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Items: 1 to 50 of 469

1.

Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis.

Khakhum N, Bharaj P, Myers JN, Tapia D, Walker DH, Endsley JJ, Torres AG.

PLoS Negl Trop Dis. 2019 Jul 15;13(7):e0007578. doi: 10.1371/journal.pntd.0007578. eCollection 2019 Jul.

2.

A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri Atlantic Rainforest strain.

Londoño AF, Mendell NL, Walker DH, Bouyer DH.

PLoS Negl Trop Dis. 2019 Jun 19;13(6):e0007054. doi: 10.1371/journal.pntd.0007054. eCollection 2019 Jun.

3.

A Cluster of Cases of Rocky Mountain Spotted Fever in an Area Of Colombia Not Known to be Endemic for This Disease.

Londoño AF, Arango-Ferreira C, Acevedo-Gutiérrez LY, Paternina LE, Montes C, Ruiz I, Labruna MB, Díaz FJ, Walker DH, Rodas JD.

Am J Trop Med Hyg. 2019 Aug;101(2):336-342. doi: 10.4269/ajtmh.18-1007.

PMID:
31162015
4.

Seek and You Shall Find - Unknown Pathogens?

Vasilakis N, Walker DH.

N Engl J Med. 2019 May 30;380(22):2174-2175. doi: 10.1056/NEJMe1901212. No abstract available.

PMID:
31141642
5.

Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas.

Blanton LS, Vohra RF, Fistein L, Quade B, Walker DH, Bouyer DH.

Vector Borne Zoonotic Dis. 2019 Mar 5. doi: 10.1089/vbz.2018.2402. [Epub ahead of print]

PMID:
30835649
6.

Burkholderia pseudomallei ΔtonB Δhcp1 Live Attenuated Vaccine Strain Elicits Full Protective Immunity against Aerosolized Melioidosis Infection.

Khakhum N, Bharaj P, Myers JN, Tapia D, Kilgore PB, Ross BN, Walker DH, Endsley JJ, Torres AG.

mSphere. 2019 Jan 2;4(1). pii: e00570-18. doi: 10.1128/mSphere.00570-18.

7.

Vector Tick Transmission Model of Spotted Fever Rickettsiosis.

Saito TB, Bechelli J, Smalley C, Karim S, Walker DH.

Am J Pathol. 2019 Jan;189(1):115-123. doi: 10.1016/j.ajpath.2018.09.005. Epub 2018 Oct 11.

PMID:
30315767
8.

Atg5 Supports Rickettsia australis Infection in Macrophages In Vitro and In Vivo.

Bechelli J, Vergara L, Smalley C, Buzhdygan TP, Bender S, Zhang W, Liu Y, Popov VL, Wang J, Garg N, Hwang S, Walker DH, Fang R.

Infect Immun. 2018 Dec 19;87(1). pii: e00651-18. doi: 10.1128/IAI.00651-18. Print 2019 Jan.

9.

Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection.

Sahni A, Fang R, Sahni SK, Walker DH.

Annu Rev Pathol. 2019 Jan 24;14:127-152. doi: 10.1146/annurev-pathmechdis-012418-012800. Epub 2018 Aug 27.

PMID:
30148688
10.

Analysis of Health-Care Charges in Murine Typhus: Need for Improved Clinical Recognition and Diagnostics for Acute Disease.

Vohra RF, Walker DH, Blanton LS.

Am J Trop Med Hyg. 2018 Jun;98(6):1594-1598. doi: 10.4269/ajtmh.17-0411. Epub 2018 Apr 5.

11.

Correction: CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection.

Xu G, Mendell NL, Liang Y, Shelite TR, Goez-Rivillas Y, Soong L, Bouyer DH, Walker DH.

PLoS Negl Trop Dis. 2017 Dec 6;11(12):e0006127. doi: 10.1371/journal.pntd.0006127. eCollection 2017 Dec.

12.

A review of the global epidemiology of scrub typhus.

Xu G, Walker DH, Jupiter D, Melby PC, Arcari CM.

