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Items: 1 to 50 of 225

1.

Pulmonary toxicity of two different multi-walled carbon nanotubes in rat: Comparison between intratracheal instillation and inhalation exposure.

Gaté L, Knudsen KB, Seidel C, Berthing T, Chézeau L, Jacobsen NR, Valentino S, Wallin H, Bau S, Wolff H, Sébillaud S, Lorcin M, Grossmann S, Viton S, Nunge H, Darne C, Vogel U, Cosnier F.

Toxicol Appl Pharmacol. 2019 Jul 15;375:17-31. doi: 10.1016/j.taap.2019.05.001. Epub 2019 May 7. Spanish.

PMID:
31075343
2.

Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses.

Hadrup N, Knudsen KB, Berthing T, Wolff H, Bengtson S, Kofoed C, Espersen R, Højgaard C, Winther JR, Willemoës M, Wedin I, Nuopponen M, Alenius H, Norppa H, Wallin H, Vogel U.

Environ Toxicol Pharmacol. 2019 Feb;66:116-125. doi: 10.1016/j.etap.2019.01.003. Epub 2019 Jan 14.

PMID:
30665014
3.

Gradual reduction in exercise capacity in chronic kidney disease is associated with systemic oxygen delivery factors.

Wallin H, Asp AM, Wallquist C, Jansson E, Caidahl K, Hylander Rössner B, Jacobson SH, Rickenlund A, Eriksson MJ.

PLoS One. 2018 Dec 19;13(12):e0209325. doi: 10.1371/journal.pone.0209325. eCollection 2018.

4.

Corrigendum to Does intranasal instillation TiO2 cause pulmonary tumorigenesis in male mice?

Møller P, Wallin H, Cassee FR, Loft S.

Environ Toxicol. 2018 Nov;33(11):1214. doi: 10.1002/tox.22666. Epub 2018 Sep 26. No abstract available.

PMID:
30259630
5.

Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation.

Mech A, Rasmussen K, Jantunen P, Aicher L, Alessandrelli M, Bernauer U, Bleeker EAJ, Bouillard J, Di Prospero Fanghella P, Draisci R, Dusinska M, Encheva G, Flament G, Haase A, Handzhiyski Y, Herzberg F, Huwyler J, Jacobsen NR, Jeliazkov V, Jeliazkova N, Nymark P, Grafström R, Oomen AG, Polci ML, Riebeling C, Sandström J, Shivachev B, Stateva S, Tanasescu S, Tsekovska R, Wallin H, Wilks MF, Zellmer S, Apostolova MD.

Nanotoxicology. 2019 Feb;13(1):119-141. doi: 10.1080/17435390.2018.1513092. Epub 2018 Sep 5.

PMID:
30182766
6.

Physicochemical predictors of Multi-Walled Carbon Nanotube-induced pulmonary histopathology and toxicity one year after pulmonary deposition of 11 different Multi-Walled Carbon Nanotubes in mice.

Knudsen KB, Berthing T, Jackson P, Poulsen SS, Mortensen A, Jacobsen NR, Skaug V, Szarek J, Hougaard KS, Wolff H, Wallin H, Vogel U.

Basic Clin Pharmacol Toxicol. 2019 Feb;124(2):211-227. doi: 10.1111/bcpt.13119. Epub 2018 Oct 18.

PMID:
30168672
7.

Corrigendum to "MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs" [Toxicol. Appl. Pharmacol., 284 (2015) 16-32].

Poulsen SS, Saber AT, Williams A, Andersen O, Købler C, Atluri R, Pozzebon ME, Mucelli SP, Simion M, Rickerby D, Mortensen A, Jackson P, Kyjovska ZO, Mølhave K, Jacobsen NR, Jensen KA, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2018 Sep 15;355:286. doi: 10.1016/j.taap.2018.06.006. Epub 2018 Jun 13. No abstract available.

8.

Toxicity of pristine and paint-embedded TiO2 nanomaterials.

Saber AT, Mortensen A, Szarek J, Jacobsen NR, Levin M, Koponen IK, Jensen KA, Vogel U, Wallin H.

Hum Exp Toxicol. 2019 Jan;38(1):11-24. doi: 10.1177/0960327118774910. Epub 2018 May 16.

