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Items: 1 to 50 of 80

1.

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

Kim JS, He X, Liu J, Duan Z, Kim T, Gerard J, Kim B, Pillai MM, Lane WS, Noble WS, Budnik B, Waldman T.

J Biol Chem. 2019 May 31;294(22):8760-8772. doi: 10.1074/jbc.RA119.007832. Epub 2019 Apr 22.

PMID:
31010829
2.

STAG2 Is a Biomarker for Prediction of Recurrence and Progression in Papillary Non-Muscle-Invasive Bladder Cancer.

Lelo A, Prip F, Harris BT, Solomon D, Berry DL, Chaldekas K, Kumar A, Simko J, Jensen JB, Bhattacharyya P, Mannion C, Kim JS, Philips G, Dyrskjøt L, Waldman T.

Clin Cancer Res. 2018 Sep 1;24(17):4145-4153. doi: 10.1158/1078-0432.CCR-17-3244. Epub 2018 Jun 28.

3.

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts.

van der Lelij P, Lieb S, Jude J, Wutz G, Santos CP, Falkenberg K, Schlattl A, Ban J, Schwentner R, Hoffmann T, Kovar H, Real FX, Waldman T, Pearson MA, Kraut N, Peters JM, Zuber J, Petronczki M.

Elife. 2017 Jul 10;6. pii: e26980. doi: 10.7554/eLife.26980.

4.

Correction of PTEN mutations in glioblastoma cell lines via AAV-mediated gene editing.

Hill VK, Kim JS, James CD, Waldman T.

PLoS One. 2017 May 2;12(5):e0176683. doi: 10.1371/journal.pone.0176683. eCollection 2017.

5.

The Inaugural Use of Gene Editing for the Study of Tumor Suppressor Pathways in Human Cells-p21WAF1/CIP1.

Waldman T.

Cancer Res. 2016 Aug 15;76(16):4598-601. doi: 10.1158/0008-5472.CAN-16-1972. No abstract available.

6.

Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth.

Hashizume R, Zhang A, Mueller S, Prados MD, Lulla RR, Goldman S, Saratsis AM, Mazar AP, Stegh AH, Cheng SY, Horbinski C, Haas-Kogan DA, Sarkaria JN, Waldman T, James CD.

Neuro Oncol. 2016 Nov;18(11):1519-1528. Epub 2016 Jul 1.

7.

Cohesin mutations in human cancer.

Hill VK, Kim JS, Waldman T.

Biochim Biophys Acta. 2016 Aug;1866(1):1-11. doi: 10.1016/j.bbcan.2016.05.002. Epub 2016 May 17. Review.

8.

Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2.

Kim JS, He X, Orr B, Wutz G, Hill V, Peters JM, Compton DA, Waldman T.

PLoS Genet. 2016 Feb 12;12(2):e1005865. doi: 10.1371/journal.pgen.1005865. eCollection 2016 Feb.

9.

Do women with statin-related myalgias have low vitamin D levels?

Minissian M, Agarwal M, Shufelt C, Mehta PK, Waldman T, Lentz G, Cook-Wiens G, Eastwood JA, Noel Bairey Merz C.

BMC Res Notes. 2015 Sep 17;8:449. doi: 10.1186/s13104-015-1356-9.

10.

Calcium Supplements and Cardiovascular Disease: A Review.

Waldman T, Sarbaziha R, Merz CN, Shufelt C.

Am J Lifestyle Med. 2015 Jul 1;9(4):298-307.

11.

Female-specific factors for IHD: across the reproductive lifespan.

Shufelt C, Waldman T, Wang E, Merz CN.

Curr Atheroscler Rep. 2015;17(2):481. doi: 10.1007/s11883-014-0481-6. Review.

PMID:
25620277
12.

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.

Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, Fang D, Huang X, Tom MW, Ngo V, Solomon D, Mueller S, Paris PL, Zhang Z, Petritsch C, Gupta N, Waldman TA, James CD.

Nat Med. 2014 Dec;20(12):1394-6. doi: 10.1038/nm.3716. Epub 2014 Nov 17.

13.

Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma.

Walia V, Prickett TD, Kim JS, Gartner JJ, Lin JC, Zhou M, Rosenberg SA, Elble RC, Solomon DA, Waldman T, Samuels Y.

