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Items: 1 to 50 of 438


Investigating musculoskeletal health and wellbeing; a cohort study protocol.

Millar B, McWilliams DF, Abhishek A, Akin-Akinyosoye K, Auer DP, Chapman V, Doherty M, Ferguson E, Gladman JRF, Greenhaff P, Stocks J, Valdes AM, Walsh DA.

BMC Musculoskelet Disord. 2020 Mar 21;21(1):182. doi: 10.1186/s12891-020-03195-4.


Neurophysiological alterations in the nucleus reuniens of a mouse model of Alzheimer's disease.

Walsh DA, Brown JT, Randall AD.

Neurobiol Aging. 2020 Apr;88:1-10. doi: 10.1016/j.neurobiolaging.2019.12.006. Epub 2019 Dec 12.


Giant virus diversity and host interactions through global metagenomics.

Schulz F, Roux S, Paez-Espino D, Jungbluth S, Walsh DA, Denef VJ, McMahon KD, Konstantinidis KT, Eloe-Fadrosh EA, Kyrpides NC, Woyke T.

Nature. 2020 Feb;578(7795):432-436. doi: 10.1038/s41586-020-1957-x. Epub 2020 Jan 22.


Secular changes in the progression of clinical markers and patient-reported outcomes in early rheumatoid arthritis.

Carpenter L, Nikiphorou E, Kiely PDW, Walsh DA, Young A, Norton S.

Rheumatology (Oxford). 2020 Jan 3. pii: kez635. doi: 10.1093/rheumatology/kez635. [Epub ahead of print]


Disease activity flares and pain flares in an early rheumatoid arthritis inception cohort; characteristics, antecedents and sequelae.

McWilliams DF, Rahman S, James RJE, Ferguson E, Kiely PDW, Young A, Walsh DA.

BMC Rheumatol. 2019 Nov 18;3:49. doi: 10.1186/s41927-019-0100-9. eCollection 2019.


Baseline self-report 'central mechanisms' trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort.

Akin-Akinyosoye K, Sarmanova A, Fernandes GS, Frowd N, Swaithes L, Stocks J, Valdes A, McWilliams DF, Zhang W, Doherty M, Ferguson E, Walsh DA.

Osteoarthritis Cartilage. 2020 Feb;28(2):173-181. doi: 10.1016/j.joca.2019.11.004. Epub 2019 Dec 10.


Remission vs low disease activity: function, quality of life and structural outcomes in the Early Rheumatoid Arthritis Study and Network.

Nikiphorou E, Norton SJ, Carpenter L, Walsh DA, Creamer P, Dixey J, Young A, Kiely PDW.

Rheumatology (Oxford). 2019 Oct 3. pii: kez461. doi: 10.1093/rheumatology/kez461. [Epub ahead of print]


Diversity and biogeography of SAR11 bacteria from the Arctic Ocean.

Kraemer S, Ramachandran A, Colatriano D, Lovejoy C, Walsh DA.

ISME J. 2020 Jan;14(1):79-90. doi: 10.1038/s41396-019-0499-4. Epub 2019 Sep 9.


Peripheral brain-derived neurotrophic factor contributes to chronic osteoarthritis joint pain.

Gowler PRW, Li L, Woodhams SG, Bennett AJ, Suzuki R, Walsh DA, Chapman V.

Pain. 2020 Jan;161(1):61-73. doi: 10.1097/j.pain.0000000000001694.


Host-Guest Hybrid Redox Materials Self-Assembled from Polyoxometalates and Single-Walled Carbon Nanotubes.

Jordan JW, Lowe GA, McSweeney RL, Stoppiello CT, Lodge RW, Skowron ST, Biskupek J, Rance GA, Kaiser U, Walsh DA, Newton GN, Khlobystov AN.

Adv Mater. 2019 Oct;31(41):e1904182. doi: 10.1002/adma.201904182. Epub 2019 Aug 26.


