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Items: 36

1.

Supplementation with Bovine Milk or Soy Beverages Recovers Bone Mineralization in Young Growing Rats Fed an Insufficient Diet, in Contrast to an Almond Beverage.

Cakebread JA, Wallace OAM, Kruger MC, Vickers MH, Hodgkinson AJ.

Curr Dev Nutr. 2019 Oct 12;3(11):nzz115. doi: 10.1093/cdn/nzz115. eCollection 2019 Nov.

PMID:
31720556
2.

A survey of core replacements in indole-based HIV-1 attachment inhibitors.

Wang T, Wallace OB, Zhang Z, Fang H, Yang Z, Robinson BA, Spicer TP, Gong YF, Blair WS, Shi PY, Lin PF, Deshpande M, Meanwell NA, Kadow JF.

Bioorg Med Chem Lett. 2019 Jun 1;29(11):1423-1429. doi: 10.1016/j.bmcl.2019.03.018. Epub 2019 Mar 28.

PMID:
30940396
3.

Discovery of a ZIP7 inhibitor from a Notch pathway screen.

Nolin E, Gans S, Llamas L, Bandyopadhyay S, Brittain SM, Bernasconi-Elias P, Carter KP, Loureiro JJ, Thomas JR, Schirle M, Yang Y, Guo N, Roma G, Schuierer S, Beibel M, Lindeman A, Sigoillot F, Chen A, Xie KX, Ho S, Reece-Hoyes J, Weihofen WA, Tyskiewicz K, Hoepfner D, McDonald RI, Guthrie N, Dogra A, Guo H, Shao J, Ding J, Canham SM, Boynton G, George EL, Kang ZB, Antczak C, Porter JA, Wallace O, Tallarico JA, Palmer AE, Jenkins JL, Jain RK, Bushell SM, Fryer CJ.

Nat Chem Biol. 2019 Feb;15(2):179-188. doi: 10.1038/s41589-018-0200-7. Epub 2019 Jan 14.

PMID:
30643281
4.

Gastric digestion of cow and goat milk: Peptides derived from simulated conditions of infant digestion.

Hodgkinson AJ, Wallace OAM, Smolenski G, Prosser CG.

Food Chem. 2019 Mar 15;276:619-625. doi: 10.1016/j.foodchem.2018.10.065. Epub 2018 Oct 12.

PMID:
30409640
5.

Bovine milk derived skimmed milk powder and whey protein concentrate modulates Citrobacter rodentium shedding in the mouse intestinal tract.

Cakebread J, Hodgkinson A, Wallace O, Callaghan M, Hurford D, Wieliczko R, Harris P, Haigh B.

PeerJ. 2018 Jul 27;6:e5359. doi: 10.7717/peerj.5359. eCollection 2018.

6.

Gastric digestion of cow and goat milk: Impact of infant and young child in vitro digestion conditions.

Hodgkinson AJ, Wallace OAM, Boggs I, Broadhurst M, Prosser CG.

Food Chem. 2018 Apr 15;245:275-281. doi: 10.1016/j.foodchem.2017.10.028. Epub 2017 Oct 7.

PMID:
29287371
7.

Effect of the dietary delivery matrix on vitamin D3 bioavailability and bone mineralisation in vitamin-D3-deficient growing male rats.

Hodgkinson AJ, Wallace OAM, Kruger MC, Prosser CG.

Br J Nutr. 2018 Jan;119(2):143-152. doi: 10.1017/S0007114517003518. Epub 2017 Dec 22.

PMID:
29268806
8.

An analysis of the attrition of drug candidates from four major pharmaceutical companies.

Waring MJ, Arrowsmith J, Leach AR, Leeson PD, Mandrell S, Owen RM, Pairaudeau G, Pennie WD, Pickett SD, Wang J, Wallace O, Weir A.

Nat Rev Drug Discov. 2015 Jul;14(7):475-86. doi: 10.1038/nrd4609. Epub 2015 Jun 19. Review.