PMID:
29766753
9.

Influence of dispersion medium on nanomaterial-induced pulmonary inflammation and DNA strand breaks: investigation of carbon black, carbon nanotubes and three titanium dioxide nanoparticles.

Hadrup N, Bengtson S, Jacobsen NR, Jackson P, Nocun M, Saber AT, Jensen KA, Wallin H, Vogel U.

Mutagenesis. 2017 Dec 31;32(6):581-597. doi: 10.1093/mutage/gex042.

10.

To be or not to be a subspecies: description of Saperda populnea lapponica ssp. n. (Coleoptera, Cerambycidae) developing in downy willow (Salix lapponum L.).

Wallin H, Kvamme T, Bergsten J.

Zookeys. 2017 Aug 17;(691):103-148. doi: 10.3897/zookeys.691.12880. eCollection 2017.

11.

Does intranasal instillation TiO2 cause pulmonary tumorigenesis in male mice?

Møller P, Wallin H, Cassee FR, Loft S.

Environ Toxicol. 2018 Nov;33(11):1095-1096. doi: 10.1002/tox.22490. Epub 2017 Oct 21. No abstract available. Erratum in: Environ Toxicol. 2018 Sep 26;:.

PMID:
29055161
12.

Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis.

Rahman L, Jacobsen NR, Aziz SA, Wu D, Williams A, Yauk CL, White P, Wallin H, Vogel U, Halappanavar S.

Mutat Res. 2017 Nov;823:28-44. doi: 10.1016/j.mrgentox.2017.08.005. Epub 2017 Sep 8.

13.

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework.

Nikota J, Banville A, Goodwin LR, Wu D, Williams A, Yauk CL, Wallin H, Vogel U, Halappanavar S.

Part Fibre Toxicol. 2017 Sep 13;14(1):37. doi: 10.1186/s12989-017-0218-0.

14.

Low-level internalization of cystatin E/M affects legumain activity and migration of melanoma cells.

Wallin H, Apelqvist J, Andersson F, Ekström U, Abrahamson M.

J Biol Chem. 2017 Sep 1;292(35):14413-14424. doi: 10.1074/jbc.M117.776138. Epub 2017 Jun 19.

15.

Multi-walled carbon nanotube-physicochemical properties predict the systemic acute phase response following pulmonary exposure in mice.

Poulsen SS, Knudsen KB, Jackson P, Weydahl IE, Saber AT, Wallin H, Vogel U.

PLoS One. 2017 Apr 5;12(4):e0174167. doi: 10.1371/journal.pone.0174167. eCollection 2017.

16.

Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo.

Bornholdt J, Saber AT, Lilje B, Boyd M, Jørgensen M, Chen Y, Vitezic M, Jacobsen NR, Poulsen SS, Berthing T, Bressendorff S, Vitting-Seerup K, Andersson R, Hougaard KS, Yauk CL, Halappanavar S, Wallin H, Vogel U, Sandelin A.

ACS Nano. 2017 Apr 25;11(4):3597-3613. doi: 10.1021/acsnano.6b07533. Epub 2017 Mar 31.

PMID:
28345861
17.

Promise and peril in nanomedicine: the challenges and needs for integrated systems biology approaches to define health risk.

Halappanavar S, Vogel U, Wallin H, Yauk CL.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 Jan;10(1). doi: 10.1002/wnan.1465. Epub 2017 Mar 15. Review.

18.

Biodistribution of Carbon Nanotubes in Animal Models.

Jacobsen NR, Møller P, Clausen PA, Saber AT, Micheletti C, Jensen KA, Wallin H, Vogel U.

Basic Clin Pharmacol Toxicol. 2017 Sep;121 Suppl 3:30-43. doi: 10.1111/bcpt.12705. Epub 2017 Feb 22. Review.

19.

Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice.

Christophersen DV, Jacobsen NR, Andersen MH, Connell SP, Barfod KK, Thomsen MB, Miller MR, Duffin R, Lykkesfeldt J, Vogel U, Wallin H, Loft S, Roursgaard M, Møller P.

Toxicology. 2016 Sep 14;371:29-40. doi: 10.1016/j.tox.2016.10.003. Epub 2016 Oct 8.

