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Items: 1 to 50 of 402

1.

Optogenetic and chemogenetic therapies for epilepsy.

Walker MC, Kullmann DM.

Neuropharmacology. 2019 Sep 5:107751. doi: 10.1016/j.neuropharm.2019.107751. [Epub ahead of print] Review.

PMID:
31494141
2.

Combination antioxidant therapy prevents epileptogenesis and modifies chronic epilepsy.

Shekh-Ahmad T, Lieb A, Kovac S, Gola L, Christian Wigley W, Abramov AY, Walker MC.

Redox Biol. 2019 Sep;26:101278. doi: 10.1016/j.redox.2019.101278. Epub 2019 Jul 19.

3.

Reactive oxygen species in status epilepticus.

Shekh-Ahmad T, Kovac S, Abramov AY, Walker MC.

Epilepsy Behav. 2019 Aug 1:106410. doi: 10.1016/j.yebeh.2019.07.011. [Epub ahead of print] Review.

PMID:
31378559
4.

Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study.

Walsh LK, Donelle J, Dodds L, Hawken S, Wilson K, Benchimol EI, Chakraborty P, Guttmann A, Kwong JC, MacDonald NE, Ortiz JR, Sprague AE, Top KA, Walker MC, Wen SW, Fell DB.

BMJ. 2019 Jul 10;366:l4151. doi: 10.1136/bmj.l4151.

5.

A mixed-methods evaluation of the MOREOB program in Ontario hospitals: participant knowledge, organizational culture, and experiences.

Reszel J, Weiss D, Sprague AE, Fell DB, Dunn S, Walker MC, Sidney D, Taljaard M, Peterson WE.

BMC Health Serv Res. 2019 Jul 8;19(1):460. doi: 10.1186/s12913-019-4224-9.

6.

Spatial and episodic memory tasks promote temporal lobe interictal spikes.

Vivekananda U, Bush D, Bisby JA, Diehl B, Jha A, Nachev P, Rodionov R, Burgess N, Walker MC.

Ann Neurol. 2019 Aug;86(2):304-309. doi: 10.1002/ana.25519. Epub 2019 Jun 20.

7.

Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

Pauletti A, Terrone G, Shekh-Ahmad T, Salamone A, Ravizza T, Rizzi M, Pastore A, Pascente R, Liang LP, Villa BR, Balosso S, Abramov AY, van Vliet EA, Del Giudice E, Aronica E, Patel M, Walker MC, Vezzani A.

Brain. 2019 Jul 1;142(7):e39. doi: 10.1093/brain/awz130.

PMID:
31145451
8.

Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time: A Systematic Review and Meta-analysis.

Neligan A, Noyce AJ, Gosavi TD, Shorvon SD, Köhler S, Walker MC.

JAMA Neurol. 2019 May 28. doi: 10.1001/jamaneurol.2019.1268. [Epub ahead of print]

PMID:
31135807
9.

Effect of implementation of the MOREOB program on adverse maternal and neonatal birth outcomes in Ontario, Canada: a retrospective cohort study.

Weiss D, Fell DB, Sprague AE, Walker MC, Dunn S, Reszel J, Peterson WE, Coyle D, Taljaard M.

BMC Pregnancy Childbirth. 2019 May 3;19(1):151. doi: 10.1186/s12884-019-2296-5.

10.

Assessing the Flexibility of the Prochlorosin 2.8 Scaffold for Bioengineering Applications.

Hegemann JD, Bobeica SC, Walker MC, Bothwell IR, van der Donk WA.

ACS Synth Biol. 2019 May 17;8(5):1204-1214. doi: 10.1021/acssynbio.9b00080. Epub 2019 May 8.

PMID:
31042373
11.

The role of maternal homocysteine concentration in placenta-mediated complications: findings from the Ottawa and Kingston birth cohort.

Chaudhry SH, Taljaard M, MacFarlane AJ, Gaudet LM, Smith GN, Rodger M, Rennicks White R, Walker MC, Wen SW.

BMC Pregnancy Childbirth. 2019 Feb 19;19(1):75. doi: 10.1186/s12884-019-2219-5.

12.

Investigative practice into sudden death in epilepsy: A global survey.

Kinney MO, McCluskey G, Friedman D, Walker MC, Sander JW, Shankar R.

Acta Neurol Scand. 2019 May;139(5):476-482. doi: 10.1111/ane.13080. Epub 2019 Mar 4.