PLoS Negl Trop Dis. 2017 Nov 3;11(11):e0006062. doi: 10.1371/journal.pntd.0006062. eCollection 2017 Nov. Review.

13.

A Phase 1 and 2 study of Filanesib alone and in combination with low-dose dexamethasone in relapsed/refractory multiple myeloma.

Shah JJ, Kaufman JL, Zonder JA, Cohen AD, Bensinger WI, Hilder BW, Rush SA, Walker DH, Tunquist BJ, Litwiler KS, Ptaszynski M, Orlowski RZ, Lonial S.

Cancer. 2017 Dec 1;123(23):4617-4630. doi: 10.1002/cncr.30892. Epub 2017 Aug 17.

14.

Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium.

Sahni A, Patel J, Narra HP, Schroeder CLC, Walker DH, Sahni SK.

PLoS One. 2017 Aug 14;12(8):e0183181. doi: 10.1371/journal.pone.0183181. eCollection 2017.

15.

CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection.

Xu G, Mendell NL, Liang Y, Shelite TR, Goez-Rivillas Y, Soong L, Bouyer DH, Walker DH.

PLoS Negl Trop Dis. 2017 Jul 19;11(7):e0005763. doi: 10.1371/journal.pntd.0005763. eCollection 2017 Jul. Erratum in: PLoS Negl Trop Dis. 2017 Dec 6;11(12 ):e0006127.

16.

Rickettsiae as Emerging Infectious Agents.

Fang R, Blanton LS, Walker DH.

Clin Lab Med. 2017 Jun;37(2):383-400. doi: 10.1016/j.cll.2017.01.009. Review.

PMID:
28457356
17.

Time to Worry about Anthrax Again.

Keim PS, Walker DH, Zilinskas RA.

Sci Am. 2017 Mar 14;316(4):70-75. doi: 10.1038/scientificamerican0417-70. No abstract available.

PMID:
28296844
18.

Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection.

Mendell NL, Bouyer DH, Walker DH.

PLoS Negl Trop Dis. 2017 Mar 10;11(3):e0005453. doi: 10.1371/journal.pntd.0005453. eCollection 2017 Mar.

19.

Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka.

Premaratna R, Blanton LS, Samaraweera DN, de Silva GN, Chandrasena NT, Walker DH, de Silva HJ.

BMC Infect Dis. 2017 Jan 13;17(1):67. doi: 10.1186/s12879-016-2165-z.

20.

Flea-Borne Rickettsioses and Rickettsiae.

Blanton LS, Walker DH.

Am J Trop Med Hyg. 2017 Jan 11;96(1):53-56. doi: 10.4269/ajtmh.16-0537. Epub 2016 Oct 31. Review.

21.

A phase 1 dose-escalation study of filanesib plus bortezomib and dexamethasone in patients with recurrent/refractory multiple myeloma.

Chari A, Htut M, Zonder JA, Fay JW, Jakubowiak AJ, Levy JB, Lau K, Burt SM, Tunquist BJ, Hilder BW, Rush SA, Walker DH, Ptaszynski M, Kaufman JL.

Cancer. 2016 Nov 15;122(21):3327-3335. doi: 10.1002/cncr.30174. Epub 2016 Jul 19.

22.

Scrub Typhus - Scientific Neglect, Ever-Widening Impact.

Walker DH.

N Engl J Med. 2016 Sep 8;375(10):913-5. doi: 10.1056/NEJMp1608499. No abstract available.

23.

Ehrlichioses: An Important One Health Opportunity.

Saito TB, Walker DH.

Vet Sci. 2016 Aug 31;3(3). pii: E20. doi: 10.3390/vetsci3030020. Review.

24.

An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection.

Soong L, Mendell NL, Olano JP, Rockx-Brouwer D, Xu G, Goez-Rivillas Y, Drom C, Shelite TR, Valbuena G, Walker DH, Bouyer DH.

PLoS Negl Trop Dis. 2016 Aug 1;10(8):e0004884. doi: 10.1371/journal.pntd.0004884. eCollection 2016 Aug.

