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Items: 1 to 50 of 60

1.

Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling.

Chandran S, Suggs JA, Wang BJ, Han A, Bhide S, Cryderman DE, Moore SA, Bernstein SI, Wallrath LL, Melkani GC.

Hum Mol Genet. 2019 Feb 1;28(3):351-371. doi: 10.1093/hmg/ddy332.

PMID:
30239736
2.

Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan.

Bhide S, Trujillo AS, O'Connor MT, Young GH, Cryderman DE, Chandran S, Nikravesh M, Wallrath LL, Melkani GC.

Aging Cell. 2018 Jun;17(3):e12747. doi: 10.1111/acel.12747. Epub 2018 Mar 25.

3.

Cross talk between the cytoplasm and nucleus during development and disease.

Wallrath LL, Bohnekamp J, Magin TM.

Curr Opin Genet Dev. 2016 Apr;37:129-136. doi: 10.1016/j.gde.2016.03.007. Epub 2016 Apr 23. Review.

PMID:
27110666
4.

Using Drosophila for Studies of Intermediate Filaments.

Bohnekamp J, Cryderman DE, Thiemann DA, Magin TM, Wallrath LL.

Methods Enzymol. 2016;568:707-26. doi: 10.1016/bs.mie.2015.08.028. Epub 2015 Oct 24.

PMID:
26795490
5.

Myopathic lamin mutations cause reductive stress and activate the nrf2/keap-1 pathway.

Dialynas G, Shrestha OK, Ponce JM, Zwerger M, Thiemann DA, Young GH, Moore SA, Yu L, Lammerding J, Wallrath LL.

PLoS Genet. 2015 May 21;11(5):e1005231. doi: 10.1371/journal.pgen.1005231. eCollection 2015 May.

6.

A Drosophila Model of Epidermolysis Bullosa Simplex.

Bohnekamp J, Cryderman DE, Paululat A, Baccam GC, Wallrath LL, Magin TM.

J Invest Dermatol. 2015 Aug;135(8):2031-2039. doi: 10.1038/jid.2015.129. Epub 2015 Apr 1.

7.

Human heterochromatin protein 1α promotes nucleosome associations that drive chromatin condensation.

Azzaz AM, Vitalini MW, Thomas AS, Price JP, Blacketer MJ, Cryderman DE, Zirbel LN, Woodcock CL, Elcock AH, Wallrath LL, Shogren-Knaak MA.

J Biol Chem. 2014 Mar 7;289(10):6850-61. doi: 10.1074/jbc.M113.512137. Epub 2014 Jan 10.

8.

Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.

Fagan RL, Cryderman DE, Kopelovich L, Wallrath LL, Brenner C.

J Biol Chem. 2013 Aug 16;288(33):23858-67. doi: 10.1074/jbc.M113.480517. Epub 2013 Jul 9.

9.

The Drosophila nuclear lamina protein otefin is required for germline stem cell survival.

Barton LJ, Pinto BS, Wallrath LL, Geyer PK.

Dev Cell. 2013 Jun 24;25(6):645-54. doi: 10.1016/j.devcel.2013.05.023.

10.

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling.

Zwerger M, Jaalouk DE, Lombardi ML, Isermann P, Mauermann M, Dialynas G, Herrmann H, Wallrath LL, Lammerding J.

Hum Mol Genet. 2013 Jun 15;22(12):2335-49. doi: 10.1093/hmg/ddt079. Epub 2013 Feb 19.

11.

Enforcing silencing: dynamic HP1 complexes in Neurospora.

Wallrath LL, Elgin SC.

Nat Struct Mol Biol. 2012 May 3;19(5):465-7. doi: 10.1038/nsmb.2291.

PMID:
22551706
12.

LMNA variants cause cytoplasmic distribution of nuclear pore proteins in Drosophila and human muscle.

Dialynas G, Flannery KM, Zirbel LN, Nagy PL, Mathews KD, Moore SA, Wallrath LL.

Hum Mol Genet. 2012 Apr 1;21(7):1544-56. doi: 10.1093/hmg/ddr592. Epub 2011 Dec 20.

13.

Heterochromatin protein 1a is required for an open chromatin structure.

Cryderman DE, Vitalini MW, Wallrath LL.

Transcription. 2011 Mar;2(2):95-99.

14.

Nuclear organization: taking a position on gene expression.

Geyer PK, Vitalini MW, Wallrath LL.

Curr Opin Cell Biol. 2011 Jun;23(3):354-9. doi: 10.1016/j.ceb.2011.03.002. Epub 2011 Mar 28. Review.

