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Association of Untargeted Urinary Metabolomics and Lung Cancer Risk Among Never-Smoking Women in China.

Seow WJ, Shu XO, Nicholson JK, Holmes E, Walker DI, Hu W, Cai Q, Gao YT, Xiang YB, Moore SC, Bassig BA, Wong JYY, Zhang J, Ji BT, Boulangé CL, Kaluarachchi M, Wijeyesekera A, Zheng W, Elliott P, Rothman N, Lan Q.

JAMA Netw Open. 2019 Sep 4;2(9):e1911970. doi: 10.1001/jamanetworkopen.2019.11970.


Adolescents' application of the virtues across five cultural contexts.

Thoma SJ, Walker DI, Chen YH, Frichand A, Moulin-Stożek D, Kristjánsson K.

Dev Psychol. 2019 Oct;55(10):2181-2192. doi: 10.1037/dev0000770. Epub 2019 Jul 8.


Corrigendum to "A highly specific Escherichia coli qPCR and its comparison with existing methods for environmental waters" [Water Res. 126, 101-110].

Walker DI, McQuillan J, Taiwo M, Parks R, Stenton CA, Morgan H, Mowlem MC, Lees DN.

Water Res. 2019 Sep 15;161:652. doi: 10.1016/j.watres.2019.06.070. No abstract available.


ADAP-GC 4.0: Application of Clustering-Assisted Multivariate Curve Resolution to Spectral Deconvolution of Gas Chromatography-Mass Spectrometry Metabolomics Data.

Smirnov A, Qiu Y, Jia W, Walker DI, Jones DP, Du X.

Anal Chem. 2019 Jul 16;91(14):9069-9077. doi: 10.1021/acs.analchem.9b01424. Epub 2019 Jul 5.


Maternal serum metabolome and traffic-related air pollution exposure in pregnancy.

Yan Q, Liew Z, Uppal K, Cui X, Ling C, Heck JE, von Ehrenstein OS, Wu J, Walker DI, Jones DP, Ritz B.

Environ Int. 2019 Sep;130:104872. doi: 10.1016/j.envint.2019.05.066. Epub 2019 Jun 20.


Metabolomics of childhood exposure to perfluoroalkyl substances: a cross-sectional study.

Kingsley SL, Walker DI, Calafat AM, Chen A, Papandonatos GD, Xu Y, Jones DP, Lanphear BP, Pennell KD, Braun JM.

Metabolomics. 2019 Jun 21;15(7):95. doi: 10.1007/s11306-019-1560-z.


Assessment of the Applicability of Capsid-Integrity Assays for Detecting Infectious Norovirus Inactivated by Heat or UV Irradiation.

Walker DI, Cross LJ, Stapleton TA, Jenkins CL, Lees DN, Lowther JA.

Food Environ Virol. 2019 Sep;11(3):229-237. doi: 10.1007/s12560-019-09390-4. Epub 2019 Jun 5.


Use of F-Specific RNA Bacteriophage to Estimate Infectious Norovirus Levels in Oysters.

Lowther JA, Cross L, Stapleton T, Gustar NE, Walker DI, Sills M, Treagus S, Pollington V, Lees DN.

Food Environ Virol. 2019 Sep;11(3):247-258. doi: 10.1007/s12560-019-09383-3. Epub 2019 May 21.


Perturbations of the arginine metabolome following exposures to traffic-related air pollution in a panel of commuters with and without asthma.

Liang D, Ladva CN, Golan R, Yu T, Walker DI, Sarnat SE, Greenwald R, Uppal K, Tran V, Jones DP, Russell AG, Sarnat JA.

Environ Int. 2019 Jun;127:503-513. doi: 10.1016/j.envint.2019.04.003. Epub 2019 Apr 10.


Alterations in immune and renal biomarkers among workers occupationally exposed to low levels of trichloroethylene below current regulatory standards.