PMID:
30776083
13.

Use of a maternal newborn audit and feedback system in Ontario: a collective case study.

Reszel J, Dunn SI, Sprague AE, Graham ID, Grimshaw JM, Peterson WE, Ockenden H, Wilding J, Quosdorf A, Darling EK, Fell DB, Harrold J, Lanes A, Smith GN, Taljaard M, Weiss D, Walker MC.

BMJ Qual Saf. 2019 Aug;28(8):635-644. doi: 10.1136/bmjqs-2018-008354. Epub 2019 Feb 16.

14.

Epilepsy Gene Therapy Using an Engineered Potassium Channel.

Snowball A, Chabrol E, Wykes RC, Shekh-Ahmad T, Cornford JH, Lieb A, Hughes MP, Massaro G, Rahim AA, Hashemi KS, Kullmann DM, Walker MC, Schorge S.

J Neurosci. 2019 Apr 17;39(16):3159-3169. doi: 10.1523/JNEUROSCI.1143-18.2019. Epub 2019 Feb 12.

15.

Fractal and Multifractal Properties of Electrographic Recordings of Human Brain Activity: Toward Its Use as a Signal Feature for Machine Learning in Clinical Applications.

França LGS, Miranda JGV, Leite M, Sharma NK, Walker MC, Lemieux L, Wang Y.

Front Physiol. 2018 Dec 10;9:1767. doi: 10.3389/fphys.2018.01767. eCollection 2018.

16.

Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model.

Chang BL, Leite M, Snowball A, Lieb A, Chabrol E, Walker MC, Kullmann DM, Schorge S, Wykes RC.

Dis Model Mech. 2018 Dec 14;11(12). pii: dmm036194. doi: 10.1242/dmm.036194.

17.

Perampanel and decanoic acid show synergistic action against AMPA receptors and seizures.

Augustin K, Williams S, Cunningham M, Devlin AM, Friedrich M, Jayasekera A, Hussain MA, Holliman D, Mitchell P, Jenkins A, Chen PE, Walker MC, Williams RSB.

Epilepsia. 2018 Nov;59(11):e172-e178. doi: 10.1111/epi.14578. Epub 2018 Oct 15.

PMID:
30324610
18.

Effect of high dose folic acid supplementation in pregnancy on pre-eclampsia (FACT): double blind, phase III, randomised controlled, international, multicentre trial.

Wen SW, White RR, Rybak N, Gaudet LM, Robson S, Hague W, Simms-Stewart D, Carroli G, Smith G, Fraser WD, Wells G, Davidge ST, Kingdom J, Coyle D, Fergusson D, Corsi DJ, Champagne J, Sabri E, Ramsay T, Mol BWJ, Oudijk MA, Walker MC; FACT Collaborating Group.

BMJ. 2018 Sep 12;362:k3478. doi: 10.1136/bmj.k3478.

19.

Outcomes for the First Year of Ontario's Birth Center Demonstration Project.

Sprague AE, Sidney D, Darling EK, Van Wagner V, Soderstrom B, Rogers J, Graves E, Coyle D, Sumner A, Holmberg V, Khan B, Walker MC.

J Midwifery Womens Health. 2018 Sep 10. doi: 10.1111/jmwh.12884. [Epub ahead of print]

20.

All You Need Is Fats-for Seizure Control: Using Amoeba to Advance Epilepsy Research.

Warren EC, Walker MC, Williams RSB.

Front Cell Neurosci. 2018 Jul 11;12:199. doi: 10.3389/fncel.2018.00199. eCollection 2018. Review.

21.

Biochemical autoregulatory gene therapy for focal epilepsy.

Lieb A, Qiu Y, Dixon CL, Heller JP, Walker MC, Schorge S, Kullmann DM.

Nat Med. 2018 Sep;24(9):1324-1329. doi: 10.1038/s41591-018-0103-x. Epub 2018 Jul 9.

22.

Correction to: Impaired Bioenergetics in Mutant Mitochondrial DNA Determines Cell Fate during Seizure-Like Activity.

Kovac S, Preza E, Houlden H, Walker MC, Abramov AY.

Mol Neurobiol. 2019 Jan;56(1):335. doi: 10.1007/s12035-018-1110-0.

PMID:
29779174
23.

