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Prolonged PSA stabilization and overall survival following sipuleucel-T monotherapy in metastatic castration-resistant prostate cancer patients.

Holl EK, McNamara MA, Healy P, Anand M, Concepcion RS, Breland CD, Dumbudze I, Tutrone R, Shore N, Armstrong AJ, Harrison M, Wallace JA, Wu Y, George DJ.

Prostate Cancer Prostatic Dis. 2019 Apr 12. doi: 10.1038/s41391-019-0144-3. [Epub ahead of print]


Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.

Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC.

Oncogene. 2017 Nov 23;36(47):6658. doi: 10.1038/onc.2017.347. Epub 2017 Oct 16.


Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade.

Huffaker TB, Lee SH, Tang WW, Wallace JA, Alexander M, Runtsch MC, Larsen DK, Thompson J, Ramstead AG, Voth WP, Hu R, Round JL, Williams MA, O'Connell RM.

J Biol Chem. 2017 Nov 10;292(45):18530-18541. doi: 10.1074/jbc.M117.808121. Epub 2017 Sep 14.


Pasteurella multocida Bacteremia and Peritonitis in a Patient With Cirrhosis: A Life-Threatening Case From a Prick of a Cactus.

Wallace JA, Hussain J, Unzueta A, Morelli G.

J Investig Med High Impact Case Rep. 2017 Aug 30;5(3):2324709617726103. doi: 10.1177/2324709617726103. eCollection 2017 Jul-Sep.


Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes.

Seguin A, Takahashi-Makise N, Yien YY, Huston NC, Whitman JC, Musso G, Wallace JA, Bradley T, Bergonia HA, Kafina MD, Matsumoto M, Igarashi K, Phillips JD, Paw BH, Kaplan J, Ward DM.

J Biol Chem. 2017 Sep 29;292(39):16284-16299. doi: 10.1074/jbc.M117.797415. Epub 2017 Aug 14.


MicroRNAs and acute myeloid leukemia: therapeutic implications and emerging concepts.

Wallace JA, O'Connell RM.

Blood. 2017 Sep 14;130(11):1290-1301. doi: 10.1182/blood-2016-10-697698. Epub 2017 Jul 27. Review.


miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response.

Wallace JA, Kagele DA, Eiring AM, Kim CN, Hu R, Runtsch MC, Alexander M, Huffaker TB, Lee SH, Patel AB, Mosbruger TL, Voth WP, Rao DS, Miles RR, Round JL, Deininger MW, O'Connell RM.

Blood. 2017 Jun 8;129(23):3074-3086. doi: 10.1182/blood-2016-09-740209. Epub 2017 Apr 21.


Ventilatory and chemoreceptor responses to hypercapnia in neonatal rats chronically exposed to moderate hyperoxia.

Bavis RW, Li KY, DeAngelis KJ, March RJ, Wallace JA, Logan S, Putnam RW.

Respir Physiol Neurobiol. 2017 Mar;237:22-34. doi: 10.1016/j.resp.2016.12.008. Epub 2016 Dec 26.


Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.

Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC.

Oncogene. 2017 Apr 20;36(16):2297-2308. doi: 10.1038/onc.2016.383. Epub 2016 Oct 31. Erratum in: Oncogene. 2017 Oct 16;:.


All-Atom Continuous Constant pH Molecular Dynamics With Particle Mesh Ewald and Titratable Water.

Huang Y, Chen W, Wallace JA, Shen J.

J Chem Theory Comput. 2016 Nov 8;12(11):5411-5421. Epub 2016 Oct 24.


Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation.

Yost CC, Schwertz H, Cody MJ, Wallace JA, Campbell RA, Vieira-de-Abreu A, Araujo CV, Schubert S, Harris ES, Rowley JW, Rondina MT, Fulcher JM, Koening CL, Weyrich AS, Zimmerman GA.

J Clin Invest. 2016 Oct 3;126(10):3783-3798. doi: 10.1172/JCI83873. Epub 2016 Sep 6.