The NSERC Canadian Lake Pulse Network: A national assessment of lake health providing science for water management in a changing climate.

Huot Y, Brown CA, Potvin G, Antoniades D, Baulch HM, Beisner BE, Bélanger S, Brazeau S, Cabana H, Cardille JA, Del Giorgio PA, Gregory-Eaves I, Fortin MJ, Lang AS, Laurion I, Maranger R, Prairie YT, Rusak JA, Segura PA, Siron R, Smol JP, Vinebrooke RD, Walsh DA.

Sci Total Environ. 2019 Dec 10;695:133668. doi: 10.1016/j.scitotenv.2019.133668. Epub 2019 Aug 4.


A tale of two TrkA inhibitor trials: same target, divergent results.

Walsh DA, Neogi T.

Osteoarthritis Cartilage. 2019 Nov;27(11):1575-1577. doi: 10.1016/j.joca.2019.07.013. Epub 2019 Jul 26. No abstract available.


CGRP and Painful Pathologies Other than Headache.

Walsh DA, McWilliams DF.

Handb Exp Pharmacol. 2019;255:141-167. doi: 10.1007/164_2019_242.


Efficient Electrocatalytic CO2 Reduction Driven by Ionic Liquid Buffer-Like Solutions.

Gonçalves WDG, Zanatta M, Simon NM, Rutzen LM, Walsh DA, Dupont J.

ChemSusChem. 2019 Sep 20;12(18):4170-4175. doi: 10.1002/cssc.201901076. Epub 2019 Jul 25.


The Functional Requirement for CD69 in Establishment of Resident Memory CD8+ T Cells Varies with Tissue Location.

Walsh DA, Borges da Silva H, Beura LK, Peng C, Hamilton SE, Masopust D, Jameson SC.

J Immunol. 2019 Aug 15;203(4):946-955. doi: 10.4049/jimmunol.1900052. Epub 2019 Jun 26.


Is incident rheumatoid arthritis interstitial lung disease associated with methotrexate treatment? Results from a multivariate analysis in the ERAS and ERAN inception cohorts.

Kiely P, Busby AD, Nikiphorou E, Sullivan K, Walsh DA, Creamer P, Dixey J, Young A.

BMJ Open. 2019 May 5;9(5):e028466. doi: 10.1136/bmjopen-2018-028466.


Quantitative sensory testing and predicting outcomes for musculoskeletal pain, disability, and negative affect: a systematic review and meta-analysis.

Georgopoulos V, Akin-Akinyosoye K, Zhang W, McWilliams DF, Hendrick P, Walsh DA.

Pain. 2019 Sep;160(9):1920-1932. doi: 10.1097/j.pain.0000000000001590.


Trajectories of pain predict disabilities affecting daily living in arthritis.

James RJE, Walsh DA, Ferguson E.

Br J Health Psychol. 2019 Sep;24(3):485-496. doi: 10.1111/bjhp.12364. Epub 2019 Apr 7.


Annual nitrification dynamics in a seasonally ice-covered lake.

Massé S, Botrel M, Walsh DA, Maranger R.

PLoS One. 2019 Mar 20;14(3):e0213748. doi: 10.1371/journal.pone.0213748. eCollection 2019.


Interpretation of DAS28 and its components in the assessment of inflammatory and non-inflammatory aspects of rheumatoid arthritis.

McWilliams DF, Kiely PDW, Young A, Joharatnam N, Wilson D, Walsh DA.

BMC Rheumatol. 2018 Mar 23;2:8. doi: 10.1186/s41927-018-0016-9. eCollection 2018.


The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis.

Ashraf S, Radhi M, Gowler P, Burston JJ, Gandhi RD, Thorn GJ, Piccinini AM, Walsh DA, Chapman V, de Moor CH.

Sci Rep. 2019 Mar 18;9(1):4696. doi: 10.1038/s41598-019-41140-1.