Has the Time Come to Stratify and Score SUDEP Risk to Inform People With Epilepsy of Their Changes in Safety?

Shankar R, Newman C, Gales A, McLean BN, Hanna J, Ashby S, Walker MC, Sander JW.

Front Neurol. 2018 Apr 27;9:281. doi: 10.3389/fneur.2018.00281. eCollection 2018.

24.

Development and Application of Yeast and Phage Display of Diverse Lanthipeptides.

Hetrick KJ, Walker MC, van der Donk WA.

ACS Cent Sci. 2018 Apr 25;4(4):458-467. doi: 10.1021/acscentsci.7b00581. Epub 2018 Mar 28.

25.

Impaired Bioenergetics in Mutant Mitochondrial DNA Determines Cell Fate During Seizure-Like Activity.

Kovac S, Preza E, Houlden H, Walker MC, Abramov AY.

Mol Neurobiol. 2019 Jan;56(1):321-334. doi: 10.1007/s12035-018-1078-9. Epub 2018 Apr 27. Erratum in: Mol Neurobiol. 2018 May 19;:.

PMID:
29704197
26.

Oculomotor apraxia and disrupted sleep with nocturnal ballistic bouts in ADCY5-related disease.

Balint B, Antelmi E, Mencacci NE, Batla A, Eriksson SH, Walker MC, Bronstein AM, Bhatia KP.

Parkinsonism Relat Disord. 2018 Sep;54:103-106. doi: 10.1016/j.parkreldis.2018.04.011. Epub 2018 Apr 10.

PMID:
29680308
27.

Decreasing the risk of sudden unexpected death in epilepsy: structured communication of risk factors for premature mortality in people with epilepsy.

Shankar R, Henley W, Boland C, Laugharne R, McLean BN, Newman C, Hanna J, Ashby S, Walker MC, Sander JW.

Eur J Neurol. 2018 Sep;25(9):1121-1127. doi: 10.1111/ene.13651. Epub 2018 May 2.

PMID:
29611888
28.

Phenotypes, genotypes, and the management of paroxysmal movement disorders.

Silveira-Moriyama L, Kovac S, Kurian MA, Houlden H, Lees AJ, Walker MC, Roze E, Paciorkowski AR, Mink JW, Warner TT.

Dev Med Child Neurol. 2018 Jun;60(6):559-565. doi: 10.1111/dmcn.13744. Epub 2018 Mar 30. Review.

29.

Cannabidiol exerts antiepileptic effects by restoring hippocampal interneuron functions in a temporal lobe epilepsy model.

Khan AA, Shekh-Ahmad T, Khalil A, Walker MC, Ali AB.

Br J Pharmacol. 2018 Jun;175(11):2097-2115. doi: 10.1111/bph.14202. Epub 2018 Apr 17.

30.

KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy.

Shekh-Ahmad T, Eckel R, Dayalan Naidu S, Higgins M, Yamamoto M, Dinkova-Kostova AT, Kovac S, Abramov AY, Walker MC.

Brain. 2018 May 1;141(5):1390-1403. doi: 10.1093/brain/awy071.

PMID:
29538645
31.

A lanthipeptide library used to identify a protein-protein interaction inhibitor.

Yang X, Lennard KR, He C, Walker MC, Ball AT, Doigneaux C, Tavassoli A, van der Donk WA.

Nat Chem Biol. 2018 Apr;14(4):375-380. doi: 10.1038/s41589-018-0008-5. Epub 2018 Mar 5.

32.

Association of Timing of Weight Gain in Pregnancy With Infant Birth Weight.

Retnakaran R, Wen SW, Tan H, Zhou S, Ye C, Shen M, Smith GN, Walker MC.

JAMA Pediatr. 2018 Feb 1;172(2):136-142. doi: 10.1001/jamapediatrics.2017.4016.

33.

Accelerated Titration of Oxytocin in Nulliparous Women with Labour Dystocia: Results of the ACTION Pilot Randomized Controlled Trial.

Dy J, Rainey J, Walker MC, Fraser W, Smith GN, White RR, Waddell P, Janoudi G, Corsi DJ, Wei SQ.

J Obstet Gynaecol Can. 2018 Jun;40(6):690-697. doi: 10.1016/j.jogc.2017.08.046. Epub 2017 Dec 21.

PMID:
29276166
34.

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders.

Augustin K, Khabbush A, Williams S, Eaton S, Orford M, Cross JH, Heales SJR, Walker MC, Williams RSB.

