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Items: 1 to 50 of 395

1.

Nanopore metagenomic sequencing to investigate nosocomial transmission of human metapneumovirus from a unique genetic group among haematology patients in the United Kingdom.

Xu Y, Lewandowski K, Jeffery K, Downs LO, Foster D, Sanderson ND, Kavanagh J, Vaughan A, Salvagno C, Vipond R, Carroll M, Danby R, Peto T, Crook D, Walker AS, Matthews PC, Pullan ST.

J Infect. 2020 Feb 21. pii: S0163-4453(20)30085-2. doi: 10.1016/j.jinf.2020.02.003. [Epub ahead of print]

PMID:
32092386
2.

First Field Release of a Genetically Engineered, Self-Limiting Agricultural Pest Insect: Evaluating Its Potential for Future Crop Protection.

Shelton AM, Long SJ, Walker AS, Bolton M, Collins HL, Revuelta L, Johnson LM, Morrison NI.

Front Bioeng Biotechnol. 2020 Jan 29;7:482. doi: 10.3389/fbioe.2019.00482. eCollection 2019.

3.

Evaluation of the Coverage of 3 Antibiotic Regimens for Neonatal Sepsis in the Hospital Setting Across Asian Countries.

Bielicki JA, Sharland M, Heath PT, Walker AS, Agarwal R, Turner P, Cromwell DA.

JAMA Netw Open. 2020 Feb 5;3(2):e1921124. doi: 10.1001/jamanetworkopen.2019.21124.

4.

Handling an uncertain control group event risk in non-inferiority trials: non-inferiority frontiers and the power-stabilising transformation.

Quartagno M, Walker AS, Babiker AG, Turner RM, Parmar MKB, Copas A, White IR.

Trials. 2020 Feb 6;21(1):145. doi: 10.1186/s13063-020-4070-4.

5.

Genomic diversity affects the accuracy of bacterial single-nucleotide polymorphism-calling pipelines.

Bush SJ, Foster D, Eyre DW, Clark EL, De Maio N, Shaw LP, Stoesser N, Peto TEA, Crook DW, Walker AS.

Gigascience. 2020 Feb 1;9(2). pii: giaa007. doi: 10.1093/gigascience/giaa007.

6.

Laccases 2 & 3 as biomarkers of Botrytis cinerea infection in sweet white wines.

Ployon S, Attina A, Vialaret J, Walker AS, Hirtz C, Saucier C.

Food Chem. 2020 Jun 15;315:126233. doi: 10.1016/j.foodchem.2020.126233. Epub 2020 Jan 20.

PMID:
32018078
7.

Genomic dynamics of species and mobile genetic elements in a prolonged blaIMP-4-associated carbapenemase outbreak in an Australian hospital.

Kizny Gordon A, Phan HTT, Lipworth SI, Cheong E, Gottlieb T, George S, Peto TEA, Mathers AJ, Walker AS, Crook DW, Stoesser N.

J Antimicrob Chemother. 2020 Jan 20. pii: dkz526. doi: 10.1093/jac/dkz526. [Epub ahead of print]

PMID:
31960024
8.

Risk factors for Klebsiella pneumoniae carbapenemase (KPC) gene acquisition and clinical outcomes across multiple bacterial species.

Mathers AJ, Vegesana K, Mesner IG, Ainsworth J, Pannone A, Crook DW, Sifri CD, Sheppard A, Stoesser N, Peto T, Walker AS, Eyre DW.

J Hosp Infect. 2020 Jan 10. pii: S0195-6701(20)30007-4. doi: 10.1016/j.jhin.2020.01.005. [Epub ahead of print]

9.

Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A.

Reisberg SH, Gao Y, Walker AS, Helfrich EJN, Clardy J, Baran PS.

Science. 2020 Jan 24;367(6476):458-463. doi: 10.1126/science.aay9981. Epub 2020 Jan 2.

PMID:
31896661
10.

Standardising neonatal and paediatric antibiotic clinical trial design and conduct: the PENTA-ID network view.

Folgori L, Lutsar I, Standing JF, Walker AS, Roilides E, Zaoutis TE, Jafri H, Giaquinto C, Turner MA, Sharland M.

