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Items: 1 to 50 of 425

1.

Persistence of the permeability transition pore in human mitochondria devoid of an assembled ATP synthase.

Carroll J, He J, Ding S, Fearnley IM, Walker JE.

Proc Natl Acad Sci U S A. 2019 Jun 18. pii: 201904005. doi: 10.1073/pnas.1904005116. [Epub ahead of print]

PMID:
31213546
2.

Extrinsic conditions influence the self-association and structure of IF1, the regulatory protein of mitochondrial ATP synthase.

Boreikaite V, Wicky BIM, Watt IN, Clarke J, Walker JE.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10354-10359. doi: 10.1073/pnas.1903535116. Epub 2019 May 7.

PMID:
31064873
3.

The structure of the catalytic domain of the ATP synthase from Mycobacterium smegmatis is a target for developing antitubercular drugs.

Zhang AT, Montgomery MG, Leslie AGW, Cook GM, Walker JE.

Proc Natl Acad Sci U S A. 2019 Jan 25. pii: 201817615. doi: 10.1073/pnas.1817615116. [Epub ahead of print]

PMID:
30683723
4.

Exosomes Derived from Human Primed Mesenchymal Stem Cells Induce Mitosis and Potentiate Growth Factor Secretion.

Yuan O, Lin C, Wagner J, Archard JA, Deng P, Halmai J, Bauer G, Fink KD, Fury B, Perotti NH, Walker JE, Pollock K, Apperson M, Butters J, Belafsky P, Farwell DG, Kuhn M, Nolta J, Anderson JD.

Stem Cells Dev. 2019 Mar 15;28(6):398-409. doi: 10.1089/scd.2018.0200. Epub 2019 Feb 26.

5.

TFS and Spt4/5 accelerate transcription through archaeal histone-based chromatin.

Sanders TJ, Lammers M, Marshall CJ, Walker JE, Lynch ER, Santangelo TJ.

Mol Microbiol. 2019 Mar;111(3):784-797. doi: 10.1111/mmi.14191. Epub 2019 Feb 1.

PMID:
30592095
6.

Inhibition of F1 -ATPase from Trypanosoma brucei by its regulatory protein inhibitor TbIF1.

Gahura O, Panicucci B, Váchová H, Walker JE, Zíková A.

FEBS J. 2018 Dec;285(23):4413-4423. doi: 10.1111/febs.14672. Epub 2018 Oct 17.

PMID:
30288927
7.

Impaired hepatic amyloid-beta degradation in Alzheimer's disease.

Maarouf CL, Walker JE, Sue LI, Dugger BN, Beach TG, Serrano GE.

PLoS One. 2018 Sep 7;13(9):e0203659. doi: 10.1371/journal.pone.0203659. eCollection 2018.

8.

Prevalence and correlates of hazardous alcohol consumption and binge drinking among men who have sex with men (MSM) in San Francisco.

Santos GM, Rowe C, Hern J, Walker JE, Ali A, Ornelaz M, Prescott M, Coffin P, McFarland W, Raymond HF.

PLoS One. 2018 Aug 17;13(8):e0202170. doi: 10.1371/journal.pone.0202170. eCollection 2018.

9.

Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4).

Beach TG, Serrano GE, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbillé AG, Letournel F, Munoz DG, White CL 3rd, Schneider J, Crary JF, Sue LI, Adler CH, Glass MJ, Intorcia AJ, Walker JE, Foroud T, Coffey CS, Ecklund D, Riss H, Goßmann J, König F, Kopil CM, Arnedo V, Riley L, Linder C, Dave KD, Jennings D, Seibyl J, Mollenhauer B, Chahine L; Systemic Synuclein Sampling Study (S4) .

J Neuropathol Exp Neurol. 2018 Sep 1;77(9):793-802. doi: 10.1093/jnen/nly056.

PMID:
30107604
10.

ATP synthase from Trypanosoma brucei has an elaborated canonical F1-domain and conventional catalytic sites.

Montgomery MG, Gahura O, Leslie AGW, Zíková A, Walker JE.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2102-2107. doi: 10.1073/pnas.1720940115. Epub 2018 Feb 12.