Lee KM, Zhang L, Vermeulen R, Hu W, Bassig BA, Wong JJ, Qiu C, Purdue M, Wen C, Walker DI, Jones DP, Li L, Huang Y, Rothman N, Smith MT, Lan Q.

Occup Environ Med. 2019 Jun;76(6):376-381. doi: 10.1136/oemed-2018-105583. Epub 2019 Apr 10.


Perfluoroalkyl substances, metabolomic profiling, and alterations in glucose homeostasis among overweight and obese Hispanic children: A proof-of-concept analysis.

Alderete TL, Jin R, Walker DI, Valvi D, Chen Z, Jones DP, Peng C, Gilliland FD, Berhane K, Conti DV, Goran MI, Chatzi L.

Environ Int. 2019 May;126:445-453. doi: 10.1016/j.envint.2019.02.047. Epub 2019 Mar 4.


Multigenerational metabolic profiling in the Michigan PBB registry.

Walker DI, Marder ME, Yano Y, Terrell M, Liang Y, Barr DB, Miller GW, Jones DP, Marcus M, Pennell KD.

Environ Res. 2019 May;172:182-193. doi: 10.1016/j.envres.2019.02.018. Epub 2019 Feb 13.


Critical Evaluation of CrAssphage as a Molecular Marker for Human-Derived Wastewater Contamination in the Aquatic Environment.

Farkas K, Adriaenssens EM, Walker DI, McDonald JE, Malham SK, Jones DL.

Food Environ Virol. 2019 Jun;11(2):113-119. doi: 10.1007/s12560-019-09369-1. Epub 2019 Feb 13.


Metabolome-wide association study of anti-epileptic drug treatment during pregnancy.

Walker DI, Perry-Walker K, Finnell RH, Pennell KD, Tran V, May RC, McElrath TF, Meador KJ, Pennell PB, Jones DP.

Toxicol Appl Pharmacol. 2019 Jan 15;363:122-130. doi: 10.1016/j.taap.2018.12.001. Epub 2018 Dec 4.


Metabolomic assessment of exposure to near-highway ultrafine particles.

Walker DI, Lane KJ, Liu K, Uppal K, Patton AP, Durant JL, Jones DP, Brugge D, Pennell KD.

J Expo Sci Environ Epidemiol. 2019 Jun;29(4):469-483. doi: 10.1038/s41370-018-0102-5. Epub 2018 Dec 5.


High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans.

Collins JM, Walker DI, Jones DP, Tukvadze N, Liu KH, Tran VT, Uppal K, Frediani JK, Easley KA, Shenvi N, Khadka M, Ortlund EA, Kempker RR, Blumberg HM, Ziegler TR.

PLoS One. 2018 Oct 11;13(10):e0205398. doi: 10.1371/journal.pone.0205398. eCollection 2018.


Particulate metal exposures induce plasma metabolome changes in a commuter panel study.

Ladva CN, Golan R, Liang D, Greenwald R, Walker DI, Uppal K, Raysoni AU, Tran V, Yu T, Flanders WD, Miller GW, Jones DP, Sarnat JA.

PLoS One. 2018 Sep 19;13(9):e0203468. doi: 10.1371/journal.pone.0203468. eCollection 2018.


Determination of thiocyanate in exhaled breath condensate.

Chandler JD, Horati H, Walker DI, Pagliano E, Tirouvanziam R, Veltman M, Scholte BJ, Janssens HM, Go YM, Jones DP.

Free Radic Biol Med. 2018 Oct;126:334-340. doi: 10.1016/j.freeradbiomed.2018.08.012. Epub 2018 Aug 22.


The Exposome: Molecules to Populations.

Niedzwiecki MM, Walker DI, Vermeulen R, Chadeau-Hyam M, Jones DP, Miller GW.

Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:107-127. doi: 10.1146/annurev-pharmtox-010818-021315. Epub 2018 Aug 10.


Use of high-resolution metabolomics for the identification of metabolic signals associated with traffic-related air pollution.

