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Items: 44

1.

GPR55: Metabolic Help or Hindrance?

Henstridge CM, Brown AJ, Waldhoer M.

Trends Endocrinol Metab. 2016 Sep;27(9):606-608. doi: 10.1016/j.tem.2016.04.012. Epub 2016 May 21. Review.

PMID:
27215467
2.

Gα13 mediates human cytomegalovirus-encoded chemokine receptor US28-induced cell death in melanoma.

Joshi S, Wels C, Beham-Schmid C, Fukunaga-Kalabis M, Holmen SL, Otte M, Herlyn M, Waldhoer M, Schaider H.

Int J Cancer. 2015 Sep 15;137(6):1503-8. doi: 10.1002/ijc.29506. Epub 2015 Mar 16.

3.

Functional consequences of glucagon-like peptide-1 receptor cross-talk and trafficking.

Roed SN, Nøhr AC, Wismann P, Iversen H, Bräuner-Osborne H, Knudsen SM, Waldhoer M.

J Biol Chem. 2015 Jan 9;290(2):1233-43. doi: 10.1074/jbc.M114.592436. Epub 2014 Dec 1.

4.

Heteromerization of GPR55 and cannabinoid CB2 receptors modulates signalling.

Balenga NA, Martínez-Pinilla E, Kargl J, Schröder R, Peinhaupt M, Platzer W, Bálint Z, Zamarbide M, Dopeso-Reyes IG, Ricobaraza A, Pérez-Ortiz JM, Kostenis E, Waldhoer M, Heinemann A, Franco R.

Br J Pharmacol. 2014 Dec;171(23):5387-406. doi: 10.1111/bph.12850. Epub 2014 Sep 5.

5.

Real-time trafficking and signaling of the glucagon-like peptide-1 receptor.

Roed SN, Wismann P, Underwood CR, Kulahin N, Iversen H, Cappelen KA, Schäffer L, Lehtonen J, Hecksher-Soerensen J, Secher A, Mathiesen JM, Bräuner-Osborne H, Whistler JL, Knudsen SM, Waldhoer M.

Mol Cell Endocrinol. 2014 Feb 15;382(2):938-49. doi: 10.1016/j.mce.2013.11.010. Epub 2013 Nov 22.

6.

A selective antagonist reveals a potential role of G protein-coupled receptor 55 in platelet and endothelial cell function.

Kargl J, Brown AJ, Andersen L, Dorn G, Schicho R, Waldhoer M, Heinemann A.

J Pharmacol Exp Ther. 2013 Jul;346(1):54-66. doi: 10.1124/jpet.113.204180. Epub 2013 May 2.

PMID:
23639801
7.

The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55.

Kargl J, Balenga N, Parzmair GP, Brown AJ, Heinemann A, Waldhoer M.

J Biol Chem. 2012 Dec 28;287(53):44234-48. doi: 10.1074/jbc.M112.364109. Epub 2012 Nov 16.

8.

Human cytomegalovirus-encoded UL33 and UL78 heteromerize with host CCR5 and CXCR4 impairing their HIV coreceptor activity.

Tadagaki K, Tudor D, Gbahou F, Tschische P, Waldhoer M, Bomsel M, Jockers R, Kamal M.

Blood. 2012 May 24;119(21):4908-18. doi: 10.1182/blood-2011-08-372516. Epub 2012 Apr 10.

PMID:
22496149
9.

Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55.

Henstridge CM, Balenga NA, Kargl J, Andradas C, Brown AJ, Irving A, Sanchez C, Waldhoer M.

Mol Endocrinol. 2011 Nov;25(11):1835-48. doi: 10.1210/me.2011-1197. Epub 2011 Sep 29. Review.

10.

D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells.

Sedej M, Schröder R, Bell K, Platzer W, Vukoja A, Kostenis E, Heinemann A, Waldhoer M.

J Allergy Clin Immunol. 2012 Feb;129(2):492-500, 500.e1-9. doi: 10.1016/j.jaci.2011.08.015. Epub 2011 Sep 17.

PMID:
21930295
11.

Pharmacology, signaling and physiological relevance of the G protein-coupled receptor 55.

Balenga NA, Henstridge CM, Kargl J, Waldhoer M.

Adv Pharmacol. 2011;62:251-77. doi: 10.1016/B978-0-12-385952-5.00004-X. Review.

PMID:
21907912
12.

The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55.

Kargl J, Balenga NA, Platzer W, Martini L, Whistler JL, Waldhoer M.

