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Items: 1 to 50 of 214

1.

Synthesis of 1,4-Thiazepane-Based Curcuminoids with Promising Anticancer Activity.

Theppawong A, Van de Walle T, Van Hecke K, Grootaert C, Van Camp J, D'hooghe M.

Chemistry. 2019 Sep 25;25(54):12583-12600. doi: 10.1002/chem.201902549. Epub 2019 Sep 3.

PMID:
31283064
2.

HIV positive status disclosure and associated factor among HIV infected children in pediatric ART clinics in Gondar town public health facilities, North West Ethiopia, 2018.

Abegaz BF, Walle TA, Tilahun AD.

J Infect Public Health. 2019 Jun 15. pii: S1876-0341(19)30186-8. doi: 10.1016/j.jiph.2019.05.018. [Epub ahead of print]

3.
4.

Synthesis of Non-Symmetrical Nitrogen-Containing Curcuminoids in the Pursuit of New Anticancer Candidates.

Theppawong A, Van de Walle T, Grootaert C, Van Hecke K, Catry N, Desmet T, Van Camp J, D'hooghe M.

ChemistryOpen. 2019 Feb 27;8(2):236-247. doi: 10.1002/open.201800287. eCollection 2019 Feb.

5.

Synthesis of Novel Aza-aromatic Curcuminoids with Improved Biological Activities towards Various Cancer Cell Lines.

Theppawong A, Van de Walle T, Grootaert C, Bultinck M, Desmet T, Van Camp J, D'hooghe M.

ChemistryOpen. 2018 May 25;7(5):381-392. doi: 10.1002/open.201800029. eCollection 2018 May.

6.

Radiation effects on antitumor immune responses: current perspectives and challenges.

Walle T, Martinez Monge R, Cerwenka A, Ajona D, Melero I, Lecanda F.

Ther Adv Med Oncol. 2018 Jan 18;10:1758834017742575. doi: 10.1177/1758834017742575. eCollection 2018. Review.

7.

Continuous Subcutaneous Insulin Infusion During Pregnancy in Women with Complicated Type 1 Diabetes Is Associated with Better Glycemic Control but Not with Improvement in Pregnancy Outcomes.

Kekäläinen P, Juuti M, Walle T, Laatikainen T.

Diabetes Technol Ther. 2016 Mar;18(3):144-50. doi: 10.1089/dia.2015.0165. Epub 2015 Oct 26.

PMID:
26502287
8.

Pregnancy planning in type 1 diabetic women improves glycemic control and pregnancy outcomes.

Kekäläinen P, Juuti M, Walle T, Laatikainen T.

J Matern Fetal Neonatal Med. 2016;29(14):2252-8. doi: 10.3109/14767058.2015.1081888. Epub 2015 Sep 11.

PMID:
26364952
9.

What is new for an old molecule? Systematic review and recommendations on the use of resveratrol.

Vang O, Ahmad N, Baile CA, Baur JA, Brown K, Csiszar A, Das DK, Delmas D, Gottfried C, Lin HY, Ma QY, Mukhopadhyay P, Nalini N, Pezzuto JM, Richard T, Shukla Y, Surh YJ, Szekeres T, Szkudelski T, Walle T, Wu JM.

PLoS One. 2011;6(6):e19881. doi: 10.1371/journal.pone.0019881. Epub 2011 Jun 16. Review.

10.

Bioavailability of resveratrol.

Walle T.

Ann N Y Acad Sci. 2011 Jan;1215:9-15. doi: 10.1111/j.1749-6632.2010.05842.x. Review.

PMID:
21261636
11.

Methylation of dietary flavones increases their metabolic stability and chemopreventive effects.

Walle T.

Int J Mol Sci. 2009 Nov 18;10(11):5002-19. doi: 10.3390/ijms10115002. Review.

12.

Methylation of dietary flavones greatly improves their hepatic metabolic stability and intestinal absorption.