Liang D, Moutinho JL, Golan R, Yu T, Ladva CN, Niedzwiecki M, Walker DI, Sarnat SE, Chang HH, Greenwald R, Jones DP, Russell AG, Sarnat JA.

Environ Int. 2018 Nov;120:145-154. doi: 10.1016/j.envint.2018.07.044. Epub 2018 Aug 7.


Untargeted metabolomics reveals multiple metabolites influencing smoking-related DNA methylation.

Huang Y, Hui Q, Walker DI, Uppal K, Goldberg J, Jones DP, Vaccarino V, Sun YV.

Epigenomics. 2018 Apr 1;10(4):379-393. doi: 10.2217/epi-2017-0101. Epub 2018 Mar 12.


Escherichia coli testing and enumeration in live bivalve shellfish - Present methods and future directions.

Walker DI, Younger A, Stockley L, Baker-Austin C.

Food Microbiol. 2018 Aug;73:29-38. doi: 10.1016/ Epub 2017 Dec 23. Review.


Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics.

Niedzwiecki MM, Samant P, Walker DI, Tran V, Jones DP, Prausnitz MR, Miller GW.

Anal Chem. 2018 Mar 20;90(6):3786-3792. doi: 10.1021/acs.analchem.7b04073. Epub 2018 Feb 27.


ADAP-GC 3.2: Graphical Software Tool for Efficient Spectral Deconvolution of Gas Chromatography-High-Resolution Mass Spectrometry Metabolomics Data.

Smirnov A, Jia W, Walker DI, Jones DP, Du X.

J Proteome Res. 2018 Jan 5;17(1):470-478. doi: 10.1021/acs.jproteome.7b00633. Epub 2017 Nov 7.


A highly specific Escherichia coli qPCR and its comparison with existing methods for environmental waters.

Walker DI, McQuillan J, Taiwo M, Parks R, Stenton CA, Morgan H, Mowlem MC, Lees DN.

Water Res. 2017 Dec 1;126:101-110. doi: 10.1016/j.watres.2017.08.032. Epub 2017 Aug 25. Erratum in: Water Res. 2019 Sep 15;161:652.


Metabolomic profiles of plasma, exhaled breath condensate, and saliva are correlated with potential for air toxics detection.

Ladva CN, Golan R, Greenwald R, Yu T, Sarnat SE, Flanders WD, Uppal K, Walker DI, Tran V, Liang D, Jones DP, Sarnat JA.

J Breath Res. 2017 Dec 6;12(1):016008. doi: 10.1088/1752-7163/aa863c.


Corrigendum to "Plasma metabolomics in adults with cystic fibrosis during a pulmonary exacerbation: A pilot randomized study of high-dose vitamin D3 administration" [Metabolism vol. 70, May 2017, pages 31-41].

Alvarez JA, Chong EY, Walker DI, Chandler JD, Michalski ES, Grossmann RE, Uppal K, Li S, Frediani JK, Tirouvanziam R, Tran VT, Tangpricha V, Jones DP, Ziegler TR.

Metabolism. 2017 Sep;74:41-42. doi: 10.1016/j.metabol.2017.04.009. Epub 2017 Apr 26. No abstract available.


Plasma metabolomics in adults with cystic fibrosis during a pulmonary exacerbation: A pilot randomized study of high-dose vitamin D3 administration.

Alvarez JA, Chong EY, Walker DI, Chandler JD, Michalski ES, Grossmann RE, Uppal K, Li S, Frediani JK, Tirouvanziam R, Tran VT, Tangpricha V, Jones DP, Ziegler TR.

Metabolism. 2017 May;70:31-41. doi: 10.1016/j.metabol.2017.02.006. Epub 2017 Feb 11. Erratum in: Metabolism. 2017 Sep;74:41-42.


xMSannotator: An R Package for Network-Based Annotation of High-Resolution Metabolomics Data.

Uppal K, Walker DI, Jones DP.

Anal Chem. 2017 Jan 17;89(2):1063-1067. doi: 10.1021/acs.analchem.6b01214. Epub 2017 Jan 4.


