R.

J Infect Dis. 2019 Aug 9;220(6):969-979. doi: 10.1093/infdis/jiz236.


Respiratory syncytial virus-associated illness in adults with advanced chronic obstructive pulmonary disease and/or congestive heart failure.

Falsey AR, Walsh EE, Esser MT, Shoemaker K, Yu L, Griffin MP.

J Med Virol. 2019 Jan;91(1):65-71. doi: 10.1002/jmv.25285. Epub 2018 Sep 24.


T-Cell Responses in Adults During Natural Respiratory Syncytial Virus Infection.

Roumanes D, Falsey AR, Quataert S, Secor-Socha S, Lee FE, Yang H, Bandyopadhyay S, Holden-Wiltse J, Topham DJ, Walsh EE.

J Infect Dis. 2018 Jul 2;218(3):418-428. doi: 10.1093/infdis/jiy016.


The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.

Mazur NI, Higgins D, Nunes MC, Melero JA, Langedijk AC, Horsley N, Buchholz UJ, Openshaw PJ, McLellan JS, Englund JA, Mejias A, Karron RA, Simões EA, Knezevic I, Ramilo O, Piedra PA, Chu HY, Falsey AR, Nair H, Kragten-Tabatabaie L, Greenough A, Baraldi E, Papadopoulos NG, Vekemans J, Polack FP, Powell M, Satav A, Walsh EE, Stein RT, Graham BS, Bont LJ; Respiratory Syncytial Virus Network (ReSViNET) Foundation.

Lancet Infect Dis. 2018 Oct;18(10):e295-e311. doi: 10.1016/S1473-3099(18)30292-5. Epub 2018 Jun 18. Review. Erratum in: Lancet Infect Dis. 2018 Jul 25;:.


To Test or Not To Test?: The Value of Toxicology in a Delayed Overdose Death.

Walsh EE, Shoff EN, Elizabeth Zaney M, Hime GW, Garavan F, Boland DM.

J Forensic Sci. 2019 Jan;64(1):314-317. doi: 10.1111/1556-4029.13822. Epub 2018 May 17.


Virus-Specific Antibody, Viral Load, and Disease Severity in Respiratory Syncytial Virus Infection.

Walsh EE, Wang L, Falsey AR, Qiu X, Corbett A, Holden-Wiltse J, Mariani TJ, Topham DJ, Caserta MT.

J Infect Dis. 2018 Jun 20;218(2):208-217. doi: 10.1093/infdis/jiy106.


Importation, Mitigation, and Genomic Epidemiology of Candida auris at a Large Teaching Hospital.

Lesho EP, Bronstein MZ, McGann P, Stam J, Kwak Y, Maybank R, McNamara J, Callahan M, Campbell J, Hinkle MK, Walsh EE.

Infect Control Hosp Epidemiol. 2018 Jan;39(1):53-57. doi: 10.1017/ice.2017.231. Epub 2017 Dec 6.


Association of Dynamic Changes in the CD4 T-Cell Transcriptome With Disease Severity During Primary Respiratory Syncytial Virus Infection in Young Infants.

Mariani TJ, Qiu X, Chu C, Wang L, Thakar J, Holden-Wiltse J, Corbett A, Topham DJ, Falsey AR, Caserta MT, Walsh EE.

J Infect Dis. 2017 Nov 15;216(8):1027-1037. doi: 10.1093/infdis/jix400.


Identifying Gaps in Respiratory Syncytial Virus Disease Epidemiology in the United States Prior to the Introduction of Vaccines.

Kim L, Rha B, Abramson JS, Anderson LJ, Byington CL, Chen GL, DeVincenzo J, Edwards KM, Englund JA, Falsey AR, Griffin MR, Karron RA, Martin KG, Meissner HC, Munoz FM, Pavia AT, Piedra PA, Schaffner W, Simões EAF, Singleton R, Talbot HK, Walsh EE, Zucker JR, Gerber SI.

Clin Infect Dis. 2017 Sep 15;65(6):1020-1025. doi: 10.1093/cid/cix432.


Can Analysis of Routine Viral Testing Provide Accurate Estimates of Respiratory Syncytial Virus Disease Burden in Adults?