The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation.

Burston JJ, Valdes AM, Woodhams SG, Mapp PI, Stocks J, Watson DJG, Gowler PRW, Xu L, Sagar DR, Fernandes G, Frowd N, Marshall L, Zhang W, Doherty M, Walsh DA, Chapman V.

Pain. 2019 Mar;160(3):658-669. doi: 10.1097/j.pain.0000000000001445.


Analgesic effects of the cathepsin K inhibitor L-006235 in the monosodium iodoacetate model of osteoarthritis pain.

Nwosu LN, Gowler PRW, Burston JJ, Rizoska B, Tunblad K, Lindström E, Grabowska U, Li L, McWilliams DF, Walsh DA, Chapman V.

Pain Rep. 2018 Oct 5;3(6):e685. doi: 10.1097/PR9.0000000000000685. eCollection 2018 Nov.


Progress and Challenges in Ocean Metaproteomics and Proposed Best Practices for Data Sharing.

Saito MA, Bertrand EM, Duffy ME, Gaylord DA, Held NA, Hervey WJ 4th, Hettich RL, Jagtap PD, Janech MG, Kinkade DB, Leary DH, McIlvin MR, Moore EK, Morris RM, Neely BA, Nunn BL, Saunders JK, Shepherd AI, Symmonds NI, Walsh DA.

J Proteome Res. 2019 Apr 5;18(4):1461-1476. doi: 10.1021/acs.jproteome.8b00761. Epub 2019 Mar 12.


Associations of Symptomatic Knee Osteoarthritis With Histopathologic Features in Subchondral Bone.

Aso K, Shahtaheri SM, Hill R, Wilson D, McWilliams DF, Walsh DA.

Arthritis Rheumatol. 2019 Jun;71(6):916-924. doi: 10.1002/art.40820. Epub 2019 May 2.


Discrete Trajectories of Resolving and Persistent Pain in People With Rheumatoid Arthritis Despite Undergoing Treatment for Inflammation: Results From Three UK Cohorts.

McWilliams DF, Dawson O, Young A, Kiely PDW, Ferguson E, Walsh DA.

J Pain. 2019 Jun;20(6):716-727. doi: 10.1016/j.jpain.2019.01.001. Epub 2019 Jan 15.


Author Correction: A compendium of geochemical information from the Saanich Inlet water column.

Torres-Beltrán M, Hawley AK, Capelle D, Zaikova E, Walsh DA, Mueller A, Scofield M, Payne C, Pakhomova L, Kheirandish S, Finke J, Bhatia M, Shevchuk O, Gies EA, Fairley D, Michiels C, Suttle CA, Whitney F, Crowe SA, Tortell PD, Hallam SJ.

Sci Data. 2019 Jan 15;6(1):1. doi: 10.1038/s41597-018-0005-2.


Molecular expression patterns in the synovium and their association with advanced symptomatic knee osteoarthritis.

Wyatt LA, Nwosu LN, Wilson D, Hill R, Spendlove I, Bennett AJ, Scammell BE, Walsh DA.

Osteoarthritis Cartilage. 2019 Apr;27(4):667-675. doi: 10.1016/j.joca.2018.12.012. Epub 2018 Dec 28.


Thresholds of ultrasound synovial abnormalities for knee osteoarthritis - a cross sectional study in the general population.

Sarmanova A, Hall M, Fernandes GS, Valdes AM, Walsh DA, Doherty M, Zhang W.

Osteoarthritis Cartilage. 2019 Mar;27(3):435-443. doi: 10.1016/j.joca.2018.09.018. Epub 2018 Nov 16.


Validation of methods for converting the original Disease Activity Score (DAS) to the DAS28.

Carpenter L, Norton S, Nikiphorou E, Kiely P, Walsh DA, Dixey J, Young A.

Rheumatol Int. 2018 Dec;38(12):2297-2305. doi: 10.1007/s00296-018-4184-0. Epub 2018 Oct 27.