Br J Pharmacol. 2012 Apr;165(8):2611-9. doi: 10.1111/j.1476-5381.2011.01562.x.

13.

Heteromerization of human cytomegalovirus encoded chemokine receptors.

Tschische P, Tadagaki K, Kamal M, Jockers R, Waldhoer M.

Biochem Pharmacol. 2011 Sep 15;82(6):610-9. doi: 10.1016/j.bcp.2011.06.009. Epub 2011 Jun 13.

14.

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils.

Balenga NA, Aflaki E, Kargl J, Platzer W, Schröder R, Blättermann S, Kostenis E, Brown AJ, Heinemann A, Waldhoer M.

Cell Res. 2011 Oct;21(10):1452-69. doi: 10.1038/cr.2011.60. Epub 2011 Apr 5. Erratum in: Cell Res. 2011 Nov;21(11):1641.

15.

G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning G protein-coupled receptors.

Moser E, Kargl J, Whistler JL, Waldhoer M, Tschische P.

Pharmacology. 2010;86(1):22-9. doi: 10.1159/000314161. Epub 2010 Jun 26. Review.

16.

CRTH2 and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases.

Schuligoi R, Sturm E, Luschnig P, Konya V, Philipose S, Sedej M, Waldhoer M, Peskar BA, Heinemann A.

Pharmacology. 2010;85(6):372-82. doi: 10.1159/000313836. Epub 2010 Jun 16. Review.

17.

GPR55 ligands promote receptor coupling to multiple signalling pathways.

Henstridge CM, Balenga NA, Schröder R, Kargl JK, Platzer W, Martini L, Arthur S, Penman J, Whistler JL, Kostenis E, Waldhoer M, Irving AJ.

Br J Pharmacol. 2010 Jun;160(3):604-14. doi: 10.1111/j.1476-5381.2009.00625.x. Epub 2010 Feb 5.

18.

The G-protein coupled receptor associated sorting protein GASP-1 regulates the signalling and trafficking of the viral chemokine receptor US28.

Tschische P, Moser E, Thompson D, Vischer HF, Parzmair GP, Pommer V, Platzer W, Schwarzbraun T, Schaider H, Smit MJ, Martini L, Whistler JL, Waldhoer M.

Traffic. 2010 May;11(5):660-74. doi: 10.1111/j.1600-0854.2010.1045.x.

19.

Opioid-receptor-heteromer-specific trafficking and pharmacology.

van Rijn RM, Whistler JL, Waldhoer M.

Curr Opin Pharmacol. 2010 Feb;10(1):73-9. doi: 10.1016/j.coph.2009.09.007. Epub 2009 Oct 19. Review.

20.

Building a new conceptual framework for receptor heteromers.

Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, Waldhoer M, Woods AS, Franco R.

Nat Chem Biol. 2009 Mar;5(3):131-4. doi: 10.1038/nchembio0309-131.

21.

A membrane network of receptors and enzymes for adenine nucleotides and nucleosides.

Schicker K, Hussl S, Chandaka GK, Kosenburger K, Yang JW, Waldhoer M, Sitte HH, Boehm S.

Biochim Biophys Acta. 2009 Feb;1793(2):325-34. doi: 10.1016/j.bbamcr.2008.09.014. Epub 2008 Oct 10.

22.

Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.

Schuligoi R, Sedej M, Waldhoer M, Vukoja A, Sturm EM, Lippe IT, Peskar BA, Heinemann A.

J Leukoc Biol. 2009 Jan;85(1):136-45. doi: 10.1189/jlb.0608387. Epub 2008 Oct 3.

PMID:
18835884
23.

The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation.

Henstridge CM, Balenga NA, Ford LA, Ross RA, Waldhoer M, Irving AJ.

FASEB J. 2009 Jan;23(1):183-93. doi: 10.1096/fj.08-108670. Epub 2008 Aug 29.

PMID:
18757503
24.

Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression.

Waldeck-Weiermair M, Zoratti C, Osibow K, Balenga N, Goessnitzer E, Waldhoer M, Malli R, Graier WF.

J Cell Sci. 2008 May 15;121(Pt 10):1704-1717. doi: 10.1242/jcs.020958. Epub 2008 Apr 29.

25.

Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence.

Kim JA, Bartlett S, He L, Nielsen CK, Chang AM, Kharazia V, Waldhoer M, Ou CJ, Taylor S, Ferwerda M, Cado D, Whistler JL.

