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Predation and Risk Behaviors of Free-Roaming Owned Cats in Auckland, New Zealand via the Use of Animal-Borne Cameras.

Bruce SJ, Zito S, Gates MC, Aguilar G, Walker JK, Goldwater N, Dale A.

Front Vet Sci. 2019 Jul 2;6:205. doi: 10.3389/fvets.2019.00205. eCollection 2019.


United Kingdom CSF Disorders Day 2018.

Walker JK, Sinclair AJ, Mollan SP.

Neuroophthalmology. 2019 Feb 8;43(2):131-134. doi: 10.1080/01658107.2018.1561722. eCollection 2019 Apr.


Owner perceptions and management of the adverse behavioural effects of fireworks on companion animals: an update.

Gates MC, Zito S, Walker JK, Dale AR.

N Z Vet J. 2019 Jul 15:1-6. doi: 10.1080/00480169.2019.1638845. [Epub ahead of print]


The ability of a host plant to associate with different symbiotic partners affects ectomycorrhizal functioning.

Queralt M, Walker JKM, de Miguel AM, Parladé J, Anderson IC, Hortal S.

FEMS Microbiol Ecol. 2019 Jun 1;95(6). pii: fiz069. doi: 10.1093/femsec/fiz069.


Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain.

Chen Z, Doyle TM, Luongo L, Largent-Milnes TM, Giancotti LA, Kolar G, Squillace S, Boccella S, Walker JK, Pendleton A, Spiegel S, Neumann WL, Vanderah TW, Salvemini D.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10557-10562. doi: 10.1073/pnas.1820466116. Epub 2019 May 8.


Expanding the phenotype of Filippi Syndrome: a patient with early onset puberty.

Sabir A, Walker JK, Hart R.

Clin Dysmorphol. 2019 Mar 26. doi: 10.1097/MCD.0000000000000267. [Epub ahead of print] No abstract available.


Methods to Investigate the Roles for β-Arrestin-2 in Allergic Inflammatory Airway Disease.

Hegde A, Walker JKL.

Methods Mol Biol. 2019;1957:335-343. doi: 10.1007/978-1-4939-9158-7_21.


Therapeutic Potential of Targeting ß-Arrestin.

Bond RA, Lucero Garcia-Rojas EY, Hegde A, Walker JKL.

Front Pharmacol. 2019 Mar 6;10:124. doi: 10.3389/fphar.2019.00124. eCollection 2019. Review.


Assessing obesity in adult dogs and cats presenting for routine vaccination appointments in the North Island of New Zealand using electronic medical records data.

Gates MC, Zito S, Harvey LC, Dale A, Walker JK.

N Z Vet J. 2019 May;67(3):126-133. doi: 10.1080/00480169.2019.1585990.


Complete Genome Sequences of 18 Paenibacillus larvae Phages from the Western United States.

Merrill BD, Fajardo CP, Hilton JA, Payne AM, Ward AT, Walker JK, Dhalai A, Imahara C, Mangohig J, Monk J, Pascacio C, Rai P, Salisbury A, Velez K, Bloomfield TJ, Buhler B, Duncan SG, Fuhriman DA, George J, Graves K, Heaton K, Hill HL, Kim M, Knabe BK, Ririe DB, Rogers SL, Stamereilers C, Stephenson MB, Usher BK, Ward CS, Withers JM, Wright CK, Breakwell DP, Grose JH, Hope S, Tsourkas PK.

Microbiol Resour Announc. 2018 Oct 4;7(13). pii: e00966-18. doi: 10.1128/MRA.00966-18. eCollection 2018 Oct.


Small Molecule Condensin Inhibitors.

Zhao H, Petrushenko ZM, Walker JK, Baudry J, Zgurskaya HI, Rybenkov VV.

ACS Infect Dis. 2018 Dec 14;4(12):1737-1745. doi: 10.1021/acsinfecdis.8b00222. Epub 2018 Oct 22.


Genomic Analysis of 48 Paenibacillus larvae Bacteriophages.

Stamereilers C, Fajardo CP, Walker JK, Mendez KN, Castro-Nallar E, Grose JH, Hope S, Tsourkas PK.

Viruses. 2018 Jul 19;10(7). pii: E377. doi: 10.3390/v10070377.


Complete Genome Sequences of Paenibacillus larvae Phages BN12, Dragolir, Kiel007, Leyra, Likha, Pagassa, PBL1c, and Tadhana.

