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Items: 1 to 50 of 163

1.

Acyltransferases and transacylases that determine the fatty acid composition of glycerolipids and the metabolism of bioactive lipid mediators in mammalian cells and model organisms.

Yamashita A, Hayashi Y, Nemoto-Sasaki Y, Ito M, Oka S, Tanikawa T, Waku K, Sugiura T.

Prog Lipid Res. 2014 Jan;53:18-81. doi: 10.1016/j.plipres.2013.10.001. Epub 2013 Oct 11. Review.

PMID:
24125941
2.

Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2gamma).

Yamashita A, Tanaka K, Kamata R, Kumazawa T, Suzuki N, Koga H, Waku K, Sugiura T.

Biochim Biophys Acta. 2009 Oct;1791(10):1011-22. doi: 10.1016/j.bbalip.2009.05.008. Epub 2009 Jun 6.

PMID:
19501189
4.

Topology of acyltransferase motifs and substrate specificity and accessibility in 1-acyl-sn-glycero-3-phosphate acyltransferase 1.

Yamashita A, Nakanishi H, Suzuki H, Kamata R, Tanaka K, Waku K, Sugiura T.

Biochim Biophys Acta. 2007 Sep;1771(9):1202-15. Epub 2007 Jul 17.

PMID:
17707131
5.

Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes.

Oka S, Arai S, Waku K, Tokumura A, Sugiura T.

J Biochem. 2007 May;141(5):687-97. Epub 2007 Mar 4.

PMID:
17339228
6.

Synthesis and biological evaluation of several structural analogs of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand.

Suhara Y, Oka S, Kittaka A, Takayama H, Waku K, Sugiura T.

Bioorg Med Chem. 2007 Jan 15;15(2):854-67. Epub 2006 Oct 27.

PMID:
17110113
7.

[Endogenous cannabinoid receptor ligands--anandamide and 2-arachidonoylglycerol].

Waku K.

Yakugaku Zasshi. 2006 Feb;126(2):67-81. Review. Japanese.

8.

Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum.

Maejima T, Oka S, Hashimotodani Y, Ohno-Shosaku T, Aiba A, Wu D, Waku K, Sugiura T, Kano M.

J Neurosci. 2005 Jul 20;25(29):6826-35.

9.

Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma).

Yamashita A, Kamata R, Kawagishi N, Nakanishi H, Suzuki H, Sugiura T, Waku K.

J Biochem. 2005 May;137(5):557-67.

PMID:
15944408
10.

Endogenous cannabinoid receptor ligand induces the migration of human natural killer cells.

Kishimoto S, Muramatsu M, Gokoh M, Oka S, Waku K, Sugiura T.

J Biochem. 2005 Feb;137(2):217-23.

PMID:
15749836
11.

Evidence for the involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation in mouse ear.

Oka S, Yanagimoto S, Ikeda S, Gokoh M, Kishimoto S, Waku K, Ishima Y, Sugiura T.

J Biol Chem. 2005 May 6;280(18):18488-97. Epub 2005 Mar 4.

12.

New perspectives in the studies on endocannabinoid and cannabis: 2-arachidonoylglycerol as a possible novel mediator of inflammation.

Sugiura T, Oka S, Gokoh M, Kishimoto S, Waku K.

J Pharmacol Sci. 2004 Dec;96(4):367-75. Epub 2004 Dec 15. Review.

13.
14.

2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils.

Oka S, Ikeda S, Kishimoto S, Gokoh M, Yanagimoto S, Waku K, Sugiura T.

J Leukoc Biol. 2004 Nov;76(5):1002-9. Epub 2004 Aug 17.

PMID:
15316028
15.

2,2-Functionalized analogues of 1alpha,25-dihydroxyvitamin D3, the potent inducers of cell differentiation.

Fujishima T, Kittaka A, Kurihara M, Saito N, Honzawa S, Kishimoto S, Sugiura T, Waku K, Takayama H.

J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):89-92.

PMID:
15225752
16.

2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells.

Kishimoto S, Kobayashi Y, Oka S, Gokoh M, Waku K, Sugiura T.

J Biochem. 2004 Apr;135(4):517-24.

17.