Genomic evidence for the degradation of terrestrial organic matter by pelagic Arctic Ocean Chloroflexi bacteria.

Colatriano D, Tran PQ, Guéguen C, Williams WJ, Lovejoy C, Walsh DA.

Commun Biol. 2018 Jul 5;1:90. doi: 10.1038/s42003-018-0086-7. eCollection 2018.


Neuropathic-like knee pain and associated risk factors: a cross-sectional study in a UK community sample.

Fernandes GS, Valdes AM, Walsh DA, Zhang W, Doherty M.

Arthritis Res Ther. 2018 Sep 27;20(1):215. doi: 10.1186/s13075-018-1717-6.


The relative efficacy of topical non-steroidal anti-inflammatory drugs and capsaicin in osteoarthritis: a network meta-analysis of randomised controlled trials.

Persson MSM, Stocks J, Walsh DA, Doherty M, Zhang W.

Osteoarthritis Cartilage. 2018 Dec;26(12):1575-1582. doi: 10.1016/j.joca.2018.08.008. Epub 2018 Aug 30. Review.


Contribution of central and peripheral risk factors to prevalence, incidence and progression of knee pain: a community-based cohort study.

Sarmanova A, Fernandes GS, Richardson H, Valdes AM, Walsh DA, Zhang W, Doherty M.

Osteoarthritis Cartilage. 2018 Nov;26(11):1461-1473. doi: 10.1016/j.joca.2018.07.013. Epub 2018 Aug 10.


Effects of carrageenan induced synovitis on joint damage and pain in a rat model of knee osteoarthritis.

Ashraf S, Mapp PI, Shahtaheri SM, Walsh DA.

Osteoarthritis Cartilage. 2018 Oct;26(10):1369-1378. doi: 10.1016/j.joca.2018.07.001. Epub 2018 Jul 19.


The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.

Borges da Silva H, Beura LK, Wang H, Hanse EA, Gore R, Scott MC, Walsh DA, Block KE, Fonseca R, Yan Y, Hippen KL, Blazar BR, Masopust D, Kelekar A, Vulchanova L, Hogquist KA, Jameson SC.

Nature. 2018 Jul;559(7713):264-268. doi: 10.1038/s41586-018-0282-0. Epub 2018 Jul 4.


Bidirectional association between disturbed sleep and neuropathic pain symptoms: a prospective cohort study in post-total joint replacement participants.

Stocks J, Tang NK, Walsh DA, Warner SC, Harvey HL, Jenkins W, Abhishek A, Doherty M, Valdes AM.

J Pain Res. 2018 Jun 6;11:1087-1093. doi: 10.2147/JPR.S149830. eCollection 2018.


Microbial life under ice: Metagenome diversity and in situ activity of Verrucomicrobia in seasonally ice-covered Lakes.

Tran P, Ramachandran A, Khawasik O, Beisner BE, Rautio M, Huot Y, Walsh DA.

Environ Microbiol. 2018 Jul;20(7):2568-2584. doi: 10.1111/1462-2920.14283.


General and disease-specific pain trajectories as predictors of social and political outcomes in arthritis and cancer.

James RJE, Walsh DA, Ferguson E.

BMC Med. 2018 Apr 9;16(1):51. doi: 10.1186/s12916-018-1031-9.


Clinical- and cost-effectiveness of the STAR care pathway compared to usual care for patients with chronic pain after total knee replacement: study protocol for a UK randomised controlled trial.

Wylde V, Bertram W, Beswick AD, Blom AW, Bruce J, Burston A, Dennis J, Garfield K, Howells N, Lane A, McCabe C, Moore AJ, Noble S, Peters TJ, Price A, Sanderson E, Toms AD, Walsh DA, White S, Gooberman-Hill R.

Trials. 2018 Feb 21;19(1):132. doi: 10.1186/s13063-018-2516-8.