Walle T.

Mol Pharm. 2007 Nov-Dec;4(6):826-32. Epub 2007 Oct 25. Review.

PMID:
17958394
13.

Cytotoxic effects of the dietary flavones chrysin and apigenin in a normal trout liver cell line.

Tsuji PA, Walle T.

Chem Biol Interact. 2008 Jan 10;171(1):37-44. Epub 2007 Aug 17.

14.

Bioavailable flavonoids: cytochrome P450-mediated metabolism of methoxyflavones.

Walle UK, Walle T.

Drug Metab Dispos. 2007 Nov;35(11):1985-9. Epub 2007 Aug 20.

PMID:
17709371
15.

Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells.

Walle T, Walle UK.

J Pharm Pharmacol. 2007 Jun;59(6):857-62.

PMID:
17637178
16.

Aromatase inhibition by bioavailable methylated flavones.

Ta N, Walle T.

J Steroid Biochem Mol Biol. 2007 Oct;107(1-2):127-9. Epub 2007 Jun 6.

17.
18.

Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?

Walle T.

Semin Cancer Biol. 2007 Oct;17(5):354-62. Epub 2007 May 13. Review.

19.

Improving metabolic stability of cancer chemoprotective polyphenols.

Walle T, Wen X, Walle UK.

Expert Opin Drug Metab Toxicol. 2007 Jun;3(3):379-88. Review.

PMID:
17539745
20.

Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones.

Walle T, Ta N, Kawamori T, Wen X, Tsuji PA, Walle UK.

Biochem Pharmacol. 2007 May 1;73(9):1288-96. Epub 2006 Dec 28.

21.
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23.

Methylated flavonoids have greatly improved intestinal absorption and metabolic stability.

Wen X, Walle T.

Drug Metab Dispos. 2006 Oct;34(10):1786-92. Epub 2006 Jul 25.

PMID:
16868069
24.

Methylation protects dietary flavonoids from rapid hepatic metabolism.

Wen X, Walle T.

Xenobiotica. 2006 May;36(5):387-97.

PMID:
16854778
25.

Quercetin induces necrosis and apoptosis in SCC-9 oral cancer cells.

Haghiac M, Walle T.

Nutr Cancer. 2005;53(2):220-31.

PMID:
16573383
26.

Cytochrome P450 1B1, a novel chemopreventive target for benzo[a]pyrene-initiated human esophageal cancer.

Wen X, Walle T.

Cancer Lett. 2007 Feb 8;246(1-2):109-14. Epub 2006 Mar 13.

PMID:
16530937
27.
28.

Benzo[A]pyrene-induced oral carcinogenesis and chemoprevention: studies in bioengineered human tissue.

Walle T, Walle UK, Sedmera D, Klausner M.

Drug Metab Dispos. 2006 Mar;34(3):346-50. Epub 2005 Dec 28.

PMID:
16381670
29.

Formation of transient covalent protein and DNA adducts by quercetin in cells with and without oxidative enzyme activity.

van der Woude H, Alink GM, van Rossum BE, Walle K, van Steeg H, Walle T, Rietjens IM.

Chem Res Toxicol. 2005 Dec;18(12):1907-16.

PMID:
16359181
30.

Flavonoid glycosides inhibit oral cancer cell proliferation--role of cellular uptake and hydrolysis to the aglycones.

Browning AM, Walle UK, Walle T.

J Pharm Pharmacol. 2005 Aug;57(8):1037-42.

PMID:
16102260
31.

Anti-nucleosome antibodies in the diagnosis of systemic lupus erythematosus.

Julkunen H, Salonen EM, Walle TK, Miettinen A.

Scand J Rheumatol. 2005 Mar-Apr;34(2):122-4.

PMID:
16095007
32.
33.

S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytes.

McMillan JM, Walle UK, Walle T.

J Pharm Pharmacol. 2005 May;57(5):599-605.