Walker JK, Merrill BD, Berg JA, Dhalai A, Dingman DW, Fajardo CP, Graves K, Hill HL, Hilton JA, Imahara C, Knabe BK, Mangohig J, Monk J, Mun H, Payne AM, Salisbury A, Stamereilers C, Velez K, Ward AT, Breakwell DP, Grose JH, Hope S, Tsourkas PK.

Genome Announc. 2018 Jun 14;6(24). pii: e01602-17. doi: 10.1128/genomeA.01602-17.


Commentary: Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive.

Pastva AM, Walker JKL.

Front Physiol. 2018 May 23;9:554. doi: 10.3389/fphys.2018.00554. eCollection 2018. No abstract available.


Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa.

Cooper SJ, Krishnamoorthy G, Wolloscheck D, Walker JK, Rybenkov VV, Parks JM, Zgurskaya HI.

ACS Infect Dis. 2018 Aug 10;4(8):1223-1234. doi: 10.1021/acsinfecdis.8b00036. Epub 2018 May 25.


β-Arrestin-2-Dependent Signaling Promotes CCR4-mediated Chemotaxis of Murine T-Helper Type 2 Cells.

Lin R, Choi YH, Zidar DA, Walker JKL.

Am J Respir Cell Mol Biol. 2018 Jun;58(6):745-755. doi: 10.1165/rcmb.2017-0240OC.


β-Arrestin2 mediates progression of murine primary myelofibrosis.

Rein LA, Wisler JW, Kim J, Theriot B, Huang L, Price T, Yang H, Chen M, Chen W, Sipkins D, Fedoriw Y, Walker JK, Premont RT, Lefkowitz RJ.

JCI Insight. 2017 Dec 21;2(24). pii: 98094. doi: 10.1172/jci.insight.98094.


Targeted HAS2 Expression Lessens Airway Responsiveness in Chronic Murine Allergic Airway Disease.

Walker JKL, Theriot BS, Ghio M, Trempus CS, Wong JE, McQuade VL, Liang J, Jiang D, Noble PW, Garantziotis S, Kraft M, Ingram JL.

Am J Respir Cell Mol Biol. 2017 Dec;57(6):702-710. doi: 10.1165/rcmb.2017-0095OC.


A Survey of Public Opinion on Cat (Felis catus) Predation and the Future Direction of Cat Management in New Zealand.

Walker JK, Bruce SJ, Dale AR.

Animals (Basel). 2017 Jul 3;7(7). pii: E49. doi: 10.3390/ani7070049.


Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli.

Haynes KM, Abdali N, Jhawar V, Zgurskaya HI, Parks JM, Green AT, Baudry J, Rybenkov VV, Smith JC, Walker JK.

J Med Chem. 2017 Jul 27;60(14):6205-6219. doi: 10.1021/acs.jmedchem.7b00453. Epub 2017 Jul 11.


The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein.

Woehl JL, Ramyar KX, Katz BB, Walker JK, Geisbrecht BV.

Protein Sci. 2017 Aug;26(8):1595-1608. doi: 10.1002/pro.3195. Epub 2017 May 31.


Identification of C3b-Binding Small-Molecule Complement Inhibitors Using Cheminformatics.

Garcia BL, Skaff DA, Chatterjee A, Hanning A, Walker JK, Wyckoff GJ, Geisbrecht BV.

J Immunol. 2017 May 1;198(9):3705-3718. doi: 10.4049/jimmunol.1601932. Epub 2017 Mar 15.


Owners' Perceptions of Their Animal's Behavioural Response to the Loss of an Animal Companion.

Walker JK, Waran NK, Phillips CJ.

Animals (Basel). 2016 Nov 3;6(11). pii: E68.


Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump.

Abdali N, Parks JM, Haynes KM, Chaney JL, Green AT, Wolloscheck D, Walker JK, Rybenkov VV, Baudry J, Smith JC, Zgurskaya HI.

ACS Infect Dis. 2017 Jan 13;3(1):89-98. doi: 10.1021/acsinfecdis.6b00167. Epub 2016 Nov 2.


Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice.

Forkuo GS, Kim H, Thanawala VJ, Al-Sawalha N, Valdez D, Joshi R, Parra S, Pera T, Gonnella PA, Knoll BJ, Walker JK, Penn RB, Bond RA.

Am J Respir Cell Mol Biol. 2016 Aug;55(2):234-42. doi: 10.1165/rcmb.2015-0373OC.


Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism.

Wang Y, Billon C, Walker JK, Burris TP.

