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Items: 1 to 50 of 253

1.

Causal Inference for Genetically Determined Levels of HDL (High-Density Lipoprotein) Cholesterol and Risk of Infectious Disease.

Trinder M, Walley KR, Boyd JH, Brunham LR.

Arterioscler Thromb Vasc Biol. 2019 Nov 7:ATVBAHA119313381. doi: 10.1161/ATVBAHA.119.313381. [Epub ahead of print]

PMID:
31694394
2.

Very Low Density Lipoprotein Receptor Sequesters Lipopolysaccharide Into Adipose Tissue During Sepsis.

Shimada T, Topchiy E, Leung AKK, Kong HJ, Genga KR, Boyd JH, Russell JA, Oda S, Nakada TA, Hirasawa H, Walley KR.

Crit Care Med. 2019 Oct 23. doi: 10.1097/CCM.0000000000004064. [Epub ahead of print]

PMID:
31651422
3.

Discovering Causal Mechanistic Pathways in Sepsis-Associated ARDS.

Walley KR.

Am J Respir Crit Care Med. 2019 Sep 23. doi: 10.1164/rccm.201909-1772ED. [Epub ahead of print] No abstract available.

PMID:
31545649
4.

Reduced Proprotein convertase subtilisin/kexin 9 (PCSK9) function increases lipoteichoic acid clearance and improves outcomes in Gram positive septic shock patients.

Leung AKK, Genga KR, Topchiy E, Cirstea M, Shimada T, Fjell C, Russell JA, Boyd JH, Walley KR.

Sci Rep. 2019 Jul 22;9(1):10588. doi: 10.1038/s41598-019-46745-0.

5.

Sepsis-Induced Myocardial Dysfunction and Mammalian Target of Rapamycin Signalling Pathways.

Walley KR.

Can J Cardiol. 2019 Jul;35(7):809-812. doi: 10.1016/j.cjca.2019.04.003. Epub 2019 Apr 12. No abstract available.

PMID:
31292076
6.

The Specific Organism: Not Bacterial Gram Type: Drives the Inflammatory Response in Septic Shock.

Linder A, Fjell CD, Inghammar M, Hsu J, Walley KR, Boyd JH, Russell JA.

J Innate Immun. 2019 Jun 26:1-9. doi: 10.1159/000500418. [Epub ahead of print]

7.

Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials.

Nagendran M, Russell JA, Walley KR, Brett SJ, Perkins GD, Hajjar L, Mason AJ, Ashby D, Gordon AC.

Intensive Care Med. 2019 Jun;45(6):844-855. doi: 10.1007/s00134-019-05620-2. Epub 2019 May 6. Review.

PMID:
31062052
8.

Lower 90-day Hospital Readmission Rates for Esophageal Variceal Bleeding After TIPS: A Nationwide Linked Analysis.

Rush B, Deol N, Teriyaki A, Sey M, Jairath V, Walley KR, Celi LA, Brahmania M.

J Clin Gastroenterol. 2019 Feb 27. doi: 10.1097/MCG.0000000000001199. [Epub ahead of print]

PMID:
30829905
9.

Outcomes of in-hospital cardiopulmonary resuscitation for patients with end-stage liver disease.

Ufere NN, Brahmania M, Sey M, Teriaky A, El-Jawahri A, Walley KR, Celi LA, Chung RT, Rush B.

Liver Int. 2019 Jul;39(7):1256-1262. doi: 10.1111/liv.14079. Epub 2019 Mar 26.

PMID:
30809903
10.

Vasopressin in Vasodilatory Shock.

Ukor IF, Walley KR.

Crit Care Clin. 2019 Apr;35(2):247-261. doi: 10.1016/j.ccc.2018.11.004. Epub 2019 Jan 23. Review.

PMID:
30784607
11.

Palliative medicine and hospital readmissions in end-stage liver disease.

Rush B, Fruhstofer C, Walley KR, Celi LA, Brahmania M.

BMJ Support Palliat Care. 2019 Feb 13. pii: bmjspcare-2018-001635. doi: 10.1136/bmjspcare-2018-001635. [Epub ahead of print]

PMID:
30760459
12.

Challenges in the management of septic shock: a narrative review.

De Backer D, Cecconi M, Lipman J, Machado F, Myatra SN, Ostermann M, Perner A, Teboul JL, Vincent JL, Walley KR.

Intensive Care Med. 2019 Apr;45(4):420-433. doi: 10.1007/s00134-019-05544-x. Epub 2019 Feb 11. Review.

PMID:
30741328
13.

Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients.

Schlosser K, Wang JP, Dos Santos C, Walley KR, Marshall J, Fergusson DA, Winston BW, Granton J, Watpool I, Stewart DJ, McIntyre LA, Mei SHJ; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.