PMID:
26091267
9.

Transfer of intestinal bacterial components to mammary secretions in the cow.

Young W, Hine BC, Wallace OA, Callaghan M, Bibiloni R.

PeerJ. 2015 Apr 23;3:e888. doi: 10.7717/peerj.888. eCollection 2015.

10.

Canine distemper virus neutralization activity is low in human serum and it is sensitive to an amino acid substitution in the hemagglutinin protein.

Zhang X, Wallace OL, Domi A, Wright KJ, Driscoll J, Anzala O, Sanders EJ, Kamali A, Karita E, Allen S, Fast P, Gilmour J, Price MA, Parks CL.

Virology. 2015 Aug;482:218-24. doi: 10.1016/j.virol.2015.03.035. Epub 2015 Apr 14.

11.

Development of a duplex real-time RT-qPCR assay to monitor genome replication, gene expression and gene insert stability during in vivo replication of a prototype live attenuated canine distemper virus vector encoding SIV gag.

Coleman JW, Wright KJ, Wallace OL, Sharma P, Arendt H, Martinez J, DeStefano J, Zamb TP, Zhang X, Parks CL.

J Virol Methods. 2015 Mar;213:26-37. doi: 10.1016/j.jviromet.2014.11.015. Epub 2014 Dec 5.

PMID:
25486083
12.

Membrane-bound SIV envelope trimers are immunogenic in ferrets after intranasal vaccination with a replication-competent canine distemper virus vector.

Zhang X, Wallace O, Wright KJ, Backer M, Coleman JW, Koehnke R, Frenk E, Domi A, Chiuchiolo MJ, DeStefano J, Narpala S, Powell R, Morrow G, Boggiano C, Zamb TJ, Richter King C, Parks CL.

Virology. 2013 Nov;446(1-2):25-36. doi: 10.1016/j.virol.2013.07.012. Epub 2013 Aug 9. Erratum in: Virology. 2014 Feb;450-451:371.

13.

An in vitro model for the morphogenesis of hair follicle dermal papillae.

Rufaut NW, Nixon AJ, Goldthorpe NT, Wallace OA, Pearson AJ, Sinclair RD.

J Invest Dermatol. 2013 Aug;133(8):2085-8. doi: 10.1038/jid.2013.132. Epub 2013 Mar 14. No abstract available.

14.

The Germinative Epithelium of Sheep Vibrissae and Wool Follicles has Extensive Proliferative Potential but is Dependent on the Dermal Papilla.

Rufaut NW, Goldthorpe NT, Craven AJ, Wallace OA, Wildermoth JE, Nixon AJ.

Int J Trichology. 2012 Apr;4(2):75-82. doi: 10.4103/0974-7753.96908.

15.

Annotation of sheep keratin intermediate filament genes and their patterns of expression.

Yu Z, Wildermoth JE, Wallace OA, Gordon SW, Maqbool NJ, Maclean PH, Nixon AJ, Pearson AJ.

Exp Dermatol. 2011 Jul;20(7):582-8. doi: 10.1111/j.1600-0625.2011.01274.x. Epub 2011 May 10.

PMID:
21554405
16.

Identification of amide bioisosteres of triazole oxytocin antagonists.

Brown A, Ellis D, Wallace O, Ralph M.

Bioorg Med Chem Lett. 2010 Apr 1;20(7):2224-8. doi: 10.1016/j.bmcl.2010.02.018. Epub 2010 Feb 8.

PMID:
20189387
17.

Identification of a urea bioisostere of a triazole oxytocin antagonist.

Brown A, Ellis D, Wallace O, Ralph M.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1851-3. doi: 10.1016/j.bmcl.2010.01.143. Epub 2010 Feb 2.

PMID:
20172721
18.

Inhibitors of HIV-1 attachment. Part 3: A preliminary survey of the effect of structural variation of the benzamide moiety on antiviral activity.

