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Items: 1 to 50 of 296


Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder.

Gandal MJ, Zhang P, Hadjimichael E, Walker RL, Chen C, Liu S, Won H, van Bakel H, Varghese M, Wang Y, Shieh AW, Haney J, Parhami S, Belmont J, Kim M, Moran Losada P, Khan Z, Mleczko J, Xia Y, Dai R, Wang D, Yang YT, Xu M, Fish K, Hof PR, Warrell J, Fitzgerald D, White K, Jaffe AE; PsychENCODE Consortium, Peters MA, Gerstein M, Liu C, Iakoucheva LM, Pinto D, Geschwind DH.

Science. 2018 Dec 14;362(6420). pii: eaat8127. doi: 10.1126/science.aat8127.


Does purpose in life or ethnic identity moderate the association for racial discrimination and suicide ideation in racial/ethnic minority emerging adults?

Hong JH, Talavera DC, Odafe MO, Barr CD, Walker RL.

Cultur Divers Ethnic Minor Psychol. 2018 Nov 26. doi: 10.1037/cdp0000245. [Epub ahead of print]


Healthy volunteers' perceptions of risk in US Phase I clinical trials: A mixed-methods study.

Fisher JA, McManus L, Cottingham MD, Kalbaugh JM, Wood MM, Monahan T, Walker RL.

PLoS Med. 2018 Nov 20;15(11):e1002698. doi: 10.1371/journal.pmed.1002698. eCollection 2018 Nov.


Impact of initiatives to reduce prescription opioid risks on medically attended injuries in people using chronic opioid therapy.

Dublin S, Walker RL, Shortreed SM, Ludman EJ, Sherman KJ, Hansen RN, Thakral M, Saunders K, Parchman ML, Von Korff M.

Pharmacoepidemiol Drug Saf. 2018 Oct 30. doi: 10.1002/pds.4678. [Epub ahead of print]


Companion Animal Studies: Slipping Through a Research Oversight Gap.

Walker RL, Fisher JA.

Am J Bioeth. 2018 Oct;18(10):62-63. doi: 10.1080/15265161.2018.1513587. No abstract available.


Healthy Volunteers' Perceptions of the Benefits of Their Participation in Phase I Clinical Trials.

Fisher JA, McManus L, Wood MM, Cottingham MD, Kalbaugh JM, Monahan T, Walker RL.

J Empir Res Hum Res Ethics. 2018 Dec;13(5):494-510. doi: 10.1177/1556264618804962. Epub 2018 Oct 8.


Impact of Chronic Opioid Therapy Risk Reduction Initiatives on Opioid Overdose.

Von Korff M, Saunders K, Dublin S, Walker RL, Thakral M, Sherman KJ, Ludman EJ, Hansen RN, Parchman M, Shortreed SM.

J Pain. 2018 Sep 3. pii: S1526-5900(18)30494-2. doi: 10.1016/j.jpain.2018.08.003. [Epub ahead of print]


Exposure to Strong Anticholinergic Medications and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort.

Gray SL, Anderson ML, Hanlon JT, Dublin S, Walker RL, Hubbard RA, Yu O, Montine TJ, Crane PK, Sonnen JA, Keene CD, Larson EB.

J Alzheimers Dis. 2018;65(2):607-616. doi: 10.3233/JAD-171174.


Doctor-Patient Trust Among Chronic Pain Patients on Chronic Opioid Therapy after Opioid Risk Reduction Initiatives: A Survey.

Sherman KJ, Walker RL, Saunders K, Shortreed SM, Parchman M, Hansen RN, Thakral M, Ludman EJ, Dublin S, Von Korff M.

J Am Board Fam Med. 2018 Jul-Aug;31(4):578-587. doi: 10.3122/jabfm.2018.04.180021.


Anxiety sensitivity and acculturative stress among trauma exposed Latinx young adults.

Zvolensky MJ, Jardin C, Rogers AH, Bakhshaie J, Mayorga NA, Viana AG, Walker RL, Cardoso JB, Garey L.

Cultur Divers Ethnic Minor Psychol. 2018 Oct;24(4):470-476. doi: 10.1037/cdp0000208. Epub 2018 Jun 28.


Virtue, Vice, and "Voracious" Science: <i>How should we approach the ethics of primate research?</i>.

Walker RL.

Perspect Biol Med. 2018;61(1):130-146. doi: 10.1353/pbm.2018.0032.


Perceived Discrimination and Suicide Ideation: Moderating Roles of Anxiety Symptoms and Ethnic Identity among Asian American, African American, and Hispanic Emerging Adults.

Cheref S, Talavera D, Walker RL.

Suicide Life Threat Behav. 2018 May 3. doi: 10.1111/sltb.12467. [Epub ahead of print]


Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient.