Crit Care Med. 2019 Jul;47(7):918-925. doi: 10.1097/CCM.0000000000003657.

14.

Early May Be Better: Early Low-Dose Norepinephrine in Septic Shock.

Russell JA, Gordon AC, Walley KR.

Am J Respir Crit Care Med. 2019 May 1;199(9):1049-1051. doi: 10.1164/rccm.201901-0083ED. No abstract available.

15.

Genetic Polymorphisms in Sepsis and Cardiovascular Disease: Do Similar Risk Genes Suggest Similar Drug Targets?

Nakada TA, Takahashi W, Nakada E, Shimada T, Russell JA, Walley KR.

Chest. 2019 Jun;155(6):1260-1271. doi: 10.1016/j.chest.2019.01.003. Epub 2019 Jan 17. Review.

PMID:
30660782
16.

Vasopressin versus norepinephrine in septic shock: a propensity score matched efficiency retrospective cohort study in the VASST coordinating center hospital.

Russell JA, Wellman H, Walley KR.

J Intensive Care. 2018 Nov 16;6:73. doi: 10.1186/s40560-018-0344-2. eCollection 2018.

17.

Impact of PCSK9 loss-of-function genotype on 1-year mortality and recurrent infection in sepsis survivors.

Genga KR, Lo C, Cirstea MS, Leitao Filho FS, Walley KR, Russell JA, Linder A, Francis GA, Boyd JH.

EBioMedicine. 2018 Dec;38:257-264. doi: 10.1016/j.ebiom.2018.11.032. Epub 2018 Nov 23.

18.

CETP genetic variant rs1800777 (allele A) is associated with abnormally low HDL-C levels and increased risk of AKI during sepsis.

Genga KR, Trinder M, Kong HJ, Li X, Leung AKK, Shimada T, Walley KR, Russell JA, Francis GA, Brunham LR, Boyd JH.

Sci Rep. 2018 Nov 13;8(1):16764. doi: 10.1038/s41598-018-35261-2.

19.

Low Low-Density Lipoprotein Levels Are Associated With, But Do Not Causally Contribute to, Increased Mortality in Sepsis.

Walley KR, Boyd JH, Kong HJ, Russell JA.

Crit Care Med. 2019 Mar;47(3):463-466. doi: 10.1097/CCM.0000000000003551.

PMID:
30394916
20.

Development and internal validation of the multivariable CIPHER (Collaborative Integrated Pregnancy High-dependency Estimate of Risk) clinical risk prediction model.

Payne BA, Ryan H, Bone J, Magee LA, Aarvold AB, Mark Ansermino J, Bhutta ZA, Bowen M, Guilherme Cecatti J, Chazotte C, Crozier T, de Pont AJM, Demirkiran O, Duan T, Kallen M, Ganzevoort W, Geary M, Goffman D, Hutcheon JA, Joseph KS, Lapinsky SE, Lataifeh I, Li J, Liskonova S, Hamel EM, McAuliffe FM, O'Herlihy C, Mol BWJ, Seaward PGR, Tadros R, Togal T, Qureshi R, Vivian Ukah U, Vasquez D, Wallace E, Yong P, Zhou V, Walley KR, von Dadelszen P; CIPHER Group.

Crit Care. 2018 Oct 30;22(1):278. doi: 10.1186/s13054-018-2215-6.

21.

Identification of Acute Kidney Injury Subphenotypes with Differing Molecular Signatures and Responses to Vasopressin Therapy.

Bhatraju PK, Zelnick LR, Herting J, Katz R, Mikacenic C, Kosamo S, Morrell ED, Robinson-Cohen C, Calfee CS, Christie JD, Liu KD, Matthay MA, Hahn WO, Dmyterko V, Slivinski NSJ, Russell JA, Walley KR, Christiani DC, Liles WC, Himmelfarb J, Wurfel MM.

Am J Respir Crit Care Med. 2019 Apr 1;199(7):863-872. doi: 10.1164/rccm.201807-1346OC.

PMID:
30334632
22.

Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis.

Trinder M, Genga KR, Kong HJ, Blauw LL, Lo C, Li X, Cirstea M, Wang Y, Rensen PCN, Russell JA, Walley KR, Boyd JH, Brunham LR.

Am J Respir Crit Care Med. 2019 Apr 1;199(7):854-862. doi: 10.1164/rccm.201806-1157OC.

PMID:
30321485
23.

The Impact of Chronic Ozone and Particulate Air Pollution on Mortality in Patients With Sepsis Across the United States.

Rush B, Wiskar K, Fruhstorfer C, Celi LA, Walley KR.

J Intensive Care Med. 2018 Oct 7:885066618804497. doi: 10.1177/0885066618804497. [Epub ahead of print]

PMID:
30295138
24.

Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial.

von Dadelszen P, Magee LA, Benton SJ, Hu Y, Ansermino JM, Carleton B, Carter C, Douglas MJ, Janssen PA, Lee SK, Leung PCK, Li J, MacNab Y, Payne BA, Peng G, Rodger M, Skoll MA, Synnes A, Walley KR, Russell JA.

Pregnancy Hypertens. 2018 Jul;13:121-126. doi: 10.1016/j.preghy.2018.05.009. Epub 2018 May 28.

25.

The Emerging Role of Palliative Care in the Management of Canadians With Heart Failure.

Rush B, Walley KR.

Can J Cardiol. 2018 Sep;34(9):1114-1115. doi: 10.1016/j.cjca.2018.06.018. Epub 2018 Jul 11. No abstract available.

PMID:
30093302
26.

Sepsis in pregnancy and the puerperium.

Burlinson CEG, Sirounis D, Walley KR, Chau A.

Int J Obstet Anesth. 2018 Nov;36:96-107. doi: 10.1016/j.ijoa.2018.04.010. Epub 2018 Jun 18. Review.

PMID:
29921485
27.

Sepsis-induced myocardial dysfunction.

Walley KR.

Curr Opin Crit Care. 2018 Aug;24(4):292-299. doi: 10.1097/MCC.0000000000000507. Review.

PMID:
29846206
28.

The Understanding and Management of Organism Toxicity in Septic Shock.

Genga KR, Shimada T, Boyd JH, Walley KR, Russell JA.

J Innate Immun. 2018;10(5-6):502-514. doi: 10.1159/000487818. Epub 2018 May 15. Review.

29.

The design and rationale of SAVE BC: The Study to Avoid CardioVascular Events in British Columbia.

Brunham LR, Lynch K, English A, Sutherland R, Weng J, Cho R, Wong GC, Anis AH, Francis GA, Khan NA, McManus B, Wood D, Walley KR, Leipsic J, Humphries KH, Hoens A, Krahn AD, John Mancini GB, Pimstone S.

Clin Cardiol. 2018 Jul;41(7):888-895. doi: 10.1002/clc.22959. Epub 2018 Jun 11.

30.

Using multiple 'omics strategies for novel therapies in sepsis.

Russell JA, Spronk P, Walley KR.

Intensive Care Med. 2018 Apr;44(4):509-511. doi: 10.1007/s00134-018-5122-z. Epub 2018 Mar 15. No abstract available.

PMID:
29546534
31.

Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis.

Lee JGH, Genga KR, Pisitsak C, Boyd JH, Leung AKK, Russell JA, Walley KR.

Crit Care. 2018 Mar 6;22(1):58. doi: 10.1186/s13054-018-1985-1.

32.

Is Heparin-Binding Protein Inhibition a Mechanism of Albumin's Efficacy in Human Septic Shock?

Fisher J, Linder A, Bentzer P, Boyd J, Kong HJ, Lee T, Walley KR, Russell JA.

Crit Care Med. 2018 May;46(5):e364-e374. doi: 10.1097/CCM.0000000000002996.

PMID:
29406419
33.

Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis.

Annane D, Mira JP, Ware LB, Gordon AC, Hinds CJ, Christiani DC, Sevransky J, Barnes K, Buchman TG, Heagerty PJ, Balshaw R, Lesnikova N, de Nobrega K, Wellman HF, Neira M, Mancini ADJ, Walley KR, Russell JA.

Ann Intensive Care. 2018 Jan 31;8(1):16. doi: 10.1186/s13613-018-0353-2.

34.

The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock.

Nakada TA, Wacharasint P, Russell JA, Boyd JH, Nakada E, Thair SA, Shimada T, Walley KR.

J Innate Immun. 2018;10(3):181-188. doi: 10.1159/000486104. Epub 2018 Jan 16.

35.

Mitigating Microvascular Leak during Fluid Resuscitation of Hemorrhagic Shock.

Walley KR.

Anesthesiology. 2018 Feb;128(2):252-253. doi: 10.1097/ALN.0000000000002008. No abstract available.

PMID:
29232207
36.

Tamponade: Hemodynamic and Echocardiographic Diagnosis.

Kearns MJ, Walley KR.

Chest. 2018 May;153(5):1266-1275. doi: 10.1016/j.chest.2017.11.003. Epub 2017 Nov 11. Review.

PMID:
29137910
37.

Outcomes of Ventilated Patients With Sepsis Who Undergo Interhospital Transfer: A Nationwide Linked Analysis.

Rush B, Tyler PD, Stone DJ, Geisler BP, Walley KR, Celi LA.

Crit Care Med. 2018 Jan;46(1):e81-e86. doi: 10.1097/CCM.0000000000002777.

38.

Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial.