Datta S, Walsh EE, Peterson DR, Falsey AR.

J Infect Dis. 2017 Jun 1;215(11):1706-1710. doi: 10.1093/infdis/jix196.


Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness.

Bhattacharya S, Rosenberg AF, Peterson DR, Grzesik K, Baran AM, Ashton JM, Gill SR, Corbett AM, Holden-Wiltse J, Topham DJ, Walsh EE, Mariani TJ, Falsey AR.

Sci Rep. 2017 Jul 26;7(1):6548. doi: 10.1038/s41598-017-06738-3.


Empirically Determined Vascular Smooth Muscle Cell Mechano-Adaptation Law.

Steucke KE, Win Z, Stemler TR, Walsh EE, Hall JL, Alford PW.

J Biomech Eng. 2017 Jul 1;139(7). doi: 10.1115/1.4036454.


Respiratory Syncytial Virus Infection: An Illness for All Ages.

Walsh EE.

Clin Chest Med. 2017 Mar;38(1):29-36. doi: 10.1016/j.ccm.2016.11.010. Epub 2016 Dec 27. Review.


Compassionate use experience with high-titer respiratory syncytical virus (RSV) immunoglobulin in RSV-infected immunocompromised persons.

Falsey AR, Koval C, DeVincenzo JP, Walsh EE.

Transpl Infect Dis. 2017 Apr;19(2). doi: 10.1111/tid.12657. Epub 2017 Mar 6.


Development of a Global Respiratory Severity Score for Respiratory Syncytial Virus Infection in Infants.

Caserta MT, Qiu X, Tesini B, Wang L, Murphy A, Corbett A, Topham DJ, Falsey AR, Holden-Wiltse J, Walsh EE.

J Infect Dis. 2017 Mar 1;215(5):750-756. doi: 10.1093/infdis/jiw624. Erratum in: J Infect Dis. 2017 Sep 15;216(6):786.


The Healthy Infant Nasal Transcriptome: A Benchmark Study.

Chu CY, Qiu X, Wang L, Bhattacharya S, Lofthus G, Corbett A, Holden-Wiltse J, Grier A, Tesini B, Gill SR, Falsey AR, Caserta MT, Walsh EE, Mariani TJ.

Sci Rep. 2016 Sep 23;6:33994. doi: 10.1038/srep33994.


Development of Electrochemiluminescent Serology Assays to Measure the Humoral Response to Antigens of Respiratory Syncytial Virus.

Maifeld SV, Ro B, Mok H, Chu M, Yu L, Yamagata R, Leonardson T, Chio V, Parhy B, Park S, Carlson M, Machhi S, Ulbrandt N, Falsey AR, Walsh EE, Wang CK, Esser MT, Zuo F.

PLoS One. 2016 Apr 12;11(4):e0153019. doi: 10.1371/journal.pone.0153019. eCollection 2016.


Provider Decisions to Treat Respiratory Illnesses with Antibiotics: Insights from a Randomized Controlled Trial.

Branche AR, Walsh EE, Jadhav N, Karmally R, Baran A, Peterson DR, Falsey AR.

PLoS One. 2016 Apr 4;11(4):e0152986. doi: 10.1371/journal.pone.0152986. eCollection 2016.


Improved immunogenicity of high-dose influenza vaccine compared to standard-dose influenza vaccine in adult oncology patients younger than 65 years receiving chemotherapy: A pilot randomized clinical trial.

Jamshed S, Walsh EE, Dimitroff LJ, Santelli JS, Falsey AR.

Vaccine. 2016 Jan 27;34(5):630-635. doi: 10.1016/j.vaccine.2015.12.037. Epub 2015 Dec 22.


Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures.

Johnson SM, McNally BA, Ioannidis I, Flano E, Teng MN, Oomens AG, Walsh EE, Peeples ME.

PLoS Pathog. 2015 Dec 11;11(12):e1005318. doi: 10.1371/journal.ppat.1005318. eCollection 2015 Dec.


Should clinical case definitions of influenza in hospitalized older adults include fever?

Falsey AR, Baran A, Walsh EE.

Influenza Other Respir Viruses. 2015 Aug;9 Suppl 1:23-9. doi: 10.1111/irv.12316.


Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.

Halliley JL, Tipton CM, Liesveld J, Rosenberg AF, Darce J, Gregoretti IV, Popova L, Kaminiski D, Fucile CF, Albizua I, Kyu S, Chiang KY, Bradley KT, Burack R, Slifka M, Hammarlund E, Wu H, Zhao L, Walsh EE, Falsey AR, Randall TD, Cheung WC, Sanz I, Lee FE.

Immunity. 2015 Jul 21;43(1):132-45. doi: 10.1016/j.immuni.2015.06.016. Epub 2015 Jul 14.


Effect of Preexisting Serum and Mucosal Antibody on Experimental Respiratory Syncytial Virus (RSV) Challenge and Infection of Adults.

Bagga B, Cehelsky JE, Vaishnaw A, Wilkinson T, Meyers R, Harrison LM, Roddam PL, Walsh EE, DeVincenzo JP.

J Infect Dis. 2015 Dec 1;212(11):1719-25. doi: 10.1093/infdis/jiv281. Epub 2015 May 14.


Serum Procalcitonin Measurement and Viral Testing to Guide Antibiotic Use for Respiratory Infections in Hospitalized Adults: A Randomized Controlled Trial.

Branche AR, Walsh EE, Vargas R, Hulbert B, Formica MA, Baran A, Peterson DR, Falsey AR.

J Infect Dis. 2015 Dec 1;212(11):1692-700. doi: 10.1093/infdis/jiv252. Epub 2015 Apr 24.


Challenges and opportunities in developing respiratory syncytial virus therapeutics.

Simões EA, DeVincenzo JP, Boeckh M, Bont L, Crowe JE Jr, Griffiths P, Hayden FG, Hodinka RL, Smyth RL, Spencer K, Thirstrup S, Walsh EE, Whitley RJ.

J Infect Dis. 2015 Mar 15;211 Suppl 1:S1-S20. doi: 10.1093/infdis/jiu828.


Superiority of transcriptional profiling over procalcitonin for distinguishing bacterial from viral lower respiratory tract infections in hospitalized adults.

Suarez NM, Bunsow E, Falsey AR, Walsh EE, Mejias A, Ramilo O.

J Infect Dis. 2015 Jul 15;212(2):213-22. doi: 10.1093/infdis/jiv047. Epub 2015 Jan 29. Erratum in: J Infect Dis. 2015 Dec 15;212(12):2023.


Detection of respiratory viruses in sputum from adults by use of automated multiplex PCR.

Branche AR, Walsh EE, Formica MA, Falsey AR.

J Clin Microbiol. 2014 Oct;52(10):3590-6. doi: 10.1128/JCM.01523-14. Epub 2014 Jul 23.


Respiratory syncytial virus transplacental antibody transfer and kinetics in mother-infant pairs in Bangladesh.

Chu HY, Steinhoff MC, Magaret A, Zaman K, Roy E, Langdon G, Formica MA, Walsh EE, Englund JA.

J Infect Dis. 2014 Nov 15;210(10):1582-9. doi: 10.1093/infdis/jiu316. Epub 2014 Jun 5.


Respiratory syncytial virus in hematopoietic cell transplant recipients: factors determining progression to lower respiratory tract disease.

Kim YJ, Guthrie KA, Waghmare A, Walsh EE, Falsey AR, Kuypers J, Cent A, Englund JA, Boeckh M.

J Infect Dis. 2014 Apr 15;209(8):1195-204. doi: 10.1093/infdis/jit832. Epub 2013 Dec 23.


Subunit and virus-like particle vaccine approaches for respiratory syncytial virus.

Morrison TG, Walsh EE.

Curr Top Microbiol Immunol. 2013;372:285-306. doi: 10.1007/978-3-642-38919-1_14. Review.


Reply to Musher et al.

Falsey AR, Walsh EE.

J Infect Dis. 2014 Feb 15;209(4):633-5. doi: 10.1093/infdis/jit580. Epub 2013 Nov 11. No abstract available.


Clinical impact of human coronaviruses 229E and OC43 infection in diverse adult populations.

Walsh EE, Shin JH, Falsey AR.