BMJ Open. 2019 Dec 31;9(12):e032592. doi: 10.1136/bmjopen-2019-032592.

11.

Mortality risk over time after early fluid resuscitation in African children.

George EC, Kiguli S, Olupot PO, Opoka RO, Engoru C, Akech SO, Nyeko R, Mtove G, Mpoya A, Thomason MJ, Crawley J, Evans JA, Gibb DM, Babiker AG, Maitland K, Walker AS.

Crit Care. 2019 Nov 27;23(1):377. doi: 10.1186/s13054-019-2619-y.

12.

Changes over time in creatinine clearance and comparison of emergent adverse events for HIV-positive adults receiving standard doses (300 mg/day) of lamivudine-containing antiretroviral therapy with baseline creatinine clearance of 30-49 vs ≥50 mL/min.

Ross LL, Walker AS, Lou Y, Tenorio AR, Gibb DM, Double J, Gilks C, McCoig CC, Munderi P, Musoro G, Kityo CM, Grosskurth H, Hakim J, Mugyenyi PN, Cutrell A, Perger T, Shaefer MS.

PLoS One. 2019 Nov 14;14(11):e0225199. doi: 10.1371/journal.pone.0225199. eCollection 2019.

13.

Selective culture enrichment and sequencing of feces to enhance detection of antimicrobial resistance genes in third-generation cephalosporin resistant Enterobacteriaceae.

Peto L, Fawcett NJ, Crook DW, Peto TEA, Llewelyn MJ, Walker AS.

PLoS One. 2019 Nov 8;14(11):e0222831. doi: 10.1371/journal.pone.0222831. eCollection 2019.

14.

Hash-Based Core Genome Multilocus Sequence Typing for Clostridium difficile.

Eyre DW, Peto TEA, Crook DW, Walker AS, Wilcox MH.

J Clin Microbiol. 2019 Dec 23;58(1). pii: e01037-19. doi: 10.1128/JCM.01037-19. Print 2019 Dec 23.

15.

Metagenomic Nanopore Sequencing of Influenza Virus Direct from Clinical Respiratory Samples.

Lewandowski K, Xu Y, Pullan ST, Lumley SF, Foster D, Sanderson N, Vaughan A, Morgan M, Bright N, Kavanagh J, Vipond R, Carroll M, Marriott AC, Gooch KE, Andersson M, Jeffery K, Peto TEA, Crook DW, Walker AS, Matthews PC.

J Clin Microbiol. 2019 Dec 23;58(1). pii: e00963-19. doi: 10.1128/JCM.00963-19. Print 2019 Dec 23.

16.

Transfusion Timing and Volume in African Children with Severe Anemia. Reply.

Maitland K, Olupot-Olupot P, Walker AS.

N Engl J Med. 2019 Oct 24;381(17):1687-1688. doi: 10.1056/NEJMc1911668. No abstract available.

PMID:
31644854
17.

The polyphagous plant pathogenic fungus Botrytis cinerea encompasses host-specialized and generalist populations.

Mercier A, Carpentier F, Duplaix C, Auger A, Pradier JM, Viaud M, Gladieux P, Walker AS.

Environ Microbiol. 2019 Dec;21(12):4808-4821. doi: 10.1111/1462-2920.14829. Epub 2019 Nov 3.

PMID:
31608584
18.

Co-trimoxazole or multivitamin multimineral supplement for post-discharge outcomes after severe anaemia in African children: a randomised controlled trial.

Maitland K, Olupot-Olupot P, Kiguli S, Chagaluka G, Alaroker F, Opoka RO, Mpoya A, Walsh K, Engoru C, Nteziyaremye J, Mallewa M, Kennedy N, Nakuya M, Namayanja C, Kayaga J, Nabawanuka E, Sennyondo T, Aromut D, Kumwenda F, Musika CW, Thomason MJ, Bates I, von Hensbroek MB, Evans JA, Uyoga S, Williams TN, Frost G, George EC, Gibb DM, Walker AS; TRACT trial group.

Lancet Glob Health. 2019 Oct;7(10):e1435-e1447. doi: 10.1016/S2214-109X(19)30345-6.

19.

Optimizing design of research to evaluate antibiotic stewardship interventions: consensus recommendations of a multinational working group.