Meanwell NA, Wallace OB, Wang H, Deshpande M, Pearce BC, Trehan A, Yeung KS, Qiu Z, Wright JJ, Robinson BA, Gong YF, Wang HG, Spicer TP, Blair WS, Shi PY, Lin PF.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5136-9. doi: 10.1016/j.bmcl.2009.07.027. Epub 2009 Jul 10. Erratum in: Bioorg Med Chem Lett. 2010 Feb 15;20(4):1461. Spicer, Timothy P [added].

PMID:
19632112
19.

Inhibitors of HIV-1 attachment. Part 2: An initial survey of indole substitution patterns.

Meanwell NA, Wallace OB, Fang H, Wang H, Deshpande M, Wang T, Yin Z, Zhang Z, Pearce BC, James J, Yeung KS, Qiu Z, Kim Wright JJ, Yang Z, Zadjura L, Tweedie DL, Yeola S, Zhao F, Ranadive S, Robinson BA, Gong YF, Wang HG, Spicer TP, Blair WS, Shi PY, Colonno RJ, Lin PF.

Bioorg Med Chem Lett. 2009 Apr 1;19(7):1977-81. doi: 10.1016/j.bmcl.2009.02.040. Epub 2009 Feb 13. Erratum in: Bioorg Med Chem Lett. 2010 Feb 15;20(4):1460. Spicer, Timothy P [added].

PMID:
19251416
20.

Triazole oxytocin antagonists: identification of aryl ether replacements for a biaryl substituent.

Brown A, Brown L, Brown TB, Calabrese A, Ellis D, Puhalo N, Smith CR, Wallace O, Watson L.

Bioorg Med Chem Lett. 2008 Oct 1;18(19):5242-4. doi: 10.1016/j.bmcl.2008.08.066. Epub 2008 Aug 22.

PMID:
18778939
21.

Design and optimization of potent, selective antagonists of Oxytocin.

Brown A, Brown L, Ellis D, Puhalo N, Smith CR, Wallace O, Watson L.

Bioorg Med Chem Lett. 2008 Aug 1;18(15):4278-81. doi: 10.1016/j.bmcl.2008.06.098. Epub 2008 Jul 3.

PMID:
18639455
22.

N-(5-chloro-2-(hydroxymethyl)-N-alkyl-arylsulfonamides as gamma-secretase inhibitors.

Parker MF, Barten DM, Bergstrom CP, Bronson JJ, Corsa JA, Deshpande MS, Felsenstein KM, Guss VL, Hansel SB, Johnson G, Keavy DJ, Lau WY, Mock J, Prasad CV, Polson CT, Sloan CP, Smith DW, Wallace OB, Wang HH, Williams A, Zheng M.

Bioorg Med Chem Lett. 2007 Aug 15;17(16):4432-6. Epub 2007 Jun 10.

PMID:
17606371
23.

Structure-activity relationships of SERMs optimized for uterine antagonism and ovarian safety.

Richardson TI, Frank SA, Wang M, Clarke CA, Jones SA, Ying BP, Kohlman DT, Wallace OB, Shepherd TA, Dally RD, Palkowitz AD, Geiser AG, Bryant HU, Henck JW, Cohen IR, Rudmann DG, McCann DJ, Coutant DE, Oldham SW, Hummel CW, Fong KC, Hinklin R, Lewis G, Tian H, Dodge JA.

Bioorg Med Chem Lett. 2007 Jul 1;17(13):3544-9. Epub 2007 Apr 24.

PMID:
17482463
24.

Myogenic differentiation of dermal papilla cells from bovine skin.

Rufaut NW, Goldthorpe NT, Wildermoth JE, Wallace OA.

J Cell Physiol. 2006 Dec;209(3):959-66.

PMID:
16972246
25.

A selective estrogen receptor modulator for the treatment of hot flushes.

Wallace OB, Lauwers KS, Dodge JA, May SA, Calvin JR, Hinklin R, Bryant HU, Shetler PK, Adrian MD, Geiser AG, Sato M, Burris TP.

