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Items: 1 to 50 of 163

1.

Reply to Jaffe et al.: Paleoscience precision in an archeological or historical context.

Carolin SA, Walker RT, Day CC, Ersek V, Sloan RA, Dee MW, Talebian M, Henderson GM.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4757. doi: 10.1073/pnas.1901641116. Epub 2019 Feb 21. No abstract available.

2.

Precise timing of abrupt increase in dust activity in the Middle East coincident with 4.2 ka social change.

Carolin SA, Walker RT, Day CC, Ersek V, Sloan RA, Dee MW, Talebian M, Henderson GM.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):67-72. doi: 10.1073/pnas.1808103115. Epub 2018 Dec 24.

3.
4.

Amputations: no longer the end of the road.

Turney BW, Kent SJ, Walker RT, Loftus IM.

J R Coll Surg Edinb. 2001 Oct;46(5):271-3.

PMID:
11697693
5.

5-Methyl-2'-deoxy-4'-thio-alpha-uridine (R)-S-oxide.

Sun M, Macculloch AC, Hamor TA, Walker RT.

Acta Crystallogr C. 2000 Dec;56(Pt 12):1492-3.

PMID:
11119002
6.

Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes.

Verri A, Focher F, Duncombe RJ, Basnak I, Walker RT, Coe PL, de Clercq E, Andrei G, Snoeck R, Balzarini J, Spadari S.

Biochem J. 2000 Oct 15;351 Pt 2:319-26.

7.

5-ethyl-2'-deoxy-4'-thiouridine (R)-S-oxide monohydrate.

Sun M, Macculloch AC, Hamor TA, Walker RT.

Acta Crystallogr C. 2000 Jan;56 ( Pt 1):116-7. No abstract available.

PMID:
10710692
8.

Allosteric inhibitors against HIV-1 reverse transcriptase: design and synthesis of MKC-442 analogues having an omega-functionalized acyclic structure.

Tanaka H, Walker RT, Hopkins AL, Ren J, Jones EY, Fujimoto K, Hayashi M, Miyasaka T, Baba M, Stammers DK, Stuart DI.

Antivir Chem Chemother. 1998 Jul;9(4):325-32.

PMID:
9875411
9.

Some 6-aza-5-substituted-2'-deoxyuridines show potent and selective inhibition of herpes simplex virus type 1 thymidine kinase.

Basnak I, Sun M, Hamor TA, Focher F, Verri A, Spadari S, Wroblowski B, Herdewijn P, Walker RT.

Nucleosides Nucleotides. 1998 Jan-Mar;17(1-3):187-206.

PMID:
9708347
10.

Efficient syntheses of (E)-5-(2-bromovinyl)-2'-deoxy-4'-thiouridine; a nucleoside analogue with potent biological activity.

Basnak I, Otter GP, Duncombe RJ, Westwood NB, Pietrarelli M, Hardy GW, Mills G, Rahim SG, Walker RT.

Nucleosides Nucleotides. 1998 Jan-Mar;17(1-3):29-38.

PMID:
9708340
11.

Trichomonas vaginalis thymidine kinase: purification, characterization and search for inhibitors.

Strosselli S, Spadari S, Walker RT, Basnak I, Focher F.

Biochem J. 1998 Aug 15;334 ( Pt 1):15-22.

12.

Sealing capacity in vitro of thermoplasticized gutta-percha with a solid core endodontic filling technique.

Valli KS, Rafeek RN, Walker RT.

Endod Dent Traumatol. 1998 Apr;14(2):68-71.

PMID:
9558517
13.

Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer.

Degrève B, Andrei G, Izquierdo M, Piette J, Morin K, Knaus EE, Wiebe LI, Basrah I, Walker RT, De Clercq E, Balzarini J.

Gene Ther. 1997 Oct;4(10):1107-14.

14.

DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.

Kumar S, Horton JR, Jones GD, Walker RT, Roberts RJ, Cheng X.

Nucleic Acids Res. 1997 Jul 15;25(14):2773-83.

15.
16.

Postgraduate training for specialisation.

Pollard MA, Walker RT, Curzon ME.

Br Dent J. 1996 Oct 19;181(8):302-4.

PMID:
8936770
17.

Endodontic disease: development and treatment.

Walker RT.

Prim Dent Care. 1996 Sep;3(2):53-6.

PMID:
10332329
18.