Schweitzer VA, van Werkhoven CH, Rodríguez Baño J, Bielicki J, Harbarth S, Hulscher M, Huttner B, Islam J, Little P, Pulcini C, Savoldi A, Tacconelli E, Timsit JF, van Smeden M, Wolkewitz M, Bonten MJM, Walker AS, Llewelyn MJ; Joint Programming Initiative on Antimicrobial Resistance (JPIAMR) Working Group on Design of Antimicrobial Stewardship Evaluations.

Clin Microbiol Infect. 2020 Jan;26(1):41-50. doi: 10.1016/j.cmi.2019.08.017. Epub 2019 Sep 4.

20.

Comparison of long-read sequencing technologies in the hybrid assembly of complex bacterial genomes.

De Maio N, Shaw LP, Hubbard A, George S, Sanderson ND, Swann J, Wick R, AbuOun M, Stubberfield E, Hoosdally SJ, Crook DW, Peto TEA, Sheppard AE, Bailey MJ, Read DS, Anjum MF, Walker AS, Stoesser N, On Behalf Of The Rehab Consortium.

Microb Genom. 2019 Sep;5(9). doi: 10.1099/mgen.0.000294. Epub 2019 Aug 30.

21.

'Caveat emptor': the cautionary tale of endocarditis and the potential pitfalls of clinical coding data-an electronic health records study.

Fawcett N, Young B, Peto L, Quan TP, Gillott R, Wu J, Middlemass C, Weston S, Crook DW, Peto TEA, Muller-Pebody B, Johnson AP, Walker AS, Sandoe JAT.

BMC Med. 2019 Sep 4;17(1):169. doi: 10.1186/s12916-019-1390-x.

22.

Intervention planning for Antibiotic Review Kit (ARK): a digital and behavioural intervention to safely review and reduce antibiotic prescriptions in acute and general medicine.

Santillo M, Sivyer K, Krusche A, Mowbray F, Jones N, Peto TEA, Walker AS, Llewelyn MJ, Yardley L; ARK-Hospital .

J Antimicrob Chemother. 2019 Nov 1;74(11):3362-3370. doi: 10.1093/jac/dkz333.

23.

Predictors of recurrence, early treatment failure and death from Staphylococcus aureus bacteraemia: Observational analyses within the ARREST trial.

Szubert A, Bailey SL, Cooke GS, Peto T, Llewelyn MJ, Edgeworth JD, Walker AS, Thwaites GE; United Kingdom Clinical Infection Research Group (UKCIRG).

J Infect. 2019 Oct;79(4):332-340. doi: 10.1016/j.jinf.2019.08.001. Epub 2019 Aug 6.

24.

Adaptation and implementation of the ARK (Antibiotic Review Kit) intervention to safely and substantially reduce antibiotic use in hospitals: a feasibility study.

Cross ELA, Sivyer K, Islam J, Santillo M, Mowbray F, Peto TEA, Walker AS, Yardley L, Llewelyn MJ.

J Hosp Infect. 2019 Nov;103(3):268-275. doi: 10.1016/j.jhin.2019.07.017. Epub 2019 Aug 5.

PMID:
31394146
25.

Examining Utility of Routine Splenic Flexure Mobilization during Colectomy and Impact on Anastomotic Complications.

Dilday JC, Gilligan TC, Merritt CM, Nelson DW, Walker AS.

Am J Surg. 2019 Jul 25. pii: S0002-9610(19)30807-4. doi: 10.1016/j.amjsurg.2019.07.030. [Epub ahead of print]

PMID:
31375246
26.

Oral versus intravenous antibiotics for bone and joint infections: the OVIVA non-inferiority RCT.

Scarborough M, Li HK, Rombach I, Zambellas R, Walker AS, McNally M, Atkins B, Kümin M, Lipsky BA, Hughes H, Bose D, Warren S, Mack D, Folb J, Moore E, Jenkins N, Hopkins S, Seaton RA, Hemsley C, Sandoe J, Aggarwal I, Ellis S, Sutherland R, Geue C, McMeekin N, Scarborough C, Paul J, Cooke G, Bostock J, Khatamzas E, Wong N, Brent A, Lomas J, Matthews P, Wangrangsimakul T, Gundle R, Rogers M, Taylor A, Thwaites GE, Bejon P.