Hum Mutat. 2014 Nov;35(11):1301-10. doi: 10.1002/humu.22630. Epub 2014 Sep 10.

14.

The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.

Brohl AS, Solomon DA, Chang W, Wang J, Song Y, Sindiri S, Patidar R, Hurd L, Chen L, Shern JF, Liao H, Wen X, Gerard J, Kim JS, Lopez Guerrero JA, Machado I, Wai DH, Picci P, Triche T, Horvai AE, Miettinen M, Wei JS, Catchpool D, Llombart-Bosch A, Waldman T, Khan J.

PLoS Genet. 2014 Jul 10;10(7):e1004475. doi: 10.1371/journal.pgen.1004475. eCollection 2014 Jul. Erratum in: PLoS Genet. 2014 Aug;10(8):e1004629.

15.

Cohesin gene mutations in tumorigenesis: from discovery to clinical significance.

Solomon DA, Kim JS, Waldman T.

BMB Rep. 2014 Jun;47(6):299-310. Review.

16.

Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibition.

Bailey ML, O'Neil NJ, van Pel DM, Solomon DA, Waldman T, Hieter P.

Mol Cancer Ther. 2014 Mar;13(3):724-32. doi: 10.1158/1535-7163.MCT-13-0749. Epub 2013 Dec 19.

17.

Frequent truncating mutations of STAG2 in bladder cancer.

Solomon DA, Kim JS, Bondaruk J, Shariat SF, Wang ZF, Elkahloun AG, Ozawa T, Gerard J, Zhuang D, Zhang S, Navai N, Siefker-Radtke A, Phillips JJ, Robinson BD, Rubin MA, Volkmer B, Hautmann R, Küfer R, Hogendoorn PC, Netto G, Theodorescu D, James CD, Czerniak B, Miettinen M, Waldman T.

Nat Genet. 2013 Dec;45(12):1428-30. doi: 10.1038/ng.2800. Epub 2013 Oct 13.

18.

Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines.

Vartanian S, Bentley C, Brauer MJ, Li L, Shirasawa S, Sasazuki T, Kim JS, Haverty P, Stawiski E, Modrusan Z, Waldman T, Stokoe D.

J Biol Chem. 2013 Jan 25;288(4):2403-13. doi: 10.1074/jbc.M112.394130. Epub 2012 Nov 27.

19.

p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells.

Cen L, Carlson BL, Schroeder MA, Ostrem JL, Kitange GJ, Mladek AC, Fink SR, Decker PA, Wu W, Kim JS, Waldman T, Jenkins RB, Sarkaria JN.

Neuro Oncol. 2012 Jul;14(7):870-81. doi: 10.1093/neuonc/nos114. Epub 2012 Jun 18.

20.

Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy.

Huillard E, Hashizume R, Phillips JJ, Griveau A, Ihrie RA, Aoki Y, Nicolaides T, Perry A, Waldman T, McMahon M, Weiss WA, Petritsch C, James CD, Rowitch DH.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8710-5. doi: 10.1073/pnas.1117255109. Epub 2012 May 14.

21.

Changes in utilization and costs for patients with rheumatoid arthritis, 1997 to 2006.

Birnbaum HG, Pike C, Banerjee R, Waldman T, Cifaldi M.

Pharmacoeconomics. 2012 Apr;30(4):323-36. doi: 10.2165/11589470-000000000-00000.

PMID:
22379953
22.

Real-world role of tricyclic antidepressants in the treatment of fibromyalgia.

Reed C, Birnbaum HG, Ivanova JI, Schiller M, Waldman T, Mullen RE, Swindle R.

Pain Pract. 2012 Sep;12(7):533-40. doi: 10.1111/j.1533-2500.2011.00526.x. Epub 2012 Jan 9.

PMID:
22226400
23.

Targeted therapy for BRAFV600E malignant astrocytoma.

Nicolaides TP, Li H, Solomon DA, Hariono S, Hashizume R, Barkovich K, Baker SJ, Paugh BS, Jones C, Forshew T, Hindley GF, Hodgson JG, Kim JS, Rowitch DH, Weiss WA, Waldman TA, James CD.

Clin Cancer Res. 2011 Dec 15;17(24):7595-604. doi: 10.1158/1078-0432.CCR-11-1456. Epub 2011 Oct 28.