Reasons for apicectomies. A retrospective study.

el-Swiah JM, Walker RT.

Endod Dent Traumatol. 1996 Aug;12(4):185-91.

PMID:
9028182
19.

Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.

Hopkins AL, Ren J, Esnouf RM, Willcox BE, Jones EY, Ross C, Miyasaka T, Walker RT, Tanaka H, Stammers DK, Stuart DI.

J Med Chem. 1996 Apr 12;39(8):1589-600.

PMID:
8648598
20.

The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides.

Boggon TJ, Hancox EL, McAuley-Hecht KE, Connolly BA, Hunter WN, Brown T, Walker RT, Leonard GA.

Nucleic Acids Res. 1996 Mar 1;24(5):951-61.

21.

Synthesis and anti-herpes virus activity of 2'-deoxy-4'-thiopyrimidine nucleosides.

Rahim SG, Trivedi N, Bogunovic-Batchelor MV, Hardy GW, Mills G, Selway JW, Snowden W, Littler E, Coe PL, Basnak I, Whale RF, Walker RT.

J Med Chem. 1996 Feb 2;39(3):789-95.

PMID:
8576922
22.

Synthesis and antiviral activity of 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.

Tanaka H, Takashima H, Ubasawa M, Sekiya K, Inouye N, Baba M, Shigeta S, Walker RT, De Clercq E, Miyasaka T.

J Med Chem. 1995 Jul 21;38(15):2860-5.

PMID:
7636846
23.

4'-Aza-sugar nucleosides.

Pickering L, Malhi BS, Coe PL, Walker RT.

Nucleic Acids Symp Ser. 1995;(34):9-10.

PMID:
8841526
24.
25.

Preclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitro.

Baba M, Shigeta S, Yuasa S, Takashima H, Sekiya K, Ubasawa M, Tanaka H, Miyasaka T, Walker RT, De Clercq E.

Antimicrob Agents Chemother. 1994 Apr;38(4):688-92.

26.

Synthesis and properties of oligodeoxynucleotides containing the analogue 2'-deoxy-4'-thiothymidine.

Hancox EL, Connolly BA, Walker RT.

Nucleic Acids Res. 1993 Jul 25;21(15):3485-91.

27.

Effect of human serum on the in vitro anti-HIV-1 activity of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) derivatives as related to their lipophilicity and serum protein binding.

Baba M, Yuasa S, Niwa T, Yamamoto M, Yabuuchi S, Takashima H, Ubasawa M, Tanaka H, Miyasaka T, Walker RT, et al.

Biochem Pharmacol. 1993 Jun 22;45(12):2507-12.

PMID:
8328988
28.
29.

Synthesis and antiviral activity of deoxy analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.

Tanaka H, Takashima H, Ubasawa M, Sekiya K, Nitta I, Baba M, Shigeta S, Walker RT, De Clercq E, Miyasaka T.

J Med Chem. 1992 Dec 11;35(25):4713-9.

PMID:
1469700
30.

Corrosion of a nonprecious metal post: a case report.

Luu KQ, Walker RT.

Quintessence Int. 1992 Jun;23(6):389-92.

PMID:
1502316
31.

Highly potent and selective inhibition of HIV-1 replication by 6-phenylthiouracil derivatives.

Baba M, Shigeta S, Tanaka H, Miyasaka T, Ubasawa M, Umezu K, Walker RT, Pauwels R, De Clercq E.

Antiviral Res. 1992 Apr;17(4):245-64. Review. No abstract available.

PMID:
1379423
32.

The use of role-play and psychodrama in the education of the dental undergraduate.

Cheung GS, Dimmer A, Walker RT.

Aust Dent J. 1992 Feb;37(1):20-2.

PMID:
1567290
33.

Structure-activity relationships of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine analogues: effect of substitutions at the C-6 phenyl ring and at the C-5 position on anti-HIV-1 activity.

Tanaka H, Takashima H, Ubasawa M, Sekiya K, Nitta I, Baba M, Shigeta S, Walker RT, De Clercq E, Miyasaka T.

J Med Chem. 1992 Jan 24;35(2):337-45.

PMID:
1732552
34.

Some novel pyrimidine nucleoside rearrangements effected by diethylaminosulfur trifluoride (DAST).

Lloyd AE, Coe PL, Howarth OW, Walker RT.

Nucleic Acids Symp Ser. 1992;(27):185-6.

PMID:
1289812
35.