20.

Surface modification does not influence the genotoxic and inflammatory effects of TiO2 nanoparticles after pulmonary exposure by instillation in mice.

Wallin H, Kyjovska ZO, Poulsen SS, Jacobsen NR, Saber AT, Bengtson S, Jackson P, Vogel U.

Mutagenesis. 2017 Jan;32(1):47-57. doi: 10.1093/mutage/gew046. Epub 2016 Sep 22.

21.

Inflammation and Vascular Effects after Repeated Intratracheal Instillations of Carbon Black and Lipopolysaccharide.

Christophersen DV, Jacobsen NR, Jensen DM, Kermanizadeh A, Sheykhzade M, Loft S, Vogel U, Wallin H, Møller P.

PLoS One. 2016 Aug 29;11(8):e0160731. doi: 10.1371/journal.pone.0160731. eCollection 2016.

22.

Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition.

Saber AT, Mortensen A, Szarek J, Koponen IK, Levin M, Jacobsen NR, Pozzebon ME, Mucelli SP, Rickerby DG, Kling K, Atluri R, Madsen AM, Jackson P, Kyjovska ZO, Vogel U, Jensen KA, Wallin H.

Part Fibre Toxicol. 2016 Jun 29;13(1):37. doi: 10.1186/s12989-016-0148-2.

23.

Airway irritation, inflammation, and toxicity in mice following inhalation of metal oxide nanoparticles.

Larsen ST, Jackson P, Poulsen SS, Levin M, Jensen KA, Wallin H, Nielsen GD, Koponen IK.

Nanotoxicology. 2016 Nov;10(9):1254-62. doi: 10.1080/17435390.2016.1202350. Epub 2016 Jul 18.

24.

Multi-walled carbon nanotube physicochemical properties predict pulmonary inflammation and genotoxicity.

Poulsen SS, Jackson P, Kling K, Knudsen KB, Skaug V, Kyjovska ZO, Thomsen BL, Clausen PA, Atluri R, Berthing T, Bengtson S, Wolff H, Jensen KA, Wallin H, Vogel U.

Nanotoxicology. 2016 Nov;10(9):1263-75. doi: 10.1080/17435390.2016.1202351. Epub 2016 Jul 7.

25.

No cytotoxicity or genotoxicity of graphene and graphene oxide in murine lung epithelial FE1 cells in vitro.

Bengtson S, Kling K, Madsen AM, Noergaard AW, Jacobsen NR, Clausen PA, Alonso B, Pesquera A, Zurutuza A, Ramos R, Okuno H, Dijon J, Wallin H, Vogel U.

Environ Mol Mutagen. 2016 Jul;57(6):469-82. doi: 10.1002/em.22017. Epub 2016 May 17.

26.

Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials.

Nikota J, Williams A, Yauk CL, Wallin H, Vogel U, Halappanavar S.

Part Fibre Toxicol. 2016 May 11;13(1):25. doi: 10.1186/s12989-016-0137-5.

27.

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health--ENPRA Project--The Highlights, Limitations, and Current and Future Challenges.

Kermanizadeh A, Gosens I, MacCalman L, Johnston H, Danielsen PH, Jacobsen NR, Lenz AG, Fernandes T, Schins RP, Cassee FR, Wallin H, Kreyling W, Stoeger T, Loft S, Møller P, Tran L, Stone V.

J Toxicol Environ Health B Crit Rev. 2016;19(1):1-28. doi: 10.1080/10937404.2015.1126210. Review.

PMID:
27030582
28.

Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes.

Labib S, Williams A, Yauk CL, Nikota JK, Wallin H, Vogel U, Halappanavar S.

Part Fibre Toxicol. 2016 Mar 15;13:15. doi: 10.1186/s12989-016-0125-9.

29.

A review of the genus Potemnemus Thomson, 1864 (Coleoptera: Cerambycidae) with description of a new species from Papua New Guinea.

Wallin H, Kvamme T.

Zootaxa. 2015 Nov 13;4040(5):501-29. doi: 10.11646/zootaxa.4040.5.1.

PMID:
26624687
30.

Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation.