High-resolution metabolomics of occupational exposure to trichloroethylene.

Walker DI, Uppal K, Zhang L, Vermeulen R, Smith M, Hu W, Purdue MP, Tang X, Reiss B, Kim S, Li L, Huang H, Pennell KD, Jones DP, Rothman N, Lan Q.

Int J Epidemiol. 2016 Oct;45(5):1517-1527. Epub 2016 Oct 5.


Computational Metabolomics: A Framework for the Million Metabolome.

Uppal K, Walker DI, Liu K, Li S, Go YM, Jones DP.

Chem Res Toxicol. 2016 Dec 19;29(12):1956-1975. Epub 2016 Oct 12. Review.


Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice.

de Sousa Rodrigues ME, Bekhbat M, Houser MC, Chang J, Walker DI, Jones DP, Oller do Nascimento CMP, Barnum CJ, Tansey MG.

Brain Behav Immun. 2017 Jan;59:158-172. doi: 10.1016/j.bbi.2016.08.021. Epub 2016 Sep 2.


High-Resolution Metabolomics for Nutrition and Health Assessment of Armed Forces Personnel.

Accardi CJ, Walker DI, Uppal K, Quyyumi AA, Rohrbeck P, Pennell KD, Mallon CT, Jones DP.

J Occup Environ Med. 2016 Aug;58(8 Suppl 1):S80-8. doi: 10.1097/JOM.0000000000000770.


High-Resolution Metabolomics Assessment of Military Personnel: Evaluating Analytical Strategies for Chemical Detection.

Liu KH, Walker DI, Uppal K, Tran V, Rohrbeck P, Mallon TM, Jones DP.

J Occup Environ Med. 2016 Aug;58(8 Suppl 1):S53-61. doi: 10.1097/JOM.0000000000000773.


Pilot Metabolome-Wide Association Study of Benzo(a)pyrene in Serum From Military Personnel.

Walker DI, Pennell KD, Uppal K, Xia X, Hopke PK, Utell MJ, Phipps RP, Sime PJ, Rohrbeck P, Mallon CT, Jones DP.

J Occup Environ Med. 2016 Aug;58(8 Suppl 1):S44-52. doi: 10.1097/JOM.0000000000000772.


Introduction to Department of Defense Research on Burn Pits, Biomarkers, and Health Outcomes Related to Deployment in Iraq and Afghanistan.

Mallon CT, Rohrbeck MP, Haines MK, Jones DP, Utell M, Hopke PK, Phipps RP, Walker DI, Thatcher T, Woeller CF, Baird CP, Pollard HB, Dalgard CL, Gaydos JC.

J Occup Environ Med. 2016 Aug;58(8 Suppl 1):S3-S11. doi: 10.1097/JOM.0000000000000775.


Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics.

Walker DI, Mallon CT, Hopke PK, Uppal K, Go YM, Rohrbeck P, Pennell KD, Jones DP.

J Occup Environ Med. 2016 Aug;58(8 Suppl 1):S12-21. doi: 10.1097/JOM.0000000000000768.


Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel.

Jones DP, Walker DI, Uppal K, Rohrbeck P, Mallon CT, Go YM.

J Occup Environ Med. 2016 Aug;58(8 Suppl 1):S111-6. doi: 10.1097/JOM.0000000000000763.


Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exposome Research.

Go YM, Walker DI, Liang Y, Uppal K, Soltow QA, Tran V, Strobel F, Quyyumi AA, Ziegler TR, Pennell KD, Miller GW, Jones DP.

Toxicol Sci. 2015 Dec;148(2):531-43. doi: 10.1093/toxsci/kfv198. Epub 2015 Sep 9.


Comparative Proteomic Analysis of Carbonylated Proteins from the Striatum and Cortex of Pesticide-Treated Mice.

Coughlan C, Walker DI, Lohr KM, Richardson JR, Saba LM, Caudle WM, Fritz KS, Roede JR.

