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Dimers Aren't Forever: CD80 Breaks up with PD-L1.

Sansom DM, Walker LSK.

Immunity. 2019 Dec 17;51(6):972-974. doi: 10.1016/j.immuni.2019.11.011.


Therapeutic Myeloperoxidase Inhibition Attenuates Neutrophil Activation, ANCA-Mediated Endothelial Damage, and Crescentic GN.

Antonelou M, Michaëlsson E, Evans RDR, Wang CJ, Henderson SR, Walker LSK, Unwin RJ, Salama AD; RAVE-ITN Investigators.

J Am Soc Nephrol. 2019 Dec 26. pii: ASN.2019060618. doi: 10.1681/ASN.2019060618. [Epub ahead of print]


Commentary: Understanding Somatic Symptoms: From Dualism to Systems, Diagnosis to Dimensions, Clinical Judgement to Clinical Science.

Walker LS.

J Pediatr Psychol. 2019 Aug 1;44(7):862-867. doi: 10.1093/jpepsy/jsz050. No abstract available.


CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells.

Ovcinnikovs V, Ross EM, Petersone L, Edner NM, Heuts F, Ntavli E, Kogimtzis A, Kennedy A, Wang CJ, Bennett CL, Sansom DM, Walker LSK.

Sci Immunol. 2019 May 31;4(35). pii: eaaw0902. doi: 10.1126/sciimmunol.aaw0902.


Somatic Symptoms in Pediatric Patients With Chronic Pain: Proposed Clinical Reference Points for the Children's Somatic Symptoms Inventory (Formerly the Children's Somatization Inventory).

Stone AL, Walker LS, Heathcote LC, Hernandez JM, Basch MC, Wilson AC, Simons LE.

J Pain. 2019 Aug;20(8):932-940. doi: 10.1016/j.jpain.2019.02.005. Epub 2019 Feb 13.


Tipping the balance: inhibitory checkpoints in intestinal homeostasis.

Joosse ME, Nederlof I, Walker LSK, Samsom JN.

Mucosal Immunol. 2019 Jan;12(1):21-35. doi: 10.1038/s41385-018-0113-5. Epub 2018 Nov 29. Review.


Mandatory minimum sentencing policies and cocaine use in the U.S., 1985-2013.

Walker LS, Mezuk B.

BMC Int Health Hum Rights. 2018 Nov 29;18(1):43. doi: 10.1186/s12914-018-0182-2.


The effect of primary care visits on other health care utilization: A randomized controlled trial of cash incentives offered to low income, uninsured adults in Virginia.

Bradley CJ, Neumark D, Walker LS.

J Health Econ. 2018 Nov;62:121-133. doi: 10.1016/j.jhealeco.2018.07.006. Epub 2018 Aug 16.


Characterization of CTLA4 Trafficking and Implications for Its Function.

Khailaie S, Rowshanravan B, Robert PA, Waters E, Halliday N, Badillo Herrera JD, Walker LSK, Sansom DM, Meyer-Hermann M.

Biophys J. 2018 Oct 2;115(7):1330-1343. doi: 10.1016/j.bpj.2018.08.020. Epub 2018 Aug 23.


T Cell/B Cell Collaboration and Autoimmunity: An Intimate Relationship.

Petersone L, Edner NM, Ovcinnikovs V, Heuts F, Ross EM, Ntavli E, Wang CJ, Walker LSK.

Front Immunol. 2018 Aug 27;9:1941. doi: 10.3389/fimmu.2018.01941. eCollection 2018. Review.


Development and Validation of a Nausea Severity Scale for Assessment of Nausea in Children with Abdominal Pain-Related Functional Gastrointestinal Disorders.

Russell AC, Stone AL, Wang A, Walker LS.

Children (Basel). 2018 Jun 1;5(6). pii: E68. doi: 10.3390/children5060068.


Is Resolution of Chronic Pain Associated With Changes in Blood Pressure-related Hypoalgesia?

de la Coba P, Bruehl S, Garber J, Smith CA, Walker LS.

Ann Behav Med. 2018 May 31;52(7):552-559. doi: 10.1093/abm/kax021.


Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells.

Zhang Y, Tech L, George LA, Acs A, Durrett RE, Hess H, Walker LSK, Tarlinton DM, Fletcher AL, Hauser AE, Toellner KM.