15.

Chromatin and chromosomes.

Gilbert DM, Wallrath LL.

Mol Biol Cell. 2011 Mar 15;22(6):717. doi: 10.1091/mbc.E10-12-0990. No abstract available.

16.

The role of Drosophila Lamin C in muscle function and gene expression.

Dialynas G, Speese S, Budnik V, Geyer PK, Wallrath LL.

Development. 2010 Sep;137(18):3067-77. doi: 10.1242/dev.048231. Epub 2010 Aug 11.

17.

A comparative study of Drosophila and human A-type lamins.

Schulze SR, Curio-Penny B, Speese S, Dialynas G, Cryderman DE, McDonough CW, Nalbant D, Petersen M, Budnik V, Geyer PK, Wallrath LL.

PLoS One. 2009 Oct 26;4(10):e7564. doi: 10.1371/journal.pone.0007564.

18.

Domains of heterochromatin protein 1 required for Drosophila melanogaster heterochromatin spreading.

Hines KA, Cryderman DE, Flannery KM, Yang H, Vitalini MW, Hazelrigg T, Mizzen CA, Wallrath LL.

Genetics. 2009 Aug;182(4):967-77. doi: 10.1534/genetics.109.105338. Epub 2009 Jun 1.

19.

Stimulating conversations between HP1a and histone demethylase dKDM4A.

Wallrath LL, Elgin SC.

Mol Cell. 2008 Dec 5;32(5):601-2. doi: 10.1016/j.molcel.2008.11.015.

20.

Editorial. Epigenetics of development and human disease.

Wallrath LL, Nagy PL, Geyer PK.

Mutat Res. 2008 Dec 1;647(1-2):1-2. doi: 10.1016/j.mrfmmm.2008.10.008. Epub 2008 Oct 25. No abstract available.

21.

Linking Heterochromatin Protein 1 (HP1) to cancer progression.

Dialynas GK, Vitalini MW, Wallrath LL.

Mutat Res. 2008 Dec 1;647(1-2):13-20. doi: 10.1016/j.mrfmmm.2008.09.007. Epub 2008 Sep 24. Review.

22.

Heterochromatin: not just for silencing anymore: report of the Eighth International Conference on Drosophila Heterochromatin.

Geyer PK, Wallrath LL.

Fly (Austin). 2007 Jul-Aug;1(4):251-6. Epub 2007 Jul 3. No abstract available.

PMID:
18820453
23.

Tissue-specific defects are caused by loss of the Drosophila MAN1 LEM domain protein.

Pinto BS, Wilmington SR, Hornick EE, Wallrath LL, Geyer PK.

Genetics. 2008 Sep;180(1):133-45. doi: 10.1534/genetics.108.091371. Epub 2008 Aug 24.

24.

Preferential dimethylation of histone H4 lysine 20 by Suv4-20.

Yang H, Pesavento JJ, Starnes TW, Cryderman DE, Wallrath LL, Kelleher NL, Mizzen CA.

J Biol Chem. 2008 May 2;283(18):12085-92. doi: 10.1074/jbc.M707974200. Epub 2008 Feb 21.

25.

Connections between epigenetic gene silencing and human disease.

Moss TJ, Wallrath LL.

Mutat Res. 2007 May 1;618(1-2):163-74. Epub 2007 Jan 21. Review.

26.

Gene regulation by chromatin structure: paradigms established in Drosophila melanogaster.

Schulze SR, Wallrath LL.

Annu Rev Entomol. 2007;52:171-92. Review.

PMID:
16881818
27.

TFIIIC boxes in the genome.

Wallrath LL, Geyer PK.

Cell. 2006 Jun 2;125(5):829-31. Review.

28.

A requirement for dimerization of HP1Hsalpha in suppression of breast cancer invasion.

Norwood LE, Moss TJ, Margaryan NV, Cook SL, Wright L, Seftor EA, Hendrix MJ, Kirschmann DA, Wallrath LL.

J Biol Chem. 2006 Jul 7;281(27):18668-76. Epub 2006 Apr 28.

29.

Molecular genetic analysis of the nested Drosophila melanogaster lamin C gene.

Schulze SR, Curio-Penny B, Li Y, Imani RA, Rydberg L, Geyer PK, Wallrath LL.

Genetics. 2005 Sep;171(1):185-96. Epub 2005 Jun 18.

30.

Role of Drosophila HP1 in euchromatic gene expression.