McIntyre LA, Stewart DJ, Mei SHJ, Courtman D, Watpool I, Granton J, Marshall J, Dos Santos C, Walley KR, Winston BW, Schlosser K, Fergusson DA; Canadian Critical Care Trials Group; Canadian Critical Care Translational Biology Group.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):337-347. doi: 10.1164/rccm.201705-1006OC.

PMID:
28960096
39.

Reply.

Rush B, Walley KR, Celi LA, Rajoriya N, Brahmania M.

Hepatology. 2019 Feb;69(2):920-921. doi: 10.1002/hep.29534. No abstract available.

PMID:
28922468
40.

Patterns of Palliative Care Referral in Patients Admitted With Heart Failure Requiring Mechanical Ventilation.

Wiskar KJ, Celi LA, McDermid RC, Walley KR, Russell JA, Boyd JH, Rush B.

Am J Hosp Palliat Care. 2018 Apr;35(4):620-626. doi: 10.1177/1049909117727455. Epub 2017 Aug 22.

PMID:
28826226
41.

Inpatient palliative care referral and 9-month hospital readmission in patients with congestive heart failure: a linked nationwide analysis.

Wiskar K, Celi LA, Walley KR, Fruhstorfer C, Rush B.

J Intern Med. 2017 Nov;282(5):445-451. doi: 10.1111/joim.12657. Epub 2017 Sep 15.

42.

Palliative care access for hospitalized patients with end-stage liver disease across the United States.

Rush B, Walley KR, Celi LA, Rajoriya N, Brahmania M.

Hepatology. 2017 Nov;66(5):1585-1591. doi: 10.1002/hep.29297. Epub 2017 Sep 26.

PMID:
28660622
43.

Validating the Performance of the Modified Early Obstetric Warning System Multivariable Model to Predict Maternal Intensive Care Unit Admission.

Ryan HM, Jones MA, Payne BA, Sharma S, Hutfield AM, Lee T, Ukah UV, Walley KR, Magee LA, von Dadelszen P.

J Obstet Gynaecol Can. 2017 Sep;39(9):728-733.e3. doi: 10.1016/j.jogc.2017.01.028. Epub 2017 May 26.

44.

Erratum to: Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine.

Mehta S, Granton J, Gordon AC, Cook DJ, Lapinsky S, Newton G, Bandayrel K, Little A, Siau C, Ayers D, Singer J, Lee TCK, Walley KR, Storms M, Cooper DJ, Holmes CL, Hebert P, Presneill J, Russell JA; Vasopressin and Septic Shock Trial (VASST) Investigators.

Crit Care. 2017 May 4;21(1):98. doi: 10.1186/s13054-017-1680-7. No abstract available.

45.

Association of Household Income Level and In-Hospital Mortality in Patients With Sepsis: A Nationwide Retrospective Cohort Analysis.

Rush B, Wiskar K, Celi LA, Walley KR, Russell JA, McDermid RC, Boyd JH.

J Intensive Care Med. 2018 Oct;33(10):551-556. doi: 10.1177/0885066617703338. Epub 2017 Apr 7.

46.

The Septic Shock 3.0 Definition and Trials: A Vasopressin and Septic Shock Trial Experience.

Russell JA, Lee T, Singer J, Boyd JH, Walley KR; Vasopressin and Septic Shock Trial (VASST) Group.

Crit Care Med. 2017 Jun;45(6):940-948. doi: 10.1097/CCM.0000000000002323.

PMID:
28333757
47.

Heparin-Binding Protein (HBP): A Causative Marker and Potential Target for Heparin Treatment of Human Sepsis-Induced Acute Kidney Injury.

Fisher J, Russell JA, Bentzer P, Parsons D, Secchia S, Mörgelin M, Walley KR, Boyd JH, Linder A.

Shock. 2017 Sep;48(3):313-320. doi: 10.1097/SHK.0000000000000862.

PMID:
28319494
48.

Two-year follow-up of patients with septic shock presenting with low HDL: the effect upon acute kidney injury, death and estimated glomerular filtration rate.

Roveran Genga K, Lo C, Cirstea M, Zhou G, Walley KR, Russell JA, Levin A, Boyd JH.

J Intern Med. 2017 May;281(5):518-529. doi: 10.1111/joim.12601. Epub 2017 Mar 19.

49.

New Approaches to Modifying Inotropy in Sepsis-Induced Myocardial Dysfunction.

Walley KR.

Crit Care Med. 2017 Apr;45(4):754-756. doi: 10.1097/CCM.0000000000002126. No abstract available.

PMID:
28291104
50.

The authors reply.

Pisitsak C, Walley KR.

Crit Care Med. 2017 Mar;45(3):e332-e333. doi: 10.1097/CCM.0000000000002221. No abstract available.

PMID:
28212234

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