Curr Biol. 2008 Jan 22;18(2):129-35. doi: 10.1016/j.cub.2007.12.057.

26.

Structure, function and physiological consequences of virally encoded chemokine seven transmembrane receptors.

Rosenkilde MM, Smit MJ, Waldhoer M.

Br J Pharmacol. 2008 Mar;153 Suppl 1:S154-66. doi: 10.1038/sj.bjp.0707660. Epub 2008 Jan 21. Review.

27.

The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking.

Schratl P, Royer JF, Kostenis E, Ulven T, Sturm EM, Waldhoer M, Hoefler G, Schuligoi R, Lippe IT, Peskar BA, Heinemann A.

J Immunol. 2007 Oct 1;179(7):4792-9.

28.

Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1.

Martini L, Waldhoer M, Pusch M, Kharazia V, Fong J, Lee JH, Freissmuth C, Whistler JL.

FASEB J. 2007 Mar;21(3):802-11. Epub 2006 Dec 28.

PMID:
17197383
29.

Dopamine responsiveness is regulated by targeted sorting of D2 receptors.

Bartlett SE, Enquist J, Hopf FW, Lee JH, Gladher F, Kharazia V, Waldhoer M, Mailliard WS, Armstrong R, Bonci A, Whistler JL.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11521-6. Epub 2005 Jul 27.

30.

A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers.

Waldhoer M, Fong J, Jones RM, Lunzer MM, Sharma SK, Kostenis E, Portoghese PS, Whistler JL.

Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):9050-5. Epub 2005 Jun 2.

31.

A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity.

Kostenis E, Martini L, Ellis J, Waldhoer M, Heydorn A, Rosenkilde MM, Norregaard PK, Jorgensen R, Whistler JL, Milligan G.

J Pharmacol Exp Ther. 2005 Apr;313(1):78-87. Epub 2004 Dec 22.

PMID:
15615862
32.

CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor.

Casarosa P, Waldhoer M, LiWang PJ, Vischer HF, Kledal T, Timmerman H, Schwartz TW, Smit MJ, Leurs R.

J Biol Chem. 2005 Feb 4;280(5):3275-85. Epub 2004 Nov 16.

33.

Opioid receptors.

Waldhoer M, Bartlett SE, Whistler JL.

Annu Rev Biochem. 2004;73:953-90. Review.

PMID:
15189164
34.
35.

The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis.

Waldhoer M, Casarosa P, Rosenkilde MM, Smit MJ, Leurs R, Whistler JL, Schwartz TW.

J Biol Chem. 2003 May 23;278(21):19473-82. Epub 2003 Mar 18.

36.
37.

Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain.

Kudlacek O, Waldhoer M, Kassack MU, Nickel P, Salmi JI, Freissmuth M, Nanoff C.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Jan;365(1):8-16. Epub 2001 Nov 7.

PMID:
11862328
38.

Virally encoded 7TM receptors.

Rosenkilde MM, Waldhoer M, Lüttichau HR, Schwartz TW.

Oncogene. 2001 Mar 26;20(13):1582-93. Review.

39.

Tight association of the human Mel(1a)-melatonin receptor and G(i): precoupling and constitutive activity.

Roka F, Brydon L, Waldhoer M, Strosberg AD, Freissmuth M, Jockers R, Nanoff C.

Mol Pharmacol. 1999 Nov;56(5):1014-24.

PMID:
10531408
40.

Kinetics of ternary complex formation with fusion proteins composed of the A(1)-adenosine receptor and G protein alpha-subunits.

Waldhoer M, Wise A, Milligan G, Freissmuth M, Nanoff C.

J Biol Chem. 1999 Oct 22;274(43):30571-9.

41.

G protein antagonists.

Freissmuth M, Waldhoer M, Bofill-Cardona E, Nanoff C.

Trends Pharmacol Sci. 1999 Jun;20(6):237-45. Review.

PMID:
10366866
42.

Differential uncoupling of A1 adenosine and D2 dopamine receptors by suramin and didemethylated suramin (NF037).

Waldhoer M, Bofill-Cardona E, Milligan G, Freissmuth M, Nanoff C.

Mol Pharmacol. 1998 May;53(5):808-18.

PMID:
9584206
43.

Gsalpha-selective G protein antagonists.

Hohenegger M, Waldhoer M, Beindl W, Böing B, Kreimeyer A, Nickel P, Nanoff C, Freissmuth M.

Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):346-51.

44.

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