Lancet Neurol. 2018 Jan;17(1):84-93. doi: 10.1016/S1474-4422(17)30408-8. Epub 2017 Dec 16. Review.

PMID:
29263011
35.

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

Klein P, Dingledine R, Aronica E, Bernard C, Blümcke I, Boison D, Brodie MJ, Brooks-Kayal AR, Engel J Jr, Forcelli PA, Hirsch LJ, Kaminski RM, Klitgaard H, Kobow K, Lowenstein DH, Pearl PL, Pitkänen A, Puhakka N, Rogawski MA, Schmidt D, Sillanpää M, Sloviter RS, Steinhäuser C, Vezzani A, Walker MC, Löscher W.

Epilepsia. 2018 Jan;59(1):37-66. doi: 10.1111/epi.13965. Epub 2017 Dec 15. Review.

36.

Effect of a population-level performance dashboard intervention on maternal-newborn outcomes: an interrupted time series study.

Weiss D, Dunn SI, Sprague AE, Fell DB, Grimshaw JM, Darling E, Graham ID, Harrold J, Smith GN, Peterson WE, Reszel J, Lanes A, Walker MC, Taljaard M.

BMJ Qual Saf. 2018 Jun;27(6):425-436. doi: 10.1136/bmjqs-2017-007361. Epub 2017 Nov 24.

37.

A case of pure gelastic seizures due to hypothalamic hamartoma with a benign course.

Gosavi TD, Walker MC.

Epilepsy Behav Case Rep. 2017 Jun 16;8:111-113. doi: 10.1016/j.ebcr.2017.06.004. eCollection 2017.

38.

Human hippocampal theta power indicates movement onset and distance travelled.

Bush D, Bisby JA, Bird CM, Gollwitzer S, Rodionov R, Diehl B, McEvoy AW, Walker MC, Burgess N.

Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12297-12302. doi: 10.1073/pnas.1708716114. Epub 2017 Oct 24.

39.

Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery.

Blumcke I, Spreafico R, Haaker G, Coras R, Kobow K, Bien CG, Pfäfflin M, Elger C, Widman G, Schramm J, Becker A, Braun KP, Leijten F, Baayen JC, Aronica E, Chassoux F, Hamer H, Stefan H, Rössler K, Thom M, Walker MC, Sisodiya SM, Duncan JS, McEvoy AW, Pieper T, Holthausen H, Kudernatsch M, Meencke HJ, Kahane P, Schulze-Bonhage A, Zentner J, Heiland DH, Urbach H, Steinhoff BJ, Bast T, Tassi L, Lo Russo G, Özkara C, Oz B, Krsek P, Vogelgesang S, Runge U, Lerche H, Weber Y, Honavar M, Pimentel J, Arzimanoglou A, Ulate-Campos A, Noachtar S, Hartl E, Schijns O, Guerrini R, Barba C, Jacques TS, Cross JH, Feucht M, Mühlebner A, Grunwald T, Trinka E, Winkler PA, Gil-Nagel A, Toledano Delgado R, Mayer T, Lutz M, Zountsas B, Garganis K, Rosenow F, Hermsen A, von Oertzen TJ, Diepgen TL, Avanzini G; EEBB Consortium.

N Engl J Med. 2017 Oct 26;377(17):1648-1656. doi: 10.1056/NEJMoa1703784.

40.

Letter Re "Status epilepticus-related etiology, incidence and mortality: A meta-analysis" by Lv R-J et al., 2017.

Neligan A, Walker MC.

Epilepsy Res. 2017 Nov;137:121-122. doi: 10.1016/j.eplepsyres.2017.08.015. No abstract available.

PMID:
29054512
41.

Corrigendum: Identification of Cleavage Sites Recognized by the 3C-Like Cysteine Protease within the Two Polyproteins of Strawberry Mottle Virus.

Mann KS, Walker MC, Sanfaçon H.

Front Microbiol. 2017 Sep 12;8:1762. doi: 10.3389/fmicb.2017.01762. eCollection 2017.

42.

Personalized translational epilepsy research - Novel approaches and future perspectives: Part I: Clinical and network analysis approaches.