PMID:
15901349
34.

Covalent binding of the flavonoid quercetin to human serum albumin.

Kaldas MI, Walle UK, van der Woude H, McMillan JM, Walle T.

J Agric Food Chem. 2005 May 18;53(10):4194-7.

PMID:
15884859
35.

The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1.

Whitley AC, Sweet DH, Walle T.

Drug Metab Dispos. 2005 Aug;33(8):1097-100. Epub 2005 May 3.

PMID:
15870380
36.

Cellular uptake of a radiolabelled analogue of neurotensin in the Caco-2 cell model.

Hadden MK, Walle T, Dix TA.

J Pharm Pharmacol. 2005 Mar;57(3):327-33.

PMID:
15807988
37.

5,7-Dimethoxyflavone downregulates CYP1A1 expression and benzo[a]pyrene-induced DNA binding in Hep G2 cells.

Wen X, Walle UK, Walle T.

Carcinogenesis. 2005 Apr;26(4):803-9. Epub 2005 Jan 20.

PMID:
15661813
38.

Flavonoid glucosides are hydrolyzed and thus activated in the oral cavity in humans.

Walle T, Browning AM, Steed LL, Reed SG, Walle UK.

J Nutr. 2005 Jan;135(1):48-52.

PMID:
15623831
39.
40.

High absorption but very low bioavailability of oral resveratrol in humans.

Walle T, Hsieh F, DeLegge MH, Oatis JE Jr, Walle UK.

Drug Metab Dispos. 2004 Dec;32(12):1377-82. Epub 2004 Aug 27.

PMID:
15333514
41.

Relationship of maternal autoimmune response to clinical manifestations in children with congenital complete heart block.

Eronen M, Miettinen A, Walle TK, Chan EK, Julkunen H.

Acta Paediatr. 2004 Jun;93(6):803-9.

PMID:
15244231
42.

Absorption and metabolism of flavonoids.

Walle T.

Free Radic Biol Med. 2004 Apr 1;36(7):829-37. Review.

PMID:
15019968
43.

Autoimmune response in mothers of children with congenital and postnatally diagnosed isolated heart block: a population based study.

Julkunen H, Miettinen A, Walle TK, Chan EK, Eronen M.

J Rheumatol. 2004 Jan;31(1):183-9.

PMID:
14705240
45.

Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2.

Vaidyanathan JB, Walle T.

J Pharmacol Exp Ther. 2003 Nov;307(2):745-52. Epub 2003 Sep 11.

PMID:
12970388
46.

Intestinal epithelial cell accumulation of the cancer preventive polyphenol ellagic acid--extensive binding to protein and DNA.

Whitley AC, Stoner GD, Darby MV, Walle T.

Biochem Pharmacol. 2003 Sep 15;66(6):907-15.

PMID:
12963477
47.

Evidence of covalent binding of the dietary flavonoid quercetin to DNA and protein in human intestinal and hepatic cells.

Walle T, Vincent TS, Walle UK.

Biochem Pharmacol. 2003 May 15;65(10):1603-10.

PMID:
12754096
48.

Resveratrol transport and metabolism by human intestinal Caco-2 cells.

Kaldas MI, Walle UK, Walle T.

J Pharm Pharmacol. 2003 Mar;55(3):307-12.

PMID:
12724035
49.

Familial and sporadic inflammatory bowel disease: comparison of clinical features and serological markers in a genetically homogeneous population.

Halme L, Turunen U, Heliö T, Paavola P, Walle T, Miettinen A, Järvinen H, Kontula K, Färkkilä M.

Scand J Gastroenterol. 2002 Jun;37(6):692-8.

PMID:
12126248
50.

Glucuronidation and sulfation of the tea flavonoid (-)-epicatechin by the human and rat enzymes.

Vaidyanathan JB, Walle T.

Drug Metab Dispos. 2002 Aug;30(8):897-903.

PMID:
12124307

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