Health Technol Assess. 2019 Aug;23(38):1-92. doi: 10.3310/hta23380.

27.

Transfusion Volume for Children with Severe Anemia in Africa.

Maitland K, Olupot-Olupot P, Kiguli S, Chagaluka G, Alaroker F, Opoka RO, Mpoya A, Engoru C, Nteziyaremye J, Mallewa M, Kennedy N, Nakuya M, Namayanja C, Kayaga J, Uyoga S, Kyeyune Byabazaire D, M'baya B, Wabwire B, Frost G, Bates I, Evans JA, Williams TN, Saramago Goncalves P, George EC, Gibb DM, Walker AS; TRACT Group.

N Engl J Med. 2019 Aug 1;381(5):420-431. doi: 10.1056/NEJMoa1900100.

PMID:
31365800
28.

Immediate Transfusion in African Children with Uncomplicated Severe Anemia.

Maitland K, Kiguli S, Olupot-Olupot P, Engoru C, Mallewa M, Saramago Goncalves P, Opoka RO, Mpoya A, Alaroker F, Nteziyaremye J, Chagaluka G, Kennedy N, Nabawanuka E, Nakuya M, Namayanja C, Uyoga S, Kyeyune Byabazaire D, M'baya B, Wabwire B, Frost G, Bates I, Evans JA, Williams TN, George EC, Gibb DM, Walker AS; TRACT Group.

N Engl J Med. 2019 Aug 1;381(5):407-419. doi: 10.1056/NEJMoa1900105.

PMID:
31365799
29.

Using hospital network-based surveillance for antimicrobial resistance as a more robust alternative to self-reporting.

Donker T, Smieszek T, Henderson KL, Walker TM, Hope R, Johnson AP, Woodford N, Crook DW, Peto TEA, Walker AS, Robotham JV.

PLoS One. 2019 Jul 25;14(7):e0219994. doi: 10.1371/journal.pone.0219994. eCollection 2019.

30.

Antibiotic Review Kit for Hospitals (ARK-Hospital): study protocol for a stepped-wedge cluster-randomised controlled trial.

Walker AS, Budgell E, Laskawiec-Szkonter M, Sivyer K, Wordsworth S, Quaddy J, Santillo M, Krusche A, Roope LSJ, Bright N, Mowbray F, Jones N, Hand K, Rahman N, Dobson M, Hedley E, Crook D, Sharland M, Roseveare C, Hobbs FDR, Butler C, Vaughan L, Hopkins S, Yardley L, Peto TEA, Llewelyn MJ; ARK trial team.

Trials. 2019 Jul 11;20(1):421. doi: 10.1186/s13063-019-3497-y.

31.

Protocol of a two arm randomised, multi-centre, 12-month controlled trial: evaluating the impact of a Cognitive Behavioural Therapy (CBT)-based intervention Supporting UPtake and Adherence to antiretrovirals (SUPA) in adults with HIV.

Horne R, Glendinning E, King K, Chalder T, Sabin C, Walker AS, Campbell LJ, Mosweu I, Anderson J, Collins S, Jopling R, McCrone P, Leake Date H, Michie S, Nelson M, Perry N, Smith JA, Sseruma W, Cooper V; SUPA Group.

BMC Public Health. 2019 Jul 8;19(1):905. doi: 10.1186/s12889-019-6893-z.

32.

Optimising trial designs to identify appropriate antibiotic treatment durations.

Pouwels KB, Yin M, Butler CC, Cooper BS, Wordsworth S, Walker AS, Robotham JV.

BMC Med. 2019 Jun 21;17(1):115. doi: 10.1186/s12916-019-1348-z.

33.

Mapping the medical outcomes study HIV health survey (MOS-HIV) to the EuroQoL 5 Dimension (EQ-5D-3 L) utility index.

Shi Y, Thompson J, Walker AS, Paton NI, Cheung YB; EARNEST Trial Team.

Health Qual Life Outcomes. 2019 May 10;17(1):83. doi: 10.1186/s12955-019-1135-8.

34.

Clostridium difficile trehalose metabolism variants are common and not associated with adverse patient outcomes when variably present in the same lineage.

