Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 38

1.

Collagen VI Contains Multiple Host Defense Peptides with Potent In Vivo Activity.

Abdillahi SM, Maaß T, Kasetty G, Strömstedt AA, Baumgarten M, Tati R, Nordin SL, Walse B, Wagener R, Schmidtchen A, Mörgelin M.

J Immunol. 2018 Jun 20. pii: ji1700602. doi: 10.4049/jimmunol.1700602. [Epub ahead of print]

PMID:
29925677
2.

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 May 22;9(1):2071. doi: 10.1038/s41467-018-04198-5.

3.

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 Mar 16;9(1):1107. doi: 10.1038/s41467-018-03441-3. Erratum in: Nat Commun. 2018 May 22;9(1):2071.

4.

Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2).

Anderson LC, Håkansson M, Walse B, Nilsson CL.

J Am Soc Mass Spectrom. 2017 Sep;28(9):1796-1804. doi: 10.1007/s13361-017-1705-0. Epub 2017 Jul 5.

5.

Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain Proteins.

Nilsson LM, Green LC, Muralidharan SV, Demir D, Welin M, Bhadury J, Logan DT, Walse B, Nilsson JA.

Cancer Res. 2016 Apr 15;76(8):2376-83. doi: 10.1158/0008-5472.CAN-15-2721. Epub 2016 Mar 3.

6.

De Novo Fragment Design for Drug Discovery and Chemical Biology.

Rodrigues T, Reker D, Welin M, Caldera M, Brunner C, Gabernet G, Schneider P, Walse B, Schneider G.

Angew Chem Int Ed Engl. 2015 Dec 7;54(50):15079-83. doi: 10.1002/anie.201508055. Epub 2015 Oct 21.

PMID:
26486226
7.

Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules.

von Schantz L, Håkansson M, Logan DT, Walse B, Osterlin J, Nordberg-Karlsson E, Ohlin M.

Glycobiology. 2012 Jul;22(7):948-61. doi: 10.1093/glycob/cws063. Epub 2012 Mar 20.

PMID:
22434778
8.

Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP.

Humble MS, Cassimjee KE, Håkansson M, Kimbung YR, Walse B, Abedi V, Federsel HJ, Berglund P, Logan DT.

FEBS J. 2012 Mar;279(5):779-92. doi: 10.1111/j.1742-4658.2012.08468.x. Epub 2012 Jan 23.

9.

Antimicrobial activity of peptides derived from human ß-amyloid precursor protein.

Papareddy P, Mörgelin M, Walse B, Schmidtchen A, Malmsten M.

J Pept Sci. 2012 Mar;18(3):183-91. doi: 10.1002/psc.1439. Epub 2012 Jan 16.

PMID:
22249992
10.

The C-terminal sequence of several human serine proteases encodes host defense functions.

Kasetty G, Papareddy P, Kalle M, Rydengård V, Walse B, Svensson B, Mörgelin M, Malmsten M, Schmidtchen A.

J Innate Immun. 2011;3(5):471-82. doi: 10.1159/000327016. Epub 2011 May 11.

11.

Proteolysis of human thrombin generates novel host defense peptides.

Papareddy P, Rydengård V, Pasupuleti M, Walse B, Mörgelin M, Chalupka A, Malmsten M, Schmidtchen A.

PLoS Pathog. 2010 Apr 22;6(4):e1000857. doi: 10.1371/journal.ppat.1000857.

12.

Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution.

Svensson SL, Pasupuleti M, Walse B, Malmsten M, Mörgelin M, Sjögren C, Olin AI, Collin M, Schmidtchen A, Palmer R, Egesten A.

J Biol Chem. 2010 May 21;285(21):16105-15. doi: 10.1074/jbc.M109.081232. Epub 2010 Mar 22.

13.

Inhibition of human DHODH by 4-hydroxycoumarins, fenamic acids, and N-(alkylcarbonyl)anthranilic acids identified by structure-guided fragment selection.

