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Items: 1 to 50 of 455

1.

Incidence of spontaneous arrhythmias in freely moving healthy untreated Sprague-Dawley rats.

Pereira PJS, Pugsley MK, Troncy E, Tan W, Pouliot M, Harper C, Prefontaine A, Easter A, Wallis R, Miraucourt L, Huang H, Accardi MV, Boulay E, Maghezzi MS, Authier S.

J Pharmacol Toxicol Methods. 2019 May 31:106589. doi: 10.1016/j.vascn.2019.106589. [Epub ahead of print]

2.

TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB - a study protocol.

Rachow A, Ivanova O, Wallis R, Charalambous S, Jani I, Bhatt N, Kampmann B, Sutherland J, Ntinginya NE, Evans D, Lönnroth K, Niemann S, Schaible UE, Geldmacher C, Sanne I, Hoelscher M, Churchyard G.

BMC Pulm Med. 2019 Jan 7;19(1):4. doi: 10.1186/s12890-018-0777-3.

3.

Publisher Correction: A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis.

Imperial MZ, Nahid P, Phillips PPJ, Davies GR, Fielding K, Hanna D, Hermann D, Wallis RS, Johnson JL, Lienhardt C, Savic RM.

Nat Med. 2019 Jan;25(1):190. doi: 10.1038/s41591-018-0294-1.

PMID:
30429542
4.

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis.

Imperial MZ, Nahid P, Phillips PPJ, Davies GR, Fielding K, Hanna D, Hermann D, Wallis RS, Johnson JL, Lienhardt C, Savic RM.

Nat Med. 2018 Nov;24(11):1708-1715. doi: 10.1038/s41591-018-0224-2. Epub 2018 Nov 5. Erratum in: Nat Med. 2019 Jan;25(1):190.

5.

Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis.

Turapov O, Forti F, Kadhim B, Ghisotti D, Sassine J, Straatman-Iwanowska A, Bottrill AR, Moynihan PJ, Wallis R, Barthe P, Cohen-Gonsaud M, Ajuh P, Vollmer W, Mukamolova GV.

Cell Rep. 2018 Oct 2;25(1):57-67.e5. doi: 10.1016/j.celrep.2018.09.004.

6.

Sonication versus Tissue Sampling for Diagnosis of Prosthetic Joint and Other Orthopedic Device-Related Infections.

Dudareva M, Barrett L, Figtree M, Scarborough M, Watanabe M, Newnham R, Wallis R, Oakley S, Kendrick B, Stubbs D, McNally MA, Bejon P, Atkins BA, Taylor A, Brent AJ.

J Clin Microbiol. 2018 Nov 27;56(12). pii: e00688-18. doi: 10.1128/JCM.00688-18. Print 2018 Dec.

7.

An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria.

Bhattacharyya N, Nkumama IN, Newland-Smith Z, Lin LY, Yin W, Cullen RE, Griffiths JS, Jarvis AR, Price MJ, Chong PY, Wallis R, O'Hare HM.

MBio. 2018 Jul 31;9(4). pii: e00931-18. doi: 10.1128/mBio.00931-18.

8.

CiPA challenges and opportunities from a non-clinical, clinical and regulatory perspectives. An overview of the safety pharmacology scientific discussion.

Wallis R, Benson C, Darpo B, Gintant G, Kanda Y, Prasad K, Strauss DG, Valentin JP.

J Pharmacol Toxicol Methods. 2018 Sep - Oct;93:15-25. doi: 10.1016/j.vascn.2018.06.005. Epub 2018 Jun 27. Review.

PMID:
29958940
9.

Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection.

Simmons JD, Stein CM, Seshadri C, Campo M, Alter G, Fortune S, Schurr E, Wallis RS, Churchyard G, Mayanja-Kizza H, Boom WH, Hawn TR.

Nat Rev Immunol. 2018 Sep;18(9):575-589. doi: 10.1038/s41577-018-0025-3. Review.

10.

Mycobactericidal activity of bedaquiline plus rifabutin or rifampin in ex vivo whole blood cultures of healthy volunteers: A randomized controlled trial.

Wallis RS, Good CE, O'Riordan MA, Blumer JL, Jacobs MR, Griffiss JM, Healan A, Salata RA.