Concise synthesis and biological activities of 2alpha-alkyl- and 2alpha-(omega-hydroxyalkyl)-20-epi-1alpha,25-dihydroxyvitamin D3.

Honzawa S, Suhara Y, Nihei K, Saito N, Kishimoto S, Fujishima T, Kurihara M, Sugiura T, Waku K, Takayama H, Kittaka A.

Bioorg Med Chem Lett. 2003 Oct 20;13(20):3503-6.

PMID:
14505658
18.

Efficient synthesis of 2-modified 1alpha,25-dihydroxy-19-norvitamin D3 with Julia olefination: high potency in induction of differentiation on HL-60 cells.

Ono K, Yoshida A, Saito N, Fujishima T, Honzawa S, Suhara Y, Kishimoto S, Sugiura T, Waku K, Takayama H, Kittaka A.

J Org Chem. 2003 Sep 19;68(19):7407-15.

PMID:
12968893
19.

Ether-linked analogue of 2-arachidonoylglycerol (noladin ether) was not detected in the brains of various mammalian species.

Oka S, Tsuchie A, Tokumura A, Muramatsu M, Suhara Y, Takayama H, Waku K, Sugiura T.

J Neurochem. 2003 Jun;85(6):1374-81.

20.

Reverse reaction of lysophosphatidylinositol acyltransferase. Functional reconstitution of coenzyme A-dependent transacylation system.

Yamashita A, Watanabe M, Sato K, Miyashita T, Nagatsuka T, Kondo H, Kawagishi N, Nakanishi H, Kamata R, Sugiura T, Waku K.

J Biol Chem. 2003 Aug 8;278(32):30382-93. Epub 2003 May 19.

21.
22.

Lysophosphatidic acid, a growth factor-like lipid, in the saliva.

Sugiura T, Nakane S, Kishimoto S, Waku K, Yoshioka Y, Tokumura A.

J Lipid Res. 2002 Dec;43(12):2049-55.

23.

Synthesis and testing of 2alpha-modified 1alpha,25-dihydroxyvitamin D(3) analogues with a double side chain: marked cell differentiation activity.

Suhara Y, Kittaka A, Kishimoto S, Calverley MJ, Fujishima T, Saito N, Sugiura T, Waku K, Takayama H.

Bioorg Med Chem Lett. 2002 Nov 18;12(22):3255-8.

PMID:
12392726
24.

Cannabinoid receptors and their endogenous ligands.

Sugiura T, Waku K.

J Biochem. 2002 Jul;132(1):7-12. Review.

25.
26.

A convenient method for determination of the C20-22 PUFA composition of glycerolipids in blood and breast milk.

Ichihar K, Waku K, Yamaguchi C, Saito K, Shibahara A, Miyatani S, Yamamoto K.

Lipids. 2002 May;37(5):523-6.

PMID:
12056596
27.

Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance.

Sugiura T, Kobayashi Y, Oka S, Waku K.

Prostaglandins Leukot Essent Fatty Acids. 2002 Feb-Mar;66(2-3):173-92. Review.

PMID:
12052034
29.

Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids.

Tokumura A, Sinomiya J, Kishimoto S, Tanaka T, Kogure K, Sugiura T, Satouchi K, Waku K, Fukuzawa K.

Biochem J. 2002 Aug 1;365(Pt 3):617-28.

30.

2-arachidonoylglycerol: an endogenous cannabinoid receptor agonist.

Sugiura T, Waku K.

World Rev Nutr Diet. 2001;88:200-6. Review. No abstract available.

PMID:
11935957
31.

2-Arachidonoylglycerol and anandamide oppositely modulate norepinephrine release from the rat heart sympathetic nerves.

Kurihara J, Nishigaki M, Suzuki S, Okubo Y, Takata Y, Nakane S, Sugiura T, Waku K, Kato H.

Jpn J Pharmacol. 2001 Sep;87(1):93-6.

32.

Endogenous cannabinoid, 2-arachidonoylglycerol, attenuates naloxone-precipitated withdrawal signs in morphine-dependent mice.

Yamaguchi T, Hagiwara Y, Tanaka H, Sugiura T, Waku K, Shoyama Y, Watanabe S, Yamamoto T.

Brain Res. 2001 Aug 3;909(1-2):121-6.