Traits associated with central pain augmentation in the Knee Pain In the Community (KPIC) cohort.

Akin-Akinyosoye K, Frowd N, Marshall L, Stocks J, Fernandes GS, Valdes A, McWilliams DF, Zhang W, Doherty M, Ferguson E, Walsh DA.

Pain. 2018 Jun;159(6):1035-1044. doi: 10.1097/j.pain.0000000000001183.


Home-based pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): a feasibility randomized controlled trial.

das Nair R, Mhizha-Murira JR, Anderson P, Carpenter H, Clarke S, Groves S, Leighton P, Scammell BE, Topcu G, Walsh DA, Lincoln NB.

Clin Rehabil. 2018 Jun;32(6):777-789. doi: 10.1177/0269215518755426. Epub 2018 Feb 9.


Association between ultrasound-detected synovitis and knee pain: a population-based case-control study with both cross-sectional and follow-up data.

Sarmanova A, Hall M, Fernandes GS, Bhattacharya A, Valdes AM, Walsh DA, Doherty M, Zhang W.

Arthritis Res Ther. 2017 Dec 19;19(1):281. doi: 10.1186/s13075-017-1486-7.


Author Correction: Demonstration of sub-luminal propagation of single-cycle terahertz pulses for particle acceleration.

Walsh DA, Lake DS, Snedden EW, Cliffe MJ, Graham DM, Jamison SP.

Nat Commun. 2017 Nov 23;8(1):1837. doi: 10.1038/s41467-017-01653-7.


Correction to "Electroanalysis of Neutral Precursors in Protic Ionic Liquids and Synthesis of High-Ionicity Ionic Liquids".

Goodwin SE, Smith DE, Gibson JS, Jones RG, Walsh DA.

Langmuir. 2017 Dec 5;33(48):13902. doi: 10.1021/acs.langmuir.7b03820. Epub 2017 Nov 20. No abstract available.


A compendium of geochemical information from the Saanich Inlet water column.

Torres-Beltrán M, Hawley AK, Capelle D, Zaikova E, Walsh DA, Mueller A, Scofield M, Payne C, Pakhomova L, Kheirandish S, Finke J, Bhatia M, Shevchuk O, Gies EA, Fairley D, Michiels C, Suttle CA, Whitney F, Crowe SA, Tortell PD, Hallam SJ.

Sci Data. 2017 Oct 31;4:170159. doi: 10.1038/sdata.2017.159. Erratum in: Sci Data. 2019 Jan 15;6(1):1.


A compendium of multi-omic sequence information from the Saanich Inlet water column.

Hawley AK, Torres-Beltrán M, Zaikova E, Walsh DA, Mueller A, Scofield M, Kheirandish S, Payne C, Pakhomova L, Bhatia M, Shevchuk O, Gies EA, Fairley D, Malfatti SA, Norbeck AD, Brewer HM, Pasa-Tolic L, Del Rio TG, Suttle CA, Tringe S, Hallam SJ.

Sci Data. 2017 Oct 31;4:170160. doi: 10.1038/sdata.2017.160.


Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica.

Williams NH, Jenkins A, Goulden N, Hoare Z, Hughes DA, Wood E, Foster NE, Walsh DA, Carnes D, Sparkes V, Hay EM, Isaacs J, Konstantinou K, Morrissey D, Karppinen J, Genevay S, Wilkinson C.

Health Technol Assess. 2017 Oct;21(60):1-180. doi: 10.3310/hta21600.


Pain mechanisms in rheumatoid arthritis.

McWilliams DF, Walsh DA.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 107(5):94-101. Epub 2017 Sep 29. Review.


Bedroom media: One risk factor for development.

Gentile DA, Berch ON, Choo H, Khoo A, Walsh DA.

Dev Psychol. 2017 Dec;53(12):2340-2355. doi: 10.1037/dev0000399. Epub 2017 Sep 25.


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