24.

Direct and indirect costs of patients treated with extended-release oxymorphone HCl or controlled-release oxycodone HCl.

Kirson NY, White AG, Birnbaum HG, Schiller M, Waldman T, Peterson K, Ben-Joseph RH, Berner T, Summers KH.

J Med Econ. 2012;15(1):87-95. doi: 10.3111/13696998.2011.629261. Epub 2011 Oct 28.

PMID:
22032675
25.

Excess costs associated with patients with chronic thromboembolic pulmonary hypertension in a US privately insured population.

Kirson NY, Birnbaum HG, Ivanova JI, Waldman T, Joish V, Williamson T.

Appl Health Econ Health Policy. 2011 Nov 1;9(6):377-87. doi: 10.2165/11592440-000000000-00000.

PMID:
21888449
26.

Excess costs associated with patients with pulmonary arterial hypertension in a US privately insured population.

Kirson NY, Birnbaum HG, Ivanova JI, Waldman T, Joish V, Williamson T.

Appl Health Econ Health Policy. 2011 Sep 1;9(5):293-303. doi: 10.2165/11592430-000000000-00000.

PMID:
21875160
27.

Mutational inactivation of STAG2 causes aneuploidy in human cancer.

Solomon DA, Kim T, Diaz-Martinez LA, Fair J, Elkahloun AG, Harris BT, Toretsky JA, Rosenberg SA, Shukla N, Ladanyi M, Samuels Y, James CD, Yu H, Kim JS, Waldman T.

Science. 2011 Aug 19;333(6045):1039-43. doi: 10.1126/science.1203619.

28.
29.

Prevalence of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension in the United States.

Kirson NY, Birnbaum HG, Ivanova JI, Waldman T, Joish V, Williamson T.

Curr Med Res Opin. 2011 Sep;27(9):1763-8. doi: 10.1185/03007995.2011.604310. Epub 2011 Jul 27.

PMID:
21793646
30.

Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells.

Kim JS, Xu X, Li H, Solomon D, Lane WS, Jin T, Waldman T.

Mol Cell Biol. 2011 Jul;31(13):2756-71. doi: 10.1128/MCB.01323-10. Epub 2011 May 2.

31.

Societal costs of prescription opioid abuse, dependence, and misuse in the United States.

Birnbaum HG, White AG, Schiller M, Waldman T, Cleveland JM, Roland CL.

Pain Med. 2011 Apr;12(4):657-67. doi: 10.1111/j.1526-4637.2011.01075.x. Epub 2011 Mar 10.

PMID:
21392250
32.

A high-throughput screen with isogenic PTEN+/+ and PTEN-/- cells identifies CID1340132 as a novel compound that induces apoptosis in PTEN and PIK3CA mutant human cancer cells.

Li HF, Keeton A, Vitolo M, Maddox C, Rasmussen L, Hobrath J, White EL, Park BH, Piazza GA, Kim JS, Waldman T.

J Biomol Screen. 2011 Apr;16(4):383-93. doi: 10.1177/1087057110397357. Epub 2011 Feb 18.

33.

Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes.

Duncan CG, Killela PJ, Payne CA, Lampson B, Chen WC, Liu J, Solomon D, Waldman T, Towers AJ, Gregory SG, McDonald KL, McLendon RE, Bigner DD, Yan H.

Oncotarget. 2010 Aug;1(4):265-77.

34.

IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain.

Lopez GY, Reitman ZJ, Solomon D, Waldman T, Bigner DD, McLendon RE, Rosenberg SA, Samuels Y, Yan H.

Biochem Biophys Res Commun. 2010 Jul 30;398(3):585-7. doi: 10.1016/j.bbrc.2010.06.125. Epub 2010 Jul 13.

35.

Oncogenic mutations of PIK3CA in human cancers.

Samuels Y, Waldman T.

Curr Top Microbiol Immunol. 2010;347:21-41. doi: 10.1007/82_2010_68. Review.

36.

Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.

Michaud K, Solomon DA, Oermann E, Kim JS, Zhong WZ, Prados MD, Ozawa T, James CD, Waldman T.

Cancer Res. 2010 Apr 15;70(8):3228-38. doi: 10.1158/0008-5472.CAN-09-4559. Epub 2010 Mar 30.