25.

Rickettsia australis Activates Inflammasome in Human and Murine Macrophages.

Smalley C, Bechelli J, Rockx-Brouwer D, Saito T, Azar SR, Ismail N, Walker DH, Fang R.

PLoS One. 2016 Jun 30;11(6):e0157231. doi: 10.1371/journal.pone.0157231. eCollection 2016.

26.

Opossums and Cat Fleas: New Insights in the Ecology of Murine Typhus in Galveston, Texas.

Blanton LS, Idowu BM, Tatsch TN, Henderson JM, Bouyer DH, Walker DH.

Am J Trop Med Hyg. 2016 Aug 3;95(2):457-61. doi: 10.4269/ajtmh.16-0197. Epub 2016 Jun 6.

27.

Fatal Monocytic Ehrlichiosis in Woman, Mexico, 2013.

Sosa-Gutierrez CG, Solorzano-Santos F, Walker DH, Torres J, Serrano CA, Gordillo-Perez G.

Emerg Infect Dis. 2016 May;22(5):871-4. doi: 10.3201/eid2205.151217.

28.

MyD88 Mediates Instructive Signaling in Dendritic Cells and Protective Inflammatory Response during Rickettsial Infection.

Bechelli J, Smalley C, Zhao X, Judy B, Valdes P, Walker DH, Fang R.

Infect Immun. 2016 Mar 24;84(4):883-93. doi: 10.1128/IAI.01361-15. Print 2016 Apr.

29.

Value of Autopsy Emphasized in the Case Report of a Single Patient with Middle East Respiratory Syndrome.

Walker DH.

Am J Pathol. 2016 Mar;186(3):507-10. doi: 10.1016/j.ajpath.2015.11.001. Epub 2015 Dec 24.

PMID:
26724388
30.
31.

Changing Dynamics of Human-Rickettsial Interactions.

Walker DH.

Am J Trop Med Hyg. 2016 Jan;94(1):3-4. doi: 10.4269/ajtmh.15-0762. Epub 2015 Nov 10. No abstract available.

32.

An Unusual Cutaneous Manifestation in a Patient with Murine Typhus.

Blanton LS, Lea AS, Kelly BC, Walker DH.

Am J Trop Med Hyg. 2015 Dec;93(6):1164-7. doi: 10.4269/ajtmh.15-0380. Epub 2015 Sep 28.

33.

Rickettsia massiliae and Rickettsia conorii Israeli Spotted Fever Strain Differentially Regulate Endothelial Cell Responses.

Bechelli J, Smalley C, Milhano N, Walker DH, Fang R.

PLoS One. 2015 Sep 22;10(9):e0138830. doi: 10.1371/journal.pone.0138830. eCollection 2015.

34.

Permissive and protective roles for neutrophils in leishmaniasis.

Carlsen ED, Liang Y, Shelite TR, Walker DH, Melby PC, Soong L.

Clin Exp Immunol. 2015 Nov;182(2):109-18. doi: 10.1111/cei.12674. Epub 2015 Aug 28. Review.

35.

The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice.

Milhano N, Saito TB, Bechelli J, Fang R, Vilhena M, DE Sousa R, Walker DH.

Med Vet Entomol. 2015 Sep;29(3):225-9. doi: 10.1111/mve.12118. Epub 2015 May 26.

PMID:
26011701
36.

The role of CD8 T lymphocytes in rickettsial infections.

Walker DH, Dumler JS.

Semin Immunopathol. 2015 May;37(3):289-99. doi: 10.1007/s00281-015-0480-x. Epub 2015 Apr 1. Review.

37.

A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis.

Saito TB, Walker DH.

J Infect Dis. 2015 Sep 15;212(6):968-77. doi: 10.1093/infdis/jiv134. Epub 2015 Mar 3.

38.

Reemergence of murine typhus in Galveston, Texas, USA, 2013.

Blanton LS, Vohra RF, Bouyer DH, Walker DH.