PLoS One. 2018 May 2;13(5):e0196756. doi: 10.1371/journal.pone.0196756. eCollection 2018.

11.

Reply to Mortensen et al.: The zymogen form of complement component C1.

Almitairi JOM, Venkatraman Girija U, Furze CM, Simpson-Gray X, Badakshi F, Marshall JE, Schwaeble WJ, Mitchell DA, Moody PCE, Wallis R.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3867-E3868. doi: 10.1073/pnas.1804497115. Epub 2018 Apr 13. No abstract available.

12.

Pan-tuberculosis regimens: an argument for.

Wallis RS, Cohen T, Menzies NA, Churchyard G.

Lancet Respir Med. 2018 Apr;6(4):239-240. doi: 10.1016/S2213-2600(18)30096-1. No abstract available.

PMID:
29595501
13.

Structure of the C1r-C1s interaction of the C1 complex of complement activation.

Almitairi JOM, Venkatraman Girija U, Furze CM, Simpson-Gray X, Badakshi F, Marshall JE, Schwaeble WJ, Mitchell DA, Moody PCE, Wallis R.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):768-773. doi: 10.1073/pnas.1718709115. Epub 2018 Jan 8.

14.

Manipulation of cytokine secretion in human dendritic cells using glycopolymers with picomolar affinity for DC-SIGN.

Mitchell DA, Zhang Q, Voorhaar L, Haddleton DM, Herath S, Gleinich AS, Randeva HS, Crispin M, Lehnert H, Wallis R, Patterson S, Becer CR.

Chem Sci. 2017 Oct 1;8(10):6974-6980. doi: 10.1039/c7sc01515a. Epub 2017 Aug 16.

15.

Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population.

Baguma R, Penn-Nicholson A, Smit E, Erasmus M, Day J, Makhethe L, de Kock M, Hughes EJ, van Rooyen M, Pienaar B, Stone L, Hanekom W, Brennan MJ, Wallis RS, Hatherill M, Scriba TJ.

PLoS One. 2017 Sep 8;12(9):e0184563. doi: 10.1371/journal.pone.0184563. eCollection 2017.

16.

Light Scattering By Optically-Trapped Vesicles Affords Unprecedented Temporal Resolution Of Lipid-Raft Dynamics.

Collard L, Perez-Guaita D, Faraj BHA, Wood BR, Wallis R, Andrew PW, Hudson AJ.

Sci Rep. 2017 Aug 17;7(1):8589. doi: 10.1038/s41598-017-08980-1.

17.

External amplitude and frequency modulation of a terahertz quantum cascade laser using metamaterial/graphene devices.

Kindness SJ, Jessop DS, Wei B, Wallis R, Kamboj VS, Xiao L, Ren Y, Braeuninger-Weimer P, Aria AI, Hofmann S, Beere HE, Ritchie DA, Degl'Innocenti R.

Sci Rep. 2017 Aug 9;7(1):7657. doi: 10.1038/s41598-017-07943-w.

18.

An orthologous non-MHC locus in rats and mice is linked to CD4+ and CD8+ T-cell proportion.

Franckaert D, Collin R, Dooley J, Wallis RH, Poussier P, Liston A, Hillhouse EE, Lesage S.

Genes Immun. 2017 Sep;18(3):118-126. doi: 10.1038/gene.2017.9. Epub 2017 May 25.

PMID:
28539651
19.

Methods for selecting regimen duration to prevent relapse in drug-susceptible and drug-resistant TB.

Davies GR, Wallis RS.

Int J Tuberc Lung Dis. 2016 Dec 1;20(12):13-17. doi: 10.5588/ijtld.16.0231.

PMID:
28240567
20.

Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.

Yaseen S, Demopulos G, Dudler T, Yabuki M, Wood CL, Cummings WJ, Tjoelker LW, Fujita T, Sacks S, Garred P, Andrew P, Sim RB, Lachmann PJ, Wallis R, Lynch N, Schwaeble WJ.

FASEB J. 2017 May;31(5):2210-2219. doi: 10.1096/fj.201601306R. Epub 2017 Feb 10.

PMID:
28188176
21.

Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.

Nan R, Furze CM, Wright DW, Gor J, Wallis R, Perkins SJ.

Structure. 2017 Feb 7;25(2):364-375. doi: 10.1016/j.str.2016.12.014. Epub 2017 Jan 19.

