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Items: 1 to 50 of 70

1.

Intestinal parasites in Galapagos sea lions (Zalophus wollebaeki) Sivertsen, 1953 on San Cristóbal Island, Galápagos, Ecuador.

Walden H, Grijalva CJ, Paez-Rosas D, Hernandez J.

J Parasitol. 2018 Aug 29. doi: 10.1645/17-187. [Epub ahead of print]

PMID:
30141720
2.

Dog overpopulation and diagnosis of intestinal parasites on Santa Cruz Island, Galapagos 2016.

Diaz NM, Walden HS, Yoak A, McIntosh A, Duque V, Cruz M, Hernandez JA.

Prev Vet Med. 2018 Sep 1;157:99-104. doi: 10.1016/j.prevetmed.2018.06.003. Epub 2018 Jun 27.

PMID:
30086856
3.

Systemic humoral immunity in beef bulls following therapeutic vaccination against Tritrichomonas foetus.

Alling C, Rae DO, Ma X, Neumann L, Lollis LG, Steele E, Yelvington J, Naikare HK, Walden HS, Crews J, Boughton R.

Vet Parasitol. 2018 May 15;255:69-73. doi: 10.1016/j.vetpar.2018.03.028. Epub 2018 Mar 31.

PMID:
29773139
4.

RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation.

Bustos F, Segarra-Fas A, Chaugule VK, Brandenburg L, Branigan E, Toth R, Macartney T, Knebel A, Hay RT, Walden H, Findlay GM.

Cell Rep. 2018 May 8;23(6):1599-1611. doi: 10.1016/j.celrep.2018.04.022.

5.

RBR ligase-mediated ubiquitin transfer: a tale with many twists and turns.

Walden H, Rittinger K.

Nat Struct Mol Biol. 2018 May 7. doi: 10.1038/s41594-018-0063-3. [Epub ahead of print] Review.

PMID:
29735995
6.

Parkin function in Parkinson's disease.

Arkinson C, Walden H.

Science. 2018 Apr 20;360(6386):267-268. doi: 10.1126/science.aar6606. No abstract available.

PMID:
29674580
7.

Comparison of six commercial antigen kits for detection of Dirofilaria immitis infections in canines with necropsy-confirmed heartworm status.

Henry LG, Brunson KJ, Walden HS, Wenzlow N, Beachboard SE, L Barr K, Long MT.

Vet Parasitol. 2018 Apr 30;254:178-182. doi: 10.1016/j.vetpar.2018.02.037. Epub 2018 Feb 25.

PMID:
29657005
8.

Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.

Morreale FE, Testa A, Chaugule VK, Bortoluzzi A, Ciulli A, Walden H.

J Med Chem. 2017 Oct 12;60(19):8183-8191. doi: 10.1021/acs.jmedchem.7b01071. Epub 2017 Oct 3.

9.

Infection with a novel derogenid trematode in a Flap-necked chameleon (Chamaeleo dilepis).

Collicutt NB, Stacy NI, Walden HS, Childress A, Dill J, Anderson M, Wellehan JFX Jr.

Vet Clin Pathol. 2017 Dec;46(4):629-634. doi: 10.1111/vcp.12537. Epub 2017 Aug 17.

PMID:
28817168
10.

Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening.

Morreale FE, Bortoluzzi A, Chaugule VK, Arkinson C, Walden H, Ciulli A.

J Med Chem. 2017 May 11;60(9):4093-4098. doi: 10.1021/acs.jmedchem.7b00147. Epub 2017 May 2.

11.

Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.

Kumar A, Chaugule VK, Condos TEC, Barber KR, Johnson C, Toth R, Sundaramoorthy R, Knebel A, Shaw GS, Walden H.

Nat Struct Mol Biol. 2017 May;24(5):475-483. doi: 10.1038/nsmb.3400. Epub 2017 Apr 17.

12.

Ubiquitin and Parkinson's disease through the looking glass of genetics.

Walden H, Muqit MM.

Biochem J. 2017 Apr 13;474(9):1439-1451. doi: 10.1042/BCJ20160498. Review.

13.