Emerg Infect Dis. 2015 Mar;21(3):484-6. doi: 10.3201/eid2103.140716.

39.

Inactivation of SAM-methyltransferase is the mechanism of attenuation of a historic louse borne typhus vaccine strain.

Liu Y, Wu B, Weinstock G, Walker DH, Yu XJ.

PLoS One. 2014 Nov 20;9(11):e113285. doi: 10.1371/journal.pone.0113285. eCollection 2014.

40.

Rickettsia felis and changing paradigms about pathogenic rickettsiae.

Labruna MB, Walker DH.

Emerg Infect Dis. 2014 Oct;20(10):1768-9. doi: 10.3201/eid2010.131797. No abstract available.

41.

Strong type 1, but impaired type 2, immune responses contribute to Orientia tsutsugamushi-induced pathology in mice.

Soong L, Wang H, Shelite TR, Liang Y, Mendell NL, Sun J, Gong B, Valbuena GA, Bouyer DH, Walker DH.

PLoS Negl Trop Dis. 2014 Sep 25;8(9):e3191. doi: 10.1371/journal.pntd.0003191. eCollection 2014 Sep.

42.

Quantitative study of Rickettsia massiliae in Rhipicephalus sanguineus organs.

Milhano N, Popov V, Vilhena M, Bouyer DH, de Sousa R, Walker DH.

Ticks Tick Borne Dis. 2014 Oct;5(6):709-14. doi: 10.1016/j.ttbdis.2014.05.009. Epub 2014 Aug 6.

PMID:
25108779
43.

"Rickettsia amblyommii" induces cross protection against lethal Rocky Mountain spotted fever in a guinea pig model.

Blanton LS, Mendell NL, Walker DH, Bouyer DH.

Vector Borne Zoonotic Dis. 2014 Aug;14(8):557-62. doi: 10.1089/vbz.2014.1575.

PMID:
25072985
44.

Hematogenously disseminated Orientia tsutsugamushi-infected murine model of scrub typhus [corrected].

Shelite TR, Saito TB, Mendell NL, Gong B, Xu G, Soong L, Valbuena G, Bouyer DH, Walker DH.

PLoS Negl Trop Dis. 2014 Jul 10;8(7):e2966. doi: 10.1371/journal.pntd.0002966. eCollection 2014 Jul. Erratum in: PLoS Negl Trop Dis. 2014 Aug;8(8):e3175.

45.

An animal model of a newly emerging human ehrlichiosis.

Saito TB, Thirumalapura NR, Shelite TR, Rockx-Brouwer D, Popov VL, Walker DH.

J Infect Dis. 2015 Feb 1;211(3):452-61. doi: 10.1093/infdis/jiu372. Epub 2014 Jul 2. Erratum in: J Infect Dis. 2015 Jun 15;211(12):2025.

46.

After malaria is controlled, what's next?

Walker DH.

Am J Trop Med Hyg. 2014 Jul;91(1):7-10. doi: 10.4269/ajtmh.14-0056. Epub 2014 Mar 3. No abstract available.

47.

Rickettsiae and ehrlichiae within a city park: is the urban dweller at risk?

Blanton LS, Walker DH, Bouyer DH.

Vector Borne Zoonotic Dis. 2014 Feb;14(2):168-70. doi: 10.1089/vbz.2013.1473.

PMID:
24528097
48.

Complete Genome Sequence of Ehrlichia muris Strain AS145T, a Model Monocytotropic Ehrlichia Strain.

Thirumalapura NR, Qin X, Kuriakose JA, Walker DH.

Genome Announc. 2014 Jan 30;2(1). pii: e01234-13. doi: 10.1128/genomeA.01234-13.

49.
50.

Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses.

Gong B, Shelite T, Mei FC, Ha T, Hu Y, Xu G, Chang Q, Wakamiya M, Ksiazek TG, Boor PJ, Bouyer DH, Popov VL, Chen J, Walker DH, Cheng X.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19615-20. doi: 10.1073/pnas.1314400110. Epub 2013 Nov 11.

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