Cryderman DE, Grade SK, Li Y, Fanti L, Pimpinelli S, Wallrath LL.

Dev Dyn. 2005 Mar;232(3):767-74.

31.

Conserved properties of HP1(Hsalpha).

Norwood LE, Grade SK, Cryderman DE, Hines KA, Furiasse N, Toro R, Li Y, Dhasarathy A, Kladde MP, Hendrix MJ, Kirschmann DA, Wallrath LL.

Gene. 2004 Jul 7;336(1):37-46.

PMID:
15225874
32.

Mechanisms of HP1-mediated gene silencing in Drosophila.

Danzer JR, Wallrath LL.

Development. 2004 Aug;131(15):3571-80. Epub 2004 Jun 23.

33.

Immunofluorescent staining of polytene chromosomes: exploiting genetic tools.

Stephens GE, Craig CA, Li Y, Wallrath LL, Elgin SC.

Methods Enzymol. 2004;376:372-93. Review. No abstract available.

PMID:
14975319
34.

Heterochromatin, position effects, and the genetic dissection of chromatin.

Eissenberg JC, Wallrath LL.

Prog Nucleic Acid Res Mol Biol. 2003;74:275-99. Review. No abstract available.

PMID:
14510079
35.

Effects of tethering HP1 to euchromatic regions of the Drosophila genome.

Li Y, Danzer JR, Alvarez P, Belmont AS, Wallrath LL.

Development. 2003 May;130(9):1817-24.

36.

Does heterochromatin protein 1 always follow code?

Li Y, Kirschmann DA, Wallrath LL.

Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4:16462-9. Epub 2002 Jul 31. Review.

37.

Reaching for new heitz.

Henikoff S, Eissenberg JC, Hilliker AJ, Schmidt ER, Wallrath LL.

Genetica. 2000;109(1-2):7-8. No abstract available.

PMID:
11293797
38.

Drosophila telomeric transgenes provide insights on mechanisms of gene silencing.

Wallrath LL.

Genetica. 2000;109(1-2):25-33. Review.

PMID:
11293791
39.

Down-regulation of HP1Hsalpha expression is associated with the metastatic phenotype in breast cancer.

Kirschmann DA, Lininger RA, Gardner LM, Seftor EA, Odero VA, Ainsztein AM, Earnshaw WC, Wallrath LL, Hendrix MJ.

Cancer Res. 2000 Jul 1;60(13):3359-63.

40.

The fourth chromosome of Drosophila melanogaster: interspersed euchromatic and heterochromatic domains.

Sun FL, Cuaycong MH, Craig CA, Wallrath LL, Locke J, Elgin SC.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5340-5.

41.

Heterochromatic silencing of Drosophila heat shock genes acts at the level of promoter potentiation.

Cryderman DE, Tang H, Bell C, Gilmour DS, Wallrath LL.

Nucleic Acids Res. 1999 Aug 15;27(16):3364-70.

42.

Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles.

Cryderman DE, Morris EJ, Biessmann H, Elgin SC, Wallrath LL.

EMBO J. 1999 Jul 1;18(13):3724-35.

43.

Analysis of Drosophila chromatin structure in vivo.

Cartwright IL, Cryderman DE, Gilmour DS, Pile LA, Wallrath LL, Weber JA, Elgin SC.

Methods Enzymol. 1999;304:462-96. No abstract available.

PMID:
10372377
44.

Characterization of sequences associated with position-effect variegation at pericentric sites in Drosophila heterochromatin.

Cryderman DE, Cuaycong MH, Elgin SC, Wallrath LL.

Chromosoma. 1998 Nov;107(5):277-85.

PMID:
9880760
45.

Unfolding the mysteries of heterochromatin.

Wallrath LL.

Curr Opin Genet Dev. 1998 Apr;8(2):147-53. Review.

PMID:
9610404
46.
47.

The role of a positioned nucleosome at the Drosophila melanogaster hsp26 promoter.

Lu Q, Wallrath LL, Elgin SC.

EMBO J. 1995 Oct 2;14(19):4738-46.

48.
49.

Insensitivity of the present hsp26 chromatin structure to a TATA box mutation in Drosophila.

Lu Q, Wallrath LL, Emanuel PA, Elgin SC, Gilmour DS.

J Biol Chem. 1994 Jun 3;269(22):15906-11.

50.

Nucleosome positioning and gene regulation.

Lu Q, Wallrath LL, Elgin SC.

J Cell Biochem. 1994 May;55(1):83-92. Review.

PMID:
8083303

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