Fritzson I, Svensson B, Al-Karadaghi S, Walse B, Wellmar U, Nilsson UJ, da Graça Thrige D, Jönsson S.

ChemMedChem. 2010 Apr 6;5(4):608-17. doi: 10.1002/cmdc.200900454.

PMID:
20183850
14.

Directed evolution of chemotaxis inhibitory protein of Staphylococcus aureus generates biologically functional variants with reduced interaction with human antibodies.

Gustafsson E, Rosén A, Barchan K, van Kessel KP, Haraldsson K, Lindman S, Forsberg C, Ljung L, Bryder K, Walse B, Haas PJ, van Strijp JA, Furebring C.

Protein Eng Des Sel. 2010 Feb;23(2):91-101. doi: 10.1093/protein/gzp062. Epub 2009 Dec 3.

PMID:
19959567
15.

Identification of conformational epitopes for human IgG on Chemotaxis inhibitory protein of Staphylococcus aureus.

Gustafsson E, Haas PJ, Walse B, Hijnen M, Furebring C, Ohlin M, van Strijp JA, van Kessel KP.

BMC Immunol. 2009 Mar 11;10:13. doi: 10.1186/1471-2172-10-13.

16.

Rational design of antimicrobial C3a analogues with enhanced effects against Staphylococci using an integrated structure and function-based approach.

Pasupuleti M, Walse B, Svensson B, Malmsten M, Schmidtchen A.

Biochemistry. 2008 Sep 2;47(35):9057-70. doi: 10.1021/bi800991e. Epub 2008 Aug 9.

PMID:
18690701
17.

The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites.

Walse B, Dufe VT, Svensson B, Fritzson I, Dahlberg L, Khairoullina A, Wellmar U, Al-Karadaghi S.

Biochemistry. 2008 Aug 26;47(34):8929-36. doi: 10.1021/bi8003318. Epub 2008 Aug 2.

PMID:
18672895
18.

Development of interleukin-1 receptor antagonist mutants with enhanced antagonistic activity in vitro and improved therapeutic efficacy in collagen-induced arthritis.

Dahlén E, Barchan K, Herrlander D, Höjman P, Karlsson M, Ljung L, Andersson M, Bäckman E, Hager AC, Walse B, Joosten L, van den Berg W.

J Immunotoxicol. 2008 Apr;5(2):189-99. doi: 10.1080/15476910802131477.

PMID:
18569390
19.

Cutting edge: Evidence of direct TCR alpha-chain interaction with superantigen.

Pumphrey N, Vuidepot A, Jakobsen B, Forsberg G, Walse B, Lindkvist-Petersson K.

J Immunol. 2007 Sep 1;179(5):2700-4.

20.

Antimicrobial peptides derived from growth factors.

Malmsten M, Davoudi M, Walse B, Rydengård V, Pasupuleti M, Mörgelin M, Schmidtchen A.

Growth Factors. 2007 Feb;25(1):60-70.

PMID:
17454151
21.

Discovery of selective small-molecule CD80 inhibitors.

Uvebrant K, da Graça Thrige D, Rosén A, Akesson M, Berg H, Walse B, Björk P.

J Biomol Screen. 2007 Jun;12(4):464-72. Epub 2007 Apr 13.

PMID:
17435172
22.

Preservation of antimicrobial properties of complement peptide C3a, from invertebrates to humans.

Pasupuleti M, Walse B, Nordahl EA, Mörgelin M, Malmsten M, Schmidtchen A.

J Biol Chem. 2007 Jan 26;282(4):2520-8. Epub 2006 Nov 27.

23.

Crystal structure of a soluble CD28-Fab complex.

Evans EJ, Esnouf RM, Manso-Sancho R, Gilbert RJ, James JR, Yu C, Fennelly JA, Vowles C, Hanke T, Walse B, Hünig T, Sørensen P, Stuart DI, Davis SJ.