22.

High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial.

Boeree MJ, Heinrich N, Aarnoutse R, Diacon AH, Dawson R, Rehal S, Kibiki GS, Churchyard G, Sanne I, Ntinginya NE, Minja LT, Hunt RD, Charalambous S, Hanekom M, Semvua HH, Mpagama SG, Manyama C, Mtafya B, Reither K, Wallis RS, Venter A, Narunsky K, Mekota A, Henne S, Colbers A, van Balen GP, Gillespie SH, Phillips PPJ, Hoelscher M; PanACEA consortium.

Lancet Infect Dis. 2017 Jan;17(1):39-49. doi: 10.1016/S1473-3099(16)30274-2. Epub 2016 Oct 26.

23.

Investigation of hollow cylindrical metal terahertz waveguides suitable for cryogenic environments.

Wallis R, Innocenti RD, Jessop DS, Mitrofanov O, Bledt CM, Melzer JE, Harrington JA, Beere HE, Ritchie DA.

Opt Express. 2016 Dec 26;24(26):30002-30014. doi: 10.1364/OE.24.030002.

PMID:
28059385
24.

Vitamin D as Adjunctive Host-Directed Therapy in Tuberculosis: A Systematic Review.

Wallis RS, Zumla A.

Open Forum Infect Dis. 2016 Sep 7;3(3):ofw151. eCollection 2016 Sep. Review.

25.

Cardiac safety of extensively drug-resistant tuberculosis regimens including bedaquiline, delamanid and clofazimine.

Wallis RS.

Eur Respir J. 2016 Nov;48(5):1526-1527. doi: 10.1183/13993003.01207-2016. No abstract available.

26.

Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series.

Dumas ME, Domange C, Calderari S, Martínez AR, Ayala R, Wilder SP, Suárez-Zamorano N, Collins SC, Wallis RH, Gu Q, Wang Y, Hue C, Otto GW, Argoud K, Navratil V, Mitchell SC, Lindon JC, Holmes E, Cazier JB, Nicholson JK, Gauguier D.

Genome Med. 2016 Sep 30;8(1):101.

27.

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression.

Kaisaki PJ, Otto GW, Argoud K, Collins SC, Wallis RH, Wilder SP, Yau ACY, Hue C, Calderari S, Bihoreau MT, Cazier JB, Mott R, Gauguier D.

G3 (Bethesda). 2016 Nov 8;6(11):3671-3683. doi: 10.1534/g3.116.033274.

28.

The relative contributions of psychiatric symptoms and psychotropic medications on the sleep-wake profile of young persons with anxiety, depression and bipolar disorders.

Robillard R, Oxley C, Hermens DF, White D, Wallis R, Naismith SL, Whitwell B, Southan J, Scott EM, Hickie IB.

Psychiatry Res. 2016 Sep 30;243:403-6. doi: 10.1016/j.psychres.2016.06.025. Epub 2016 Jun 17.

PMID:
27449011
29.

Safety and Immunogenicity of the Recombinant BCG Vaccine AERAS-422 in Healthy BCG-naïve Adults: A Randomized, Active-controlled, First-in-human Phase 1 Trial.

Hoft DF, Blazevic A, Selimovic A, Turan A, Tennant J, Abate G, Fulkerson J, Zak DE, Walker R, McClain B, Sadoff J, Scott J, Shepherd B, Ishmukhamedov J, Hokey DA, Dheenadhayalan V, Shankar S, Amon L, Navarro G, Podyminogin R, Aderem A, Barker L, Brennan M, Wallis RS, Gershon AA, Gershon MD, Steinberg S.

EBioMedicine. 2016 May;7:278-86. doi: 10.1016/j.ebiom.2016.04.010. Epub 2016 Apr 19.

30.

Mathematical Models of Tuberculosis Reactivation and Relapse.

Wallis RS.

Front Microbiol. 2016 May 17;7:669. doi: 10.3389/fmicb.2016.00669. eCollection 2016.

31.

Activity of nitazoxanide and tizoxanide against Mycobacterium tuberculosis in vitro and in whole blood culture.

Harausz EP, Chervenak KA, Good CE, Jacobs MR, Wallis RS, Sanchez-Felix M, Boom WH; TB Research Unit (TBRU) at Case Western Reserve University.