11.

Assembly of the membrane domain of ATP synthase in human mitochondria.

He J, Ford HC, Carroll J, Douglas C, Gonzales E, Ding S, Fearnley IM, Walker JE.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):2988-2993. doi: 10.1073/pnas.1722086115. Epub 2018 Feb 12.

12.

The F1 -ATPase from Trypanosoma brucei is elaborated by three copies of an additional p18-subunit.

Gahura O, Šubrtová K, Váchová H, Panicucci B, Fearnley IM, Harbour ME, Walker JE, Zíková A.

FEBS J. 2018 Feb;285(3):614-628. doi: 10.1111/febs.14364. Epub 2017 Dec 30.

13.

Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase.

He J, Carroll J, Ding S, Fearnley IM, Walker JE.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9086-9091. doi: 10.1073/pnas.1711201114. Epub 2017 Aug 7.

14.

Factor-dependent archaeal transcription termination.

Walker JE, Luyties O, Santangelo TJ.

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6767-E6773. doi: 10.1073/pnas.1704028114. Epub 2017 Jul 31.

15.

Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase.

Rhein VF, Carroll J, Ding S, Fearnley IM, Walker JE.

FEBS Lett. 2017 Jun;591(12):1641-1652. doi: 10.1002/1873-3468.12649. Epub 2017 Apr 27.

16.

Persistence of the mitochondrial permeability transition in the absence of subunit c of human ATP synthase.

He J, Ford HC, Carroll J, Ding S, Fearnley IM, Walker JE.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3409-3414. doi: 10.1073/pnas.1702357114. Epub 2017 Mar 13.

17.

Structure of the mitochondrial ATP synthase from Pichia angusta determined by electron cryo-microscopy.

Vinothkumar KR, Montgomery MG, Liu S, Walker JE.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12709-12714. doi: 10.1073/pnas.1615902113. Epub 2016 Oct 24.

18.

Regulation of the thermoalkaliphilic F1-ATPase from Caldalkalibacillus thermarum.

Ferguson SA, Cook GM, Montgomery MG, Leslie AG, Walker JE.

Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10860-5. doi: 10.1073/pnas.1612035113. Epub 2016 Sep 12.

19.

Cardiolipin binds selectively but transiently to conserved lysine residues in the rotor of metazoan ATP synthases.

Duncan AL, Robinson AJ, Walker JE.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8687-92. doi: 10.1073/pnas.1608396113. Epub 2016 Jul 5.

20.

NDUFAF5 Hydroxylates NDUFS7 at an Early Stage in the Assembly of Human Complex I.

Rhein VF, Carroll J, Ding S, Fearnley IM, Walker JE.

J Biol Chem. 2016 Jul 8;291(28):14851-60. doi: 10.1074/jbc.M116.734970. Epub 2016 May 18.

21.

Transcription Regulation in Archaea.

Gehring AM, Walker JE, Santangelo TJ.

J Bacteriol. 2016 Jun 27;198(14):1906-1917. doi: 10.1128/JB.00255-16. Print 2016 Jul 15. Review.

22.

Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 Å resolution.

Morales-Rios E, Montgomery MG, Leslie AG, Walker JE.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13231-6. doi: 10.1073/pnas.1517542112. Epub 2015 Oct 12.

23.

Structure of a catalytic dimer of the α- and β-subunits of the F-ATPase from Paracoccus denitrificans at 2.3 Å resolution.

Morales-Ríos E, Montgomery MG, Leslie AG, García-Trejo JJ, Walker JE.

Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1309-17. doi: 10.1107/S2053230X15016076. Epub 2015 Sep 23.

24.

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.

Zhou A, Rohou A, Schep DG, Bason JV, Montgomery MG, Walker JE, Grigorieff N, Rubinstein JL.

Elife. 2015 Oct 6;4:e10180. doi: 10.7554/eLife.10180.

25.

Purification, characterization and crystallization of the F-ATPase from Paracoccus denitrificans.

Morales-Rios E, Watt IN, Zhang Q, Ding S, Fearnley IM, Montgomery MG, Wakelam MJ, Walker JE.