Kouprina N, Liskovykh M, Lee NCO, Noskov VN, Waterfall JJ, Walker RL, Meltzer PS, Topol EJ, Larionov V.

Oncotarget. 2018 Feb 26;9(20):15275-15291. doi: 10.18632/oncotarget.24567. eCollection 2018 Mar 16.


Proton pump inhibitor use and the risk of fractures among an older adult cohort.

Harding BN, Weiss NS, Walker RL, Larson EB, Dublin S.

Pharmacoepidemiol Drug Saf. 2018 Jun;27(6):596-603. doi: 10.1002/pds.4406. Epub 2018 Feb 28.


The Ethics of General Population Preventive Genomic Sequencing: Rights and Social Justice.

Morrissey C, Walker RL.

J Med Philos. 2018 Jan 12;43(1):22-43. doi: 10.1093/jmp/jhx034.


Serial Participation and the Ethics of Phase 1 Healthy Volunteer Research.

Walker RL, Cottingham MD, Fisher JA.

J Med Philos. 2018 Jan 12;43(1):83-114. doi: 10.1093/jmp/jhx033.


Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways.

Gough SM, Goldberg L, Pineda M, Walker RL, Zhu YJ, Bilke S, Chung YJ, Dufraine J, Kundu S, Jacoby E, Fry TJ, Fischer S, Panzer-Grümayer R, Meltzer PS, Aplan PD.

Blood Adv. 2017 Sep 8;1(20):1749-1759. doi: 10.1182/bloodadvances.2017009837. eCollection 2017 Sep 12.


Assessing robustness of hazard ratio estimates to outcome misclassification in longitudinal panel studies with application to Alzheimer's disease.

Wang L, Hubbard RA, Walker RL, Lee EB, Larson EB, Crane PK.

PLoS One. 2017 Dec 22;12(12):e0190107. doi: 10.1371/journal.pone.0190107. eCollection 2017.


Associations between Use of Specific Analgesics and Concentrations of Amyloid-β 42 or Phospho-Tau in Regions of Human Cerebral Cortex.

Flanagan ME, Larson EB, Walker RL, Keene CD, Postupna N, Cholerton B, Sonnen JA, Dublin S, Crane PK, Montine TJ.

J Alzheimers Dis. 2018;61(2):653-662. doi: 10.3233/JAD-170414.


Impact of Opioid Dose Reduction and Risk Mitigation Initiatives on Chronic Opioid Therapy Patients at Higher Risk for Opioid-Related Adverse Outcomes.

Thakral M, Walker RL, Saunders K, Shortreed SM, Dublin S, Parchman M, Hansen RN, Ludman E, Sherman KJ, Von Korff M.

Pain Med. 2018 Dec 1;19(12):2450-2458. doi: 10.1093/pm/pnx293.


Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy.

Flynn JD, McGlinchey RP, Walker RL 3rd, Lee JC.

J Biol Chem. 2018 Jan 19;293(3):767-776. doi: 10.1074/jbc.M117.812388. Epub 2017 Nov 30.


Proton Pump Inhibitor Use and Dementia Risk: Prospective Population-Based Study.

Gray SL, Walker RL, Dublin S, Yu O, Aiello Bowles EJ, Anderson ML, Crane PK, Larson EB.

J Am Geriatr Soc. 2018 Feb;66(2):247-253. doi: 10.1111/jgs.15073. Epub 2017 Nov 14.


Infants' sensitivity to vowel harmony and its role in segmenting speech.

Mintz TH, Walker RL, Welday A, Kidd C.

Cognition. 2018 Feb;171:95-107. doi: 10.1016/j.cognition.2017.10.020. Epub 2017 Nov 7.


Health literacy and current CD4 cell count in a multiethnic U.S. sample of adults living with HIV infection.

Walker RL, Hong JH, Talavera DC, Verduzco M, Woods SP.

Int J STD AIDS. 2018 Apr;29(5):498-504. doi: 10.1177/0956462417738679. Epub 2017 Oct 25.


Comparing Pain and Depressive Symptoms of Chronic Opioid Therapy Patients Receiving Dose Reduction and Risk Mitigation Initiatives With Usual Care.

Thakral M, Walker RL, Saunders K, Shortreed SM, Parchman M, Hansen RN, Ludman E, Sherman KJ, Dublin S, Von Korff M.

J Pain. 2018 Jan;19(1):111-120. doi: 10.1016/j.jpain.2017.09.006. Epub 2017 Oct 13.


Prevalence of prescription opioid use disorder among chronic opioid therapy patients after health plan opioid dose and risk reduction initiatives.

Von Korff M, Walker RL, Saunders K, Shortreed SM, Thakral M, Parchman M, Hansen RN, Ludman E, Sherman KJ, Dublin S.

Int J Drug Policy. 2017 Aug;46:90-98. doi: 10.1016/j.drugpo.2017.05.053. Epub 2017 Jun 27.


