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Identifying hypertension in pregnancy using electronic medical records: The importance of blood pressure values.

Chen L, Shortreed SM, Easterling T, Cheetham TC, Reynolds K, Avalos LA, Kamineni A, Holt V, Neugebauer R, Akosile M, Nance N, Bider-Canfield Z, Walker RL, Badon SE, Dublin S.

Pregnancy Hypertens. 2020 Jan 3;19:112-118. doi: 10.1016/j.preghy.2020.01.001. [Epub ahead of print]


From Mice to Monkeys? Beyond Orthodox Approaches to the Ethics of Animal Model Choice.

Walker RL, Eggel M.

Animals (Basel). 2020 Jan 1;10(1). pii: E77. doi: 10.3390/ani10010077.


Thymic precursor cells generate acute myeloid leukemia in NUP98-PHF23/NUP98-HOXD13 double transgenic mice.

Kundu S, Park ES, Chung YJ, Walker RL, Zhu YJ, Negi V, Meltzer PS, Aplan PD.

Sci Rep. 2019 Nov 20;9(1):17213. doi: 10.1038/s41598-019-53610-7.


Picking and Choosing Among Phase I Trials : A Qualitative Examination of How Healthy Volunteers Understand Study Risks.

Fisher JA, Monahan T, Walker RL.

J Bioeth Inq. 2019 Dec;16(4):535-549. doi: 10.1007/s11673-019-09946-w. Epub 2019 Nov 12.


Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms.

Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH.

Cell. 2019 Oct 17;179(3):750-771.e22. doi: 10.1016/j.cell.2019.09.021.


A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia.

Yin M, Baslan T, Walker RL, Zhu YJ, Freeland A, Matsukawa T, Sridharan S, Nussenzweig A, Pruitt SC, Lowe SW, Meltzer PS, Aplan PD.

JCI Insight. 2019 Dec 5;4(23). pii: 131434. doi: 10.1172/jci.insight.131434.


Development and Validation of eRADAR: A Tool Using EHR Data to Detect Unrecognized Dementia.

Barnes DE, Zhou J, Walker RL, Larson EB, Lee SJ, Boscardin WJ, Marcum ZA, Dublin S.

J Am Geriatr Soc. 2020 Jan;68(1):103-111. doi: 10.1111/jgs.16182. Epub 2019 Oct 14.


HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction.

Neckles C, Boer RE, Aboreden N, Cross AM, Walker RL, Kim BH, Kim S, Schneekloth JS Jr, Caplen NJ.

RNA. 2019 Dec;25(12):1731-1750. doi: 10.1261/rna.072454.119. Epub 2019 Sep 11.


Refining Psychological, Substance Use, and Sociodemographic Predictors of Suicide Ideation and Attempts in a National Multiethnic Sample of Adults, 2008-2013.

Cheref S, Benoit JS, Walker RL.

J Nerv Ment Dis. 2019 Aug;207(8):675-682. doi: 10.1097/NMD.0000000000001026.


Evaluation of the nutritive value of legume alternatives to soybean meal for broiler chickens.

Olukosi OA, Walker RL, Houdijk JGM.

Poult Sci. 2019 Nov 1;98(11):5778-5788. doi: 10.3382/ps/pez374.


Is Enhancement the Price of Prevention in Human Gene Editing?

Juengst ET, Henderson GE, Walker RL, Conley JM, MacKay D, Meagher KM, Saylor K, Waltz M, Kuczynski KJ, Cadigan RJ.

CRISPR J. 2018 Dec;1:351-354. doi: 10.1089/crispr.2018.0040. Epub 2018 Nov 26.


Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background.

Yin M, Chung YJ, Lindsley RC, Walker RL, Zhu YJ, Ebert BL, Meltzer PS, Aplan PD.

Blood. 2019 Jun 13;133(24):2610-2614. doi: 10.1182/blood.2018864173. Epub 2019 Apr 16.


Sleep-related problems and suicide behavior and ideation among Black and White trauma-exposed psychiatric inpatients.

Walker RL, Talavera DC, Nomamiukor F, Madubata IJ, Alfano C, Vujanovic AA.

Compr Psychiatry. 2019 May;91:22-28. doi: 10.1016/j.comppsych.2019.03.001. Epub 2019 Mar 27.


Cognitive Resilience to Alzheimer's Disease Pathology in the Human Brain.