Open Biol. 2015 Sep;5(9):150119. doi: 10.1098/rsob.150119.

26.

Important mitochondrial proteins in human omental adipose tissue show reduced expression in obesity.

Lindinger PW, Christe M, Eberle AN, Kern B, Peterli R, Peters T, Jayawardene KJ, Fearnley IM, Walker JE.

Data Brief. 2015 Apr 23;4:40-3. doi: 10.1016/j.dib.2015.04.007. eCollection 2015 Sep.

27.

Analyses of in vivo interactions between transcription factors and the archaeal RNA polymerase.

Walker JE, Santangelo TJ.

Methods. 2015 Sep 15;86:73-9. doi: 10.1016/j.ymeth.2015.05.023. Epub 2015 May 29.

28.

How release of phosphate from mammalian F1-ATPase generates a rotary substep.

Bason JV, Montgomery MG, Leslie AG, Walker JE.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6009-14. doi: 10.1073/pnas.1506465112. Epub 2015 Apr 27.

29.

Important mitochondrial proteins in human omental adipose tissue show reduced expression in obesity.

Lindinger PW, Christe M, Eberle AN, Kern B, Peterli R, Peters T, Jayawardene KJ, Fearnley IM, Walker JE.

J Proteomics. 2015 Jun 21;124:79-87. doi: 10.1016/j.jprot.2015.03.037. Epub 2015 Apr 10.

PMID:
25865306
30.

Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking.

Lee J, Ding S, Walpole TB, Holding AN, Montgomery MG, Fearnley IM, Walker JE.

J Biol Chem. 2015 May 22;290(21):13308-20. doi: 10.1074/jbc.M115.645283. Epub 2015 Apr 7.

31.

A Commensal Strain of Staphylococcus epidermidis Overexpresses Membrane Proteins Associated with Pathogenesis When Grown in Biofilms.

Águila-Arcos S, Ding S, Aloria K, Arizmendi JM, Fearnley IM, Walker JE, Goñi FM, Alkorta I.

J Membr Biol. 2015 Jun;248(3):431-42. doi: 10.1007/s00232-015-9801-1. Epub 2015 Apr 3.

PMID:
25837994
32.

The purification and characterization of ATP synthase complexes from the mitochondria of four fungal species.

Liu S, Charlesworth TJ, Bason JV, Montgomery MG, Harbour ME, Fearnley IM, Walker JE.

Biochem J. 2015 May 15;468(1):167-75. doi: 10.1042/BJ20150197.

33.

Conservation of complete trimethylation of lysine-43 in the rotor ring of c-subunits of metazoan adenosine triphosphate (ATP) synthases.

Walpole TB, Palmer DN, Jiang H, Ding S, Fearnley IM, Walker JE.

Mol Cell Proteomics. 2015 Apr;14(4):828-40. doi: 10.1074/mcp.M114.047456. Epub 2015 Jan 21.

34.

Pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase.

Bason JV, Montgomery MG, Leslie AG, Walker JE.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11305-10. doi: 10.1073/pnas.1411560111. Epub 2014 Jul 21.

35.

Human METTL20 methylates lysine residues adjacent to the recognition loop of the electron transfer flavoprotein in mitochondria.

Rhein VF, Carroll J, He J, Ding S, Fearnley IM, Walker JE.

J Biol Chem. 2014 Aug 29;289(35):24640-51. doi: 10.1074/jbc.M114.580464. Epub 2014 Jul 14.

36.

SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient- and exercise-induced stress.

Vassilopoulos A, Pennington JD, Andresson T, Rees DM, Bosley AD, Fearnley IM, Ham A, Flynn CR, Hill S, Rose KL, Kim HS, Deng CX, Walker JE, Gius D.

Antioxid Redox Signal. 2014 Aug 1;21(4):551-64. doi: 10.1089/ars.2013.5420. Epub 2014 Mar 6.

37.

Assembly factors for the membrane arm of human complex I.