Parkinsons Dis. 2015;2015:812532. doi: 10.1155/2015/812532. Epub 2015 Aug 9.


Metabolome-Wide Association Study of Primary Open Angle Glaucoma.

Burgess LG, Uppal K, Walker DI, Roberson RM, Tran V, Parks MB, Wade EA, May AT, Umfress AC, Jarrell KL, Stanley BO, Kuchtey J, Kuchtey RW, Jones DP, Brantley MA Jr.

Invest Ophthalmol Vis Sci. 2015 Jul;56(8):5020-8. doi: 10.1167/iovs.15-16702.


Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.

Pillai VB, Samant S, Sundaresan NR, Raghuraman H, Kim G, Bonner MY, Arbiser JL, Walker DI, Jones DP, Gius D, Gupta MP.

Nat Commun. 2015 Apr 14;6:6656. doi: 10.1038/ncomms7656.


Metabolome-wide association study of phenylalanine in plasma of common marmosets.

Go YM, Walker DI, Soltow QA, Uppal K, Wachtman LM, Strobel FH, Pennell K, Promislow DE, Jones DP.

Amino Acids. 2015 Mar;47(3):589-601. doi: 10.1007/s00726-014-1893-x. Epub 2014 Dec 21.


Disturbed flow induces systemic changes in metabolites in mouse plasma: a metabolomics study using ApoE⁻/⁻ mice with partial carotid ligation.

Go YM, Kim CW, Walker DI, Kang DW, Kumar S, Orr M, Uppal K, Quyyumi AA, Jo H, Jones DP.

Am J Physiol Regul Integr Comp Physiol. 2015 Jan 1;308(1):R62-72. doi: 10.1152/ajpregu.00278.2014. Epub 2014 Nov 5.


Plasma metabolomics in human pulmonary tuberculosis disease: a pilot study.

Frediani JK, Jones DP, Tukvadze N, Uppal K, Sanikidze E, Kipiani M, Tran VT, Hebbar G, Walker DI, Kempker RR, Kurani SS, Colas RA, Dalli J, Tangpricha V, Serhan CN, Blumberg HM, Ziegler TR.

PLoS One. 2014 Oct 15;9(10):e108854. doi: 10.1371/journal.pone.0108854. eCollection 2014.


Mitochondrial metabolomics using high-resolution Fourier-transform mass spectrometry.

Go YM, Uppal K, Walker DI, Tran V, Dury L, Strobel FH, Baubichon-Cortay H, Pennell KD, Roede JR, Jones DP.

Methods Mol Biol. 2014;1198:43-73. doi: 10.1007/978-1-4939-1258-2_4.


Hydrolyzed Poly(acrylonitrile) Electrospun Ion-Exchange Fibers.

Jassal M, Bhowmick S, Sengupta S, Patra PK, Walker DI.

Environ Eng Sci. 2014 Jun 1;31(6):288-299.


Effectiveness of a multimedia outreach kit for families of wounded veterans.

Walker DI, Cardin JF, Chawla N, Topp D, Burton T, Macdermid Wadsworth S.

Disabil Health J. 2014 Apr;7(2):216-25. doi: 10.1016/j.dhjo.2013.11.004. Epub 2013 Nov 8.


Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems.

Go YM, Roede JR, Walker DI, Duong DM, Seyfried NT, Orr M, Liang Y, Pennell KD, Jones DP.

Mol Cell Proteomics. 2013 Nov;12(11):3285-96. doi: 10.1074/mcp.M113.030437. Epub 2013 Aug 14.


Exposure to the polybrominated diphenyl ether mixture DE-71 damages the nigrostriatal dopamine system: role of dopamine handling in neurotoxicity.

Bradner JM, Suragh TA, Wilson WW, Lazo CR, Stout KA, Kim HM, Wang MZ, Walker DI, Pennell KD, Richardson JR, Miller GW, Caudle WM.

Exp Neurol. 2013 Mar;241:138-47. doi: 10.1016/j.expneurol.2012.12.013. Epub 2012 Dec 31.

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