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Items: 9

1.

Notch3 is necessary for blood vessel integrity in the central nervous system.

Henshall TL, Keller A, He L, Johansson BR, Wallgard E, Raschperger E, Mäe MA, Jin S, Betsholtz C, Lendahl U.

Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):409-20. doi: 10.1161/ATVBAHA.114.304849. Epub 2014 Dec 4.

PMID:
25477343
2.

Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development.

Wallgard E, Nitzsche A, Larsson J, Guo X, Dieterich LC, Dimberg A, Olofsson T, Pontén FC, Mäkinen T, Kalén M, Hellström M.

Dev Dyn. 2012 Apr;241(4):770-86. doi: 10.1002/dvdy.23753. Epub 2012 Feb 21.

3.

Pericytes regulate the blood-brain barrier.

Armulik A, Genové G, Mäe M, Nisancioglu MH, Wallgard E, Niaudet C, He L, Norlin J, Lindblom P, Strittmatter K, Johansson BR, Betsholtz C.

Nature. 2010 Nov 25;468(7323):557-61. doi: 10.1038/nature09522. Epub 2010 Oct 13.

PMID:
20944627
4.

Therapeutic efficacy of a DNA vaccine targeting the endothelial tip cell antigen delta-like ligand 4 in mammary carcinoma.

Haller BK, Bråve A, Wallgard E, Roswall P, Sunkari VG, Mattson U, Hallengärd D, Catrina SB, Hellström M, Pietras K.

Oncogene. 2010 Jul 29;29(30):4276-86. doi: 10.1038/onc.2010.176. Epub 2010 May 24.

PMID:
20498640
5.

Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.

Kalén M, Wallgard E, Asker N, Nasevicius A, Athley E, Billgren E, Larson JD, Wadman SA, Norseng E, Clark KJ, He L, Karlsson-Lindahl L, Häger AK, Weber H, Augustin H, Samuelsson T, Kemmet CK, Utesch CM, Essner JJ, Hackett PB, Hellström M.

Chem Biol. 2009 Apr 24;16(4):432-41. doi: 10.1016/j.chembiol.2009.02.010.

6.

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.

Tammela T, Zarkada G, Wallgard E, Murtomäki A, Suchting S, Wirzenius M, Waltari M, Hellström M, Schomber T, Peltonen R, Freitas C, Duarte A, Isoniemi H, Laakkonen P, Christofori G, Ylä-Herttuala S, Shibuya M, Pytowski B, Eichmann A, Betsholtz C, Alitalo K.

Nature. 2008 Jul 31;454(7204):656-60. doi: 10.1038/nature07083. Epub 2008 Jun 25.

PMID:
18594512
7.

Identification of a core set of 58 gene transcripts with broad and specific expression in the microvasculature.

Wallgard E, Larsson E, He L, Hellström M, Armulik A, Nisancioglu MH, Genove G, Lindahl P, Betsholtz C.

Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1469-76. doi: 10.1161/ATVBAHA.108.165738. Epub 2008 May 15.

PMID:
18483404
8.

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.

Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalén M, Gerhardt H, Betsholtz C.

Nature. 2007 Feb 15;445(7129):776-80. Epub 2007 Jan 28.

PMID:
17259973
9.

Large-scale identification of genes implicated in kidney glomerulus development and function.

Takemoto M, He L, Norlin J, Patrakka J, Xiao Z, Petrova T, Bondjers C, Asp J, Wallgard E, Sun Y, Samuelsson T, Mostad P, Lundin S, Miura N, Sado Y, Alitalo K, Quaggin SE, Tryggvason K, Betsholtz C.

EMBO J. 2006 Mar 8;25(5):1160-74. Epub 2006 Feb 23.

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