Aiello Bowles EJ, Crane PK, Walker RL, Chubak J, LaCroix AZ, Anderson ML, Rosenberg D, Keene CD, Larson EB.

J Alzheimers Dis. 2019;68(3):1071-1083. doi: 10.3233/JAD-180942.


Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells.

Yost KE, Clatterbuck Soper SF, Walker RL, Pineda MA, Zhu YJ, Ester CD, Showman S, Roschke AV, Waterfall JJ, Meltzer PS.

Sci Rep. 2019 Mar 14;9(1):4544. doi: 10.1038/s41598-019-41058-8.


The Association Between Central Nervous System-Active Medication Use and Fall-Related Injury in Community-Dwelling Older Adults with Dementia.

Hart LA, Marcum ZA, Gray SL, Walker RL, Crane PK, Larson EB.

Pharmacotherapy. 2019 May;39(5):530-543. doi: 10.1002/phar.2244. Epub 2019 Apr 8.


Patterns of antihypertensive and statin adherence prior to dementia: findings from the adult changes in thought study.

Marcum ZA, Walker RL, Jones BL, Ramaprasan A, Gray SL, Dublin S, Crane PK, Larson EB.

BMC Geriatr. 2019 Feb 14;19(1):41. doi: 10.1186/s12877-019-1058-6.


Advancing Ethics and Policy for Healthy-Volunteer Research through a Model-Organism Framework.

Fisher JA, Walker RL.

Ethics Hum Res. 2019 Jan;41(1):4-14. doi: 10.1002/eahr.500001.


Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma.

Sun W, Chatterjee B, Shern JF, Patidar R, Song Y, Wang Y, Walker RL, Pawel BR, Linardic CM, Houghton P, Hewitt SM, Edelman DC, Khan J, Meltzer PS, Barr FG.

Int J Cancer. 2019 Jun 1;144(11):2707-2717. doi: 10.1002/ijc.32006. Epub 2019 Jan 15.


Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder.

Gandal MJ, Zhang P, Hadjimichael E, Walker RL, Chen C, Liu S, Won H, van Bakel H, Varghese M, Wang Y, Shieh AW, Haney J, Parhami S, Belmont J, Kim M, Moran Losada P, Khan Z, Mleczko J, Xia Y, Dai R, Wang D, Yang YT, Xu M, Fish K, Hof PR, Warrell J, Fitzgerald D, White K, Jaffe AE; PsychENCODE Consortium, Peters MA, Gerstein M, Liu C, Iakoucheva LM, Pinto D, Geschwind DH.

Science. 2018 Dec 14;362(6420). pii: eaat8127. doi: 10.1126/science.aat8127.


Does purpose in life or ethnic identity moderate the association for racial discrimination and suicide ideation in racial/ethnic minority emerging adults?

Hong JH, Talavera DC, Odafe MO, Barr CD, Walker RL.

Cultur Divers Ethnic Minor Psychol. 2018 Nov 26. doi: 10.1037/cdp0000245. [Epub ahead of print]


Healthy volunteers' perceptions of risk in US Phase I clinical trials: A mixed-methods study.

Fisher JA, McManus L, Cottingham MD, Kalbaugh JM, Wood MM, Monahan T, Walker RL.

PLoS Med. 2018 Nov 20;15(11):e1002698. doi: 10.1371/journal.pmed.1002698. eCollection 2018 Nov.


Impact of initiatives to reduce prescription opioid risks on medically attended injuries in people using chronic opioid therapy.

Dublin S, Walker RL, Shortreed SM, Ludman EJ, Sherman KJ, Hansen RN, Thakral M, Saunders K, Parchman ML, Von Korff M.

Pharmacoepidemiol Drug Saf. 2019 Jan;28(1):90-96. doi: 10.1002/pds.4678. Epub 2018 Oct 30.


Companion Animal Studies: Slipping Through a Research Oversight Gap.

Walker RL, Fisher JA.

Am J Bioeth. 2018 Oct;18(10):62-63. doi: 10.1080/15265161.2018.1513587. No abstract available.


Healthy Volunteers' Perceptions of the Benefits of Their Participation in Phase I Clinical Trials.

Fisher JA, McManus L, Wood MM, Cottingham MD, Kalbaugh JM, Monahan T, Walker RL.

J Empir Res Hum Res Ethics. 2018 Dec;13(5):494-510. doi: 10.1177/1556264618804962. Epub 2018 Oct 8.