PMID:
11478928
33.

Synthesis and biological activities of novel structural analogues of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand.

Suhara Y, Nakane S, Arai S, Takayama H, Waku K, Ishima Y, Sugiura T.

Bioorg Med Chem Lett. 2001 Aug 6;11(15):1985-8.

PMID:
11454463
34.
35.

ATP-independent fatty acyl-coenzyme A synthesis from phospholipid: coenzyme A-dependent transacylation activity toward lysophosphatidic acid catalyzed by acyl-coenzyme A:lysophosphatidic acid acyltransferase.

Yamashita A, Kawagishi N, Miyashita T, Nagatsuka T, Sugiura T, Kume K, Shimizu T, Waku K.

J Biol Chem. 2001 Jul 20;276(29):26745-52. Epub 2001 May 14.

37.

2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor.

Kagota S, Yamaguchi Y, Nakamura K, Sugiura T, Waku K, Kunitomo M.

Eur J Pharmacol. 2001 Mar;415(2-3):233-8.

PMID:
11275004
38.
39.

2-Arachidonoylglycerol and the cannabinoid receptors.

Sugiura T, Waku K.

Chem Phys Lipids. 2000 Nov;108(1-2):89-106. Review.

PMID:
11106784
40.

Synthesis and biological activities of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, and its metabolically stable ether-linked analogues.

Suhara Y, Takayama H, Nakane S, Miyashita T, Waku K, Sugiura T.

Chem Pharm Bull (Tokyo). 2000 Jul;48(7):903-7.

PMID:
10923815
41.

Occurrence of a novel cannabimimetic molecule 2-sciadonoylglycerol (2-eicosa-5',11',14'-trienoylglycerol) in the umbrella pine Sciadopitys verticillata seeds.

Nakane S, Tanaka T, Satouchi K, Kobayashi Y, Waku K, Sugiura T.

Biol Pharm Bull. 2000 Jun;23(6):758-61.

PMID:
10864031
42.

Images of interest. Gastrointestinal: what's in a hernia?

Shudo R, Saito T, Takahashi K, Horita K, Waku K, Aoyanagi Y.

J Gastroenterol Hepatol. 2000 May;15(5):565. No abstract available.

PMID:
10847446
43.

Acyl and alkyl ether-linked lysophosphatidic acids in the nervous system.

Sugiura T, Waku K, Tokumura A.

Ann N Y Acad Sci. 2000 Apr;905:351-3. No abstract available.

PMID:
10818481
44.

2-arachidonoylglycerol: a possible multifunctional lipid mediator in the nervous and immune systems.

Sugiura T, Waku K.

Ann N Y Acad Sci. 2000 Apr;905:344-6. Review. No abstract available.

PMID:
10818479
45.

Generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in picrotoxinin-administered rat brain.

Sugiura T, Yoshinaga N, Kondo S, Waku K, Ishima Y.

Biochem Biophys Res Commun. 2000 May 19;271(3):654-8.

PMID:
10814517
47.

Giant hydronephrosis due to a ureteral stone, and elevated serum levels of CA 19-9.

Shudo R, Saito T, Takahashi K, Horita K, Waku K, Honma I, Sato T.

Intern Med. 1999 Nov;38(11):887-91. Review.

48.

Occurrence of lysophosphatidic acid and its alkyl ether-linked analog in rat brain and comparison of their biological activities toward cultured neural cells.

Sugiura T, Nakane S, Kishimoto S, Waku K, Yoshioka Y, Tokumura A, Hanahan DJ.

Biochim Biophys Acta. 1999 Sep 22;1440(2-3):194-204.

PMID:
10521703
49.

[2-Arachidonoylglycerol: an endogenous cannabinoid receptor agonist].

Sugiura T, Kondo S, Nakane S, Waku K.

Tanpakushitsu Kakusan Koso. 1999 Jun;44(8 Suppl):1104-10. Review. Japanese. No abstract available.

PMID:
10396990
50.

Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds.

Sugiura T, Kodaka T, Nakane S, Miyashita T, Kondo S, Suhara Y, Takayama H, Waku K, Seki C, Baba N, Ishima Y.

J Biol Chem. 1999 Jan 29;274(5):2794-801.

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