Tuberculosis (Edinb). 2016 May;98:92-6. doi: 10.1016/j.tube.2016.03.002. Epub 2016 Mar 22.

32.

Host-directed therapies for infectious diseases: current status, recent progress, and future prospects.

Zumla A, Rao M, Wallis RS, Kaufmann SH, Rustomjee R, Mwaba P, Vilaplana C, Yeboah-Manu D, Chakaya J, Ippolito G, Azhar E, Hoelscher M, Maeurer M; Host-Directed Therapies Network consortium.

Lancet Infect Dis. 2016 Apr;16(4):e47-63. doi: 10.1016/S1473-3099(16)00078-5. Review.

PMID:
27036359
33.

Tuberculosis--advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers.

Wallis RS, Maeurer M, Mwaba P, Chakaya J, Rustomjee R, Migliori GB, Marais B, Schito M, Churchyard G, Swaminathan S, Hoelscher M, Zumla A.

Lancet Infect Dis. 2016 Apr;16(4):e34-46. doi: 10.1016/S1473-3099(16)00070-0. Review.

PMID:
27036358
34.

World TB Day 2016: reflections on the global TB emergency.

Zumla A, Schito M, Chakaya J, Marais B, Mwaba P, Migliori GB, Hoelscher M, Maeurer M, Wallis RS.

Lancet Respir Med. 2016 Apr;4(4):249-51. doi: 10.1016/S2213-2600(16)00066-7. Epub 2016 Mar 23. Review. No abstract available.

PMID:
27016869
35.

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.

Pilecki B, Holm AT, Schlosser A, Moeller JB, Wohl AP, Zuk AV, Heumüller SE, Wallis R, Moestrup SK, Sengle G, Holmskov U, Sorensen GL.

J Biol Chem. 2016 Jan 15;291(3):1103-14. doi: 10.1074/jbc.M115.681775. Epub 2015 Nov 24.

36.

Efficient coupling of double-metal terahertz quantum cascade lasers to flexible dielectric-lined hollow metallic waveguides.

Wallis R, Degl'Iinnocenti R, Jessop DS, Ren Y, Klimont A, Shah YD, Mitrofanov O, Bledt CM, Melzer JE, Harrington JA, Beere HE, Ritchie DA.

Opt Express. 2015 Oct 5;23(20):26276-87. doi: 10.1364/OE.23.026276.

PMID:
26480141
37.

Early Biomarkers and Regulatory Innovation in Multidrug-Resistant Tuberculosis.

Wallis RS, Peppard T.

Clin Infect Dis. 2015 Oct 15;61Suppl 3:S160-3. doi: 10.1093/cid/civ612.

PMID:
26409278
38.

The Crystal Structure of Pneumolysin at 2.0 Å Resolution Reveals the Molecular Packing of the Pre-pore Complex.

Marshall JE, Faraj BH, Gingras AR, Lonnen R, Sheikh MA, El-Mezgueldi M, Moody PC, Andrew PW, Wallis R.

Sci Rep. 2015 Sep 3;5:13293. doi: 10.1038/srep13293.

39.

Towards host-directed therapies for tuberculosis.

Zumla A, Maeurer M; Host-Directed Therapies Network, Chakaya J, Hoelscher M, Ntoumi F, Rustomjee R, Vilaplana C, Yeboah-Manu D, Rasolof V, Munderi P, Singh N, Aklillu E, Padayatchi N, Macete E, Kapata N, Mulenga M, Kibiki G, Mfinanga S, Nyirenda T, Maboko L, Garcia-Basteiro A, Rakotosamimanana N, Bates M, Mwaba P, Reither K, Gagneux S, Edwards S, Mfinanga E, Abdulla S, Cardona PJ, Russell JB, Gant V, Noursadeghi M, Elkington P, Bonnet M, Menendez C, Dieye TN, Diarra B, Maiga A, Aseffa A, Parida S, Wejse C, Petersen E, Kaleebu P, Oliver M, Craig G, Corrah T, Tientcheu L, Antonio M, Rao M, McHugh TD, Sheikh A, Ippolito G, Ramjee G, Kaufmann SH, Churchyard G, Steyn A, Grobusch M, Sanne I, Martinson N, Madansein R, Wilkinson RJ, Mayosi B, Schito M, Wallis RS.