J Exp Med. 2018 Apr 2;215(4):1227-1243. doi: 10.1084/jem.20160832. Epub 2018 Mar 16.


Obesity and gender as status beliefs.

Gordon HL, Walker LS, Gur S, Olien JL.

Soc Sci Res. 2018 Mar;71:11-18. doi: 10.1016/j.ssresearch.2017.12.004. Epub 2017 Dec 11.


Study of an extended family with CTLA-4 deficiency suggests a CD28/CTLA-4 independent mechanism responsible for differences in disease manifestations and severity.

Hou TZ, Olbrich P, Soto JML, Sanchez B, Moreno PS, Borte S, Stauss HJ, Burns SO, Walker LSK, Pan-Hammarström Q, Hammarström L, Sansom DM, Neth O.

Clin Immunol. 2018 Mar;188:94-102. doi: 10.1016/j.clim.2018.01.001. Epub 2018 Jan 3.


MAIT cells in type 1 diabetes: a good friend turned bad.

Petersone L, Walker LSK.

Nat Immunol. 2017 Nov 16;18(12):1283-1285. doi: 10.1038/ni.3869. No abstract available.



Bruehl S, Walker LS, Smith CA.

Pain. 2017 Dec;158(12):2497-2498. doi: 10.1097/j.pain.0000000000001072. No abstract available.


Social learning pathways in the relation between parental chronic pain and daily pain severity and functional impairment in adolescents with functional abdominal pain.

Stone AL, Bruehl S, Smith CA, Garber J, Walker LS.

Pain. 2018 Feb;159(2):298-305. doi: 10.1097/j.pain.0000000000001085.


Interacting influences of gender and chronic pain status on parasympathetically mediated heart rate variability in adolescents and young adults.

Walker LS, Stone AL, Smith CA, Bruehl S, Garber J, Puzanovova M, Diedrich A.

Pain. 2017 Aug;158(8):1509-1516. doi: 10.1097/j.pain.0000000000000942.


Racial double standards and applicant selection.

Doerer SC, Webster M Jr, Walker LS.

Soc Sci Res. 2017 Aug;66:32-41. doi: 10.1016/j.ssresearch.2017.04.002. Epub 2017 Apr 13.


Immune deficiency and autoimmunity in patients with CTLA-4 (CD152) mutations.

Verma N, Burns SO, Walker LSK, Sansom DM.

Clin Exp Immunol. 2017 Oct;190(1):1-7. doi: 10.1111/cei.12997. Epub 2017 Jul 21. Review.


PD-1 and CTLA4: Two checkpoints, one pathway?

Walker LSK.

Sci Immunol. 2017 May 12;2(11). pii: eaan3864. doi: 10.1126/sciimmunol.aan3864. No abstract available.


Brief telephone-delivered cognitive behavioral therapy targeted to parents of children with functional abdominal pain: a randomized controlled trial.

Levy RL, Langer SL, van Tilburg MA, Romano JM, Murphy TB, Walker LS, Mancl LA, Claar RL, DuPen MM, Whitehead WE, Abdullah B, Swanson KS, Baker MD, Stoner SA, Christie DL, Feld AD.

Pain. 2017 Apr;158(4):618-628. doi: 10.1097/j.pain.0000000000000800.


EFIS Lecture: Understanding the CTLA-4 checkpoint in the maintenance of immune homeostasis.

Walker LSK.

Immunol Lett. 2017 Apr;184:43-50. doi: 10.1016/j.imlet.2017.02.007. Epub 2017 Feb 16. Review.


Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes.

Willcox A, Richardson SJ, Walker LSK, Kent SC, Morgan NG, Gillespie KM.

Diabetologia. 2017 Jul;60(7):1294-1303. doi: 10.1007/s00125-017-4221-7. Epub 2017 Feb 17.


Adolescents' Observations of Parent Pain Behaviors: Preliminary Measure Validation and Test of Social Learning Theory in Pediatric Chronic Pain.

Stone AL, Walker LS; Guest Editors: Cynthia A. Gerhardt, Cynthia A. Berg, Deborah J. Wiebe and Grayson N. Holmbeck.

J Pediatr Psychol. 2017 Jan 1;42(1):65-74. doi: 10.1093/jpepsy/jsw038.


Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.