A Case of a Giant Borderline Phyllodes Tumor Early in Pregnancy Treated with Mastectomy and Immediate Breast Reconstruction.

Gentile LF, Gaillard WF, Wallace JA, Spiguel LR, Alizadeh L, Lentz A, Shaw C.

Breast J. 2016 Nov;22(6):683-687. doi: 10.1111/tbj.12663. Epub 2016 Aug 26.


Type 1 Diabetes--Reaping the Rewards of a Targeted Research Investment.

Fradkin JE, Wallace JA, Akolkar B, Rodgers GP.

Diabetes. 2016 Feb;65(2):307-13. doi: 10.2337/db15-1030.


Cry protein crystals: a novel platform for protein delivery.

Nair MS, Lee MM, Bonnegarde-Bernard A, Wallace JA, Dean DH, Ostrowski MC, Burry RW, Boyaka PN, Chan MK.

PLoS One. 2015 Jun 1;10(6):e0127669. doi: 10.1371/journal.pone.0127669. eCollection 2015.


Integrating health and safety in the workplace: how closely aligning health and safety strategies can yield measurable benefits.

Loeppke RR, Hohn T, Baase C, Bunn WB, Burton WN, Eisenberg BS, Ennis T, Fabius R, Hawkins RJ, Hudson TW, Hymel PA, Konicki D, Larson P, McLellan RK, Roberts MA, Usrey C, Wallace JA, Yarborough CM, Siuba J.

J Occup Environ Med. 2015 May;57(5):585-97. doi: 10.1097/JOM.0000000000000467.


Factors that predict increased catheter tip movement in left internal jugular vein implantable venous access ports upon standing.

Wallace JA, Afonso E, Yu H, Birchard K, Isaacson A.

J Vasc Access. 2015 May-Jun;16(3):223-6. doi: 10.5301/jva.5000331. Epub 2015 Jan 17.


Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain.

Dengler EC, Alberti LA, Bowman BN, Kerwin AA, Wilkerson JL, Moezzi DR, Limanovich E, Wallace JA, Milligan ED.

J Neuroinflammation. 2014 May 21;11:92. doi: 10.1186/1742-2094-11-92.


Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis.

Wallace JA, Pitarresi JR, Sharma N, Palettas M, Cuitiño MC, Sizemore ST, Yu L, Sanderlin A, Rosol TJ, Mehta KD, Sizemore GM, Ostrowski MC.

Front Oncol. 2014 Apr 23;4:87. doi: 10.3389/fonc.2014.00087. eCollection 2014.


Chagas disease: a proposal for testing policy for solid-organ transplant in the United States.

Wallace JA, Miller L, Beavis A, Baptista CA.

Prog Transplant. 2013 Sep;23(3):272-7. doi: 10.7182/pit2013712.


Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.

Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, Park M, Leone G, Ostrowski MC.

PLoS One. 2013 Aug 16;8(8):e71533. doi: 10.1371/journal.pone.0071533. eCollection 2013.


Introducing titratable water to all-atom molecular dynamics at constant pH.

Chen W, Wallace JA, Yue Z, Shen JK.

Biophys J. 2013 Aug 20;105(4):L15-7. doi: 10.1016/j.bpj.2013.06.036.


Treatment rationale and study design for a randomized, double-blind, placebo-controlled phase II study evaluating onartuzumab (MetMAb) in combination with bevacizumab plus mFOLFOX-6 in patients with previously untreated metastatic colorectal cancer.

Bendell JC, Ervin TJ, Gallinson D, Singh J, Wallace JA, Saleh MN, Vallone M, Phan SC, Hack SP.

Clin Colorectal Cancer. 2013 Sep;12(3):218-22. doi: 10.1016/j.clcc.2013.04.001. Epub 2013 Jun 27.


Biomedical research: paving a pathway to diabetes prevention.

Fradkin JE, Wallace JA, Rodgers GP.

Am J Prev Med. 2013 Apr;44(4 Suppl 4):S317-23. doi: 10.1016/j.amepre.2012.12.017. No abstract available.