Nat Immunol. 2005 Mar;6(3):271-9. Epub 2005 Feb 6.

PMID:
15696168
24.

Identification of protein-protein interfaces implicated in CD80-CD28 costimulatory signaling.

Sørensen P, Kussmann M, Rosén A, Bennett KL, Thrige Dda G, Uvebrant K, Walse B, Roepstorff P, Björk P.

J Immunol. 2004 Jun 1;172(11):6803-9.

25.

Interplay between superantigens and immunoreceptors.

Petersson K, Forsberg G, Walse B.

Scand J Immunol. 2004 Apr;59(4):345-55. Review.

26.

Identification of the antigenic epitopes in staphylococcal enterotoxins A and E and design of a superantigen for human cancer therapy.

Erlandsson E, Andersson K, Cavallin A, Nilsson A, Larsson-Lorek U, Niss U, Sjöberg A, Wallén-Ohman M, Antonsson P, Walse B, Forsberg G.

J Mol Biol. 2003 Nov 7;333(5):893-905.

PMID:
14583188
27.

Staphylococcal enterotoxin H induces V alpha-specific expansion of T cells.

Petersson K, Pettersson H, Skartved NJ, Walse B, Forsberg G.

J Immunol. 2003 Apr 15;170(8):4148-54.

28.

Crystal structure of a SEA variant in complex with MHC class II reveals the ability of SEA to crosslink MHC molecules.

Petersson K, Thunnissen M, Forsberg G, Walse B.

Structure. 2002 Dec;10(12):1619-26.

29.

The interaction properties of costimulatory molecules revisited.

Collins AV, Brodie DW, Gilbert RJ, Iaboni A, Manso-Sancho R, Walse B, Stuart DI, van der Merwe PA, Davis SJ.

Immunity. 2002 Aug;17(2):201-10.

30.

Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence.

Petersson K, Håkansson M, Nilsson H, Forsberg G, Svensson LA, Liljas A, Walse B.

EMBO J. 2001 Jul 2;20(13):3306-12.

31.

Binding of peptides in solution by the Escherichia coli chaperone PapD as revealed using an inhibition ELISA and NMR spectroscopy.

Karlsson KF, Walse B, Drakenberg T, Roy S, Bergquist KE, Pinkner JS, Hultgren SJ, Kihlberg J.

Bioorg Med Chem. 1998 Nov;6(11):2085-101.

PMID:
9881099
32.
33.

Transferred nuclear Overhauser effect spectroscopy study of a peptide from the PapG pilus subunit bound by the Escherichia coli PapD chaperone.

Walse B, Kihlberg J, Karlsson KF, Nilsson M, Wahlund KG, Pinkner JS, Hultgren SJ, Drakenberg T.

FEBS Lett. 1997 Jul 21;412(1):115-20.

34.
35.

Structure of a cyclic peptide with a catalytic triad, determined by computer simulation and NMR spectroscopy.

Walse B, Ullner M, Lindbladh C, Bülow L, Drakenberg T, Teleman O.

J Comput Aided Mol Des. 1996 Feb;10(1):11-22.

PMID:
8786411
36.

Structural features of a polypeptide carrier promoting secretion of a beta-lactamase fusion protein in yeast.

Jämsä E, Holkeri H, Vihinen H, Wikström M, Simonen M, Walse B, Kalkkinen N, Paakkola J, Makarow M.

Yeast. 1995 Nov;11(14):1381-91.

PMID:
8585321
37.

Glycosylated peptide hormones: pharmacological properties and conformational studies of analogues of [1-desamino,8-D-arginine]vasopressin.

Kihlberg J, Ahman J, Walse B, Drakenberg T, Nilsson A, Söderberg-ahlm C, Bengtsson B, Olsson H.

J Med Chem. 1995 Jan 6;38(1):161-9.

PMID:
7837227
38.

Supplemental Content

Support Center