ACS Chem Neurosci. 2016 Feb 17;7(2):143-8. doi: 10.1021/acschemneuro.5b00159. Epub 2015 Dec 3.


The effect of conspecific removal on behavioral and physiological responses of dairy cattle.

Walker JK, Arney DR, Waran NK, Handel IG, Phillips CJ.

J Dairy Sci. 2015 Dec;98(12):8610-22. doi: 10.3168/jds.2014-8937. Epub 2015 Oct 9.


Specificity of arrestin subtypes in regulating airway smooth muscle G protein-coupled receptor signaling and function.

Pera T, Hegde A, Deshpande DA, Morgan SJ, Tiegs BC, Theriot BS, Choi YH, Walker JK, Penn RB.

FASEB J. 2015 Oct;29(10):4227-35. doi: 10.1096/fj.15-273094. Epub 2015 Jun 23.


Quantification of beta adrenergic receptor subtypes in beta-arrestin knockout mouse airways.

Hegde A, Strachan RT, Walker JK.

PLoS One. 2015 Feb 6;10(2):e0116458. doi: 10.1371/journal.pone.0116458. eCollection 2015.


Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model.

Chen M, Hegde A, Choi YH, Theriot BS, Premont RT, Chen W, Walker JK.

Am J Respir Cell Mol Biol. 2015 Sep;53(3):346-54. doi: 10.1165/rcmb.2014-0231OC.


Role for β-arrestin in mediating paradoxical β2AR and PAR2 signaling in asthma.

Walker JK, DeFea KA.

Curr Opin Pharmacol. 2014 Jun;16:142-7. doi: 10.1016/j.coph.2014.03.007. Epub 2014 Jun 5. Review.


Editorial overview: Respiratory: GPCR signaling and the lung.

Walker JK, Fisher JT.

Curr Opin Pharmacol. 2014 Jun;16:iv-vi. doi: 10.1016/j.coph.2014.05.006. Epub 2014 Jun 2. No abstract available.


Testing the link between community structure and function for ectomycorrhizal fungi involved in a global tripartite symbiosis.

Walker JK, Cohen H, Higgins LM, Kennedy PG.

New Phytol. 2014 Apr;202(1):287-96. doi: 10.1111/nph.12638. Epub 2013 Dec 10.


GPCRs and arrestins in airways: implications for asthma.

Penn RB, Bond RA, Walker JK.

Handb Exp Pharmacol. 2014;219:387-403. doi: 10.1007/978-3-642-41199-1_20.


Reply: Adverse effects of long-acting beta-agonists on airway hyperresponsiveness.

Forkuo GS, Thanawala VJ, Al-Sawalha N, Bond RA, Walker JK.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):502. doi: 10.1165/rcmb.2013-0161LE. No abstract available.


Assessment of murine lung mechanics outcome measures: alignment with those made in asthmatics.

Walker JK, Kraft M, Fisher JT.

Front Physiol. 2013 Feb 12;3:491. doi: 10.3389/fphys.2012.00491. eCollection 2012.


β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model.

Thanawala VJ, Forkuo GS, Al-Sawalha N, Azzegagh Z, Nguyen LP, Eriksen JL, Tuvim MJ, Lowder TW, Dickey BF, Knoll BJ, Walker JK, Bond RA.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):220-9. doi: 10.1165/rcmb.2012-0364OC. Epub 2012 Nov 29.


β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway.

Nichols HL, Saffeddine M, Theriot BS, Hegde A, Polley D, El-Mays T, Vliagoftis H, Hollenberg MD, Wilson EH, Walker JK, DeFea KA.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16660-5. doi: 10.1073/pnas.1208881109. Epub 2012 Sep 25.


Living donor kidney paired donation transplantation: experience as a founding member center of the National Kidney Registry.

Leeser DB, Aull MJ, Afaneh C, Dadhania D, Charlton M, Walker JK, Hartono C, Serur D, Del Pizzo JJ, Kapur S.

Clin Transplant. 2012 May-Jun;26(3):E213-22. Epub 2012 Mar 12.


Discovery and characterization of atropisomer PH-797804, a p38 MAP kinase inhibitor, as a clinical drug candidate.

Xing L, Devadas B, Devraj RV, Selness SR, Shieh H, Walker JK, Mao M, Messing D, Samas B, Yang JZ, Anderson GD, Webb EG, Monahan JB.

ChemMedChem. 2012 Feb 6;7(2):273-80. doi: 10.1002/cmdc.201100439. Epub 2011 Dec 15.


Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice.

Lin R, Degan S, Theriot BS, Fischer BM, Strachan RT, Liang J, Pierce RA, Sunday ME, Noble PW, Kraft M, Brody AR, Walker JK.

Br J Pharmacol. 2012 Apr;165(7):2365-77. doi: 10.1111/j.1476-5381.2011.01725.x.


Investigation of the pyrazinones as PDE5 inhibitors: evaluation of regioisomeric projections into the solvent region.

Hughes RO, Maddux T, Joseph Rogier D, Lu S, Walker JK, Jon Jacobsen E, Rumsey JM, Zheng Y, Macinnes A, Bond BR, Han S.

Bioorg Med Chem Lett. 2011 Nov 1;21(21):6348-52. doi: 10.1016/j.bmcl.2011.08.106. Epub 2011 Aug 31.


Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase.

Selness SR, Devraj RV, Devadas B, Walker JK, Boehm TL, Durley RC, Shieh H, Xing L, Rucker PV, Jerome KD, Benson AG, Marrufo LD, Madsen HM, Hitchcock J, Owen TJ, Christie L, Promo MA, Hickory BS, Alvira E, Naing W, Blevis-Bal R, Messing D, Yang J, Mao MK, Yalamanchili G, Vonder Embse R, Hirsch J, Saabye M, Bonar S, Webb E, Anderson G, Monahan JB.

Bioorg Med Chem Lett. 2011 Jul 1;21(13):4066-71. doi: 10.1016/j.bmcl.2011.04.121. Epub 2011 May 11.


Design, synthesis and activity of a potent, selective series of N-aryl pyridinone inhibitors of p38 kinase.

Selness SR, Boehm TL, Walker JK, Devadas B, Durley RC, Kurumbail R, Shieh H, Xing L, Hepperle M, Rucker PV, Jerome KD, Benson AG, Marrufo LD, Madsen HM, Hitchcock J, Owen TJ, Christie L, Promo MA, Hickory BS, Alvira E, Naing W, Blevis-Bal R, Devraj RV, Messing D, Schindler JF, Hirsch J, Saabye M, Bonar S, Webb E, Anderson G, Monahan JB.

Bioorg Med Chem Lett. 2011 Jul 1;21(13):4059-65. doi: 10.1016/j.bmcl.2011.04.120. Epub 2011 May 13.


New perspectives regarding β(2) -adrenoceptor ligands in the treatment of asthma.

Walker JK, Penn RB, Hanania NA, Dickey BF, Bond RA.

Br J Pharmacol. 2011 May;163(1):18-28. doi: 10.1111/j.1476-5381.2010.01178.x. Review.


A survey of owners' perceptions of fear of fireworks in a sample of dogs and cats in New Zealand.

Dale AR, Walker JK, Farnworth MJ, Morrissey SV, Waran NK.

N Z Vet J. 2010 Dec;58(6):286-91. doi: 10.1080/00480169.2010.69403.


Acute lymphoid and gastrointestinal toxicity induced by selective p38alpha map kinase and map kinase-activated protein kinase-2 (MK2) inhibitors in the dog.

Morris DL, O'Neil SP, Devraj RV, Portanova JP, Gilles RW, Gross CJ, Curtiss SW, Komocsar WJ, Garner DS, Happa FA, Kraus LJ, Nikula KJ, Monahan JB, Selness SR, Galluppi GR, Shevlin KM, Kramer JA, Walker JK, Messing DM, Anderson DR, Mourey RJ, Whiteley LO, Daniels JS, Yang JZ, Rowlands PC, Alden CL, Davis JW 2nd, Sagartz JE.

Toxicol Pathol. 2010 Jun;38(4):606-18. doi: 10.1177/0192623310367807. Epub 2010 May 6.


1-(2-Ethoxyethyl)-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors.

Tollefson MB, Acker BA, Jacobsen EJ, Hughes RO, Walker JK, Fox DN, Palmer MJ, Freeman SK, Yu Y, Bond BR.

Bioorg Med Chem Lett. 2010 May 15;20(10):3120-4.


1-(2-(2,2,2-trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors.

Tollefson MB, Acker BA, Jacobsen EJ, Hughes RO, Walker JK, Fox DN, Palmer MJ, Freeman SK, Yu Y, Bond BR.

Bioorg Med Chem Lett. 2010 May 15;20(10):3125-8. doi: 10.1016/j.bmcl.2010.03.106. Epub 2010 Apr 3.


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