Hou TZ, Verma N, Wanders J, Kennedy A, Soskic B, Janman D, Halliday N, Rowshanravan B, Worth A, Qasim W, Baxendale H, Stauss H, Seneviratne S, Neth O, Olbrich P, Hambleton S, Arkwright PD, Burns SO, Walker LS, Sansom DM.

Blood. 2017 Mar 16;129(11):1458-1468. doi: 10.1182/blood-2016-10-745174. Epub 2017 Feb 3.


Follicular T Helper Cells: A New Marker of Type 1 Diabetes Risk?

Heuts F, Edner NM, Walker LS.

Diabetes. 2017 Feb;66(2):258-260. doi: 10.2337/dbi16-0062. No abstract available.


Effects of maternal health anxiety on children's health complaints, emotional symptoms, and quality of life.

Thorgaard MV, Frostholm L, Walker LS, Stengaard-Pedersen K, Karlsson MM, Jensen JS, Fink P, Rask CU.

Eur Child Adolesc Psychiatry. 2017 May;26(5):591-601. doi: 10.1007/s00787-016-0927-1. Epub 2016 Dec 1.


Comparative efficacy of psychological therapies for improving mental health and daily functioning in irritable bowel syndrome: A systematic review and meta-analysis.

Laird KT, Tanner-Smith EE, Russell AC, Hollon SD, Walker LS.

Clin Psychol Rev. 2017 Feb;51:142-152. doi: 10.1016/j.cpr.2016.11.001. Epub 2016 Nov 8. Review.


Nausea in Children With Functional Abdominal Pain Predicts Poor Health Outcomes in Young Adulthood.

Russell AC, Stone AL, Walker LS.

Clin Gastroenterol Hepatol. 2017 May;15(5):706-711. doi: 10.1016/j.cgh.2016.07.006. Epub 2016 Jul 16.


A Rare Presentation of Isolated Congenital Splenic Hemangioma With Kasabach-Merritt Syndrome.

Dapaah-Siakwan F, Bryan C, Walker LS, Del Moral T.

J Pediatr Hematol Oncol. 2017 Jan;39(1):e29-e32.


Effects of a Cognitive Behavioral Therapy Intervention Trial to Improve Disease Outcomes in Children with Inflammatory Bowel Disease.

Levy RL, van Tilburg MA, Langer SL, Romano JM, Walker LS, Mancl LA, Murphy TB, Claar RL, Feld SI, Christie DL, Abdullah B, DuPen MM, Swanson KS, Baker MD, Stoner SA, Whitehead WE.

Inflamm Bowel Dis. 2016 Sep;22(9):2134-48. doi: 10.1097/MIB.0000000000000881.


Functional Nausea in Children: A Review of the Literature and Need for Diagnostic Criteria.

Russell AC, Stone AL, Walker LS.

Children (Basel). 2016 Mar 10;3(1). pii: E5. doi: 10.3390/children3010005. Review.


Impaired conditioned pain modulation in youth with functional abdominal pain.

Morris MC, Walker LS, Bruehl S, Stone AL, Mielock AS, Rao U.

Pain. 2016 Oct;157(10):2375-81. doi: 10.1097/j.pain.0000000000000660.


Pediatric Pain Beliefs Questionnaire: Psychometric Properties of the Short Form.

Stone AL, Walker LS, Laird KT, Shirkey KC, Smith CA.

J Pain. 2016 Sep;17(9):1036-44. doi: 10.1016/j.jpain.2016.06.006. Epub 2016 Jun 27.


Rome IV Diagnostic Questionnaires and Tables for Investigators and Clinicians.

Palsson OS, Whitehead WE, van Tilburg MA, Chang L, Chey W, Crowell MD, Keefer L, Lembo AJ, Parkman HP, Rao SS, Sperber A, Spiegel B, Tack J, Vanner S, Walker LS, Whorwell P, Yang Y.

Gastroenterology. 2016 Feb 13. pii: S0016-5085(16)00180-3. doi: 10.1053/j.gastro.2016.02.014. [Epub ahead of print]


Contemplating autoimmunity in the Aegean islands.

Walker LS, Ziegler S, Becher B.

Nat Immunol. 2016 Mar;17(3):218-20. doi: 10.1038/ni.3367.