ACSC Indicator: testing reliability for hypertension.

Walker RL, Ghali WA, Chen G, Khalsa TK, Mangat BK, Campbell NRC, Dixon E, Rabi D, Jette N, Dhanoa R, Quan H.

BMC Med Inform Decis Mak. 2017 Jun 26;17(1):90. doi: 10.1186/s12911-017-0487-4.


Risk of Alzheimer's disease or dementia following a cancer diagnosis.

Bowles EJA, Walker RL, Anderson ML, Dublin S, Crane PK, Larson EB.

PLoS One. 2017 Jun 20;12(6):e0179857. doi: 10.1371/journal.pone.0179857. eCollection 2017.


Race-related stress and hopelessness in community-based African American adults: Moderating role of social support.

Odafe MO, Salami TK, Walker RL.

Cultur Divers Ethnic Minor Psychol. 2017 Oct;23(4):561-569. doi: 10.1037/cdp0000167. Epub 2017 Jun 12.


ASD restricted and repetitive behaviors associated at 17q21.33: genes prioritized by expression in fetal brains.

Cantor RM, Navarro L, Won H, Walker RL, Lowe JK, Geschwind DH.

Mol Psychiatry. 2018 Apr;23(4):993-1000. doi: 10.1038/mp.2017.114. Epub 2017 May 23.


Use of Analgesics (Opioids and Nonsteroidal Anti-Inflammatory Drugs) and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort.

Dublin S, Walker RL, Gray SL, Hubbard RA, Anderson ML, Yu O, Montine TJ, Crane PK, Sonnen JA, Larson EB.

J Alzheimers Dis. 2017;58(2):435-448. doi: 10.3233/JAD-160374.


Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.

Goldberg L, Gough SM, Lee F, Dang C, Walker RL, Zhu YJ, Bilke S, Pineda M, Onozawa M, Jo Chung Y, Meltzer PS, Aplan PD.

Genes Chromosomes Cancer. 2017 Jun;56(6):472-483. doi: 10.1002/gcc.22451. Epub 2017 Mar 31.


Religious Coping Style and Cultural Worldview are Associated with Suicide Ideation Among African American Adults.

Walker RL, Salami T, Carter S, Flowers KC.

Arch Suicide Res. 2018 Jan-Mar;22(1):106-117. doi: 10.1080/13811118.2017.1289871. Epub 2017 Mar 1.


Religiosity Is a Protective Factor for Suicidal Ideation in European American Students but Not in African American Students.

Lester D, Walker RL.

Omega (Westport). 2017 Feb;74(3):295-303. doi: 10.1177/0030222815598452. Epub 2016 Aug 3.


A Comparative Nitrogen Balance and Productivity Analysis of Legume and Non-legume Supported Cropping Systems: The Potential Role of Biological Nitrogen Fixation.

Iannetta PP, Young M, Bachinger J, Bergkvist G, Doltra J, Lopez-Bellido RJ, Monti M, Pappa VA, Reckling M, Topp CF, Walker RL, Rees RM, Watson CA, James EK, Squire GR, Begg GS.

Front Plant Sci. 2016 Nov 21;7:1700. eCollection 2016.


Impact of an opioid risk reduction initiative on motor vehicle crash risk among chronic opioid therapy patients.

Hansen RN, Walker RL, Shortreed SM, Dublin S, Saunders K, Ludman EJ, Von Korff M.

Pharmacoepidemiol Drug Saf. 2017 Jan;26(1):47-55. doi: 10.1002/pds.4130. Epub 2016 Nov 14.


TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.

Si H, Lu H, Yang X, Mattox A, Jang M, Bian Y, Sano E, Viadiu H, Yan B, Yau C, Ng S, Lee SK, Romano RA, Davis S, Walker RL, Xiao W, Sun H, Wei L, Sinha S, Benz CC, Stuart JM, Meltzer PS, Van Waes C, Chen Z.

Oncogene. 2016 Nov 3;35(44):5781-5794. doi: 10.1038/onc.2016.112. Epub 2016 May 2.


Anxiety Mediates Perceived Discrimination and Health in African-American Women.

Carter SE, Walker RL, Cutrona CE, Simons RL, Beach SRH.

Am J Health Behav. 2016 Nov;40(6):697-704. doi: 10.5993/AJHB.40.6.2.


Glucose levels during life and neuropathologic findings at autopsy among people never treated for diabetes.

Crane PK, Walker RL, Sonnen J, Gibbons LE, Melrose R, Hassenstab J, Keene CD, Postupna N, Montine TJ, Larson EB.

Neurobiol Aging. 2016 Dec;48:72-82. doi: 10.1016/j.neurobiolaging.2016.07.021. Epub 2016 Aug 1.


Synergistic effects of pain intensity and anxiety sensitivity in relation to anxiety and depressive symptoms and disorders among economically disadvantaged latinos in a community-based primary care setting.