Charge-leveling and proper treatment of long-range electrostatics in all-atom molecular dynamics at constant pH.

Wallace JA, Shen JK.

J Chem Phys. 2012 Nov 14;137(18):184105. doi: 10.1063/1.4766352.


The inhibitory activity of typified propolis against Enterococcus species.

Moncla BJ, Guevara PW, Wallace JA, Marcucci MC, Nor JE, Bretz WA.

Z Naturforsch C. 2012 May-Jun;67(5-6):249-56.


Unraveling A Trap-and-Trigger Mechanism in the pH-Sensitive Self-Assembly of Spider Silk Proteins.

Wallace JA, Shen JK.

J Phys Chem Lett. 2012 Mar 1;3(5):658-662. Epub 2012 Feb 15.


Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia.

Wilkerson JL, Gentry KR, Dengler EC, Wallace JA, Kerwin AA, Kuhn MN, Zvonok AM, Thakur GA, Makriyannis A, Milligan ED.

Brain Behav. 2012 Mar;2(2):155-77. doi: 10.1002/brb3.44.


Thermodynamic coupling of protonation and conformational equilibria in proteins: theory and simulation.

Shi C, Wallace JA, Shen JK.

Biophys J. 2012 Apr 4;102(7):1590-7. doi: 10.1016/j.bpj.2012.02.021. Epub 2012 Apr 3.


Intrathecal cannabilactone CB(2)R agonist, AM1710, controls pathological pain and restores basal cytokine levels.

Wilkerson JL, Gentry KR, Dengler EC, Wallace JA, Kerwin AA, Armijo LM, Kuhn MN, Thakur GA, Makriyannis A, Milligan ED.

Pain. 2012 May;153(5):1091-106. doi: 10.1016/j.pain.2012.02.015. Epub 2012 Mar 17.


Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.

Bronisz A, Godlewski J, Wallace JA, Merchant AS, Nowicki MO, Mathsyaraja H, Srinivasan R, Trimboli AJ, Martin CK, Li F, Yu L, Fernandez SA, Pécot T, Rosol TJ, Cory S, Hallett M, Park M, Piper MG, Marsh CB, Yee LD, Jimenez RE, Nuovo G, Lawler SE, Chiocca EA, Leone G, Ostrowski MC.

Nat Cell Biol. 2011 Dec 18;14(2):159-67. doi: 10.1038/ncb2396.


Comparison of results for commercially available microbiological media plates with results for standard bacteriologic testing of bovine milk.

Wallace JA, Bouchard É, DesCôteaux L, Messier S, DuTremblay D, Roy JP.

Am J Vet Res. 2011 Dec;72(12):1622-30. doi: 10.2460/ajvr.72.12.1622.


Simulating pH titration of a single surfactant in ionic and nonionic surfactant micelles.

Morrow BH, Wang Y, Wallace JA, Koenig PH, Shen JK.

J Phys Chem B. 2011 Dec 22;115(50):14980-90. doi: 10.1021/jp2062404. Epub 2011 Nov 22.


Continuous Constant pH Molecular Dynamics in Explicit Solvent with pH-Based Replica Exchange.

Wallace JA, Shen JK.

J Chem Theory Comput. 2011 Aug 9;7(8):2617-29. doi: 10.1021/ct200146j. Epub 2011 Jul 1.


Toward accurate prediction of pKa values for internal protein residues: the importance of conformational relaxation and desolvation energy.

Wallace JA, Wang Y, Shi C, Pastoor KJ, Nguyen BL, Xia K, Shen JK.

Proteins. 2011 Dec;79(12):3364-73. doi: 10.1002/prot.23080. Epub 2011 Jul 11.


Cancer in long-term care.

Korc-Grodzicki B, Wallace JA, Rodin MB, Bernacki RE.

Clin Geriatr Med. 2011 May;27(2):301-27. doi: 10.1016/j.cger.2011.03.011.


Dasatinib in previously treated metastatic colorectal cancer: a phase II trial of the University of Chicago Phase II Consortium.