Husain M, Kyjovska ZO, Bourdon-Lacombe J, Saber AT, Jensen KA, Jacobsen NR, Williams A, Wallin H, Halappanavar S, Vogel U, Yauk CL.

Toxicol Appl Pharmacol. 2015 Dec 15;289(3):573-88. doi: 10.1016/j.taap.2015.11.003. Epub 2015 Nov 10.

PMID:
26551751
31.

Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories.

Jacobsen NR, Stoeger T, van den Brule S, Saber AT, Beyerle A, Vietti G, Mortensen A, Szarek J, Budtz HC, Kermanizadeh A, Banerjee A, Ercal N, Vogel U, Wallin H, Møller P.

Food Chem Toxicol. 2015 Nov;85:84-95. doi: 10.1016/j.fct.2015.08.008. Epub 2015 Aug 7.

32.

Visualization of Nanofibrillar Cellulose in Biological Tissues Using a Biotinylated Carbohydrate Binding Module of β-1,4-Glycanase.

Knudsen KB, Kofoed C, Espersen R, Højgaard C, Winther JR, Willemoës M, Wedin I, Nuopponen M, Vilske S, Aimonen K, Weydahl IE, Alenius H, Norppa H, Wolff H, Wallin H, Vogel U.

Chem Res Toxicol. 2015 Aug 17;28(8):1627-35. doi: 10.1021/acs.chemrestox.5b00271. Epub 2015 Aug 6.

PMID:
26208679
33.

Nanomaterial translocation--the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs--a review.

Kermanizadeh A, Balharry D, Wallin H, Loft S, Møller P.

Crit Rev Toxicol. 2015;45(10):837-72. doi: 10.3109/10408444.2015.1058747. Epub 2015 Jul 3. Review.

PMID:
26140391
34.

Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice.

Husain M, Wu D, Saber AT, Decan N, Jacobsen NR, Williams A, Yauk CL, Wallin H, Vogel U, Halappanavar S.

Nanotoxicology. 2015;9(8):1013-22. doi: 10.3109/17435390.2014.996192. Epub 2015 May 20.

35.

Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice.

Gosens I, Kermanizadeh A, Jacobsen NR, Lenz AG, Bokkers B, de Jong WH, Krystek P, Tran L, Stone V, Wallin H, Stoeger T, Cassee FR.

PLoS One. 2015 May 12;10(5):e0126934. doi: 10.1371/journal.pone.0126934. eCollection 2015.

36.

DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice.

Kyjovska ZO, Jacobsen NR, Saber AT, Bengtson S, Jackson P, Wallin H, Vogel U.

Mutagenesis. 2015 Jul;30(4):499-507. doi: 10.1093/mutage/gev009. Epub 2015 Mar 14.

PMID:
25771385
37.

Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease.

Poulsen SS, Saber AT, Mortensen A, Szarek J, Wu D, Williams A, Andersen O, Jacobsen NR, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2015 Mar 15;283(3):210-22. doi: 10.1016/j.taap.2015.01.011. Epub 2015 Jan 22.

38.

Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice.

Købler C, Poulsen SS, Saber AT, Jacobsen NR, Wallin H, Yauk CL, Halappanavar S, Vogel U, Qvortrup K, Mølhave K.

PLoS One. 2015 Jan 23;10(1):e0116481. doi: 10.1371/journal.pone.0116481. eCollection 2015.

39.

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs.

Poulsen SS, Saber AT, Williams A, Andersen O, Købler C, Atluri R, Pozzebon ME, Mucelli SP, Simion M, Rickerby D, Mortensen A, Jackson P, Kyjovska ZO, Mølhave K, Jacobsen NR, Jensen KA, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2015 Apr 1;284(1):16-32. doi: 10.1016/j.taap.2014.12.011. Epub 2014 Dec 29. Erratum in: Toxicol Appl Pharmacol. 2018 Sep 15;355:286.

40.

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response.

Halappanavar S, Saber AT, Decan N, Jensen KA, Wu D, Jacobsen NR, Guo C, Rogowski J, Koponen IK, Levin M, Madsen AM, Atluri R, Snitka V, Birkedal RK, Rickerby D, Williams A, Wallin H, Yauk CL, Vogel U.

Environ Mol Mutagen. 2015 Mar;56(2):245-64. doi: 10.1002/em.21936. Epub 2014 Dec 11.