Velasco RV, Bakhshaie J, Walker RL, Viana AG, Garza M, Ochoa-Perez M, Paulus DJ, Robles Z, Valdivieso J, Zvolensky MJ.

J Anxiety Disord. 2016 Oct;43:23-31. doi: 10.1016/j.janxdis.2016.07.007. Epub 2016 Jul 26.


Beyond Primates: Research Protections and Animal Moral Value.

Walker RL.

Hastings Cent Rep. 2016 Jul;46(4):28-30. doi: 10.1002/hast.602.


Trade-Offs between Economic and Environmental Impacts of Introducing Legumes into Cropping Systems.

Reckling M, Bergkvist G, Watson CA, Stoddard FL, Zander PM, Walker RL, Pristeri A, Toncea I, Bachinger J.

Front Plant Sci. 2016 May 23;7:669. doi: 10.3389/fpls.2016.00669. eCollection 2016.


Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Li J, Woods SL, Healey S, Beesley J, Chen X, Lee JS, Sivakumaran H, Wayte N, Nones K, Waterfall JJ, Pearson J, Patch AM, Senz J, Ferreira MA, Kaurah P, Mackenzie R, Heravi-Moussavi A, Hansford S, Lannagan TRM, Spurdle AB, Simpson PT, da Silva L, Lakhani SR, Clouston AD, Bettington M, Grimpen F, Busuttil RA, Di Costanzo N, Boussioutas A, Jeanjean M, Chong G, Fabre A, Olschwang S, Faulkner GJ, Bellos E, Coin L, Rioux K, Bathe OF, Wen X, Martin HC, Neklason DW, Davis SR, Walker RL, Calzone KA, Avital I, Heller T, Koh C, Pineda M, Rudloff U, Quezado M, Pichurin PN, Hulick PJ, Weissman SM, Newlin A, Rubinstein WS, Sampson JE, Hamman K, Goldgar D, Poplawski N, Phillips K, Schofield L, Armstrong J, Kiraly-Borri C, Suthers GK, Huntsman DG, Foulkes WD, Carneiro F, Lindor NM, Edwards SL, French JD, Waddell N, Meltzer PS, Worthley DL, Schrader KA, Chenevix-Trench G.

Am J Hum Genet. 2016 May 5;98(5):830-842. doi: 10.1016/j.ajhg.2016.03.001. Epub 2016 Apr 14.


Glucose Levels and Risk of Frailty.

Zaslavsky O, Walker RL, Crane PK, Gray SL, Larson EB.

J Gerontol A Biol Sci Med Sci. 2016 Sep;71(9):1223-9. doi: 10.1093/gerona/glw024. Epub 2016 Mar 1.


Anesthesia Exposure and Risk of Dementia and Alzheimer's Disease: A Prospective Study.

Aiello Bowles EJ, Larson EB, Pong RP, Walker RL, Anderson ML, Yu O, Gray SL, Crane PK, Dublin S.

J Am Geriatr Soc. 2016 Mar;64(3):602-7. doi: 10.1111/jgs.14024. Epub 2016 Feb 11.


Response to Open Peer Commentaries on "Looking for Trouble: Preventive Genomic Sequencing in the General Population and the Role of Patient Choice".

Lázaro-Muñoz G, Conley JM, Davis AM, Van Riper M, Walker RL, Juengst ET.

Am J Bioeth. 2015;15(12):W6-9. doi: 10.1080/15265161.2015.1096069. No abstract available.


Calcineurin homologous proteins regulate the membrane localization and activity of sodium/proton exchangers in C. elegans.

Allman E, Wang Q, Walker RL, Austen M, Peters MA, Nehrke K.

Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C233-42. doi: 10.1152/ajpcell.00291.2015. Epub 2015 Nov 11.


The Impact of Opioid Risk Reduction Initiatives on High-Dose Opioid Prescribing for Patients on Chronic Opioid Therapy.

Von Korff M, Dublin S, Walker RL, Parchman M, Shortreed SM, Hansen RN, Saunders K.

J Pain. 2016 Jan;17(1):101-10. doi: 10.1016/j.jpain.2015.10.002. Epub 2015 Oct 22.


Professionalism and ethics in animal research.

Biller-Andorno N, Grimm H, Walker RL.

Nat Biotechnol. 2015 Oct;33(10):1027-8. doi: 10.1038/nbt.3363. No abstract available.


Tryptophan probes reveal residue-specific phospholipid interactions of apolipoprotein C-III.

Pfefferkorn CM, Walker RL 3rd, He Y, Gruschus JM, Lee JC.

Biochim Biophys Acta. 2015 Nov;1848(11 Pt A):2821-8. doi: 10.1016/j.bbamem.2015.08.018. Epub 2015 Aug 22.

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