37.

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors.

Mendes-Pereira AM, Martin SA, Brough R, McCarthy A, Taylor JR, Kim JS, Waldman T, Lord CJ, Ashworth A.

EMBO Mol Med. 2009 Sep;1(6-7):315-22. doi: 10.1002/emmm.200900041.

38.

Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells.

Vitolo MI, Weiss MB, Szmacinski M, Tahir K, Waldman T, Park BH, Martin SS, Weber DJ, Bachman KE.

Cancer Res. 2009 Nov 1;69(21):8275-83. doi: 10.1158/0008-5472.CAN-09-1067. Epub 2009 Oct 20.

39.

Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells.

Li HF, Kim JS, Waldman T.

Radiat Oncol. 2009 Oct 14;4:43. doi: 10.1186/1748-717X-4-43.

40.

Sample type bias in the analysis of cancer genomes.

Solomon DA, Kim JS, Ressom HW, Sibenaller Z, Ryken T, Jean W, Bigner D, Yan H, Waldman T.

Cancer Res. 2009 Jul 15;69(14):5630-3. doi: 10.1158/0008-5472.CAN-09-1055. Epub 2009 Jun 30.

41.

Lack of inherited mutations of PTPRD in familial melanoma and melanoma-astrocytoma syndrome.

Solomon DA, Kim JS, Yang XR, Tucker MA, Goldstein AM, Samuels Y, Waldman T.

Pigment Cell Melanoma Res. 2009 Aug;22(4):489-91. doi: 10.1111/j.1755-148X.2009.00587.x. Epub 2009 Jun 3. No abstract available.

42.

Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma.

Solomon DA, Kim JS, Cronin JC, Sibenaller Z, Ryken T, Rosenberg SA, Ressom H, Jean W, Bigner D, Yan H, Samuels Y, Waldman T.

Cancer Res. 2008 Dec 15;68(24):10300-6. doi: 10.1158/0008-5472.CAN-08-3272.

43.

Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells.

Gabai VL, Yaglom JA, Waldman T, Sherman MY.

Mol Cell Biol. 2009 Jan;29(2):559-69. doi: 10.1128/MCB.01041-08. Epub 2008 Nov 10.

44.

Conspirators in a capital crime: co-deletion of p18INK4c and p16INK4a/p14ARF/p15INK4b in glioblastoma multiforme.

Solomon DA, Kim JS, Jean W, Waldman T.

Cancer Res. 2008 Nov 1;68(21):8657-60. doi: 10.1158/0008-5472.CAN-08-2084. Review.

45.

Epitope tagging of endogenous genes in diverse human cell lines.

Kim JS, Bonifant C, Bunz F, Lane WS, Waldman T.

Nucleic Acids Res. 2008 Nov;36(19):e127. doi: 10.1093/nar/gkn566. Epub 2008 Sep 10.

46.

Identification of p18 INK4c as a tumor suppressor gene in glioblastoma multiforme.

Solomon DA, Kim JS, Jenkins S, Ressom H, Huang M, Coppa N, Mabanta L, Bigner D, Yan H, Jean W, Waldman T.

Cancer Res. 2008 Apr 15;68(8):2564-9. doi: 10.1158/0008-5472.CAN-07-6388. Epub 2008 Apr 1.

47.

Human somatic cell gene targeting.

Waldman T, Lee C, Nishanian TG, Kim JS.

Curr Protoc Mol Biol. 2003 May;Chapter 9:Unit 9.15. doi: 10.1002/0471142727.mb0915s62.

PMID:
18265333
48.

NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN.

Bonifant CL, Kim JS, Waldman T.

J Cell Biochem. 2007 Nov 1;102(4):878-85. Review.

49.

Activated PI3K signaling as an endogenous inducer of p53 in human cancer.

Lee C, Kim JS, Waldman T.

Cell Cycle. 2007 Feb 15;6(4):394-6. Epub 2007 Feb 3.

50.

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer.

Stein U, Arlt F, Walther W, Smith J, Waldman T, Harris ED, Mertins SD, Heizmann CW, Allard D, Birchmeier W, Schlag PM, Shoemaker RH.

Gastroenterology. 2006 Nov;131(5):1486-500. Epub 2006 Aug 22.

PMID:
17101323

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