J Infect Dis. 2013 Nov 15;208(10):1634-42. doi: 10.1093/infdis/jit393. Epub 2013 Aug 6.


Bacterial complications of respiratory tract viral illness: a comprehensive evaluation.

Falsey AR, Becker KL, Swinburne AJ, Nylen ES, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Baran A, Walsh EE.

J Infect Dis. 2013 Aug 1;208(3):432-41. doi: 10.1093/infdis/jit190. Epub 2013 May 9.


Risk factors for respiratory syncytial virus illness among patients with chronic obstructive pulmonary disease.

Mehta J, Walsh EE, Mahadevia PJ, Falsey AR.

COPD. 2013 Jun;10(3):293-9. doi: 10.3109/15412555.2012.744741. Epub 2013 Mar 28.


Viral shedding and immune responses to respiratory syncytial virus infection in older adults.

Walsh EE, Peterson DR, Kalkanoglu AE, Lee FE, Falsey AR.

J Infect Dis. 2013 May 1;207(9):1424-32. doi: 10.1093/infdis/jit038. Epub 2013 Feb 4.


Can serum procalcitonin levels help interpret indeterminate chest radiographs in patients hospitalized with acute respiratory illness?

Walsh EE, Swinburne AJ, Becker KL, Nylen ES, Snider RH, Baran A, Peterson DR, Falsey AR.

J Hosp Med. 2013 Feb;8(2):61-7. doi: 10.1002/jhm.1984. Epub 2012 Oct 19.


Factors associated with symptomatic rhinovirus infection in patients with COPD.

Gandhi A, Walsh EE, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Baran A, Falsey AR.

J Clin Virol. 2012 Dec;55(4):343-7. doi: 10.1016/j.jcv.2012.08.020. Epub 2012 Sep 19.


Simple method for combining sputum and nasal samples for virus detection by reverse transcriptase PCR.

Falsey AR, Formica MA, Walsh EE.

J Clin Microbiol. 2012 Aug;50(8):2835. doi: 10.1128/JCM.01473-12. Epub 2012 Jun 12. No abstract available.


Utility of serum procalcitonin values in patients with acute exacerbations of chronic obstructive pulmonary disease: a cautionary note.

Falsey AR, Becker KL, Swinburne AJ, Nylen ES, Snider RH, Formica MA, Hennessey PA, Criddle MM, Peterson DR, Walsh EE.

Int J Chron Obstruct Pulmon Dis. 2012;7:127-35. doi: 10.2147/COPD.S29149. Epub 2012 Feb 23.


Respiratory syncytial virus infection in adult populations.

Walsh EE, Falsey AR.

Infect Disord Drug Targets. 2012 Apr;12(2):98-102. Review.


Statins and influenza: can we move forward?

Walsh EE.

J Infect Dis. 2012 Jan 1;205(1):1-3. doi: 10.1093/infdis/jir693. Epub 2011 Dec 13. No abstract available.


Yield of sputum for viral detection by reverse transcriptase PCR in adults hospitalized with respiratory illness.

Falsey AR, Formica MA, Walsh EE.

J Clin Microbiol. 2012 Jan;50(1):21-4. doi: 10.1128/JCM.05841-11. Epub 2011 Nov 16.


Respiratory syncytial virus infection in adults.

Walsh EE.

Semin Respir Crit Care Med. 2011 Aug;32(4):423-32. doi: 10.1055/s-0031-1283282. Epub 2011 Aug 19. Review.


The effect of steroid use in hospitalized adults with respiratory syncytial virus-related illness.

Lee FE, Walsh EE, Falsey AR.

Chest. 2011 Nov;140(5):1155-1161. doi: 10.1378/chest.11-0047. Epub 2011 May 12.


Circulating human antibody-secreting cells during vaccinations and respiratory viral infections are characterized by high specificity and lack of bystander effect.

Lee FE, Halliley JL, Walsh EE, Moscatiello AP, Kmush BL, Falsey AR, Randall TD, Kaminiski DA, Miller RK, Sanz I.

J Immunol. 2011 May 1;186(9):5514-21. doi: 10.4049/jimmunol.1002932. Epub 2011 Mar 25.

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