Selective Nonoperative Management of Abdominal Gunshot Wounds from Heresy to Adoption: A Multicenter Study of the Research Consortium of New England Centers for Trauma (ReCoNECT).

Peponis T, Kasotakis G, Yu J, Alouidor R, Burkott B, Maung AA, Johnson DC, Saillant N, Walden H, Salim A, Bryant E, Dorfman JD, Klein EN, Elefant R, Tabrizi MB, Bugaev N, Arabian SS, Velmahos GC.

J Am Coll Surg. 2017 Jun;224(6):1036-1045. doi: 10.1016/j.jamcollsurg.2016.12.055. Epub 2017 Mar 1.

PMID:
28259545
14.

Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion.

Andreasson AS, Karamanou DM, Gillespie CS, Özalp F, Butt T, Hill P, Jiwa K, Walden HR, Green NJ, Borthwick LA, Clark SC, Pauli H, Gould KF, Corris PA, Ali S, Dark JH, Fisher AJ.

Eur J Cardiothorac Surg. 2017 Mar 1;51(3):577-586. doi: 10.1093/ejcts/ezw358.

15.

Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3.

Alpi AF, Chaugule V, Walden H.

Biochem J. 2016 Oct 15;473(20):3401-3419. Review.

16.

COCCIDIAL INFECTION OF THE ADRENAL GLANDS OF LEATHERBACK SEA TURTLES (DERMOCHELYS CORIACEA).

Ferguson SD, Wellehan JF Jr, Frasca S Jr, Innis CJ, Harris HS, Miller M, Weber ES, Walden HS, Greiner EC, Merigo C, Stacy BA.

J Wildl Dis. 2016 Oct;52(4):874-882. Epub 2016 Jul 25.

PMID:
27455196
17.

Types of Ubiquitin Ligases.

Morreale FE, Walden H.

Cell. 2016 Mar 24;165(1):248-248.e1. doi: 10.1016/j.cell.2016.03.003.

18.

Specificity and disease in the ubiquitin system.

Chaugule VK, Walden H.

Biochem Soc Trans. 2016 Feb;44(1):212-27. doi: 10.1042/BST20150209. Review.

19.

Dog overpopulation and burden of exposure to canine distemper virus and other pathogens on Santa Cruz Island, Galapagos.

Diaz NM, Mendez GS, Grijalva CJ, Walden HS, Cruz M, Aragon E, Hernandez JA.

Prev Vet Med. 2016 Jan 1;123:128-137. doi: 10.1016/j.prevetmed.2015.11.016. Epub 2015 Dec 8.

PMID:
26700426
20.

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.

Kumar A, Aguirre JD, Condos TE, Martinez-Torres RJ, Chaugule VK, Toth R, Sundaramoorthy R, Mercier P, Knebel A, Spratt DE, Barber KR, Shaw GS, Walden H.

EMBO J. 2015 Oct 14;34(20):2506-21. doi: 10.15252/embj.201592337. Epub 2015 Aug 7.

21.

The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL.

Miles JA, Frost MG, Carroll E, Rowe ML, Howard MJ, Sidhu A, Chaugule VK, Alpi AF, Walden H.

J Biol Chem. 2015 Aug 21;290(34):20995-1006. doi: 10.1074/jbc.M115.675835. Epub 2015 Jul 6.

22.

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.

Kazlauskaite A, Martínez-Torres RJ, Wilkie S, Kumar A, Peltier J, Gonzalez A, Johnson C, Zhang J, Hope AG, Peggie M, Trost M, van Aalten DM, Alessi DR, Prescott AR, Knebel A, Walden H, Muqit MM.

EMBO Rep. 2015 Aug;16(8):939-54. doi: 10.15252/embr.201540352. Epub 2015 Jun 25.

23.

The effects of being in a "new relationship" on levels of testosterone in men.

Farrelly D, Owens R, Elliott H, Walden H, Wetherell M.

Evol Psychol. 2015 Mar 17;13(1):250-61.

PMID:
25782185
24.

The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder.

Walden H, Deans AJ.

Annu Rev Biophys. 2014;43:257-78. doi: 10.1146/annurev-biophys-051013-022737. Review.