Rosenow F, van Alphen N, Becker A, Chiocchetti A, Deichmann R, Deller T, Freiman T, Freitag CM, Gehrig J, Hermsen AM, Jedlicka P, Kell C, Klein KM, Knake S, Kullmann DM, Liebner S, Norwood BA, Omigie D, Plate K, Reif A, Reif PS, Reiss Y, Roeper J, Ronellenfitsch MW, Schorge S, Schratt G, Schwarzacher SW, Steinbach JP, Strzelczyk A, Triesch J, Wagner M, Walker MC, von Wegner F, Bauer S.

Epilepsy Behav. 2017 Nov;76:13-18. doi: 10.1016/j.yebeh.2017.06.041. Epub 2017 Sep 13. Review.

PMID:
28917501
43.

Personalized translational epilepsy research - Novel approaches and future perspectives: Part II: Experimental and translational approaches.

Bauer S, van Alphen N, Becker A, Chiocchetti A, Deichmann R, Deller T, Freiman T, Freitag CM, Gehrig J, Hermsen AM, Jedlicka P, Kell C, Klein KM, Knake S, Kullmann DM, Liebner S, Norwood BA, Omigie D, Plate K, Reif A, Reif PS, Reiss Y, Roeper J, Ronellenfitsch MW, Schorge S, Schratt G, Schwarzacher SW, Steinbach JP, Strzelczyk A, Triesch J, Wagner M, Walker MC, von Wegner F, Rosenow F.

Epilepsy Behav. 2017 Nov;76:7-12. doi: 10.1016/j.yebeh.2017.06.040. Epub 2017 Sep 14. Review.

PMID:
28917498
44.

Advanced maternal age: ethical and medical considerations for assisted reproductive technology.

Harrison BJ, Hilton TN, Rivière RN, Ferraro ZM, Deonandan R, Walker MC.

Int J Womens Health. 2017 Aug 16;9:561-570. doi: 10.2147/IJWH.S139578. eCollection 2017. Review.

45.

Trajectory of blood pressure change during pregnancy and the role of pre-gravid blood pressure: a functional data analysis approach.

Shen M, Tan H, Zhou S, Smith GN, Walker MC, Wen SW.

Sci Rep. 2017 Jul 24;7(1):6227. doi: 10.1038/s41598-017-06606-0.

46.

Maternal pre-gravid cardiometabolic health and infant birthweight: A prospective pre-conception cohort study.

Retnakaran R, Wen SW, Tan H, Zhou S, Ye C, Shen M, Smith GN, Walker MC.

Nutr Metab Cardiovasc Dis. 2017 Aug;27(8):723-730. doi: 10.1016/j.numecd.2017.05.005. Epub 2017 May 23.

PMID:
28693965
47.

Current practice and recommendations in UK epilepsy monitoring units. Report of a national survey and workshop.

Hamandi K, Beniczky S, Diehl B, Kandler RH, Pressler RM, Sen A, Solomon J, Walker MC, Bagary M; with ILAE British Chapter Workshop Attendees.

Seizure. 2017 Aug;50:92-98. doi: 10.1016/j.seizure.2017.06.015. Epub 2017 Jun 15.

48.

Response to Pre-Pregnancy Blood Pressure and Offspring Sex in the HUNT Study, Norway.

Retnakaran R, Wen SW, Tan H, Zhou S, Ye C, Shen M, Smith GN, Walker MC.

Am J Hypertens. 2017 Sep 1;30(9):e9. doi: 10.1093/ajh/hpx107. No abstract available.

PMID:
28633294
49.

Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

Pauletti A, Terrone G, Shekh-Ahmad T, Salamone A, Ravizza T, Rizzi M, Pastore A, Pascente R, Liang LP, Villa BR, Balosso S, Abramov AY, van Vliet EA, Del Giudice E, Aronica E, Antoine DJ, Patel M, Walker MC, Vezzani A.

Brain. 2017 Jul 1;140(7):1885-1899. doi: 10.1093/brain/awx117. Retraction in: Brain. 2019 Jul 1;142(7):e38.

50.

Implementation of a referral to discharge glycemic control initiative for reduction of surgical site infections in gynecologic oncology patients.

Hopkins L, Brown-Broderick J, Hearn J, Malcolm J, Chan J, Hicks-Boucher W, De Sousa F, Walker MC, Gagné S.

Gynecol Oncol. 2017 Aug;146(2):228-233. doi: 10.1016/j.ygyno.2017.05.021. Epub 2017 May 20.

PMID:
28532856

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