Andrews B, Carroll J, Ding S, Fearnley IM, Walker JE.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18934-9. doi: 10.1073/pnas.1319247110. Epub 2013 Nov 4.

38.

NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I.

Rhein VF, Carroll J, Ding S, Fearnley IM, Walker JE.

J Biol Chem. 2013 Nov 15;288(46):33016-26. doi: 10.1074/jbc.M113.518803. Epub 2013 Oct 2.

39.

Post-translational modifications near the quinone binding site of mammalian complex I.

Carroll J, Ding S, Fearnley IM, Walker JE.

J Biol Chem. 2013 Aug 23;288(34):24799-808. doi: 10.1074/jbc.M113.488106. Epub 2013 Jul 8.

40.

PINK1 rendered temperature sensitive by disease-associated and engineered mutations.

Narendra DP, Wang C, Youle RJ, Walker JE.

Hum Mol Genet. 2013 Jul 1;22(13):2572-89. doi: 10.1093/hmg/ddt106. Epub 2013 Mar 3.

41.

The structure of F₁-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF₁.

Robinson GC, Bason JV, Montgomery MG, Fearnley IM, Mueller DM, Leslie AG, Walker JE.

Open Biol. 2013 Feb 13;3(2):120164. doi: 10.1098/rsob.120164.

42.

The affinity purification and characterization of ATP synthase complexes from mitochondria.

Runswick MJ, Bason JV, Montgomery MG, Robinson GC, Fearnley IM, Walker JE.

Open Biol. 2013 Feb 13;3(2):120160. doi: 10.1098/rsob.120160.

43.

The ATP synthase: the understood, the uncertain and the unknown.

Walker JE.

Biochem Soc Trans. 2013 Feb 1;41(1):1-16. doi: 10.1042/BST20110773. Review.

PMID:
23356252
44.

Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism.

Narendra D, Walker JE, Youle R.

Cold Spring Harb Perspect Biol. 2012 Nov 1;4(11). pii: a011338. doi: 10.1101/cshperspect.a011338.

45.

Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM.

Baker LA, Watt IN, Runswick MJ, Walker JE, Rubinstein JL.

Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11675-80. doi: 10.1073/pnas.1204935109. Epub 2012 Jul 2.

46.

Structural evidence of a new catalytic intermediate in the pathway of ATP hydrolysis by F1-ATPase from bovine heart mitochondria.

Rees DM, Montgomery MG, Leslie AG, Walker JE.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11139-43. doi: 10.1073/pnas.1207587109. Epub 2012 Jun 25.

47.

The effect of seizure focus on regional language processing areas.

Duke ES, Tesfaye M, Berl MM, Walker JE, Ritzl EK, Fasano RE, Conry JA, Pearl PL, Sato S, Theodore WH, Gaillard WD.

Epilepsia. 2012 Jun;53(6):1044-50. doi: 10.1111/j.1528-1167.2012.03490.x. Epub 2012 May 3.

48.

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

He J, Cooper HM, Reyes A, Di Re M, Sembongi H, Litwin TR, Gao J, Neuman KC, Fearnley IM, Spinazzola A, Walker JE, Holt IJ.

Nucleic Acids Res. 2012 Jul;40(13):6109-21. doi: 10.1093/nar/gks266. Epub 2012 Mar 26.

49.

Human C4orf14 interacts with the mitochondrial nucleoid and is involved in the biogenesis of the small mitochondrial ribosomal subunit.

He J, Cooper HM, Reyes A, Di Re M, Kazak L, Wood SR, Mao CC, Fearnley IM, Walker JE, Holt IJ.

Nucleic Acids Res. 2012 Jul;40(13):6097-108. doi: 10.1093/nar/gks257. Epub 2012 Mar 24.

50.

Generation of an HIV-1-resistant immune system with CD34(+) hematopoietic stem cells transduced with a triple-combination anti-HIV lentiviral vector.

Walker JE, Chen RX, McGee J, Nacey C, Pollard RB, Abedi M, Bauer G, Nolta JA, Anderson JS.

J Virol. 2012 May;86(10):5719-29. doi: 10.1128/JVI.06300-11. Epub 2012 Mar 7.

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