PMID:
24773018
25.

The effect of ex vivo lung perfusion on microbial load in human donor lungs.

Andreasson A, Karamanou DM, Perry JD, Perry A, Ӧzalp F, Butt T, Morley KE, Walden HR, Clark SC, Prabhu M, Corris PA, Gould K, Fisher AJ, Dark JH.

J Heart Lung Transplant. 2014 Sep;33(9):910-6. doi: 10.1016/j.healun.2013.12.023. Epub 2014 Jan 9.

PMID:
24631044
26.

RBR E3 ubiquitin ligases: new structures, new insights, new questions.

Spratt DE, Walden H, Shaw GS.

Biochem J. 2014 Mar 15;458(3):421-37. doi: 10.1042/BJ20140006. Review.

27.

Eosinophilic meningoencephalomyelitis in an orangutan (Pongo pygmaeus) caused by Angiostrongylus cantonensis.

Emerson JA, Walden HS, Peters RK, Farina LL, Fredholm DV, Qvarnstrom Y, Xayavong M, Bishop H, Slapcinsky J, McIntosh A, Wellehan JF Jr.

Vet Q. 2013 Dec;33(4):191-4. doi: 10.1080/01652176.2013.880005. No abstract available.

PMID:
24512524
28.

"STOP, LOOK, and LISTEN." Hepatic Portal Venous Gas: Time for Clinical Assessment!

Villa M, Ranade AN, Jaimes-Vanegas N, Walden H, D'Agostino CA, Nicastro J, Coppa GF, Sideridis K, Molmenti EP, Bagdonas RA.

Int J Angiol. 2013 Jun;22(2):123-6. doi: 10.1055/s-0032-1333066.

29.

Structure of the human FANCL RING-Ube2T complex reveals determinants of cognate E3-E2 selection.

Hodson C, Purkiss A, Miles JA, Walden H.

Structure. 2014 Feb 4;22(2):337-44. doi: 10.1016/j.str.2013.12.004. Epub 2014 Jan 2.

30.

Molecular replacements.

Ballard C, Roversi P, Walden H.

Acta Crystallogr D Biol Crystallogr. 2013 Nov;69(Pt 11):2165-6. doi: 10.1107/S0907444913027352. Epub 2013 Oct 18. No abstract available.

31.

Competitors who choose to be red have higher testosterone levels.

Farrelly D, Slater R, Elliott HR, Walden HR, Wetherell MA.

Psychol Sci. 2013 Oct;24(10):2122-4. doi: 10.1177/0956797613482945. Epub 2013 Aug 5. No abstract available.

PMID:
23917700
32.

A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.

Spratt DE, Martinez-Torres RJ, Noh YJ, Mercier P, Manczyk N, Barber KR, Aguirre JD, Burchell L, Purkiss A, Walden H, Shaw GS.

Nat Commun. 2013;4:1983. doi: 10.1038/ncomms2983.

33.

A new species of Tritrichomonas (Sarcomastigophora: Trichomonida) from the domestic cat (Felis catus).

Walden HS, Dykstra C, Dillon A, Rodning S, Givens D, Bird R, Newton J, Lindsay D.

Parasitol Res. 2013 Jun;112(6):2227-35. doi: 10.1007/s00436-013-3381-8. Epub 2013 Mar 24.

PMID:
23525691
34.

Kiricephalus coarctatus in an Eastern Indigo Snake (Drymarchon couperi); endoscopic removal, identification, and phylogeny.

Brock AP, Gallagher AE, Walden HD, Owen JL, Dunbar MD, Wamsley HL, Schoeller AB, Childress AL, Wellehan JF Jr.

Vet Q. 2012 Jun;32(2):107-12. doi: 10.1080/01652176.2012.709952. Epub 2012 Aug 2. No abstract available.

PMID:
22857002
35.

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.

Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M, Knebel A, Alessi DR, Muqit MM.

Open Biol. 2012 May;2(5):120080. doi: 10.1098/rsob.120080.

36.

Towards a molecular understanding of the fanconi anemia core complex.

Hodson C, Walden H.