Eyre DW, Didelot X, Buckley AM, Freeman J, Moura IB, Crook DW, Peto TEA, Walker AS, Wilcox MH, Dingle KE.

EBioMedicine. 2019 May;43:347-355. doi: 10.1016/j.ebiom.2019.04.038. Epub 2019 Apr 27.

35.

Inflammatory biomarkers in HIV-infected children hospitalized for severe malnutrition in Uganda and Zimbabwe.

Prendergast AJ, Berejena C, Pimundu G, Shonhai A, Bwakura-Dangarembizi M, Musiime V, Szubert AJ, Cook AD, Spyer MJ, Nahirya-Ntege P, Kekitiinwa A, Gibb DM, Klein N, Walker AS.

AIDS. 2019 Jul 15;33(9):1485-1490. doi: 10.1097/QAD.0000000000002231.

PMID:
31008797
36.

Dissemination of multiple carbapenem resistance genes in an in vitro gut model simulating the human colon.

Rooney CM, Sheppard AE, Clark E, Davies K, Hubbard ATM, Sebra R, Crook DW, Walker AS, Wilcox MH, Chilton CH.

J Antimicrob Chemother. 2019 Jul 1;74(7):1876-1883. doi: 10.1093/jac/dkz106.

PMID:
30989197
37.

The application of self-limiting transgenic insects in managing resistance in experimental metapopulations.

Zhou L, Alphey N, Walker AS, Travers LM, Morrison NI, Bonsall MB, Raymond B.

J Appl Ecol. 2019 Mar;56(3):688-698. doi: 10.1111/1365-2664.13298. Epub 2018 Nov 24.

38.

The challenge of antimicrobial resistance: What economics can contribute.

Roope LSJ, Smith RD, Pouwels KB, Buchanan J, Abel L, Eibich P, Butler CC, Tan PS, Walker AS, Robotham JV, Wordsworth S.

Science. 2019 Apr 5;364(6435). pii: eaau4679. doi: 10.1126/science.aau4679. Review.

PMID:
30948524
39.

Cotrimoxazole reduces systemic inflammation in HIV infection by altering the gut microbiome and immune activation.

Bourke CD, Gough EK, Pimundu G, Shonhai A, Berejena C, Terry L, Baumard L, Choudhry N, Karmali Y, Bwakura-Dangarembizi M, Musiime V, Lutaakome J, Kekitiinwa A, Mutasa K, Szubert AJ, Spyer MJ, Deayton JR, Glass M, Geum HM, Pardieu C, Gibb DM, Klein N, Edens TJ, Walker AS, Manges AR, Prendergast AJ.

Sci Transl Med. 2019 Apr 3;11(486). pii: eaav0537. doi: 10.1126/scitranslmed.aav0537.

40.

Klebsiella quasipneumoniae Provides a Window into Carbapenemase Gene Transfer, Plasmid Rearrangements, and Patient Interactions with the Hospital Environment.

Mathers AJ, Crook D, Vaughan A, Barry KE, Vegesana K, Stoesser N, Parikh HI, Sebra R, Kotay S, Walker AS, Sheppard AE.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e02513-18. doi: 10.1128/AAC.02513-18. Print 2019 Jun.

41.

Modelling microbiome recovery after antibiotics using a stability landscape framework.

Shaw LP, Bassam H, Barnes CP, Walker AS, Klein N, Balloux F.

ISME J. 2019 Jul;13(7):1845-1856. doi: 10.1038/s41396-019-0392-1. Epub 2019 Mar 15.

42.

Epidemiology of paediatric gastrointestinal colonisation by extended spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolates in north-west Cambodia.

van Aartsen JJ, Moore CE, Parry CM, Turner P, Phot N, Mao S, Suy K, Davies T, Giess A, Sheppard AE, Peto TEA, Day NPJ, Crook DW, Walker AS, Stoesser N.

BMC Microbiol. 2019 Mar 12;19(1):59. doi: 10.1186/s12866-019-1431-9.

43.