Pneumoparotid during dental treatment.

Piette E, Walker RT.

Oral Surg Oral Med Oral Pathol. 1991 Oct;72(4):415-7.

PMID:
1923438
36.

Cervical enamel projections in Chinese first permanent molars.

Zee KY, Chiu ML, Holmgren CJ, Walker RT, Corbet EF.

Aust Dent J. 1991 Oct;36(5):356-60. Review.

PMID:
1755755
37.

The synthesis and antiviral activity of some 4'-thio-2'-deoxy nucleoside analogues.

Dyson MR, Coe PL, Walker RT.

J Med Chem. 1991 Sep;34(9):2782-6.

PMID:
1654428
38.

Synergistic inhibition of human immunodeficiency virus type 1 replication by 5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil (E-EPU) and azidothymidine in vitro.

Baba M, Ito M, Shigeta S, Tanaka H, Miyasaka T, Ubasawa M, Umezu K, Walker RT, De Clercq E.

Antimicrob Agents Chemother. 1991 Jul;35(7):1430-3.

39.

Highly potent and selective inhibition of human immunodeficiency virus type 1 by a novel series of 6-substituted acyclouridine derivatives.

Baba M, De Clercq E, Tanaka H, Ubasawa M, Takashima H, Sekiya K, Nitta I, Umezu K, Walker RT, Mori S, et al.

Mol Pharmacol. 1991 Jun;39(6):805-10.

PMID:
1711148
40.
41.

Specific anti-HIV-1 "acyclonucleosides" which cannot be phosphorylated: synthesis of some deoxy analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.

Tanaka H, Baba M, Saito S, Miyasaka T, Takashima H, Sekiya K, Ubasawa M, Nitta I, Walker RT, Nakashima H, et al.

J Med Chem. 1991 Apr;34(4):1508-11. No abstract available.

PMID:
2016729
42.

Synthesis and anti-HIV activity of 2-, 3-, and 4-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).

Tanaka H, Baba M, Ubasawa M, Takashima H, Sekiya K, Nitta I, Shigeta S, Walker RT, De Clercq E, Miyasaka T.

J Med Chem. 1991 Apr;34(4):1394-9.

PMID:
2016715
43.

The synthesis and antiviral activity of some 4'-thio-2'-deoxynucleoside analogues.

Dyson MR, Coe PL, Walker RT.

Nucleic Acids Symp Ser. 1991;(24):1-4.

PMID:
1668682
44.

Synthesis and biological evaluation of some cyclic phosphoramidate nucleoside derivatives.

Kumar A, Coe PL, Jones AS, Walker RT, Balzarini J, De Clercq E.

J Med Chem. 1990 Sep;33(9):2368-75.

PMID:
2391680
45.

Synthesis and antiviral activity of 3'-deoxy-3'-C-hydroxymethyl nucleosides.

Bamford MJ, Coe PL, Walker RT.

J Med Chem. 1990 Sep;33(9):2494-501.

PMID:
2167981
46.

Synthesis and antiviral activity of some 3'-C-difluoromethyl and 3'-deoxy-3'-C-fluoromethyl nucleosides.

Bamford MJ, Coe PL, Walker RT.

J Med Chem. 1990 Sep;33(9):2488-94.

PMID:
2167980
47.

Synthesis and biological properties of novel phosphotriesters: a new approach to the introduction of biologically active nucleotides into cells.

Farrow SN, Jones AS, Kumar A, Walker RT, Balzarini J, De Clercq E.

J Med Chem. 1990 May;33(5):1400-6.

PMID:
2329561
48.

True spontaneous rupture of the common iliac vein.

Hill S, Billings PJ, Walker RT, Dormandy JA.

J R Soc Med. 1990 Feb;83(2):117. No abstract available.

49.

Synthesis of novel 6-substituted acyclouridine derivatives and their anti-HIV-1 activity.

Tanaka H, Baba M, Ubasawa M, Takashima H, Sekiya K, Nitta I, Walker RT, De Clereq E, Miyasaka T.

Nucleic Acids Symp Ser. 1990;(22):127-8.

PMID:
2101894
50.

Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.

Baba M, Tanaka H, De Clercq E, Pauwels R, Balzarini J, Schols D, Nakashima H, Perno CF, Walker RT, Miyasaka T.

Biochem Biophys Res Commun. 1989 Dec 29;165(3):1375-81.

PMID:
2575380

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