Anemia. 2012;2012:926787. doi: 10.1155/2012/926787. Epub 2012 May 22.

37.

Regulation of Parkin E3 ubiquitin ligase activity.

Walden H, Martinez-Torres RJ.

Cell Mol Life Sci. 2012 Sep;69(18):3053-67. doi: 10.1007/s00018-012-0978-5. Epub 2012 Apr 19. Review.

PMID:
22527713
38.

Small, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation.

Burchell L, Chaugule VK, Walden H.

PLoS One. 2012;7(4):e34748. doi: 10.1371/journal.pone.0034748. Epub 2012 Apr 4.

39.

Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation.

O'Boyle G, Fox CR, Walden HR, Willet JD, Mavin ER, Hine DW, Palmer JM, Barker CE, Lamb CA, Ali S, Kirby JA.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4598-603. doi: 10.1073/pnas.1118104109. Epub 2012 Mar 5. Erratum in: Proc Natl Acad Sci U S A. 2012 May 15;109(20):7948.

40.

Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway.

Hodson C, Cole AR, Lewis LP, Miles JA, Purkiss A, Walden H.

J Biol Chem. 2011 Sep 16;286(37):32628-37. doi: 10.1074/jbc.M111.244632. Epub 2011 Jul 20.

41.

Autoregulation of Parkin activity through its ubiquitin-like domain.

Chaugule VK, Burchell L, Barber KR, Sidhu A, Leslie SJ, Shaw GS, Walden H.

EMBO J. 2011 Jun 21;30(14):2853-67. doi: 10.1038/emboj.2011.204.

42.

Hydrophobic, aromatic, and electrostatic interactions play a central role in amyloid fibril formation and stability.

Marshall KE, Morris KL, Charlton D, O'Reilly N, Lewis L, Walden H, Serpell LC.

Biochemistry. 2011 Mar 29;50(12):2061-71. doi: 10.1021/bi101936c. Epub 2011 Feb 22.

PMID:
21288003
43.

Ubiquitin signalling in DNA replication and repair.

Ulrich HD, Walden H.

Nat Rev Mol Cell Biol. 2010 Jul;11(7):479-89. doi: 10.1038/nrm2921. Epub 2010 Jun 16. Review.

PMID:
20551964
44.

Selenium incorporation using recombinant techniques.

Walden H.

Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):352-7. doi: 10.1107/S0907444909038207. Epub 2010 Mar 24. Review.

45.

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex.

Cole AR, Lewis LP, Walden H.

Nat Struct Mol Biol. 2010 Mar;17(3):294-8. doi: 10.1038/nsmb.1759. Epub 2010 Feb 14.

46.

Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.

Zhuang M, Calabrese MF, Liu J, Waddell MB, Nourse A, Hammel M, Miller DJ, Walden H, Duda DM, Seyedin SN, Hoggard T, Harper JW, White KP, Schulman BA.

Mol Cell. 2009 Oct 9;36(1):39-50. doi: 10.1016/j.molcel.2009.09.022.

47.

Recruiting African American girls and parents for a secondary weight gain prevention study.

Kennedy BM, Newton RL Jr, York-Crowe E, Walden HM, Ryan DH, White MA, Williamson DA.

J Cult Divers. 2008 Winter;15(4):181-6. Review.

PMID:
19202720
48.

Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway.

Walden HR, Kirby JA, Yeaman SJ, Gray J, Jones DE, Palmer JM.

Hepatology. 2008 Dec;48(6):1874-84. doi: 10.1002/hep.22540.

PMID:
19003917
49.

Intervening with coaches to promote awareness and prevention of weight pressures in cheerleaders.

Whisenhunt BL, Williamson DA, Drab-Hudson DL, Walden H.

Eat Weight Disord. 2008 Jun;13(2):102-10.

PMID:
18612259
50.

Slower eating rate reduces the food intake of men, but not women: implications for behavioral weight control.

Martin CK, Anton SD, Walden H, Arnett C, Greenway FL, Williamson DA.

Behav Res Ther. 2007 Oct;45(10):2349-59. Epub 2007 Apr 5.

PMID:
17517367

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