A Role for Tetracycline Selection in Recent Evolution of Agriculture-Associated Clostridium difficile PCR Ribotype 078.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Marwick CA, Coia J, Brown D, Buchanan S, Ijaz UZ, Goswami C, Douce G, Fawley WN, Wilcox MH, Peto TEA, Walker AS, Crook DW.

mBio. 2019 Mar 12;10(2). pii: e02790-18. doi: 10.1128/mBio.02790-18.

44.

Haematological quality and age of donor blood issued for paediatric transfusion to four hospitals in sub-Saharan Africa.

Uyoga S, Mpoya A, Olupot-Olupot P, Kiguli S, Opoka RO, Engoru C, Mallewa M, Kennedy N, M'baya B, Kyeyune D, Wabwire B, Bates I, Gibb DM, Walker AS, George EC, Williams TN, Maitland K.

Vox Sang. 2019 May;114(4):340-348. doi: 10.1111/vox.12764. Epub 2019 Mar 5.

45.

Duration of antibiotic treatment for common infections in English primary care: cross sectional analysis and comparison with guidelines.

Pouwels KB, Hopkins S, Llewelyn MJ, Walker AS, McNulty CA, Robotham JV.

BMJ. 2019 Feb 27;364:l440. doi: 10.1136/bmj.l440.

46.

Health Outcomes, Pathogenesis and Epidemiology of Severe Acute Malnutrition (HOPE-SAM): rationale and methods of a longitudinal observational study.

Bwakura-Dangarembizi M, Amadi B, Bourke CD, Robertson RC, Mwapenya B, Chandwe K, Kapoma C, Chifunda K, Majo F, Ngosa D, Chakara P, Chulu N, Masimba F, Mapurisa I, Besa E, Mutasa K, Mwakamui S, Runodamoto T, Humphrey JH, Ntozini R, Wells JCK, Manges AR, Swann JR, Walker AS, Nathoo KJ, Kelly P, Prendergast AJ; HOPE-SAM study team.

BMJ Open. 2019 Feb 1;9(1):e023077. doi: 10.1136/bmjopen-2018-023077.

47.

Oral versus Intravenous Antibiotics for Bone and Joint Infection.

Li HK, Rombach I, Zambellas R, Walker AS, McNally MA, Atkins BL, Lipsky BA, Hughes HC, Bose D, Kümin M, Scarborough C, Matthews PC, Brent AJ, Lomas J, Gundle R, Rogers M, Taylor A, Angus B, Byren I, Berendt AR, Warren S, Fitzgerald FE, Mack DJF, Hopkins S, Folb J, Reynolds HE, Moore E, Marshall J, Jenkins N, Moran CE, Woodhouse AF, Stafford S, Seaton RA, Vallance C, Hemsley CJ, Bisnauthsing K, Sandoe JAT, Aggarwal I, Ellis SC, Bunn DJ, Sutherland RK, Barlow G, Cooper C, Geue C, McMeekin N, Briggs AH, Sendi P, Khatamzas E, Wangrangsimakul T, Wong THN, Barrett LK, Alvand A, Old CF, Bostock J, Paul J, Cooke G, Thwaites GE, Bejon P, Scarborough M; OVIVA Trial Collaborators.

N Engl J Med. 2019 Jan 31;380(5):425-436. doi: 10.1056/NEJMoa1710926.

48.

DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis.

Yang Y, Walker TM, Walker AS, Wilson DJ, Peto TEA, Crook DW, Shamout F; CRyPTIC Consortium , Zhu T, Clifton DA.

Bioinformatics. 2019 Sep 15;35(18):3240-3249. doi: 10.1093/bioinformatics/btz067.

49.

Spatiotemporal dynamics of fungicide resistance in the wheat pathogen Zymoseptoria tritici in France.

Garnault M, Duplaix C, Leroux P, Couleaud G, Carpentier F, David O, Walker AS.

Pest Manag Sci. 2019 Jul;75(7):1794-1807. doi: 10.1002/ps.5360. Epub 2019 Mar 18.

PMID:
30680908
50.

Rapid antiretroviral therapy initiation in low- and middle-income countries: A resource-based approach.

Tenforde MW, Walker AS, Gibb DM, Manabe YC.

PLoS Med. 2019 Jan 15;16(1):e1002723. doi: 10.1371/journal.pmed.1002723. eCollection 2019 Jan.

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