Impact of Chronic Opioid Therapy Risk Reduction Initiatives on Opioid Overdose.

Von Korff M, Saunders K, Dublin S, Walker RL, Thakral M, Sherman KJ, Ludman EJ, Hansen RN, Parchman M, Shortreed SM.

J Pain. 2019 Jan;20(1):108-117. doi: 10.1016/j.jpain.2018.08.003. Epub 2018 Sep 3.


Exposure to Strong Anticholinergic Medications and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort.

Gray SL, Anderson ML, Hanlon JT, Dublin S, Walker RL, Hubbard RA, Yu O, Montine TJ, Crane PK, Sonnen JA, Keene CD, Larson EB.

J Alzheimers Dis. 2018;65(2):607-616. doi: 10.3233/JAD-171174.


Doctor-Patient Trust Among Chronic Pain Patients on Chronic Opioid Therapy after Opioid Risk Reduction Initiatives: A Survey.

Sherman KJ, Walker RL, Saunders K, Shortreed SM, Parchman M, Hansen RN, Thakral M, Ludman EJ, Dublin S, Von Korff M.

J Am Board Fam Med. 2018 Jul-Aug;31(4):578-587. doi: 10.3122/jabfm.2018.04.180021.


Anxiety sensitivity and acculturative stress among trauma exposed Latinx young adults.

Zvolensky MJ, Jardin C, Rogers AH, Bakhshaie J, Mayorga NA, Viana AG, Walker RL, Cardoso JB, Garey L.

Cultur Divers Ethnic Minor Psychol. 2018 Oct;24(4):470-476. doi: 10.1037/cdp0000208. Epub 2018 Jun 28.


Virtue, Vice, and "Voracious" Science: <i>How should we approach the ethics of primate research?</i>.

Walker RL.

Perspect Biol Med. 2018;61(1):130-146. doi: 10.1353/pbm.2018.0032.


Perceived Discrimination and Suicide Ideation: Moderating Roles of Anxiety Symptoms and Ethnic Identity among Asian American, African American, and Hispanic Emerging Adults.

Cheref S, Talavera D, Walker RL.

Suicide Life Threat Behav. 2019 Jun;49(3):665-677. doi: 10.1111/sltb.12467. Epub 2018 May 3.


Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient.

Kouprina N, Liskovykh M, Lee NCO, Noskov VN, Waterfall JJ, Walker RL, Meltzer PS, Topol EJ, Larionov V.

Oncotarget. 2018 Feb 26;9(20):15275-15291. doi: 10.18632/oncotarget.24567. eCollection 2018 Mar 16.


Proton pump inhibitor use and the risk of fractures among an older adult cohort.

Harding BN, Weiss NS, Walker RL, Larson EB, Dublin S.

Pharmacoepidemiol Drug Saf. 2018 Jun;27(6):596-603. doi: 10.1002/pds.4406. Epub 2018 Feb 28.


The Ethics of General Population Preventive Genomic Sequencing: Rights and Social Justice.

Morrissey C, Walker RL.

J Med Philos. 2018 Jan 12;43(1):22-43. doi: 10.1093/jmp/jhx034.


Serial Participation and the Ethics of Phase 1 Healthy Volunteer Research.

Walker RL, Cottingham MD, Fisher JA.

J Med Philos. 2018 Jan 12;43(1):83-114. doi: 10.1093/jmp/jhx033.


Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways.

Gough SM, Goldberg L, Pineda M, Walker RL, Zhu YJ, Bilke S, Chung YJ, Dufraine J, Kundu S, Jacoby E, Fry TJ, Fischer S, Panzer-Grümayer R, Meltzer PS, Aplan PD.

Blood Adv. 2017 Sep 8;1(20):1749-1759. doi: 10.1182/bloodadvances.2017009837. eCollection 2017 Sep 12.


Assessing robustness of hazard ratio estimates to outcome misclassification in longitudinal panel studies with application to Alzheimer's disease.

Wang L, Hubbard RA, Walker RL, Lee EB, Larson EB, Crane PK.

PLoS One. 2017 Dec 22;12(12):e0190107. doi: 10.1371/journal.pone.0190107. eCollection 2017.


Associations between Use of Specific Analgesics and Concentrations of Amyloid-β 42 or Phospho-Tau in Regions of Human Cerebral Cortex.

Flanagan ME, Larson EB, Walker RL, Keene CD, Postupna N, Cholerton B, Sonnen JA, Dublin S, Crane PK, Montine TJ.