Short-term and Long-term Efficacy of Psychological Therapies for Irritable Bowel Syndrome: A Systematic Review and Meta-analysis.

Laird KT, Tanner-Smith EE, Russell AC, Hollon SD, Walker LS.

Clin Gastroenterol Hepatol. 2016 Jul;14(7):937-947.e4. doi: 10.1016/j.cgh.2015.11.020. Epub 2015 Dec 22. Review.


Regulatory T Cells in Autoimmune Diabetes: Mechanisms of Action and Translational Potential.

Ovcinnikovs V, Walker LS.

Prog Mol Biol Transl Sci. 2015;136:245-77. doi: 10.1016/bs.pmbts.2015.08.004. Epub 2015 Sep 9. Review.


CTLA-4 and Autoimmunity: New Twists in the Tale.

Walker LSK.

Trends Immunol. 2015 Dec;36(12):760-762. doi: 10.1016/ Epub 2015 Nov 28.


The Sensitivity to Change and Responsiveness of the Adult Responses to Children's Symptoms in Children and Adolescents With Chronic Pain.

Noel M, Alberts N, Langer SL, Levy RL, Walker LS, Palermo TM.

J Pediatr Psychol. 2016 Apr;41(3):350-62. doi: 10.1093/jpepsy/jsv095. Epub 2015 Oct 22.


T-Regulatory Cells and Inflammatory and Inhibitory Cytokines in Malawian Children Residing in an Area of High and an Area of Low Malaria Transmission During Acute Uncomplicated Malaria and in Convalescence.

Nyirenda TS, Molyneux ME, Kenefeck R, Walker LS, MacLennan CA, Heyderman RS, Mandala WL.

J Pediatric Infect Dis Soc. 2015 Sep;4(3):232-41. doi: 10.1093/jpids/piu140. Epub 2015 Jan 7.


CD4 T cell differentiation in type 1 diabetes.

Walker LS, von Herrath M.

Clin Exp Immunol. 2016 Jan;183(1):16-29. doi: 10.1111/cei.12672. Epub 2015 Jul 28. Review.


Psychosocial mechanisms for the transmission of somatic symptoms from parents to children.

van Tilburg MA, Levy RL, Walker LS, Von Korff M, Feld LD, Garner M, Feld AD, Whitehead WE.

World J Gastroenterol. 2015 May 14;21(18):5532-41. doi: 10.3748/wjg.v21.i18.5532.


Heightened Temporal Summation of Pain in Patients with Functional Gastrointestinal Disorders and History of Trauma.

Sherman AL, Morris MC, Bruehl S, Westbrook TD, Walker LS.

Ann Behav Med. 2015 Dec;49(6):785-92. doi: 10.1007/s12160-015-9712-5.


Role of Coping With Symptoms in Depression and Disability: Comparison Between Inflammatory Bowel Disease and Abdominal Pain.

van Tilburg MA, Claar RL, Romano JM, Langer SL, Walker LS, Whitehead WE, Abdullah B, Christie DL, Levy RL.

J Pediatr Gastroenterol Nutr. 2015 Oct;61(4):431-6. doi: 10.1097/MPG.0000000000000841.


Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.

Chimen M, McGettrick HM, Apta B, Kuravi SJ, Yates CM, Kennedy A, Odedra A, Alassiri M, Harrison M, Martin A, Barone F, Nayar S, Hitchcock JR, Cunningham AF, Raza K, Filer A, Copland DA, Dick AD, Robinson J, Kalia N, Walker LSK, Buckley CD, Nash GB, Narendran P, Rainger GE.

Nat Med. 2015 May;21(5):467-475. doi: 10.1038/nm.3842. Epub 2015 Apr 20.


Lactose-Free Milk or Soy-Based Formulas Do Not Improve Caregivers' Distress or Perceptions of Difficult Infant Behavior.

Sherman AL, Anderson J, Rudolph CD, Walker LS.

J Pediatr Gastroenterol Nutr. 2015 Jul;61(1):119-24. doi: 10.1097/MPG.0000000000000743.


A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells.

Hou TZ, Qureshi OS, Wang CJ, Baker J, Young SP, Walker LS, Sansom DM.

J Immunol. 2015 Mar 1;194(5):2148-59. doi: 10.4049/jimmunol.1401876. Epub 2015 Jan 28.

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