Nat Rev Drug Discov. 2015 Aug;14(8):511-2. doi: 10.1038/nrd4696. Epub 2015 Jul 17.

PMID:
26184493
40.

H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses.

Bidula S, Sexton DW, Yates M, Abdolrasouli A, Shah A, Wallis R, Reed A, Armstrong-James D, Schelenz S.

Immunology. 2015 Oct;146(2):281-91. doi: 10.1111/imm.12501. Epub 2015 Aug 24.

41.

Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain.

Semblat JP, Ghumra A, Czajkowsky DM, Wallis R, Mitchell DA, Raza A, Rowe JA.

Mol Biochem Parasitol. 2015 May;201(1):76-82. doi: 10.1016/j.molbiopara.2015.06.001. Epub 2015 Jun 18.

42.

Sputum culture conversion in new TB regimens.

Wallis RS.

Lancet Respir Med. 2015 Jun;3(6):e18-9. doi: 10.1016/S2213-2600(15)00182-4. No abstract available.

PMID:
26065975
43.

Predictivity of in vitro non-clinical cardiac contractility assays for inotropic effects in humans--A literature search.

Wallis R, Gharanei M, Maddock H.

J Pharmacol Toxicol Methods. 2015 Sep-Oct;75:62-9. doi: 10.1016/j.vascn.2015.05.009. Epub 2015 May 27. Review.

PMID:
26026903
44.

Month 2 culture status and treatment duration as predictors of recurrence in pulmonary tuberculosis: model validation and update.

Wallis RS, Peppard T, Hermann D.

PLoS One. 2015 Apr 29;10(4):e0125403. doi: 10.1371/journal.pone.0125403. eCollection 2015.

45.

Molecular basis of sugar recognition by collectin-K1 and the effects of mutations associated with 3MC syndrome.

Venkatraman Girija U, Furze CM, Gingras AR, Yoshizaki T, Ohtani K, Marshall JE, Wallis AK, Schwaeble WJ, El-Mezgueldi M, Mitchell DA, Moody PC, Wakamiya N, Wallis R.

BMC Biol. 2015 Apr 17;13:27. doi: 10.1186/s12915-015-0136-2.

46.

Advancing host-directed therapy for tuberculosis.

Wallis RS, Hafner R.

Nat Rev Immunol. 2015 Apr;15(4):255-63. doi: 10.1038/nri3813. Epub 2015 Mar 13. Review.

PMID:
25765201
47.

Corticosteroid effects on sputum culture in pulmonary tuberculosis: a meta-regression analysis.

Wallis RS.

Open Forum Infect Dis. 2014 Jun 3;1(1):ofu020. doi: 10.1093/ofid/ofu020. eCollection 2014 Mar.

48.

Sputum culture conversion as a tuberculosis biomarker: a glass half empty or half full?

Wallis RS.

Lancet Respir Med. 2015 Mar;3(3):174-5. doi: 10.1016/S2213-2600(15)00058-2. Epub 2015 Feb 26. No abstract available.

PMID:
25726087
49.

Long-Term Follow-up to a Randomized Controlled Trial Comparing Peroneal Nerve Functional Electrical Stimulation to an Ankle Foot Orthosis for Patients With Chronic Stroke.

Bethoux F, Rogers HL, Nolan KJ, Abrams GM, Annaswamy T, Brandstater M, Browne B, Burnfield JM, Feng W, Freed MJ, Geis C, Greenberg J, Gudesblatt M, Ikramuddin F, Jayaraman A, Kautz SA, Lutsep HL, Madhavan S, Meilahn J, Pease WS, Rao N, Seetharama S, Sethi P, Turk MA, Wallis RA, Kufta C.

Neurorehabil Neural Repair. 2015 Nov-Dec;29(10):911-22. doi: 10.1177/1545968315570325. Epub 2015 Feb 4.

PMID:
25653225
50.

A functional polymorphism of Ptpn22 is associated with type 1 diabetes in the BioBreeding rat.

Sarmiento J, Wallis RH, Ning T, Marandi L, Chao G, Veillette A, Lernmark Å, Paterson AD, Poussier P.

J Immunol. 2015 Jan 15;194(2):615-29. doi: 10.4049/jimmunol.1302689. Epub 2014 Dec 12.

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