J Med Chem. 2006 Feb 9;49(3):843-6.

PMID:
16451049
26.

A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats.

Hummel CW, Geiser AG, Bryant HU, Cohen IR, Dally RD, Fong KC, Frank SA, Hinklin R, Jones SA, Lewis G, McCann DJ, Rudmann DG, Shepherd TA, Tian H, Wallace OB, Wang M, Wang Y, Dodge JA.

J Med Chem. 2005 Nov 3;48(22):6772-5.

PMID:
16250633
27.

A new selective estrogen receptor modulator with potent uterine antagonist activity, agonist activity in bone, and minimal ovarian stimulation.

Geiser AG, Hummel CW, Draper MW, Henck JW, Cohen IR, Rudmann DG, Donnelly KB, Adrian MD, Shepherd TA, Wallace OB, McCann DJ, Oldham SW, Bryant HU, Sato M, Dodge JA.

Endocrinology. 2005 Oct;146(10):4524-35. Epub 2005 Jul 7.

PMID:
16002528
28.

Benzothiophene and naphthalene derived constrained SERMs.

Wallace OB, Bryant HU, Shetler PK, Adrian MD, Geiser AG.

Bioorg Med Chem Lett. 2004 Oct 18;14(20):5103-6.

PMID:
15380208
29.

Hydroxytriamides as potent gamma-secretase inhibitors.

Prasad CV, Wallace OB, Noonan JW, Sloan CP, Lau W, Vig S, Parker MF, Smith DW, Hansel SB, Polson CT, Barten DM, Felsenstein KM, Roberts SB.

Bioorg Med Chem Lett. 2004 Apr 19;14(8):1917-21. Erratum in: Bioorg Med Chem Lett. 2004 Jun 21;14(12):3361.

PMID:
15050627
30.

Estrogen receptor modulators: relationships of ligand structure, receptor affinity and functional activity.

Wallace OB, Richardson TI, Dodge JA.

Curr Top Med Chem. 2003;3(14):1663-82. Review.

PMID:
14683521
31.

Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions.

Wang T, Zhang Z, Wallace OB, Deshpande M, Fang H, Yang Z, Zadjura LM, Tweedie DL, Huang S, Zhao F, Ranadive S, Robinson BS, Gong YF, Ricarrdi K, Spicer TP, Deminie C, Rose R, Wang HG, Blair WS, Shi PY, Lin PF, Colonno RJ, Meanwell NA.

J Med Chem. 2003 Sep 25;46(20):4236-9.

PMID:
13678401
32.

Tetrahydroquinoline-based selective estrogen receptor modulators (SERMs).

Wallace OB, Lauwers KS, Jones SA, Dodge JA.

Bioorg Med Chem Lett. 2003 Jun 2;13(11):1907-10.

PMID:
12749895
33.

Inhibitors of Abeta production: solid-phase synthesis and SAR of alpha-hydroxycarbonyl derivatives.

Wallace OB, Smith DW, Deshpande MS, Polson C, Felsenstein KM.

Bioorg Med Chem Lett. 2003 Mar 24;13(6):1203-6.

PMID:
12643944
34.

Corrigendum.

Blair WS, Lin PF, Meanwell NA, Wallace OB.

Drug Discov Today. 2000 Jul;5(7):285. No abstract available.

PMID:
10856910
35.

HIV-1 entry - an expanding portal for drug discovery.

Blair WS, Lin PF, Meanwell NA, Wallace OB.

Drug Discov Today. 2000 May;5(5):183-194.

PMID:
10790262
36.

Lc-11 (Hunt B, Jones) as a mutually exclusive specificity to Lc-1,2, and 3 in the main human leukocyte group.

Walford RL, Wallace O, Shanbrom E, Troup GM.

Vox Sang. 1968;15(5):338-44. No abstract available.

PMID:
5699690

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