Sharma MR, Wroblewski K, Polite BN, Knost JA, Wallace JA, Modi S, Sleckman BG, Taber D, Vokes EE, Stadler WM, Kindler HL.

Invest New Drugs. 2012 Jun;30(3):1211-5. doi: 10.1007/s10637-011-9681-x. Epub 2011 May 7.


Molecular dynamics simulations of ionic and nonionic surfactant micelles with a generalized Born implicit-solvent model.

Wang Y, Wallace JA, Koenig PH, Shen JK.

J Comput Chem. 2011 Aug;32(11):2348-58. doi: 10.1002/jcc.21813. Epub 2011 May 4.


Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution.

Wallace JA, Li F, Leone G, Ostrowski MC.

Cancer Res. 2011 Feb 15;71(4):1203-7. doi: 10.1158/0008-5472.CAN-10-3263. Epub 2011 Feb 8. Review.


Gemcitabine plus sorafenib in patients with advanced pancreatic cancer: a phase II trial of the University of Chicago Phase II Consortium.

Kindler HL, Wroblewski K, Wallace JA, Hall MJ, Locker G, Nattam S, Agamah E, Stadler WM, Vokes EE.

Invest New Drugs. 2012 Feb;30(1):382-6. doi: 10.1007/s10637-010-9526-z. Epub 2010 Aug 28.


Probing the strand orientation and registry alignment in the propagation of amyloid fibrils.

Wallace JA, Shen JK.

Biochemistry. 2010 Jun 29;49(25):5290-8. doi: 10.1021/bi100137y.


A macro-quality evaluation of DXA variables using whole dissection, ashing, and computer tomography in pigs.

Clarys JP, Scafoglieri A, Provyn S, Louis O, Wallace JA, De Mey J.

Obesity (Silver Spring). 2010 Aug;18(8):1477-85. doi: 10.1038/oby.2009.447. Epub 2009 Dec 17. No abstract available.


Pten in stromal fibroblasts suppresses mammary epithelial tumours.

Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, Gurcan MN, Weinstein MB, Barsky SH, Yee L, Rosol TJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski MC, Leone G.

Nature. 2009 Oct 22;461(7267):1084-91. doi: 10.1038/nature08486.


How well do skinfold equations predict percent body fat in elite soccer players?

Reilly T, George K, Marfell-Jones M, Scott M, Sutton L, Wallace JA.

Int J Sports Med. 2009 Aug;30(8):607-13. doi: 10.1055/s-0029-1202353. Epub 2009 Mar 19.


Predicting pKa values with continuous constant pH molecular dynamics.

Wallace JA, Shen JK.

Methods Enzymol. 2009;466:455-75. doi: 10.1016/S0076-6879(09)66019-5. Epub 2009 Nov 13.


Communication about cancer near the end of life.

Back AL, Anderson WG, Bunch L, Marr LA, Wallace JA, Yang HB, Arnold RM.

Cancer. 2008 Oct 1;113(7 Suppl):1897-910. doi: 10.1002/cncr.23653. Review.


We gather together: insulators and genome organization.

Wallace JA, Felsenfeld G.

Curr Opin Genet Dev. 2007 Oct;17(5):400-7. Epub 2007 Oct 24. Review.


Stat3 activation in human endometrial and cervical cancers.

Chen CL, Hsieh FC, Lieblein JC, Brown J, Chan C, Wallace JA, Cheng G, Hall BM, Lin J.

Br J Cancer. 2007 Feb 26;96(4):591-9.


Replication of heterochromatin: insights into mechanisms of epigenetic inheritance.

Wallace JA, Orr-Weaver TL.

Chromosoma. 2005 Dec;114(6):389-402. Epub 2005 Nov 15. Review.


Case study--Living wills vs. the will of loved ones.

Baumrucker SJ, Carter G, Morris GM, VandeKieft GK, Wallace JA.

Am J Hosp Palliat Care. 2005 Jul-Aug;22(4):310-4. No abstract available.


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