PMID:
25504612
41.

Characterization of genotoxic response to 15 multiwalled carbon nanotubes with variable physicochemical properties including surface functionalizations in the FE1-Muta(TM) mouse lung epithelial cell line.

Jackson P, Kling K, Jensen KA, Clausen PA, Madsen AM, Wallin H, Vogel U.

Environ Mol Mutagen. 2015 Mar;56(2):183-203. doi: 10.1002/em.21922. Epub 2014 Nov 12.

PMID:
25393212
42.

DNA damage following pulmonary exposure by instillation to low doses of carbon black (Printex 90) nanoparticles in mice.

Kyjovska ZO, Jacobsen NR, Saber AT, Bengtson S, Jackson P, Wallin H, Vogel U.

Environ Mol Mutagen. 2015 Jan;56(1):41-9. doi: 10.1002/em.21888. Epub 2014 Jul 18.

43.

Comparison of dust release from epoxy and paint nanocomposites and conventional products during sanding and sawing.

Gomez V, Levin M, Saber AT, Irusta S, Dal Maso M, Hanoi R, Santamaria J, Jensen KA, Wallin H, Koponen IK.

Ann Occup Hyg. 2014 Oct;58(8):983-94. doi: 10.1093/annhyg/meu046. Epub 2014 Jul 16.

PMID:
25030708
44.

Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats.

Geraets L, Oomen AG, Krystek P, Jacobsen NR, Wallin H, Laurentie M, Verharen HW, Brandon EF, de Jong WH.

Part Fibre Toxicol. 2014 Jul 3;11:30. doi: 10.1186/1743-8977-11-30.

45.

Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease.

Saber AT, Jacobsen NR, Jackson P, Poulsen SS, Kyjovska ZO, Halappanavar S, Yauk CL, Wallin H, Vogel U.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014 Nov-Dec;6(6):517-31. doi: 10.1002/wnan.1279. Epub 2014 Jun 12. Review.

46.

ITS-NANO--prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy.

Stone V, Pozzi-Mucelli S, Tran L, Aschberger K, Sabella S, Vogel U, Poland C, Balharry D, Fernandes T, Gottardo S, Hankin S, Hartl MG, Hartmann N, Hristozov D, Hund-Rinke K, Johnston H, Marcomini A, Panzer O, Roncato D, Saber AT, Wallin H, Scott-Fordsmand JJ.

Part Fibre Toxicol. 2014 Feb 13;11:9. doi: 10.1186/1743-8977-11-9.

47.

FIB-SEM imaging of carbon nanotubes in mouse lung tissue.

Købler C, Saber AT, Jacobsen NR, Wallin H, Vogel U, Qvortrup K, Mølhave K.

Anal Bioanal Chem. 2014 Jun;406(16):3863-73. doi: 10.1007/s00216-013-7566-x. Epub 2014 Jan 22.

48.

Vascular effects of multiwalled carbon nanotubes in dyslipidemic ApoE-/- mice and cultured endothelial cells.

Cao Y, Jacobsen NR, Danielsen PH, Lenz AG, Stoeger T, Loft S, Wallin H, Roursgaard M, Mikkelsen L, Møller P.

Toxicol Sci. 2014 Mar;138(1):104-16. doi: 10.1093/toxsci/kft328. Epub 2014 Jan 15.

PMID:
24431218
49.

Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells.

Søs Poulsen S, Jacobsen NR, Labib S, Wu D, Husain M, Williams A, Bøgelund JP, Andersen O, Købler C, Mølhave K, Kyjovska ZO, Saber AT, Wallin H, Yauk CL, Vogel U, Halappanavar S.

PLoS One. 2013 Nov 19;8(11):e80452. doi: 10.1371/journal.pone.0080452. eCollection 2013.

50.

Validation of freezing tissues and cells for analysis of DNA strand break levels by comet assay.

Jackson P, Pedersen LM, Kyjovska ZO, Jacobsen NR, Saber AT, Hougaard KS, Vogel U, Wallin H.

Mutagenesis. 2013 Nov;28(6):699-707. doi: 10.1093/mutage/get049. Epub 2013 Oct 17.

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