J Alzheimers Dis. 2018;61(2):653-662. doi: 10.3233/JAD-170414.


Impact of Opioid Dose Reduction and Risk Mitigation Initiatives on Chronic Opioid Therapy Patients at Higher Risk for Opioid-Related Adverse Outcomes.

Thakral M, Walker RL, Saunders K, Shortreed SM, Dublin S, Parchman M, Hansen RN, Ludman E, Sherman KJ, Von Korff M.

Pain Med. 2018 Dec 1;19(12):2450-2458. doi: 10.1093/pm/pnx293.


Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy.

Flynn JD, McGlinchey RP, Walker RL 3rd, Lee JC.

J Biol Chem. 2018 Jan 19;293(3):767-776. doi: 10.1074/jbc.M117.812388. Epub 2017 Nov 30.


Proton Pump Inhibitor Use and Dementia Risk: Prospective Population-Based Study.

Gray SL, Walker RL, Dublin S, Yu O, Aiello Bowles EJ, Anderson ML, Crane PK, Larson EB.

J Am Geriatr Soc. 2018 Feb;66(2):247-253. doi: 10.1111/jgs.15073. Epub 2017 Nov 14.


Infants' sensitivity to vowel harmony and its role in segmenting speech.

Mintz TH, Walker RL, Welday A, Kidd C.

Cognition. 2018 Feb;171:95-107. doi: 10.1016/j.cognition.2017.10.020. Epub 2017 Nov 7.


Health literacy and current CD4 cell count in a multiethnic U.S. sample of adults living with HIV infection.

Walker RL, Hong JH, Talavera DC, Verduzco M, Woods SP.

Int J STD AIDS. 2018 Apr;29(5):498-504. doi: 10.1177/0956462417738679. Epub 2017 Oct 25.


Comparing Pain and Depressive Symptoms of Chronic Opioid Therapy Patients Receiving Dose Reduction and Risk Mitigation Initiatives With Usual Care.

Thakral M, Walker RL, Saunders K, Shortreed SM, Parchman M, Hansen RN, Ludman E, Sherman KJ, Dublin S, Von Korff M.

J Pain. 2018 Jan;19(1):111-120. doi: 10.1016/j.jpain.2017.09.006. Epub 2017 Oct 13.


Prevalence of prescription opioid use disorder among chronic opioid therapy patients after health plan opioid dose and risk reduction initiatives.

Von Korff M, Walker RL, Saunders K, Shortreed SM, Thakral M, Parchman M, Hansen RN, Ludman E, Sherman KJ, Dublin S.

Int J Drug Policy. 2017 Aug;46:90-98. doi: 10.1016/j.drugpo.2017.05.053. Epub 2017 Jun 27.


ACSC Indicator: testing reliability for hypertension.

Walker RL, Ghali WA, Chen G, Khalsa TK, Mangat BK, Campbell NRC, Dixon E, Rabi D, Jette N, Dhanoa R, Quan H.

BMC Med Inform Decis Mak. 2017 Jun 26;17(1):90. doi: 10.1186/s12911-017-0487-4.


Risk of Alzheimer's disease or dementia following a cancer diagnosis.

Bowles EJA, Walker RL, Anderson ML, Dublin S, Crane PK, Larson EB.

PLoS One. 2017 Jun 20;12(6):e0179857. doi: 10.1371/journal.pone.0179857. eCollection 2017.


Race-related stress and hopelessness in community-based African American adults: Moderating role of social support.

Odafe MO, Salami TK, Walker RL.

Cultur Divers Ethnic Minor Psychol. 2017 Oct;23(4):561-569. doi: 10.1037/cdp0000167. Epub 2017 Jun 12.


ASD restricted and repetitive behaviors associated at 17q21.33: genes prioritized by expression in fetal brains.

Cantor RM, Navarro L, Won H, Walker RL, Lowe JK, Geschwind DH.

Mol Psychiatry. 2018 Apr;23(4):993-1000. doi: 10.1038/mp.2017.114. Epub 2017 May 23.


Use of Analgesics (Opioids and Nonsteroidal Anti-Inflammatory Drugs) and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort.

Dublin S, Walker RL, Gray SL, Hubbard RA, Anderson ML, Yu O, Montine TJ, Crane PK, Sonnen JA, Larson EB.

J Alzheimers Dis. 2017;58(2):435-448. doi: 10.3233/JAD-160374.

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